Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

D. F. Legler · SciRah

Researcher profile · Semantic Scholar

D. F. Legler

Share profile

D. F. Legler — researcher profile on SciRah

h-index: 46
Works: 148
Citations: 10K

Most-cited papers

Interstitial Dendritic Cell Guidance by Haptotactic Chemokine Gradients
Michèle Weber, R. Hauschild, Jan Schwarz, C. Moussion +5 more
2013Science561 citations Open access
Semantic Scholar
Prostaglandin E2 at new glance: novel insights in functional diversity offer therapeutic chances.
D. F. Legler, M. Bruckner, Edith Uetz-von Allmen, P. Krause
2010International Journal of Biochemistry and Cell Biology250 citations Open access
Semantic Scholar
Common and biased signaling pathways of the chemokine receptor CCR7 elicited by its ligands CCL19 and CCL21 in leukocytes
Mark A. Hauser, D. F. Legler
2016Journal of Leukocyte Biology181 citations
Semantic Scholar
Role of Mechanotransduction and Tension in T Cell Function
Jérémie Rossy, Julia M. Laufer, D. F. Legler
2018Frontiers in Immunology141 citations Open access
Semantic Scholar
Prostaglandin E(2) enhances T-cell proliferation by inducing the costimulatory molecules OX40L, CD70, and 4-1BBL on dendritic cells.
P. Krause, M. Bruckner, C. Uermösi, E. Singer +2 more
2009Blood113 citations Open access
Semantic Scholar
Inflammation-Induced CCR7 Oligomers Form Scaffolds to Integrate Distinct Signaling Pathways for Efficient Cell Migration.
Mark A. Hauser, Karin Schaeuble, I. Kindinger, D. Impellizzieri +4 more
2016Immunity103 citations Open access
Semantic Scholar
On the move: endocytic trafficking in cell migration
Tanja Maritzen, Hannah Schachtner, D. F. Legler
2015Cellular and Molecular Life Sciences98 citations Open access
Semantic Scholar
B cell zone reticular cell microenvironments shape CXCL13 gradient formation
J. Cosgrove, M. Novkovic, Stefan Albrecht, N. Pikor +27 more
2020Nature Communications85 citations Open access
Semantic Scholar
CCR7: roles in cancer cell dissemination, migration and metastasis formation.
D. F. Legler, Edith Uetz-von Allmen, Mark A. Hauser
2014International Journal of Biochemistry and Cell Biology79 citations Open access
Semantic Scholar
IL-4 receptor engagement in human neutrophils impairs their migration and extracellular trap formation.
D. Impellizzieri, Frederike Ridder, M. E. Raeber, C. Egholm +4 more
2019Journal of Allergy and Clinical Immunology78 citations Open access
Semantic Scholar
New insights in chemokine signaling
D. F. Legler, M. Thelen
2018F1000Research77 citations Open access
Semantic Scholar
Chemokines: Chemistry, Biochemistry and Biological Function.
D. F. Legler, M. Thelen
2016Chimia (Basel)75 citations Open access
Semantic Scholar
Distinct CCR7 glycosylation pattern shapes receptor signaling and endocytosis to modulate chemotactic responses
Mark A. Hauser, I. Kindinger, Julia M. Laufer, A. Spate +5 more
2016Journal of Leukocyte Biology73 citations
Semantic Scholar
Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4
P. Collins, M. McCully, Laura Martínez-Muñoz, César Santiago +14 more
2017The FASEB Journal68 citations Open access
Semantic Scholar
Keratinocytes control skin immune homeostasis through de novo–synthesized glucocorticoids
Truong San Phan, Leonhard Schink, J. Mann, Verena M. Merk +8 more
2021Science Advances52 citations Open access
Semantic Scholar
Ubiquitylation of the chemokine receptor CCR7 enables efficient receptor recycling and cell migration
Karin Schaeuble, Mark A. Hauser, A. Rippl, Roland Bruderer +3 more
2012Journal of Cell Science50 citations
Semantic Scholar
ACKR4 Recruits GRK3 Prior to β-Arrestins but Can Scavenge Chemokines in the Absence of β-Arrestins
Christoph Matti, A. Salnikov, Marc Artinger, G. D'Agostino +4 more
2020Frontiers in Immunology48 citations Open access
Semantic Scholar
Regulation of Sec16 levels and dynamics links proliferation and secretion
Kerstin D. Tillmann, Veronika Reiterer, F. Baschieri, Julia C Hoffmann +8 more
2015Journal of Cell Science46 citations Open access
Semantic Scholar
CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity
J. Gutjahr, Elisabeth Bayer, Xiao-Bin Yu, Julia M. Laufer +21 more
2020Haematologica42 citations Open access
Semantic Scholar
Beyond migration—Chemokines in lymphocyte priming, differentiation, and modulating effector functions
Julia M. Laufer, D. F. Legler
2018Journal of Leukocyte Biology42 citations Open access
Semantic Scholar
Cross-Talk Between TCR and CCR7 Signaling Sets a Temporal Threshold for Enhanced T Lymphocyte Migration
Karin Schaeuble, Mark A. Hauser, E. Singer, M. Groettrup +1 more
2011Journal of Immunology41 citations Open access
Semantic Scholar
Modulation of Chemokine Receptor Function by Cholesterol: New Prospects for Pharmacological Intervention
D. F. Legler, Christoph Matti, Julia M. Laufer, Barbara D Jakobs +3 more
2017Molecular Pharmacology36 citations Open access
Semantic Scholar
Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac Activation.
Julia M. Laufer, Mark A. Hauser, I. Kindinger, V. Purvanov +2 more
2019Cell Reports35 citations Open access
Semantic Scholar
CXCL14 Preferentially Synergizes With Homeostatic Chemokine Receptor Systems
A. Kouzeli, P. Collins, Mieke Metzemaekers, M. Meyrath +8 more
2020Frontiers in Immunology33 citations Open access
Semantic Scholar
β-Arrestin1 and β-Arrestin2 Are Required to Support the Activity of the CXCL12/HMGB1 Heterocomplex on CXCR4
G. D'Agostino, Marc Artinger, M. Locati, L. Perez +8 more
2020Frontiers in Immunology33 citations Open access
Semantic Scholar
Loss of GM130 in breast cancer cells and its effects on cell migration, invasion and polarity
F. Baschieri, Edith Uetz-von Allmen, D. F. Legler, H. Farhan
2015Cell Cycle33 citations Open access
Semantic Scholar
Dimeric form of CXCL12 binds to atypical chemokine receptor 1
J. Gutjahr, Kyler S. Crawford, Davin R. Jensen, P. Naik +7 more
2021Science Signaling32 citations Open access
Semantic Scholar
Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics.
Mona C Friess, I. Kritikos, Philipp Schineis, J. Medina-Sanchez +15 more
2022Cell Reports31 citations Open access
Semantic Scholar
CCL20 is a novel ligand for the scavenging atypical chemokine receptor 4
Christoph Matti, Giulia D'Uonnolo, Marc Artinger, Serena Melgrati +7 more
2020Journal of Leukocyte Biology31 citations Open access
Semantic Scholar
Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7
A. Jørgensen, O. Larsen, Edith Uetz-von Allmen, Michael Lückmann +5 more
2019Frontiers in Immunology31 citations Open access
Semantic Scholar
Chemokine axes in breast cancer: factors of the tumor microenvironment reshape the CCR7‐driven metastatic spread of luminal‐A breast tumors
Polina Weitzenfeld, Olga Kossover, Cindy Körner, Tsipi Meshel +4 more
2016Journal of Leukocyte Biology31 citations
Semantic Scholar
Converse regulation of CCR7‐driven human dendritic cell migration by prostaglandin E2 and liver X receptor activation
M. Bruckner, Denise Dickel, E. Singer, D. F. Legler
2012European Journal of Immunology31 citations Open access
Semantic Scholar
CCR7 Is Recruited to the Immunological Synapse, Acts as Co-stimulatory Molecule and Drives LFA-1 Clustering for Efficient T Cell Adhesion Through ZAP70
Julia M. Laufer, I. Kindinger, Marc Artinger, Andreas Pauli +1 more
2019Frontiers in Immunology30 citations Open access
Semantic Scholar
New pairings and deorphanization among the atypical chemokine receptor family — physiological and clinical relevance
M. Szpakowska, Giulia D'Uonnolo, R. Luís, Ana Alonso-Bartolomé +3 more
2023Frontiers in Immunology28 citations Open access
Semantic Scholar
A structure–activity relationship linking non-planar PCBs to functional deficits of neural crest cells: new roles for connexins
Johanna Nyffeler, Petra Chovancová, Xenia Dolde, Anna-Katharina Holzer +11 more
2017Archives of Toxicology28 citations Open access
Semantic Scholar
Fluorescently Tagged CCL19 and CCL21 to Monitor CCR7 and ACKR4 Functions
V. Purvanov, Christoph Matti, G. Samson, I. Kindinger +1 more
2018International Journal of Molecular Sciences27 citations Open access
Semantic Scholar
CCL19 with CCL21‐tail displays enhanced glycosaminoglycan binding with retained chemotactic potency in dendritic cells
A. Jørgensen, Pontian E. Adogamhe, Julia M. Laufer, D. F. Legler +3 more
2018Journal of Leukocyte Biology26 citations Open access
Semantic Scholar
Rapid increase in transferrin receptor recycling promotes adhesion during T cell activation
Pascal Rossatti, G. Redpath, Luca Ziegler, G. Samson +3 more
2022BMC Biology23 citations Open access
Semantic Scholar
Distinct modulation of chemokine expression patterns in human monocyte-derived dendritic cells by prostaglandin E(2).
M. Bruckner, Denise Dickel, E. Singer, D. F. Legler
2012Cellular Immunology21 citations Open access
Semantic Scholar
Medullary stromal cells synergize their production and capture of CCL21 for T-cell emigration from neonatal mouse thymus.
Kieran D. James, D. F. Legler, V. Purvanov, I. Ohigashi +5 more
2021Blood Advances20 citations Open access
Semantic Scholar
ZAP70 expression enhances chemokine‐driven chronic lymphocytic leukemia cell migration and arrest by valency regulation of integrins
Julia M. Laufer, Ruth Lyck, D. F. Legler
2018The FASEB Journal20 citations
Semantic Scholar
GPR182 is a broadly scavenging atypical chemokine receptor influencing T-independent immunity
Serena Melgrati, Oliver J. Gerken, Marc Artinger, Egle Radice +8 more
2023Frontiers in Immunology18 citations Open access
Semantic Scholar
A Versatile Toolkit for Semi-Automated Production of Fluorescent Chemokines to Study CCR7 Expression and Functions
Marc Artinger, Christoph Matti, Oliver J. Gerken, C. T. Veldkamp +1 more
2021International Journal of Molecular Sciences18 citations Open access
Semantic Scholar
The STEAP1262–270 peptide encapsulated into PLGA microspheres elicits strong cytotoxic T cell immunity in HLA‐A*0201 transgenic mice—A new approach to immunotherapy against prostate carcinoma
V. L. Herrmann, D. Wieland, D. F. Legler, V. Wittmann +1 more
2016The Prostate17 citations Open access
Semantic Scholar
International Union of Basic and Clinical Pharmacology. CXVIII. Update on the Nomenclature for Atypical Chemokine Receptors including ACKR5.
A. Chevigné, D. F. Legler, A. Rot, Silvano Sozzani +2 more
2024Pharmacological Reviews16 citations Open access
Semantic Scholar
Exocrine gland–resident memory CD8+ T cells use mechanosensing for tissue surveillance
N. Ruef, Jose Martínez Magdaleno, Xenia Ficht, V. Purvanov +11 more
2023Science immunology16 citations
Semantic Scholar
Delineating the interactions between the cannabinoid CB2 receptor and its regulatory effectors; β-arrestins and GPCR kinases
Monica Patel, Christoph Matti, N. Grimsey, D. F. Legler +3 more
2021British Journal of Pharmacology16 citations Open access
Semantic Scholar
Loss of Gadkin Affects Dendritic Cell Migration In Vitro
Hannah Schachtner, M. Weimershaus, V. Stache, Natalia Plewa +3 more
2015PLoS ONE14 citations Open access
Semantic Scholar
Distinct Fates of Chemokine and Surrogate Molecule Gradients: Consequences for CCR7-Guided Dendritic Cell Migration
Marc Artinger, Oliver J. Gerken, V. Purvanov, D. F. Legler
2022Frontiers in Immunology13 citations Open access
Semantic Scholar
Naive T lymphocytes chemotax long distance to CCL21 but not to a source of bioactive S1P
Nicolas Garcia-Seyda, S. Song, Valentine Seveau de Noray, Luc David-Broglio +8 more
2023iScience12 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

Julia M. Laufer×10
Invite
Julia M. Laufer — researcher profile on SciRah
M. Thelen×10
Invite
M. Thelen — researcher profile on SciRah
Marc Artinger×10
Invite
Marc Artinger — researcher profile on SciRah
V. Purvanov×9
Invite
V. Purvanov — researcher profile on SciRah

×8

Invite

Mark A. Hauser — researcher profile on SciRah

Christoph Matti×8

Invite

Christoph Matti — researcher profile on SciRah

I. Kindinger×7

Invite

I. Kindinger — researcher profile on SciRah

Edith Uetz-von Allmen×5

Invite

M. Bruckner — researcher profile on SciRah

Invite

E. Singer — researcher profile on SciRah

M. Groettrup×4

Invite

M. Groettrup — researcher profile on SciRah

M. Uguccioni×4

Invite

M. Uguccioni — researcher profile on SciRah