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I. Harvima · SciRah

Researcher profile · Semantic Scholar

I. Harvima

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I. Harvima — researcher profile on SciRah

h-index: 42
Works: 166
Citations: 7,591

Most-cited papers

New insights into the genetic etiology of Alzheimer’s disease and related dementias
C. Bellenguez, F. Küçükali, I. Jansen, L. Kleineidam +496 more
2022Nature Genetics1,984 citations Open access
Semantic Scholar
Mast cell-neural interactions contribute to pain and itch
K. Gupta, I. Harvima
2018Immunological Reviews274 citations Open access
Semantic Scholar
Efficacy of dietary hempseed oil in patients with atopic dermatitis
J. Callaway, U. Schwab, I. Harvima, P. Halonen +3 more
2005Journal of dermatological treatment (Print)172 citations
Semantic Scholar
Genetic architecture of human plasma lipidome and its link to cardiovascular disease
Rubina Tabassum, Joel T. Rämö, P. Ripatti, J. Koskela +255 more
2019Nature Communications167 citations Open access
Semantic Scholar
Mast Cells and Sensory Nerves Contribute to Neurogenic Inflammation and Pruritus in Chronic Skin Inflammation
H. Siiskonen, I. Harvima
2019Frontiers in Cellular Neuroscience159 citations Open access
Semantic Scholar
Mast cell CD30 ligand is upregulated in cutaneous inflammation and mediates degranulation-independent chemokine secretion.
M. Fischer, I. Harvima, R. Carvalho, C. Möller +3 more
2006Journal of Clinical Investigation142 citations Open access
Semantic Scholar
Molecular targets on mast cells and basophils for novel therapies.
I. Harvima, F. Levi-Schaffer, P. Dráber, Sheli Friedman +5 more
2014Journal of Allergy and Clinical Immunology138 citations Open access
Semantic Scholar
Is there a role for mast cells in psoriasis?
I. Harvima, G. Nilsson, Mireille-Maria Suttle, A. Naukkarinen
2008Archives of Dermatological Research137 citations Open access
Semantic Scholar
Mast cells as regulators of skin inflammation and immunity.
I. Harvima, G. Nilsson
2011Acta Dermato-Venereologica131 citations Open access
Semantic Scholar
SMOKING AND SKIN
A. Raitio, I. Harvima
200587 citations
Semantic Scholar
Low numbers of tryptase+ and chymase+ mast cells associated with reduced survival and advanced tumor stage in melanoma
H. Siiskonen, Mari Poukka, Andrey Bykachev, Kristiina Tyynelä-Korhonen +3 more
2015Melanoma research70 citations
Semantic Scholar
Role of mast cells and sensory nerves in skin inflammation.
I. Harvima, G. Nilsson, A. Naukkarinen
2010Giornale italiano di dermatologia e venereologia : organo ufficiale, Società italiana di dermatologia e sifilografia65 citations
Semantic Scholar
Expression of 15-lipoxygenase type-1 in human mast cells.
M. Gulliksson, Åsa Brunnström, Malin Johannesson, Linda Backman +5 more
2007Biochimica et Biophysica Acta65 citations
Semantic Scholar
Immunohistochemical analysis of sensory nerves and neuropeptides, and their contacts with mast cells in developing and mature psoriatic lesions
A. Naukkarinen, I. Harvima, Kari Paukkonen, M. Aalto +1 more
2004Archives of Dermatological Research65 citations
Semantic Scholar
Elevated levels of serum IL-5 are associated with an increased likelihood of major depressive disorder
Antti-Pekka Elomaa, L. Niskanen, K. Herzig, H. Viinamäki +6 more
2012BMC Psychiatry64 citations Open access
Semantic Scholar
Increased mast cell expression of PAR‐2 in skin inflammatory diseases and release of IL‐8 upon PAR‐2 activation
Ricardo Filipe da Silva Carvalho, G. Nilsson, I. Harvima
2010Experimental Dermatology64 citations
Semantic Scholar
The production of collagen and the activity of mast‐cell chymase increase in human skin after irradiation therapy
R. Riekki, I. Harvima, Arja Jukkola, J. Risteli +1 more
2004Experimental Dermatology62 citations
Semantic Scholar
Mast cell tryptase and chymase in developing and mature psoriatic lesions
I. Harvima, A. Naukkarinen, K. Paukkonen, R. Harvima +3 more
2004Archives of Dermatological Research56 citations
Semantic Scholar
Mast cell tryptase and chymase in chronic leg ulcers: chymase is potentially destructive to epithelium and is controlled by proteinase inhibitors
M. Huttunen, I. Harvima
2005British Journal of Dermatology52 citations
Semantic Scholar
Immunoperoxidase and enzyme-histochemical demonstration of human skin tryptase in cutaneous mast cells in normal and mastocytoma skin
I. Harvima, A. Naukkarinen, R. Harvima, J. Fräki
2004Archives of Dermatological Research51 citations
Semantic Scholar
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells
Erik L. Bao, Satish K. Nandakumar, Xiaotian Liao, A. Bick +335 more
2020Nature44 citations Open access
Semantic Scholar
Stress, the neuroendocrine system and mast cells: current understanding of their role in psoriasis
I. Harvima, G. Nilsson
2012Expert Review of Clinical Immunology44 citations
Semantic Scholar
OX40 ligand and OX40 are increased in atopic dermatitis lesions but do not correlate with clinical severity
Tiina Ilves, I. Harvima
2013Journal of the European Academy of Dermatology and Venereology43 citations
Semantic Scholar
The increase in tryptase‐ and chymase‐positive mast cells is associated with partial inactivation of chymase and increase in protease inhibitors in basal cell carcinoma
N. Diaconu, Renata Kaminska, A. Naukkarinen, R. Harvima +1 more
2007Journal of the European Academy of Dermatology and Venereology42 citations
Semantic Scholar
Experimentally induced psoriatic lesion associates with interleukin (IL)‐6 in mast cells and appearance of dermal cells expressing IL‐33 and IL‐6 receptor
Mireille-Maria Suttle, G. Nilsson, Erna Snellman, I. Harvima
2012Clinical and Experimental Immunology41 citations Open access
Semantic Scholar
Quantitative enzyme-histochemical analysis of tryptase- and chymase-containing mast cells in psoriatic skin
I. Harvima, A. Naukkarinen, R. Harvima, M. Aalto +2 more
2004Archives of Dermatological Research37 citations
Semantic Scholar
CC chemokine receptors CCR1 and CCR4 are expressed on airway mast cells in allergic asthma.
K. Amin, C. Janson, I. Harvima, P. Venge +1 more
2005Journal of Allergy and Clinical Immunology34 citations
Semantic Scholar
Enzyme- and immunohistochemical localization of mast cell tryptase in psoriatic skin
I. Harvima, A. Naukkarinen, R. Harvima, M. Horsmanheimo
2004Archives of Dermatological Research31 citations
Semantic Scholar
The BH3-Mimetic ABT-737 Induces Mast Cell Apoptosis In Vitro and In Vivo: Potential for Therapeutics
Mats Karlberg, M. Ekoff, David C. S. Huang, Paula K. Mustonen +2 more
2010Journal of Immunology28 citations Open access
Semantic Scholar
Increase in CD30 ligand/CD153 and TNF-α expressing mast cells in basal cell carcinoma
N. Diaconu, R. Kaminska, A. Naukkarinen, R. Harvima +2 more
2007Cancer Immunology and Immunotherapy27 citations Open access
Semantic Scholar
Accuracy and reliability of a hand‐held in vivo skin indentation device to assess skin elasticity
T. Virén, J. Iivarinen, J. Sarin, I. Harvima +1 more
2018International Journal of Cosmetic Science24 citations
Semantic Scholar
Mast cell proteinases and cytokines in skin inflammation
I. Harvima, L. Horsmanheimo, A. Naukkarinen, M. Horsmanheimo
2004Archives of Dermatological Research24 citations
Semantic Scholar
Anti-Apoptotic Bfl-1 Is the Major Effector in Activation-Induced Human Mast Cell Survival
M. Ekoff, K. Lyberg, M. Krajewska, M. Arvidsson +4 more
2012PLoS ONE22 citations Open access
Semantic Scholar
Effect of temporin A modifications on its cytotoxicity and antimicrobial activity
T. Mäntylä, Helena Sirola, Emilia Kansanen, T. Korjamo +5 more
2005Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS)22 citations
Semantic Scholar
Heparin modulates the growth and adherence and augments the growth‐inhibitory action of TNF‐α on cultured human keratinocytes
I. Harvima, K. Lappalainen, M. Hirvonen, M. Mättö +4 more
2004Journal of Cellular Biochemistry22 citations Open access
Semantic Scholar
Biochemical and histochemical evaluation of tryptase in various human tissues
I. Harvima, K. Karkola, R. Harvima, A. Naukkarinen +3 more
2004Archives of Dermatological Research22 citations
Semantic Scholar
Histamine, but not leukotriene C4, is an essential mediator in cold urticaria wheals.
P. Nuutinen, I. Harvima, L. Ackermann
2007Acta Dermato-Venereologica21 citations Open access
Semantic Scholar
Complement C3 is expressed by mast cells in cutaneous vasculitis and is degraded by chymase
Tiina Lipitsä, A. Naukkarinen, Joel Laitala, I. Harvima
2016Archives of Dermatological Research19 citations
Semantic Scholar
Decrease in chymase activity is associated with increase in IL-6 expression in mast cells in atopic dermatitis.
T. Ilves, I. Harvima
2015Acta Dermato-Venereologica19 citations Open access
Semantic Scholar
Mast cells express CYP27A1 and CYP27B1 in epithelial skin cancers and psoriasis
Antti P. Kaukinen, J. Pelkonen, I. Harvima
2015EJD. European journal of dermatology19 citations
Semantic Scholar
Induction of matrix metalloproteinase-9 in keratinocytes by histamine.
I. Harvima
2008Journal of Investigative Dermatology19 citations Open access
Semantic Scholar
Experimentally induced psoriatic lesions associate with rapid but transient decrease in interleukin-33 immunostaining in epidermis.
Mireille-Maria Suttle, Mattias Enoksson, A. Zoltowska, Madhumita Chatterjee +2 more
2015Acta Dermato-Venereologica18 citations Open access
Semantic Scholar
Juvenile‐onset neuronal ceroid lipofuscinosis with infantile CLN1 mutation and palmitoyl‐protein thioesterase deficiency
R. Kälviäinen, K. Eriksson, M. Losekoot, I. Sorri +7 more
2007European Journal of Neurology18 citations
Semantic Scholar
Mast cell chymase is present in uterine cervical carcinoma and it detaches viable and growing cervical squamous carcinoma cells from substratum in vitro
N. Diaconu, J. Rummukainen, A. Naukkarinen, M. Mättö +3 more
2011Archives of Dermatological Research17 citations
Semantic Scholar
Epidermal Expression of Filaggrin/Profilaggrin Is Decreased in Atopic Dermatitis: Reverse Association With Mast Cell Tryptase and IL-6 but Not With Clinical Severity
T. Ilves, V. Tiitu, Mireille-Maria Suttle, J. Saarinen +1 more
2015Dermatitis16 citations
Semantic Scholar
Increase in CD30 ligand/CD153 and TNF-alpha expressing mast cells in basal cell carcinoma.
N. Diaconu, R. Kaminska, A. Naukkarinen, R. Harvima +2 more
2007Cancer Immunology and Immunotherapy16 citations
Semantic Scholar
The prognostic and predictive role of tumor-infiltrating lymphocytes (FoxP3 + and CD8 +) and tumor-associated macrophages in early HER2 + breast cancer
M. Jääskeläinen, S. Tiainen, H. Siiskonen, M. Ahtiainen +8 more
2023Breast Cancer Research and Treatment15 citations Open access
Semantic Scholar
Hyaluronic acid inhibits the adherence and growth of monolayer keratinocytes but does not affect the growth of keratinocyte epithelium
I. Harvima, Hanna Heikura, M. Hyttinen, A. Naukkarinen
2006Archives of Dermatological Research15 citations
Semantic Scholar
Study of innervation, sensory neuropeptides, and serotonin in murine contact allergic skin.
H. El-Nour, L. Lundeberg, A. Boman, O. Beck +3 more
2005Immunopharmacology and immunotoxicology15 citations
Semantic Scholar
Regular use of vitamin D supplement is associated with fewer melanoma cases compared to non-use: a cross-sectional study in 498 adult subjects at risk of skin cancers
Emilia Kanasuo, H. Siiskonen, Salla Haimakainen, Jenni Komulainen +1 more
2022Melanoma research14 citations
Semantic Scholar

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A. Naukkarinen×17
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R. Harvima×9
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R. Harvima — researcher profile on SciRah
M. Horsmanheimo×6
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