J. Lemesre

Most-cited papers

1. Axenically cultured amastigote forms as an in vitro model for investigation of antileishmanial agents

   D. Sereno, J. Lemesre

   1997Antimicrobial Agents and Chemotherapy256 citations Open access

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2. Long-lasting protection against canine visceral leishmaniasis using the LiESAp-MDP vaccine in endemic areas of France: double-blind randomised efficacy field trial.

   J. Lemesre, P. Holzmuller, R. B. Goncalves, G. Bourdoiseau +3 more

   2007Vaccine164 citations

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3. Protection against experimental visceral leishmaniasis infection in dogs immunized with purified excreted secreted antigens of Leishmania infantum promastigotes.

   J. Lemesre, P. Holzmuller, M. Cavaleyra, R. B. Goncalves +2 more

   2005Vaccine163 citations

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4. Axenically Grown Amastigotes of Leishmania infantum Used as an In Vitro Model To Investigate the Pentavalent Antimony Mode of Action

   D. Sereno, M. Cavaleyra, K. Zemzoumi, S. Maquaire +2 more

   1998Antimicrobial Agents and Chemotherapy162 citations Open access

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5. Antimonial-Mediated DNA Fragmentation inLeishmania infantum Amastigotes

   D. Sereno, P. Holzmuller, Isabelle Mangot, G. Cuny +2 more

   2001Antimicrobial Agents and Chemotherapy154 citations Open access

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6. Nitric oxide-mediated cytostatic activity on Trypanosoma brucei gambiense and Trypanosoma brucei brucei.

   P. Vincendeau, S. Daulouède, B. Veyret, M. Dardé +2 more

   1992Experimental parasitology154 citations

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7. The C-type lectin receptors dectin-1, MR, and SIGNR3 contribute both positively and negatively to the macrophage response to Leishmania infantum.

   L. Lefèvre, G. Lugo-Villarino, E. Meunier, Alexis Valentin +10 more

   2013Immunity131 citations Open access

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8. Nitric Oxide-Mediated Proteasome-Dependent Oligonucleosomal DNA Fragmentation in Leishmania amazonensis Amastigotes

   P. Holzmuller, D. Sereno, M. Cavaleyra, Isabelle Mangot +3 more

   2002Infection and Immunity126 citations Open access

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9. DNA Transformation of Leishmania infantum Axenic Amastigotes and Their Use in Drug Screening

   D. Sereno, G. Roy, J. Lemesre, B. Papadopoulou +1 more

   2001Antimicrobial Agents and Chemotherapy120 citations Open access

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10. Leishmania spp.: nitric oxide-mediated metabolic inhibition of promastigote and axenically grown amastigote forms.

    J. Lemesre, Denis Sereno, Sylvie Daulouède, Bernard Veyret +2 more

    1997Experimental parasitology87 citations

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11. Infectivity of Leishmania braziliensis promastigotes is dependent on the increasing expression of a 65,000-dalton surface antigen.

    M. Kweider, J. Lemesre, F. Darcy, J. Kusnierz +2 more

    1987Journal of Immunology85 citations

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12. Use of an enzymatic micromethod to quantify amastigote stage of Leishmania amazonensis in vitro

    D. Sereno, J. Lemesre

    1997Parasitology Research81 citations

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13. Cytoplasmic SIR2 homologue overexpression promotes survival of Leishmania parasites by preventing programmed cell death.

    B. Vergnes, D. Sereno, Niloufar Madjidian-Sereno, J. Lemesre +1 more

    2002Gene80 citations

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14. Leishmania spp: completely defined medium without serum and macromolecules (CDM/LP) for the continuous in vitro cultivation of infective promastigote forms.

    Timothee Merlen, D. Sereno, Nathalie Brajon, Florence Rostand +1 more

    1999American Journal of Tropical Medicine and Hygiene79 citations

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15. Correlation of high serum levels of tumor necrosis factor-alpha with disease severity in human African trypanosomiasis.

    M. Okomo-Assoumou, S. Daulouède, J. Lemesre, Alexis N'Zila-Mouanda +1 more

    1995American Journal of Tropical Medicine and Hygiene78 citations

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16. Lymphocytes of dogs immunised with purified excreted-secreted antigens of Leishmania infantum co-incubated with Leishmania infected macrophages produce IFN gamma resulting in nitric oxide-mediated amastigote apoptosis.

    Philippe Holzmuller, Mireille Cavaleyra, J. Moreaux, R. Kovacic +3 more

    2005Veterinary Immunology and Immunopathology73 citations

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17. Spirolactone iridoids might be responsible for the antileishmanial activity of a Peruvian traditional remedy made with Himatanthus sucuuba (Apocynaceae).

    D. Castillo, J. Arevalo, F. Herrera, C. Ruiz +7 more

    2007Journal of Ethnopharmacology72 citations Open access

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18. Human Macrophage Tumor Necrosis Factor (TNF)–α Production Induced by Trypanosoma brucei gambiense and the Role of TNF-α in Parasite Control

    S. Daulouède, B. Bouteille, D. Moynet, P. De Baetselier +5 more

    200159 citations Open access

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19. Tolerance to Trypanosomatids: A Threat, or a Key for Disease Elimination?

    D. Berthier, S. Brenière, R. Bras-Gonçalves, J. Lemesre +5 more

    2016Trends in Parasitology58 citations

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20. Escaping Deleterious Immune Response in Their Hosts: Lessons from Trypanosomatids

    A. Geiger, G. Bossard, D. Sereno, Joana Pissarra +3 more

    2016Frontiers in Immunology58 citations Open access

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21. Role of CD8+ T cells in protection against Leishmania donovani infection in healed Visceral Leishmaniasis individuals

    H. Kaushal, R. Bras-Gonçalves, N. Negi, J. Lemesre +2 more

    2014BMC Infectious Diseases58 citations Open access

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22. Phenotypical characteristics, biochemical pathways, molecular targets and putative role of nitric oxide-mediated programmed cell death in Leishmania

    P. Holzmuller, R. Bras-Gonçalves, J. Lemesre

    2006Parasitology58 citations

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23. In Vitro Evaluation of a Soluble Leishmania Promastigote Surface Antigen as a Potential Vaccine Candidate against Human Leishmaniasis

    Rym Chamakh-Ayari, R. Bras-Gonçalves, Nargès Bahi-Jaber, Elodie Petitdidier +18 more

    2014PLoS ONE53 citations Open access

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24. Effective humoral and cellular immunoprotective responses in Li ESAp-MDP vaccinated protected dogs.

    G. Bourdoiseau, C. Hugnet, R. B. Goncalves, F. Vezilier +3 more

    2009Veterinary Immunology and Immunopathology51 citations

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25. Leishmania major: Cell type dependent distribution of a 43 kDa antigen related to silent information regulatory‐2 protein family

    K. Zemzoumi, D. Sereno, C. François, E. Guilvard +2 more

    1998Biology of the Cell47 citations

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26. Efficacy of second line drugs on antimonyl-resistant amastigotes of Leishmania infantum.

    D. Sereno, P. Holzmuller, J. Lemesre

    2000Acta Tropica45 citations

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27. Leishmania infantum amastigotes resistant to nitric oxide cytotoxicity: Impact on in vitro parasite developmental cycle and metabolic enzyme activities.

    P. Holzmuller, M. Hide, D. Sereno, J. Lemesre

    2006Infection, Genetics and Evolution43 citations

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28. In vitro life cycle of pentamidine-resistant amastigotes: stability of the chemoresistant phenotypes is dependent on the level of resistance induced

    Denis Sereno, J. Lemesre

    1997Antimicrobial Agents and Chemotherapy39 citations Open access

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29. Development of metacyclic Leishmania promastigotes is associated with the increasing expression of GP65, the major surface antigen

    M. Kweider, J. Lemesre, F. Santoro, J. Kusnierz +2 more

    1989Parasite immunology (Print)37 citations

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30. Requirements of defined cultivation conditions for standard growth of Leishmania promastigotes in vitro.

    J. Lemesre, F. Darcy, M. Kweider, A. Capron +1 more

    1988Acta Tropica37 citations

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31. Serodiagnosis of sleeping sickness in the Republic of the Congo: comparison of indirect immunofluorescent antibody test and card agglutination test.

    F. Noireau, J. Lemesre, M. Nzoukoudi, M. T. Louembet +2 more

    1988Transactions of the Royal Society of Tropical Medicine and Hygiene36 citations

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32. Recombinant Forms of Leishmania amazonensis Excreted/Secreted Promastigote Surface Antigen (PSA) Induce Protective Immune Responses in Dogs

    Elodie Petitdidier, J. Pagniez, G. Papierok, P. Vincendeau +2 more

    2016PLoS Neglected Tropical Diseases34 citations Open access

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33. Continuous in vitro culture of Babesia divergens in a serum-free medium

    N. Grande, É. Précigout, M. Ancelin, K. Moubri +4 more

    1997Parasitology34 citations

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34. Comparisons of immunological tests for serodiagnosis of Chagas disease in Bolivian patients.

    S. Brenière, R. Carrasco, H. Miguez, J. Lemesre +1 more

    1985Tropical and geographical medicine32 citations

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35. Circulating antibodies directed against tryptophan-like epitopes in sera of patients with human African trypanosomiasis.

    M. Okomo-Assoumou, M. Geffard, S. Daulouède, C. Chaugier +2 more

    1995American Journal of Tropical Medicine and Hygiene31 citations

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36. Experimental studies on the evolution of antimony-resistant phenotype during the in vitro life cycle of Leishmania infantum: implications for the spread of chemoresistance in endemic areas.

    Denis Sereno, E. Guilvard, S. Maquaire, Mireille Cavaleyra +3 more

    2001Acta Tropica30 citations

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37. ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ ◆ CHAPTER 6 Understanding Human Leishmaniasis : The Need for an Integrated Approach

    M. Hide, B. Bucheton, S. Kamhawi, R. Bras-Gonçalves +2 more

    200729 citations

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38. Lower Nitric Oxide Susceptibility of Trivalent Antimony-Resistant Amastigotes of Leishmania infantum

    Philippe Holzmuller, Denis Sereno, J. Lemesre

    2005Antimicrobial Agents and Chemotherapy29 citations Open access

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39. Peptide-based vaccine successfully induces protective immunity against canine visceral leishmaniasis

    Elodie Petitdidier, J. Pagniez, Joana Pissarra, P. Holzmuller +4 more

    2019npj Vaccines28 citations Open access

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40. Human macrophage tumor necrosis factor (TNF)-alpha production induced by Trypanosoma brucei gambiense and the role of TNF-alpha in parasite control.

    Sylvie Daulouède, Bernard Bouteille, D. Moynet, P. De Baetselier +5 more

    2001Journal of Infectious Diseases28 citations

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41. The epidemiological importance of the animal reservoir of Trypanosoma brucei gambiense in the Congo. 2. Characterization of the Trypanosoma brucei complex.

    François Noireau, P. Paindavoine, J. Lemesre, A. Toudic +4 more

    1989Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ)27 citations

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42. The separation of trypanosomes from blood by anion exchange chromatography: From Sheila Lanham’s discovery 50 years ago to a gold standard for sleeping sickness diagnosis

    V. Lejon, P. Büscher, R. Nzoumbou-Boko, G. Bossard +6 more

    2019PLoS Neglected Tropical Diseases24 citations Open access

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43. Evaluation of cellular immunological responses in mono‐ and polymorphic clinical forms of post‐kala‐azar dermal leishmaniasis in India

    H. Kaushal, R. Bras-Gonçalves, K. Avishek, D. K. Deep +6 more

    2016Clinical and Experimental Immunology24 citations Open access

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44. Subspecies-specific surface antigens of promastigotes of the Leishmania donovani complex

    J. Lemesre, F. Rizvi, D. Afchain, M. Sadigursky +2 more

    1985Infection and Immunity24 citations Open access

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45. Design of multi-epitope peptides containing HLA class-I and class-II-restricted epitopes derived from immunogenic Leishmania proteins, and evaluation of CD4+ and CD8+ T cell responses induced in cured cutaneous leishmaniasis subjects

    S. Hamrouni, R. Bras-Gonçalves, A. Kidar, K. Aoun +6 more

    2020PLoS Neglected Tropical Diseases22 citations Open access

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46. Specific and sensitive immunological diagnosis of Chagas' disease by competitive antibody enzyme immunoassay using a Trypanosoma cruzi-specific monoclonal antibody.

    J. Lemesre, D. Afchain, A. Capron, Y. Carlier +7 more

    1986American Journal of Tropical Medicine and Hygiene22 citations

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47. Additional data on Trypanosoma cruzi isozymic strains encountered in Bolivian domestic transmission cycles.

    M. Tibayrenc, A. Hoffmann, O. Poch, L. Echalar +4 more

    1986Transactions of the Royal Society of Tropical Medicine and Hygiene21 citations

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48. Different monoclonal antibodies against the component 5 specific for Trypanosoma cruzi.

    O. Orozco, D. Afchain, Colette Dissous, C. Rodriguez +4 more

    1984American Journal of Tropical Medicine and Hygiene21 citations

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49. The Trypanosoma brucei gambiense Secretome Impairs Lipopolysaccharide-Induced Maturation, Cytokine Production, and Allostimulatory Capacity of Dendritic Cells

    E. Garzón, P. Holzmuller, R. Bras-Gonçalves, P. Vincendeau +3 more

    2013Infection and Immunity20 citations Open access

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50. Trypanosomatid Infections: How Do Parasites and Their Excreted–Secreted Factors Modulate the Inducible Metabolism of l-Arginine in Macrophages?

    P. Holzmuller, A. Geiger, R. Nzoumbou-Boko, Joana Pissarra +6 more

    2018Frontiers in Immunology18 citations Open access

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