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R. Ručman · SciRah

Researcher profile · Semantic Scholar

R. Ručman

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R. Ručman — researcher profile on SciRah

h-index: 29
Works: 83
Citations: 2,216

Most-cited papers

The influence of a novel pentadecapeptide, BPC 157, on N(G)-nitro-L-arginine methylester and L-arginine effects on stomach mucosa integrity and blood pressure.
P. Sikiric, S. Seiwerth, Ž. Grabarević, R. Ručman +20 more
1997European Journal of Pharmacology152 citations
Semantic Scholar
A new gastric juice peptide, BPC. An overview of the stomach-stress-organoprotection hypothesis and beneficial effects of BPC.
P. Sikiric, M. Petek, R. Ručman, S. Seiwerth +40 more
1993Journal of Physiology - Paris106 citations
Semantic Scholar
The beneficial effect of BPC 157, a 15 amino acid peptide BPC fragment, on gastric and duodenal lesions induced by restraint stress, cysteamine and 96% ethanol in rats. A comparative study with H2 receptor antagonists, dopamine promotors and gut peptides.
P. Sikiric, S. Seiwerth, Ž. Grabarević, M. Petek +12 more
1994Life Science105 citations
Semantic Scholar
Stable gastric pentadecapeptide BPC 157-NO-system relation.
P. Sikiric, S. Seiwerth, R. Ručman, B. Turković +15 more
2014Current pharmaceutical design97 citations
Semantic Scholar
BPC 157 and Standard Angiogenic Growth Factors. Gastrointestinal Tract Healing, Lessons from Tendon, Ligament, Muscle and Bone Healing.
S. Seiwerth, R. Ručman, B. Turković, M. Sever +17 more
2018Current pharmaceutical design84 citations
Semantic Scholar
Pentadecapeptide BPC 157 cream improves burn-wound healing and attenuates burn-gastric lesions in mice.
D. Mikus, P. Sikiric, S. Seiwerth, A. Petričević +18 more
2001Burns81 citations
Semantic Scholar
Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract.
P. Sikiric, S. Seiwerth, R. Ručman, B. Turković +10 more
2011Current pharmaceutical design71 citations
Semantic Scholar
Hepatoprotective effect of BPC 157, a 15-amino acid peptide, on liver lesions induced by either restraint stress or bile duct and hepatic artery ligation or CCl4 administration. A comparative study with dopamine agonists and somatostatin.
P. Sikiric, S. Seiwerth, Ž. Grabarević, R. Ručman +24 more
1993Life Science70 citations
Semantic Scholar
Osteogenic effect of a gastric pentadecapeptide, BPC-157, on the healing of segmental bone defect in rabbits: a comparison with bone marrow and autologous cortical bone implantation.
B. Šebečić, V. Nikolić, P. Sikiric, S. Seiwerth +9 more
1999Bone68 citations
Semantic Scholar
Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability.
R. Klicek, D. Kolenc, J. Šuran, D. Drmic +11 more
2013Journal of Physiology and Pharmacology63 citations
Semantic Scholar
Pentadecapeptide BPC 157 attenuates disturbances induced by neuroleptics: the effect on catalepsy and gastric ulcers in mice and rats.
N. Jelovac, P. Sikiric, R. Ručman, M. Petek +9 more
1999European Journal of Pharmacology63 citations
Semantic Scholar
BPC 157's effect on healing.
S. Seiwerth, P. Sikiric, Ž. Grabarević, I. Zoričić +16 more
1997Journal of Physiology - Paris60 citations
Semantic Scholar
Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications
P. Sikiric, S. Seiwerth, R. Ručman, D. Kolenc +16 more
2016Current Neuropharmacology59 citations Open access
Semantic Scholar
Corticosteroid-impairment of healing and gastric pentadecapeptide BPC-157 creams in burned mice.
P. Sikiric, S. Seiwerth, S. Miše, Mario Starešinić +8 more
2003Burns59 citations
Semantic Scholar
Novel Cytoprotective Mediator, Stable Gastric Pentadecapeptide BPC 157. Vascular Recruitment and Gastrointestinal Tract Healing.
P. Sikiric, R. Ručman, B. Turković, M. Sever +17 more
2018Current pharmaceutical design58 citations
Semantic Scholar
Pentadecapeptide BPC 157 positively affects both non-steroidal anti-inflammatory agent-induced gastrointestinal lesions and adjuvant arthritis in rats.
P. Sikiric, S. Seiwerth, Ž. Grabarević, R. Ručman +19 more
1997Journal of Physiology - Paris58 citations
Semantic Scholar
Focus on ulcerative colitis: stable gastric pentadecapeptide BPC 157.
P. Sikiric, S. Seiwerth, R. Ručman, B. Turković +12 more
2012Current Medicinal Chemistry57 citations
Semantic Scholar
A behavioural study of the effect of pentadecapeptide BPC 157 in Parkinson's disease models in mice and gastric lesions induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydrophyridine.
P. Sikiric, A. Marović, Wendy Matoz, T. Anić +20 more
1999Journal of Physiology - Paris55 citations
Semantic Scholar
BPC 157 and blood vessels.
S. Seiwerth, L. Brčić, L. Vuletić, D. Kolenc +6 more
2014Current pharmaceutical design54 citations
Semantic Scholar
Send Orders of Reprints at Reprints@benthamscience.org Toxicity by Nsaids. Counteraction by Stable Gastric Pentadecapeptide Bpc 157
P. Sikiric, S. Seiwerth, R. Ručman, B. Turković +15 more
52 citations
Semantic Scholar
The effect of pentadecapeptide BPC 157, H2-blockers, omeprazole and sucralfate on new vessels and new granulation tissue formation.
P. Sikiric, J. Šeparović, T. Anić, G. Buljat +21 more
1999Journal of Physiology - Paris50 citations
Semantic Scholar
Stress in Gastrointestinal Tract and Stable Gastric Pentadecapeptide BPC 157. Finally, do we have a Solution?
P. Sikiric, S. Seiwerth, R. Ručman, D. Drmic +11 more
2017Current pharmaceutical design46 citations
Semantic Scholar
Portal hypertension and liver lesions in chronically alcohol drinking rats prevented and reversed by stable gastric pentadecapeptide BPC 157 (PL-10, PLD-116), and propranolol, but not ranitidine.
I. Prkačin, J. Šeparović, Gorana Aralicia, D. Perović +18 more
2001Journal of Physiology - Paris46 citations
Semantic Scholar
Stable Gastric Pentadecapeptide BPC 157, Robert’s Stomach Cytoprotection/Adaptive Cytoprotection/Organoprotection, and Selye’s Stress Coping Response: Progress, Achievements, and the Future
P. Sikiric, K. Hahm, A. B. Blagaic, A. Tvrdeić +8 more
2019Gut and Liver45 citations Open access
Semantic Scholar
Beneficial effect of a novel pentadecapeptide BPC 157 on gastric lesions induced by restraint stress, ethanol, indomethacin, and capsaicin neurotoxicity
P. Sikiric, S. Seiwerth, Ž. Grabarević, R. Ručman +17 more
1996Digestive Diseases and Sciences43 citations
Semantic Scholar
Gastric pentadecapeptide BPC 157 effective against serotonin syndrome in rats.
Alenka Boban Blagaić, Vladimir Blagaić, M. Mirt, N. Jelovac +9 more
2005European Journal of Pharmacology42 citations
Semantic Scholar
Toxicity by NSAIDs. Counteraction by stable gastric pentadecapeptide BPC 157
P. Sikiric, S. Seiwerth, R. Ručman, B. Turković +15 more
201235 citations
Semantic Scholar
The influence of gastric pentadecapeptide BPC 157 on acute and chronic ethanol administration in mice. The effect of N(G)-nitro-L-arginine methyl ester and L-arginine.
Alenka Boban-Blagaić, Vladimir Blagaić, Ž. Romić, N. Jelovac +6 more
2006Medical Science Monitor33 citations
Semantic Scholar
The antidepressant effect of an antiulcer pentadecapeptide BPC 157 in Porsolt's test and chronic unpredictable stress in rats. A comparison with antidepressants.
P. Sikiric, Jadranka Šeparovic, G. Buljat, T. Anić +19 more
2000Journal of Physiology - Paris31 citations
Semantic Scholar
Pentadecapeptide BPC 157 attenuates chronic amphetamine-induced behavior disturbances.
P. Sikiric, N. Jelovac, A. Jelovac-Gjeldum, G. Dodig +19 more
2002Acta Pharmacologica Sinica28 citations
Semantic Scholar
Chronic cytoprotection: pentadecapeptide BPC 157, ranitidine and propranolol prevent, attenuate and reverse the gastric lesions appearance in chronic alcohol drinking rats.
I. Prkačin, G. Aralica, D. Perović, J. Šeparović +19 more
2001Journal of Physiology - Paris27 citations
Semantic Scholar
Cysteamine-colon and cysteamine-duodenum lesions in rats. Attenuation by gastric pentadecapeptide BPC 157, cimetidine, ranitidine, atropine, omeprazole, sulphasalazine and methylprednisolone.
P. Sikiric, S. Seiwerth, Ž. Grabarević, I. Balen +24 more
2001Journal of Physiology - Paris27 citations
Semantic Scholar
Therapy effect of antiulcer agents on new chronic cysteamine colon lesion in rat.
P. Sikiric, S. Seiwerth, G. Aralica, D. Perović +21 more
2001Journal of Physiology - Paris27 citations
Semantic Scholar
Gastric mucosal lesions induced by complete dopamine system failure in rats. The effects of dopamine agents, ranitidine, atropine, omeprazole and pentadecapeptide BPC 157.
P. Sikiric, J. Šeparović, G. Buljat, T. Anić +19 more
2000Journal of Physiology - Paris26 citations
Semantic Scholar
Long-lasting cytoprotection after pentadecapeptide BPC 157, ranitidine, sucralfate or cholestyramine application in reflux oesophagitis in rats.
P. Sikiric, Stipislav Jadrijević, S. Seiwerth, T. Šoša +22 more
1999Journal of Physiology - Paris23 citations
Semantic Scholar
Pentadecapeptide BPC 157, Cimetidine, Ranitidine, Bromocriptine, and Atropine Effect in Cysteamine Lesions in Totally Gastrectromized Rats (A Model for Cytoprotective Studies)
P. Sikiric, D. Mikus, S. Seiwerth, Ž. Grabarević +19 more
1997Digestive Diseases and Sciences22 citations
Semantic Scholar
Engineering recombinant Lactococcus lactis as a delivery vehicle for BPC-157 peptide with antioxidant activities
Katja Škrlec, R. Ručman, E. Jarc, P. Sikiric +5 more
2018Applied Microbiology and Biotechnology19 citations
Semantic Scholar
Lung lesions and anti-ulcer agents beneficial effect: anti-ulcer agents pentadecapeptide BPC 157, ranitidine, omeprazole and atropine ameliorate lung lesion in rats.
D. Stančić-Rokotov, Z. Slobodnjak, Josip Aralica, G. Aralica +15 more
2001Journal of Physiology - Paris19 citations
Semantic Scholar
Pentadecapeptide BPC 157 Beneficially Influences the Healing of Colon—Colon Anastomoses in Rats
I. Zoričić, P. Sikiric, S. Seiwerth, Ž. Grabarević +9 more
199719 citations
Semantic Scholar
Salutary and prophylactic effect of pentadecapeptide BPC 157 on acute pancreatitis and concomitant gastroduodenal lesions in rats
P. Sikiric, S. Seiwerth, Ž. Grabarević, R. Ručman +16 more
1996Digestive Diseases and Sciences19 citations
Semantic Scholar
Ethanol gastric lesion aggravated by lung injury in rat. Therapy effect of antiulcer agents.
D. Stančić-Rokotov, P. Sikiric, S. Seiwerth, Z. Slobodnjak +15 more
2001Journal of Physiology - Paris16 citations
Semantic Scholar
Dopamine agonists prevent duodenal ulcer relapse
P. Sikiric, I. Rotkvić, S. Mise, M. Petek +13 more
1991Digestive Diseases and Sciences16 citations
Semantic Scholar
Pentadecapeptide BPC 157 Interactions with Adrenergic and Dopaminergic Systems in Mucosal Protection in Stress
V. Jagić, B. Turković, I. Rotkvić, S. Miše +18 more
1997Digestive Diseases and Sciences14 citations
Semantic Scholar
The significance of the gastroprotective effect of body protection compound (BPC): modulation by different procedures.
P. Sikiric, M. Petek, R. Ručman, S. Seiwerth +6 more
1992Acta Physiologica Hungarica14 citations
Semantic Scholar
The effect of pentadecapeptide BPC 157 on inflammatory, non-inflammatory, direct and indirect pain and capsaicin neurotoxicity
P. Sikiric, K. Gyires, S. Seiwerth, Z. GrabarevlĆ +28 more
1993InflammoPharmacology12 citations
Semantic Scholar
Pentadecapeptide BPC 157 attenuates gastric lesions induced by alloxan in rats and mice.
M. Petek, P. Sikiric, T. Anić, G. Buljat +16 more
1999Journal of Physiology - Paris9 citations
Semantic Scholar
Efficacy of Dopaminergic Agents in Peptic Ulcer Healing and Relapse Prevention — Further Indication of the Importance of Stomach Dopamine in the Stress Organoprotection Concept
P. Sikiric, I. Rotkvic, S. Miše, S. Seiwerth +14 more
19957 citations
Semantic Scholar
A New Ergoline Derivative, LEK‐8829, as a Potential New Antipsychotic Drug
I. Krisch, R. Ručman, A. Lavrič, M. Ocvirk +1 more
19966 citations
Semantic Scholar
Hypothesis: stomach stress response, diagnostic and therapeutical value - a new approach in organoprotection
P. Sikiric, M. Petek, R. Ručman, I. Rotkvić +7 more
19915 citations
Semantic Scholar
Antiulcerogenic and anti-inflammatory effect of a new gastric juice peptide-body protection compound
P. Sikiric, M. Petek, I. Rotkvić, R. Ručman +12 more
19914 citations
Semantic Scholar

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S. Seiwerth×48
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S. Seiwerth — researcher profile on SciRah
P. Sikiric×45
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P. Sikiric — researcher profile on SciRah
B. Turković×36
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B. Turković — researcher profile on SciRah
M. Petek×35
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M. Petek — researcher profile on SciRah

×27

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S. Miše — researcher profile on SciRah

I. Rotkvić×26

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I. Rotkvić — researcher profile on SciRah

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V. Jagić — researcher profile on SciRah

Ž. Grabarević×22

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Ž. Grabarević — researcher profile on SciRah

J. Šeparović×21

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J. Šeparović — researcher profile on SciRah

D. Perović×20

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D. Perović — researcher profile on SciRah

I. Zoričić×18

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I. Zoričić — researcher profile on SciRah

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G. Aralica — researcher profile on SciRah