Ramreddy Tippana

Most-cited papers

1. Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36

   Michael C. Chen, Ramreddy Tippana, N. Demeshkina, Pierre Murat +3 more

   2018Nature290 citations Open access

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2. Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1 (Cas12a)

   Digvijay Singh, J. Mallon, A. Poddar, Yanbo Wang +4 more

   2018Proceedings of the National Academy of Sciences of the United States of America183 citations Open access

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3. G-quadruplex conformation and dynamics are determined by loop length and sequence

   Ramreddy Tippana, Weikun Xiao, S. Myong

   2014Nucleic Acids Research159 citations Open access

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4. Single-molecule imaging reveals a common mechanism shared by G-quadruplex–resolving helicases

   Ramreddy Tippana, Helen J. Hwang, Patricia L. Opresko, V. Bohr +1 more

   2016Proceedings of the National Academy of Sciences of the United States of America95 citations Open access

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5. RNA G-quadruplex is resolved by repetitive and ATP-dependent mechanism of DHX36

   Ramreddy Tippana, Michael C. Chen, N. Demeshkina, A. Ferré-D'Amaré +1 more

   2019Nature Communications77 citations Open access

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6. Sequencing by avidity enables high accuracy with low reagent consumption

   Sinan Arslan, Francisco J. Garcia, Minghao Guo, M. Kellinger +135 more

   2022bioRxiv71 citations Open access

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7. A guanine-flipping and sequestration mechanism for G-quadruplex unwinding by RecQ helicases

   A. F. Voter, Yupeng Qiu, Ramreddy Tippana, S. Myong +1 more

   2018Nature Communications56 citations Open access

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8. Antigenic Variation in Neisseria gonorrhoeae Occurs Independently of RecQ-Mediated Unwinding of the pilE G Quadruplex

   A. F. Voter, Melanie M. Callaghan, Ramreddy Tippana, S. Myong +2 more

   2019Journal of Bacteriology18 citations Open access

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9. Sequence-dependent mechanochemical coupling of helicase translocation and unwinding at single-nucleotide resolution

   Andrew H. Laszlo, Jonathan M. Craig, Momčilo Gavrilov, Ramreddy Tippana +12 more

   2022bioRxiv13 citations Open access

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10. High-Throughput Multiomics Profiling of Model Systems Using the AVITI24 Platform

    Tyler Lopez, Daniel Honigfort, Adeline Mah, Connor Thompson +68 more

    2025bioRxiv4 citations Open access

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11. Real-Time Detection of Cruciform Extrusion by Single-Molecule DNA Nanomanipulation

    Ramreddy Tippana

    20101 citations Open access

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12. Abstract 4950: Spatially resolved multiomic profiling of cancer tissue with DISS enables variant mapping across tissue landscape

    Vivian Dien, Tyler Lopez, Connor Thompson, Benjamin J. Krajacich +25 more

    2026Cancer Research0 citations

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13. Abstract 3702: Unraveling the mechanism of action for research of cancer therapies using AVITI24

    Vivian Dien, Connor Thompson, Daniel Honigfort, Tristin Rammel +8 more

    2025Cancer Research0 citations

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14. Unraveling Tyrosine-Kinase Inhibitor Resistance in NSCLC Cells via Same-cell Measurement of RNA, Protein, and Morphological Responses

    Vivian Dien, Connor Thompson, Tristin Rammel, Jaime Roquero +25 more

    2025bioRxiv0 citations Open access

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15. Nanopore Detects Compromise between Speed and Processivity of PcrA Helicase

    Momčilo Gavrilov, Ramreddy Tippana, Dmitriy G. Bobrovnikov, T. Ha

    2019Biophysical Journal0 citations Open access

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16. Analysis of Force Dependence of Translocation and Unwinding of Helicase PCRA using SPRNT

    Andrew H. Laszlo, Jonathan M. Craig, H. Brinkerhoff, Ian C. Nova +10 more

    20180 citations Open access

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17. G-Quadruplex DNA Folding and Dynamics within Duplex DNA

    Alex Kreig, Jacob Calvert, Ramreddy Tippana, S. Myong

    20140 citations Open access

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18. G-Quadruplex Folding Depends on its Loop Size and Sequence: Extreme Fast Folding Kinetics Observed in Human Telomere and its Isomer

    Ramreddy Tippana, Weikun Xiao, S. Myong

    20140 citations Open access

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19. Single Molecule Probing of the Human Tumor Suppression Transcription Initiation Machinery

    Ramreddy Tippana, Wei-Li Liu, R. A. Coleman

    20120 citations Open access

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