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P. Hoffman · SciRah

Researcher profile · Semantic Scholar

P. Hoffman

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P. Hoffman — researcher profile on SciRah

h-index: 52
Works: 236
Citations: 10K

Most-cited papers

Effects of moderate alcohol consumption on the central nervous system.
M. Eckardt, S. File, G. Gessa, K. Grant +6 more
1998Alcoholism: Clinical and Experimental Research660 citations
Semantic Scholar
Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis.
M. Mulligan, I. Ponomarev, R. Hitzemann, J. Belknap +11 more
2006Proceedings of the National Academy of Sciences of the United States of America375 citations
Semantic Scholar
Brain-Derived Neurotrophic Factor Mediates the Anti-Apoptotic Effect of NMDA in Cerebellar Granule Neurons: Signal Transduction Cascades and Site of Ethanol Action
Sanjiv V. Bhave, L. Ghoda, P. Hoffman
1999Journal of Neuroscience211 citations Open access
Semantic Scholar
Regional and subunit specific changes in NMDA receptor mRNA and immunoreactivity in mouse brain following chronic ethanol ingestion.
Lawrence D. Snell, K. Nunley, R. Lickteig, Michael Browning +2 more
1996Brain Research. Molecular Brain Research194 citations
Semantic Scholar
Genetical genomic determinants of alcohol consumption in rats and humans
B. Tabakoff, L. Saba, M. Printz, P. Flodman +17 more
2009BMC Biology159 citations Open access
Semantic Scholar
Ethanol Promotes Apoptosis in Cerebellar Granule Cells by Inhibiting the Trophic Effect of NMDA
Sanjiv V. Bhave, P. Hoffman
1997Journal of Neurochemistry140 citations
Semantic Scholar
The Neurobiology of Alcohol Consumption and Alcoholism: An Integrative History
B. Tabakoff, P. Hoffman
2013Pharmacology, Biochemistry and Behavior137 citations Open access
Semantic Scholar
Alcohol addiction: an enigma among us.
B. Tabakoff, P. Hoffman
1996Neuron132 citations Open access
Semantic Scholar
How Adaptation of the Brain to Alcohol Leads to Dependence
P. Clapp, Sanjiv V. Bhave, P. Hoffman
2008Alcohol Research and Health131 citations
Semantic Scholar
Selective Breeding, Quantitative Trait Locus Analysis, and Gene Arrays Identify Candidate Genes for Complex Drug-Related Behaviors
B. Tabakoff, Sanjiv V. Bhave, P. Hoffman
2003Journal of Neuroscience95 citations Open access
Semantic Scholar
Alcohol dependence: a commentary on mechanisms.
P. Hoffman, B. Tabakoff
1996Alcohol and Alcoholism90 citations
Semantic Scholar
The characterization of a novel human adenylyl cyclase which is present in brain and other tissues
Kaisa Hellevuo, Masami Yoshimura, N. Mons, P. Hoffman +2 more
1995Journal of Biological Chemistry79 citations Open access
Semantic Scholar
The genomic determinants of alcohol preference in mice
B. Tabakoff, L. Saba, K. Kechris, Wei Hu +4 more
2008Mammalian Genome77 citations Open access
Semantic Scholar
Attenuation of glutamate-induced neurotoxicity in chronically ethanol-exposed cerebellar granule cells by NMDA receptor antagonists and ganglioside GM1.
P. Hoffman, Karen R. Iorio, Lawrence D. Snell, Boris Tabakoff
1995Alcoholism: Clinical and Experimental Research72 citations
Semantic Scholar
Animal Models in Alcohol Research
B. Tabakoff, P. Hoffman
2000Alcohol Research and Health68 citations
Semantic Scholar
Candidate genes and their regulatory elements: alcohol preference and tolerance
L. Saba, Sanjiv V. Bhave, N. Grahame, P. Bice +4 more
2006Mammalian Genome66 citations
Semantic Scholar
NMDA receptors in alcoholism.
P. Hoffman
2003International review of neurobiology59 citations
Semantic Scholar
Glutamate receptors in alcohol withdrawal-induced neurotoxicity
P. Hoffman
1995Metabolic brain disease59 citations
Semantic Scholar
A Systems Genetic Analysis of Alcohol Drinking by Mice, Rats and Men: Influence of Brain GABAergic Transmission
L. Saba, B. Bennett, P. Hoffman, Kelsey Barcomb +3 more
2010Neuropharmacology52 citations Open access
Semantic Scholar
Sex Differences in the Brain Transcriptome Related to Alcohol Effects and Alcohol Use Disorder
R. Hitzemann, S. Bergeson, A. E. Berman, J. Bubier +18 more
2021Biological Psychiatry50 citations Open access
Semantic Scholar
The PhenoGen Informatics website: tools for analyses of complex traits
Sanjiv V. Bhave, Cheryl K. Hornbaker, T. Phang, L. Saba +16 more
2007BMC Genetics50 citations Open access
Semantic Scholar
Gene expression in brain: a window on ethanol dependence, neuroadaptation, and preference.
P. Hoffman, M. Miles, H. Edenberg, W. Sommer +3 more
2003Alcoholism: Clinical and Experimental Research50 citations
Semantic Scholar
Mechanism of ethanol inhibition of NMDA receptor function in primary cultures of cerebral cortical cells.
Sanjiv V. Bhave, L. Snell, B. Tabakoff, P. Hoffman
1996Alcoholism: Clinical and Experimental Research50 citations
Semantic Scholar
Genomic Insights into Acute Alcohol Tolerance
Wei Hu, L. Saba, K. Kechris, Sanjiv V. Bhave +2 more
2008Journal of Pharmacology and Experimental Therapeutics48 citations Open access
Semantic Scholar
Phosphorylation Regulates Removal of Synaptic N-Methyl-d-Aspartate Receptors after Withdrawal from Chronic Ethanol Exposure
P. Clapp, Emily S. Gibson, M. Dell'Acqua, P. Hoffman
2010Journal of Pharmacology and Experimental Therapeutics47 citations Open access
Semantic Scholar
Genetic Markers of Co-Morbid Depression and Alcoholism in Women
D. Procopio, L. Saba, H. Walter, O. Lesch +6 more
2012Alcoholism: Clinical and Experimental Research45 citations Open access
Semantic Scholar
A Sex-Specific Role of Type VII Adenylyl Cyclase in Depression
L. Hines, P. Hoffman, Sanjiv V. Bhave, L. Saba +10 more
2006Journal of Neuroscience45 citations Open access
Semantic Scholar
Phosphatidylinositol 3′‐OH kinase and protein kinase A pathways mediate the anti‐apoptotic effect of pituitary adenylyl cyclase‐activating polypeptide in cultured cerebellar granule neurons: modulation by ethanol
Sanjiv V. Bhave, P. Hoffman
2003Journal of Neurochemistry43 citations
Semantic Scholar
Acute Effects of Ethanol on Pharmacologically Isolated Kainate Receptors in Cerebellar Granule Neurons: Comparison with NMDA and AMPA Receptors
C. Valenzuela, Sanjiv V. Bhave, P. Hoffman, R. Harris
1998Journal of Neurochemistry43 citations
Semantic Scholar
Overexpression of type 7 adenylyl cyclase in the mouse brain enhances acute and chronic actions of morphine.
Masami Yoshimura, Peter H. Wu, P. Hoffman, B. Tabakoff
2000Molecular Pharmacology41 citations
Semantic Scholar
Phosphorylation cascades control the actions of ethanol on cell cAMP signalling.
Boris Tabakoff, E. Nelson, Masami Yoshimura, Kaisa Hellevuo +1 more
2001Journal of Biomedical Sciences38 citations
Semantic Scholar
Platelet adenylyl cyclase activity as a trait marker of alcohol dependence. WHO/ISBRA Collaborative Study Investigators. International Society for Biomedical Research on Alcoholism.
J. Menninger, A. Barón, K. Conigrave, John B. Whitfield +6 more
2000Alcoholism: Clinical and Experimental Research37 citations
Semantic Scholar
Platelet adenylyl cyclase activity in alcoholics and subtypes of alcoholics. WHO/ISBRA Study Clinical Centers.
A. Parsian, R. Todd, C. Robert Cloninger, P. Hoffman +3 more
1996Alcoholism: Clinical and Experimental Research37 citations
Semantic Scholar
Immunological assessment of the distribution of type VII adenylyl cyclase in brain.
N. Mons, M. Yoshimura, H. Ikeda, P. Hoffman +1 more
1998Brain Research35 citations
Semantic Scholar
Whole Brain and Brain Regional Coexpression Network Interactions Associated with Predisposition to Alcohol Consumption
L. Vanderlinden, L. Saba, K. Kechris, M. Miles +2 more
2013PLoS ONE33 citations Open access
Semantic Scholar
Antagonism of the behavioral effects of ethanol by naltrexone in BALB/c, C57BL/6, and DBA/2 mice
K. Kiianmaa, P. Hoffman, B. Tabakoff
2004Psychopharmacology32 citations
Semantic Scholar
The 71 kDa glutamate-binding protein is increased in cerebellar granule cells after chronic ethanol treatment.
P. Hoffman, Sanjiv V. Bhave, Keshava N. Kumar, K. Iorio +3 more
1996Brain Research. Molecular Brain Research32 citations
Semantic Scholar
Adenylyl cyclases and alcohol.
Boris Tabakoff, P. Hoffman
1998Advances in second messenger and phosphoprotein research30 citations
Semantic Scholar
Chronic ethanol exposure delays the ‘developmental switch’ of the NMDA receptor 2A and 2B subunits in cultured cerebellar granule neurons
L. Snell, Sanjiv V. Bhave, B. Tabakoff, P. Hoffman
2001Journal of Neurochemistry28 citations
Semantic Scholar
Ethanol sensitivity of NMDA receptor function in developing cerebellar granule neurons.
Sanjiv V. Bhave, L. Snell, B. Tabakoff, P. Hoffman
1999European Journal of Pharmacology28 citations
Semantic Scholar
Chronic Ethanol Exposure Attenuates the Anti‐Apoptotic Effect of NMDA in Cerebellar Granule Neurons
Sanjiv V. Bhave, L. Snell, B. Tabakoff, P. Hoffman
2000Journal of Neurochemistry27 citations
Semantic Scholar
The Effects of Ethanol on Neuronal and Glial Differentiation and Development
Toshikazu Saito, B. Tabakoff, P. Hoffman, K. Nixon +2 more
200526 citations
Semantic Scholar
Sex-Specific Role for Adenylyl Cyclase Type 7 in Alcohol Dependence
S. Desrivières, S. Pronko, A. Lourdusamy, F. Ducci +8 more
2011Biological Psychiatry25 citations Open access
Semantic Scholar
Gene array profiles of alcohol and aldehyde metabolizing enzymes in brains of C57BL/6 and DBA/2 mice.
Sanjiv V. Bhave, P. Hoffman, N. Lassen, V. Vasiliou +3 more
2006Alcoholism: Clinical and Experimental Research25 citations
Semantic Scholar
Role of protein kinase C in ethanol-induced activation of adenylyl cyclase.
M. Rabbani, E. Nelson, P. Hoffman, Boris Tabakoff
1999Alcoholism: Clinical and Experimental Research25 citations
Semantic Scholar
Gangliosides reduce the development of ethanol dependence without affecting ethanol tolerance.
L. Snell, G. Szabó, B. Tabakoff, P. Hoffman
1996Journal of Pharmacology and Experimental Therapeutics25 citations
Semantic Scholar
Networking in Biology: The Hybrid Rat Diversity Panel.
B. Tabakoff, Harry Smith, L. Vanderlinden, P. Hoffman +1 more
2019Methods in molecular biology24 citations
Semantic Scholar
Novel structure having antagonist actions at both the glycine site of the N-methyl-D-aspartate receptor and neuronal voltage-sensitive sodium channels: biochemical, electrophysiological, and behavioral characterization.
L. Snell, D. J. Claffey, J. A. Ruth, C. Valenzuela +10 more
2000Journal of Pharmacology and Experimental Therapeutics24 citations Open access
Semantic Scholar
Gene Expression in Animals with Different Acute Responses to Ethanol
P. Hoffman, B. Tabakoff
2005Addiction Biology23 citations
Semantic Scholar
Platelet adenylyl cyclase activity as a state or trait marker in alcohol dependence: results of the WHO/ISBRA Study on State and Trait Markers of Alcohol Use and Dependence.
P. Hoffman, J. Glanz, B. Tabakoff
2002Alcoholism: Clinical and Experimental Research23 citations
Semantic Scholar

Frequent co-authors

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Boris Tabakoff×5

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Masami Yoshimura×3

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Masami Yoshimura — researcher profile on SciRah