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T. Shiraiwa · SciRah

Researcher profile · Semantic Scholar

T. Shiraiwa

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T. Shiraiwa — researcher profile on SciRah

h-index: 24
Works: 91
Citations: 2,122

Most-cited papers

Persistent expression of PDX-1 in the pancreas causes acinar-to-ductal metaplasia through Stat3 activation.
T. Miyatsuka, H. Kaneto, T. Shiraiwa, T. Matsuoka +11 more
2006Genes & Development176 citations Open access
Semantic Scholar
Safety and efficacy of oral semaglutide versus dulaglutide in Japanese patients with type 2 diabetes (PIONEER 10): an open-label, randomised, active-controlled, phase 3a trial.
D. Yabe, J. Nakamura, H. Kaneto, Srikanth Deenadayalan +39 more
2020The Lancet Diabetes and Endocrinology167 citations
Semantic Scholar
PDX-1 and MafA Play a Crucial Role in Pancreatic β-Cell Differentiation and Maintenance of Mature β-Cell Function
H. Kaneto, T. Miyatsuka, D. Kawamori, Kaoru Yamamoto +6 more
2008149 citations Open access
Semantic Scholar
Alogliptin, a Dipeptidyl Peptidase 4 Inhibitor, Prevents the Progression of Carotid Atherosclerosis in Patients With Type 2 Diabetes: The Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A)
T. Mita, N. Katakami, H. Yoshii, T. Onuma +12 more
2015Diabetes Care135 citations
Semantic Scholar
Sitagliptin Attenuates the Progression of Carotid Intima-Media Thickening in Insulin-Treated Patients With Type 2 Diabetes: The Sitagliptin Preventive Study of Intima-Media Thickness Evaluation (SPIKE)
T. Mita, N. Katakami, T. Shiraiwa, H. Yoshii +13 more
2016Diabetes Care133 citations
Semantic Scholar
Post-prandial hyperglycemia is an important predictor of the incidence of diabetic microangiopathy in Japanese type 2 diabetic patients.
T. Shiraiwa, H. Kaneto, T. Miyatsuka, K. Kato +8 more
2005Biochemical and Biophysical Research Communications - BBRC111 citations
Semantic Scholar
Postprandial hyperglycemia is a better predictor of the progression of diabetic retinopathy than HbA1c in Japanese type 2 diabetic patients.
T. Shiraiwa, H. Kaneto, T. Miyatsuka, K. Kato +8 more
2005Diabetes Care92 citations Open access
Semantic Scholar
Association of soluble epoxide hydrolase gene polymorphism with insulin resistance in type 2 diabetic patients.
K. Ohtoshi, H. Kaneto, K. Node, Yumiko Nakamura +3 more
2005Biochemical and Biophysical Research Communications - BBRC88 citations
Semantic Scholar
PDX-1 and MafA play a crucial role in pancreatic beta-cell differentiation and maintenance of mature beta-cell function.
H. Kaneto, T. Miyatsuka, D. Kawamori, Kaoru Yamamoto +6 more
2008Endocrine journal69 citations
Semantic Scholar
Comparative Effects of an Angiotensin II Receptor Blocker (ARB)/Diuretic vs. ARB/Calcium-Channel Blocker Combination on Uncontrolled Nocturnal Hypertension Evaluated by Information and Communication Technology-Based Nocturnal Home Blood Pressure Monitoring - The NOCTURNE Study.
K. Kario, N. Tomitani, Hiroshi Kanegae, H. Ishii +8 more
2017Circulation Journal57 citations Open access
Semantic Scholar
Combination therapy with liraglutide and insulin in Japanese patients with type 2 diabetes: A 36‐week, randomized, double‐blind, parallel‐group trial
Y. Seino, Shizuka Kaneko, S. Fukuda, T. Osonoi +4 more
2016Journal of Diabetes Investigation55 citations Open access
Semantic Scholar
Ameliorated pancreatic β cell dysfunction in type 2 diabetic patients treated with a sodium-glucose cotransporter 2 inhibitor ipragliflozin.
M. Takahara, T. Shiraiwa, T. Matsuoka, N. Katakami +1 more
2015Endocrine journal55 citations Open access
Semantic Scholar
Associations between continuous glucose monitoring-derived metrics and diabetic retinopathy and albuminuria in patients with type 2 diabetes
Satomi Wakasugi, T. Mita, N. Katakami, Y. Okada +9 more
2020BMJ Open Diabetes Research & Care49 citations Open access
Semantic Scholar
Crucial Role of PDX-1 in Pancreas Development, β-Cell Differentiation, and Induction of Surrogate β-Cells
H. Kaneto, T. Miyatsuka, T. Shiraiwa, Kaoru Yamamoto +3 more
200747 citations
Semantic Scholar
Tofogliflozin does not delay progression of carotid atherosclerosis in patients with type 2 diabetes: a prospective, randomized, open-label, parallel-group comparative study
N. Katakami, T. Mita, H. Yoshii, T. Shiraiwa +22 more
2020Cardiovascular Diabetology42 citations Open access
Semantic Scholar
Crucial role of PDX-1 in pancreas development, beta-cell differentiation, and induction of surrogate beta-cells.
H. Kaneto, T. Miyatsuka, T. Shiraiwa, Kaoru Yamamoto +3 more
2007Current Medicinal Chemistry38 citations
Semantic Scholar
Evaluation of health utility values for diabetic complications, treatment regimens, glycemic control and other subjective symptoms in diabetic patients using the EQ-5D-5L
M. Takahara, N. Katakami, T. Shiraiwa, K. Abe +8 more
2018Acta Diabetologica36 citations
Semantic Scholar
Effect of tofogliflozin on arterial stiffness in patients with type 2 diabetes: prespecified sub-analysis of the prospective, randomized, open-label, parallel-group comparative UTOPIA trial
N. Katakami, T. Mita, H. Yoshii, T. Shiraiwa +22 more
2021Cardiovascular Diabetology34 citations Open access
Semantic Scholar
Ptf1a and RBP-J cooperate in activating Pdx1 gene expression through binding to Area III.
T. Miyatsuka, T. Matsuoka, T. Shiraiwa, Tsunehiko Yamamoto +2 more
2007Biochemical and Biophysical Research Communications - BBRC32 citations
Semantic Scholar
Nighttime home blood pressure lowering effect of esaxerenone in patients with uncontrolled nocturnal hypertension: the EARLY-NH study
K. Kario, M. Nishizawa, Mitsutoshi Kato, H. Ishii +10 more
2023Hypertension Research29 citations Open access
Semantic Scholar
Associations of continuous glucose monitoring-assessed glucose variability with intima-media thickness and ultrasonic tissue characteristics of the carotid arteries: a cross-sectional analysis in patients with type 2 diabetes
Naohiro Taya, N. Katakami, T. Mita, Y. Okada +12 more
2021Cardiovascular Diabetology28 citations Open access
Semantic Scholar
Efficacy of sitagliptin on blood glucose fluctuation in Japanese type 2 diabetic patients with basal-supported oral therapy.
M. Takahara, T. Shiraiwa, H. Kaneto, N. Katakami +2 more
2012Endocrine journal26 citations Open access
Semantic Scholar
Beneficial effects of nateglinide on insulin resistance in type 2 diabetes.
Yoji Hazama, M. Matsuhisa, K. Ohtoshi, S. Gorogawa +8 more
2006Diabetes Research and Clinical Practice26 citations
Semantic Scholar
Continuous glucose monitoring-derived time in range and CV are associated with altered tissue characteristics of the carotid artery wall in people with type 2 diabetes
T. Mita, N. Katakami, Y. Okada, H. Yoshii +11 more
2023Diabetologia25 citations Open access
Semantic Scholar
Lifestyle changes and their impact on glycemic control and weight control in patients with diabetes during the coronavirus disease 2019 pandemic in Japan
M. Takahara, Hirotaka Watanabe, T. Shiraiwa, Y. Maeno +6 more
2021Journal of Diabetes Investigation25 citations Open access
Semantic Scholar
Applications of physical performance measures to routine diabetes care for frailty prevention concept: fundamental data with grip strength, gait speed, timed chair stand speed, standing balance, and knee extension strength
H. Yokoyama, T. Shiraiwa, M. Takahara, Masahiro Iwamoto +5 more
2020BMJ Open Diabetes Research & Care23 citations Open access
Semantic Scholar
Protocol of a Prospective Observational Study on the Relationship Between Glucose Fluctuation and Cardiovascular Events in Patients with Type 2 Diabetes
T. Mita, N. Katakami, Y. Okada, H. Yoshii +9 more
2019Diabetes Therapy22 citations Open access
Semantic Scholar
Liraglutide is effective and well tolerated in combination with an oral antidiabetic drug in Japanese patients with type 2 diabetes: A randomized, 52‐week, open‐label, parallel‐group trial
K. Kaku, A. Kiyosue, Y. Ono, T. Shiraiwa +4 more
2015Journal of Diabetes Investigation22 citations Open access
Semantic Scholar
Reproducibility and Validity of a Questionnaire Measuring Treatment Burden on Patients with Type 2 Diabetes: Diabetic Treatment Burden Questionnaire (DTBQ)
H. Ishii, Hiroki Shin, T. Tosaki, T. Haga +9 more
2018Diabetes Therapy21 citations Open access
Semantic Scholar
Rationale, design, and baseline characteristics of a trial for the prevention of diabetic atherosclerosis using a DPP-4 inhibitor: the Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A).
N. Katakami, T. Mita, H. Yoshii, T. Onuma +12 more
2013Journal of atherosclerosis and thrombosis20 citations Open access
Semantic Scholar
Rationale, design, and baseline characteristics of a clinical trial for prevention of atherosclerosis in patients with insulin-treated type 2 diabetes mellitus using DPP-4 inhibitor: the Sitagliptin Preventive study of Intima-media thickness Evaluation (SPIKE)
T. Mita, N. Katakami, T. Shiraiwa, H. Yoshii +13 more
2014Diabetology & Metabolic Syndrome19 citations Open access
Semantic Scholar
Efficacy of occasional self-monitoring of postprandial blood glucose levels in type 2 diabetic patients without insulin therapy.
T. Shiraiwa, M. Takahara, H. Kaneto, T. Miyatsuka +7 more
2010Diabetes Research and Clinical Practice19 citations
Semantic Scholar
Rationale, Design, and Baseline Characteristics of the Utopia Trial for Preventing Diabetic Atherosclerosis Using an SGLT2 Inhibitor: A Prospective, Randomized, Open-Label, Parallel-Group Comparative Study
N. Katakami, T. Mita, H. Yoshii, T. Shiraiwa +21 more
2017Diabetes Therapy18 citations Open access
Semantic Scholar
Dose-Dependent Effect of Sitagliptin on Carotid Atherosclerosis in Patients with Type 2 Diabetes Mellitus Receiving Insulin Treatment: A Post Hoc Analysis
T. Mita, N. Katakami, T. Shiraiwa, H. Yoshii +3 more
2017Diabetes Therapy14 citations Open access
Semantic Scholar
The impact of new-onset diabetes on arterial stiffness after renal transplantation.
K. Kato, M. Matsuhisa, N. Ichimaru, S. Takahara +10 more
2008Endocrine journal14 citations Open access
Semantic Scholar
Establishment of a non-invasive mouse reporter model for monitoring in vivo pdx-1 promoter activity.
T. Shiraiwa, H. Kaneto, T. Miyatsuka, K. Kato +7 more
2007Biochemical and Biophysical Research Communications - BBRC13 citations
Semantic Scholar
Association of obesity, diabetes, and physical frailty with dental and tongue-lip motor dysfunctions in patients with metabolic disease.
M. Takahara, T. Shiraiwa, Y. Maeno, Kaoru Yamamoto +6 more
2021Obesity Research and Clinical Practice12 citations
Semantic Scholar
Tofogliflozin long-term effects on atherosclerosis progression and major clinical parameters in patients with type 2 diabetes mellitus lacking a history of cardiovascular disease: a 2-year extension study of the UTOPIA trial
N. Katakami, T. Mita, H. Yoshii, T. Shiraiwa +78 more
2023Cardiovascular Diabetology11 citations Open access
Semantic Scholar
The Effect of Sitagliptin on the Regression of Carotid Intima-Media Thickening in Patients with Type 2 Diabetes Mellitus: A Post Hoc Analysis of the Sitagliptin Preventive Study of Intima-Media Thickness Evaluation
T. Mita, N. Katakami, T. Shiraiwa, H. Yoshii +3 more
2017International Journal of Endocrinology11 citations Open access
Semantic Scholar
Changes in carotid intima‐media thickening in patients with type 2 diabetes mellitus: Subanalysis of the Sitagliptin Preventive Study of Intima‐Media Thickness Evaluation
T. Mita, N. Katakami, T. Shiraiwa, H. Yoshii +3 more
2017Journal of Diabetes Investigation10 citations Open access
Semantic Scholar
Relationship between frequency of hypoglycemic episodes and changes in carotid atherosclerosis in insulin-treated patients with type 2 diabetes mellitus
T. Mita, N. Katakami, T. Shiraiwa, H. Yoshii +8 more
2017Scientific Reports10 citations Open access
Semantic Scholar
The Influence of Sitagliptin on Treatment-Related Quality of Life in Patients with Type 2 Diabetes Mellitus Receiving Insulin Treatment: A Prespecified Sub-Analysis
T. Mita, N. Katakami, T. Shiraiwa, H. Yoshii +5 more
2017Diabetes Therapy9 citations Open access
Semantic Scholar
Acute progression of severe insulin edema accompanied by pericardial and pleural effusion in a patient with type 2 diabetes.
S. Kawashima, H. Kaneto, K. Sakamoto, T. Yasuda +7 more
2008Diabetes Research and Clinical Practice9 citations
Semantic Scholar
Dramatic Improvement of Subcutaneous Insulin Resistance with Nafamostat Ointment Treatment
S. Kawashima, H. Kaneto, K. Sakamoto, Ikuko Honsho +7 more
2008Diabetes Care9 citations
Semantic Scholar
DAPagliflozin for the attenuation of albuminuria in Patients with hEaRt failure and type 2 diabetes (DAPPER study): a multicentre, randomised, open-label, parallel-group, standard treatment-controlled trial
F. Yoshihara, M. Imazu, Ichiro Sakuma, Y. Hiroi +27 more
2023EClinicalMedicine8 citations Open access
Semantic Scholar
Screening for a Decreased Masticatory Function by a Color-changeable Chewing Gum Test in Patients with Metabolic Disease
M. Takahara, T. Shiraiwa, Y. Maeno, Kaoru Yamamoto +5 more
2022Internal medicine8 citations Open access
Semantic Scholar
Long‐term (52‐week) efficacy and safety of dapagliflozin as an adjunct to insulin therapy in Japanese patients with type 1 diabetes: Subgroup analysis of the DEPICT‐2 study
E. Araki, C. Mathieu, T. Shiraiwa, H. Maeda +5 more
2021Diabetes, obesity and metabolism7 citations Open access
Semantic Scholar
Efficacy and safety of 10-mg azilsartan compared with 8-mg candesartan cilexetil in Japanese patients with hypertension: a randomized crossover non-inferiority trial
M. Takahara, T. Shiraiwa, Megumi Shindo, Akie Arai +5 more
2014Hypertension Research7 citations Open access
Semantic Scholar
Long-term efficacy and safety of early alogliptin initiation in subjects with type 2 diabetes: an extension of the SPEAD-A study
T. Mita, N. Katakami, H. Yoshii, Tomio Onuma +12 more
2023Scientific Reports6 citations Open access
Semantic Scholar
The Influence of Tofogliflozin on Treatment-Related Quality of Life in Patients with Type 2 Diabetes Mellitus
N. Katakami, T. Mita, H. Yoshii, T. Shiraiwa +99 more
2021Diabetes Therapy6 citations Open access
Semantic Scholar

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N. Katakami×30
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N. Katakami — researcher profile on SciRah
H. Kaneto×29
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H. Kaneto — researcher profile on SciRah
I. Shimomura×29
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T. Mita×20
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T. Mita — researcher profile on SciRah

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