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Said A Hassounah · SciRah

Researcher profile · Semantic Scholar

Said A Hassounah

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Said A Hassounah — researcher profile on SciRah

h-index: 12
Works: 28
Citations: 610

Most-cited papers

Evaluation of Sofosbuvir (β-D-2′-deoxy-2′-α-fluoro-2′-β-C-methyluridine) as an inhibitor of Dengue virus replication#
Hong-Tao Xu, S. Colby-Germinario, Said A Hassounah, Clare Fogarty +6 more
2017Scientific Reports77 citations Open access
Semantic Scholar
Differential Effects of the G118R, H51Y, and E138K Resistance Substitutions in Different Subtypes of HIV Integrase
P. Quashie, Maureen Oliviera, Tamar Veres, Nathan Osman +6 more
2014Journal of Virology73 citations Open access
Semantic Scholar
Purification of Zika virus RNA-dependent RNA polymerase and its use to identify small-molecule Zika inhibitors
Hong-Tao Xu, Said A Hassounah, S. Colby-Germinario, Maureen Oliveira +8 more
2017Journal of Antimicrobial Chemotherapy72 citations Open access
Semantic Scholar
Biochemical Analysis of the Role of G118R-Linked Dolutegravir Drug Resistance Substitutions in HIV-1 Integrase
P. Quashie, T. Mesplède, Yingshan Han, Tamar Veres +5 more
2013Antimicrobial Agents and Chemotherapy68 citations Open access
Semantic Scholar
Addition of E138K to R263K in HIV integrase increases resistance to dolutegravir, but fails to restore activity of the HIV integrase enzyme and viral replication capacity.
T. Mesplède, Nathan Osman, Melissa Wares, P. Quashie +5 more
2014Journal of Antimicrobial Chemotherapy48 citations Open access
Semantic Scholar
Antiviral Activity of Bictegravir and Cabotegravir against Integrase Inhibitor-Resistant SIVmac239 and HIV-1
Said A Hassounah, A. Alikhani, Maureen Oliveira, S. Bharaj +6 more
2017Antimicrobial Agents and Chemotherapy38 citations Open access
Semantic Scholar
The S230R Integrase Substitution Associated With Virus Load Rebound During Dolutegravir Monotherapy Confers Low-Level Resistance to Integrase Strand-Transfer Inhibitors
H. T. Pham, L. Labrie, I. Wijting, Said A Hassounah +12 more
2018Journal of Infectious Diseases35 citations Open access
Semantic Scholar
Identification of a Pyridoxine-Derived Small-Molecule Inhibitor Targeting Dengue Virus RNA-Dependent RNA Polymerase
Hong-Tao Xu, S. Colby-Germinario, Said A Hassounah, P. Quashie +4 more
2015Antimicrobial Agents and Chemotherapy34 citations Open access
Semantic Scholar
Effect of HIV-1 Integrase Resistance Mutations When Introduced into SIVmac239 on Susceptibility to Integrase Strand Transfer Inhibitors
Said A Hassounah, T. Mesplède, P. Quashie, Maureen Oliveira +2 more
2014Journal of Virology24 citations Open access
Semantic Scholar
Monotherapy with either dolutegravir or raltegravir fails to durably suppress HIV viraemia in humanized mice
A. Heredia, Said A Hassounah, S. Medina-Moreno, J. Zapata +7 more
2017Journal of Antimicrobial Chemotherapy18 citations Open access
Semantic Scholar
Structural Studies of the HIV-1 Integrase Protein: Compound Screening and Characterization of a DNA-Binding Inhibitor
P. Quashie, Yingshan Han, Said A Hassounah, T. Mesplède +1 more
2015PLoS ONE18 citations Open access
Semantic Scholar
The R263K substitution in HIV-1 subtype C is more deleterious for integrase enzymatic function and viral replication than in subtype B
T. Mesplède, P. Quashie, Said A Hassounah, Nathan Osman +4 more
2015AIDS (London)17 citations Open access
Semantic Scholar
Where are we with injectables against HIV infection and what are the remaining challenges?
Said A Hassounah, T. Mesplède
2018Expert Review of Anti-Infective Therapy11 citations
Semantic Scholar
Dolutegravir Monotherapy of Simian Immunodeficiency Virus-Infected Macaques Selects for Several Patterns of Resistance Mutations with Variable Virological Outcomes
K. V. Van Rompay, Said A Hassounah, B. Keele, J. Lifson +8 more
2018Journal of Virology11 citations Open access
Semantic Scholar
The R262K Substitution Combined with H51Y in HIV-1 Subtype B Integrase Confers Low-Level Resistance against Dolutegravir
Vincent Cutillas, T. Mesplède, Kaitlin Anstett, Said A Hassounah +1 more
2014Antimicrobial Agents and Chemotherapy10 citations Open access
Semantic Scholar
The dual CCR5 and CCR2 inhibitor cenicriviroc does not redistribute HIV into extracellular space: implications for plasma viral load and intracellular DNA decline.
Victor G. Kramer, Said A Hassounah, S. Colby-Germinario, Maureen Oliveira +3 more
2015Journal of Antimicrobial Chemotherapy9 citations Open access
Semantic Scholar
Simian-Tropic HIV as a Model To Study Drug Resistance against Integrase Inhibitors
Melissa Wares, Said A Hassounah, T. Mesplède, P. Sandstrom +1 more
2015Antimicrobial Agents and Chemotherapy9 citations Open access
Semantic Scholar
Characterization of the Drug Resistance Profiles of Integrase Strand Transfer Inhibitors in Simian Immunodeficiency Virus SIVmac239
Said A Hassounah, Yan-Na Liu, P. Quashie, Maureen Oliveira +5 more
2015Journal of Virology7 citations Open access
Semantic Scholar
Evaluation of Sofosbuvir (β-D-2′-deoxy-2′-α-fluoro-2′-β-C-methyluridine) as an inhibitor of Dengue virus replication#
Hong-Tao Xu, S. Colby-Germinario, Said A Hassounah, Clare Fogarty +6 more
2017Scientific Reports6 citations Open access
Semantic Scholar
Biochemical Analysis of the Role of G118R-Linked Dolutegravir Drug Resistance Substitutions in HIV-1 Integrase
P. Quashie, T. Mesplède, Yingshan Han, Tamar Veres +5 more
2014Antimicrobial Agents and Chemotherapy6 citations Open access
Semantic Scholar
8th IAS Conference on HIV Pathogenesis, Treatment & Prevention 19–22 July 2015, Vancouver, Canada
Kelly A. Metcalf Pate, Christopher W. Pohlmeyer, Victoria Walker-Sperling, J. Foote +496 more
2015Journal of the International AIDS Society5 citations Open access
Semantic Scholar
Nonhuman Primates and Humanized Mice for Studies of HIV-1 Integrase Inhibitors: A Review
Said A Hassounah, T. Mesplède, M. Wainberg
2016Pathogens and Immunity4 citations Open access
Semantic Scholar
Cenicriviroc blocks HIV entry but does not lead to redistribution of HIV into extracellular space like maraviroc
Victor G. Kramer, Said A Hassounah, S. Colby-Germinario, T. Mesplède +2 more
2014Journal of the International AIDS Society4 citations Open access
Semantic Scholar
Insertion as resistance mechanism against integrase inhibitors in several retroviruses.
H. Pham, Said A Hassounah, B. Keele, K. V. Van Rompay +1 more
2019Clinical Infectious Diseases3 citations Open access
Semantic Scholar
Durable suppression of HIV-1 with resistance mutations to integrase inhibitors by dolutegravir following drug washout
Nathan Osman, T. Mesplède, Maureen Oliveira, Said A Hassounah +2 more
2018AIDS (London)2 citations
Semantic Scholar
Lamivudine-resistant HIVM184V is Durably Suppressed with Dolutegravir plus Lamivudine Dual Therapy in Humanized Mice.
S. Medina-Moreno, J. Zapata, F. Kashanchi, Nhut M. Le +5 more
2020Journal of Global Antimicrobial Resistance1 citations Open access
Semantic Scholar
Biochemical Analysis of the Role of G118R-Linked Dolutegravir Drug Resistance Substitutions in HIV-1 Integrase
P. Quashie, T. Mesplède, Yingshan Han, Tamar Veres +5 more
2014Antimicrobial Agents and Chemotherapy1 citations Open access
Semantic Scholar
The Effect of HIV-1 Integrase Resistance Mutations when Introduced into 1
Said A Hassounah, T. Mesplède, P. Quashie, Maureen Oliveira +2 more
20140 citations
Semantic Scholar

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