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A. Destro · SciRah

Researcher profile · Semantic Scholar

A. Destro

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A. Destro — researcher profile on SciRah

h-index: 35
Works: 84
Citations: 6,115

Most-cited papers

Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab
K. Yonesaka, K. Zejnullahu, I. Okamoto, T. Satoh +28 more
2011Science Translational Medicine674 citations Open access
Semantic Scholar
Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients.
F. Cappuzzo, A. Marchetti, M. Skokan, E. Rossi +14 more
2009Journal of Clinical Oncology561 citations Open access
Semantic Scholar
Diagnostic value of HSP70, glypican 3, and glutamine synthetase in hepatocellular nodules in cirrhosis
L. di Tommaso, Giada Franchi, Young Nyun Park, B. Fiamengo +9 more
2007Hepatology426 citations Open access
Semantic Scholar
A randomized study of lung cancer screening with spiral computed tomography: three-year results from the DANTE trial.
M. Infante, S. Cavuto, F. Lutman, G. Brambilla +16 more
2009American Journal of Respiratory and Critical Care Medicine407 citations
Semantic Scholar
Long-Term Follow-up Results of the DANTE Trial, a Randomized Study of Lung Cancer Screening with Spiral Computed Tomography.
M. Infante, S. Cavuto, F. Lutman, Eliseo Passera +20 more
2015American Journal of Respiratory and Critical Care Medicine325 citations
Semantic Scholar
MET increased gene copy number and primary resistance to gefitinib therapy in non-small-cell lung cancer patients.
F. Cappuzzo, P. Jänne, M. Skokan, G. Finocchiaro +11 more
2009Annals of Oncology316 citations Open access
Semantic Scholar
The application of markers (HSP70 GPC3 and GS) in liver biopsies is useful for detection of hepatocellular carcinoma.
L. di Tommaso, A. Destro, J. Seok, E. Balladore +10 more
2009Journal of Hepatology294 citations Open access
Semantic Scholar
EGFR FISH assay predicts for response to cetuximab in chemotherapy refractory colorectal cancer patients.
F. Cappuzzo, G. Finocchiaro, Elisa Rossi, P. Jänne +12 more
2008Annals of Oncology273 citations Open access
Semantic Scholar
Lung cancer screening with spiral CT: baseline results of the randomized DANTE trial.
M. Infante, F. Lutman, S. Cavuto, G. Brambilla +14 more
2008Lung Cancer222 citations
Semantic Scholar
The chemokine receptor CX3CR1 is involved in the neural tropism and malignant behavior of pancreatic ductal adenocarcinoma.
F. Marchesi, L. Piemonti, Giuseppe Fedele, A. Destro +15 more
2008Cancer Research195 citations Open access
Semantic Scholar
Primary resistance to cetuximab therapy in EGFR FISH-positive colorectal cancer patients
F. Cappuzzo, M. Varella-Garcia, G. Finocchiaro, M. Skokan +13 more
2008British Journal of Cancer188 citations Open access
Semantic Scholar
Cholangiocarcinoma stem-like subset shapes tumor-initiating niche by educating associated macrophages
C. Raggi, M. Correnti, A. Sica, J. Andersen +15 more
2016Journal of Hepatology167 citations Open access
Semantic Scholar
EGFR overexpression in malignant pleural mesothelioma. An immunohistochemical and molecular study with clinico-pathological correlations.
A. Destro, G. Ceresoli, M. Falleni, P. Zucali +9 more
2006Lung Cancer149 citations
Semantic Scholar
Telomere shortening and inactivation of cell cycle checkpoints characterize human hepatocarcinogenesis
R. Plentz, Y. N. Park, A. Lechel, Haeryoung Kim +8 more
2007Hepatology145 citations Open access
Semantic Scholar
Phase II Study of Everolimus in Patients With Thymoma and Thymic Carcinoma Previously Treated With Cisplatin-Based Chemotherapy.
P. Zucali, T. De Pas, G. Palmieri, A. Favaretto +20 more
2014Journal of Clinical Oncology143 citations
Semantic Scholar
Methylation framework of cell cycle gene inhibitors in cirrhosis and associated hepatocellular carcinoma
M. Roncalli, P. Bianchi, B. Bruni, L. Laghi +6 more
2002Hepatology122 citations Open access
Semantic Scholar
Modular Structure of the Human Lamin B2 Replicator
Sónia Paixão, I. Colaluca, M. Cubells, F. Peverali +6 more
2004Molecular and Cellular Biology108 citations Open access
Semantic Scholar
Role of cMET expression in non-small-cell lung cancer patients treated with EGFR tyrosine kinase inhibitors.
P. Zucali, M. G. Ruiz, Elisa Giovannetti, A. Destro +9 more
2008Annals of Oncology96 citations Open access
Semantic Scholar
MicroRNA profiling of hepatocarcinogenesis identifies C19MC cluster as a novel prognostic biomarker in hepatocellular carcinoma
C. Augello, V. Vaira, Luca Caruso, A. Destro +6 more
2012Liver international (Print)95 citations
Semantic Scholar
Thymidylate Synthase and Excision Repair Cross-Complementing Group-1 as Predictors of Responsiveness in Mesothelioma Patients Treated with Pemetrexed/Carboplatin
P. Zucali, E. Giovannetti, A. Destro, M. Mencoboni +13 more
2011Clinical Cancer Research95 citations Open access
Semantic Scholar
Diagnostic accuracy of clathrin heavy chain staining in a marker panel for the diagnosis of small hepatocellular carcinoma
L. di Tommaso, A. Destro, V. Fabbris, G. Spagnuolo +11 more
2011Hepatology88 citations Open access
Semantic Scholar
Genetic and epigenetic changes in primary metastatic and nonmetastatic colorectal cancer
E. Miranda, A. Destro, A. Malesci, E. Balladore +7 more
2006British Journal of Cancer88 citations Open access
Semantic Scholar
Specific patterns of PIWI-interacting small noncoding RNA expression in dysplastic liver nodules and hepatocellular carcinoma
F. Rizzo, A. Rinaldi, G. Marchese, Elena Coviello +12 more
2016OncoTarget74 citations Open access
Semantic Scholar
Human glioblastoma tumours and neural cancer stem cells express the chemokine CX3CL1 and its receptor CX3CR1.
M. Erreni, G. Solinas, P. Brescia, D. Osti +11 more
2010European Journal of Cancer73 citations
Semantic Scholar
Abl interconnects oncogenic Met and p53 core pathways in cancer cells
Alessandro Furlan, V. Stagni, A. Hussain, S. Richelme +6 more
2011Cell Death and Differentiation70 citations Open access
Semantic Scholar
Quantitative evaluation of RASSF1A methylation in the non-lesional, regenerative and neoplastic liver
S. Di Gioia, P. Bianchi, A. Destro, F. Grizzi +5 more
2006BMC Cancer68 citations Open access
Semantic Scholar
Toker cells of the breast. Morphological and immunohistochemical characterization of 40 cases.
L. di Tommaso, Giada Franchi, A. Destro, F. Broglia +3 more
2008Human Pathology65 citations
Semantic Scholar
K-ras and p16(INK4A)alterations in sputum of NSCLC patients and in heavy asymptomatic chronic smokers.
A. Destro, P. Bianchi, M. Alloisio, L. Laghi +10 more
2004Lung Cancer59 citations
Semantic Scholar
Molecular Alterations in Spontaneous Sputum of Cancer-Free Heavy Smokers: Results from a Large Screening Program
E. Baryshnikova, A. Destro, M. Infante, S. Cavuto +8 more
2008Clinical Cancer Research58 citations Open access
Semantic Scholar
The critical role of agrin in the hematopoietic stem cell niche.
Cristina Mazzon, A. Anselmo, J. Cibella, C. Soldani +7 more
2011Blood54 citations Open access
Semantic Scholar
Preclinical emergence of vandetanib as a potent antitumour agent in mesothelioma: molecular mechanisms underlying its synergistic interaction with pemetrexed and carboplatin
E. Giovannetti, P. Zucali, Y. Assaraf, L. Leon +9 more
2011British Journal of Cancer47 citations Open access
Semantic Scholar
Gene methylation in pleural mesothelioma: correlations with clinico-pathological features and patient's follow-up.
A. Destro, G. Ceresoli, E. Baryshnikova, I. Garassino +8 more
2008Lung Cancer43 citations
Semantic Scholar
Morphophenotypic changes in human multistep hepatocarcinogenesis with translational implications.
A. Sciarra, L. di Tommaso, M. Nakano, A. Destro +12 more
2016Journal of Hepatology41 citations Open access
Semantic Scholar
Molecular determinants of outcome in sorafenib-treated patients with hepatocellular carcinoma
N. Personeni, L. Rimassa, T. Pressiani, A. Destro +8 more
2013Journal of Cancer Research and Clinical Oncology40 citations Open access
Semantic Scholar
Genetic and epigenetic alterations in primary colorectal cancers and related lymph node and liver metastases
E. Miranda, P. Bianchi, A. Destro, E. Morenghi +4 more
2013Cancer39 citations Open access
Semantic Scholar
Detection of somatostatin receptor subtypes 2 and 5 by somatostatin receptor scintigraphy and immunohistochemistry: Clinical implications in the diagnostic and therapeutic management of gastroenteropancreatic neuroendocrine tumors
F. Sclafani, C. Carnaghi, L. di Tommaso, M. Rodari +6 more
2011Tumori25 citations
Semantic Scholar
Antitumor Activity of a Novel Fibroblast Growth Factor Receptor (FGFR) Inhibitor for Intrahepatic Cholangiocarcinoma.
C. Raggi, Karim Fiaccadori, M. Pastore, M. Correnti +22 more
2019American Journal of Pathology20 citations Open access
Semantic Scholar
p95HER2 Truncated Form in Resected Non-small Cell Lung Cancer
F. Cappuzzo, Y. Cho, A. Sacconi, G. Alí +8 more
2012Journal of Thoracic Oncology18 citations Open access
Semantic Scholar
Anatomic location of breast cancer micrometastasis in sentinel lymph node predicts axillary status.
L. di Tommaso, C. Arizzi, D. Rahal, A. Destro +9 more
2006Annals of Surgery17 citations
Semantic Scholar
Phenotypic and molecular changes in nodule‐in‐nodule hepatocellular carcinoma with pathogenetic implications
Noemi Rudini, C. Novello, A. Destro, E. Riboldi +5 more
2018Histopathology14 citations
Semantic Scholar
Emergence of KRAS-mutation in liver metastases after an anti-EGFR treatment in patient with colorectal cancer: Are we aware of the therapeutic impact of intratumor heterogeneity?
M. Baretti, N. Personeni, A. Destro, A. Santoro +1 more
2018Cancer Biology & Therapy13 citations Open access
Semantic Scholar
Pulmonary sarcomatoid carcinoma presenting both ALK rearrangement and PD-L1 high positivity
Federica D'Antonio, R. de Sanctis, I. Bolengo, A. Destro +3 more
2019Medicine12 citations Open access
Semantic Scholar
FACILITATE: A real-world, multicenter, prospective study investigating the utility of a rapid, fully automated real-time PCR assay versus local reference methods for detecting epidermal growth factor receptor variants in NSCLC
A. Behnke, A. Cayre, G. De Maglio, G. Giannini +14 more
2023Pathology and Oncology Research11 citations Open access
Semantic Scholar
Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature
R. Asselta, L. di Tommaso, M. Perrino, A. Destro +6 more
2021Thoracic Cancer11 citations Open access
Semantic Scholar
Immunohistohemical expression of the chemokine fractalkine and its receptor in the human brain cortex after severe traumatic brain injury and brain hemorrhage.
P. Gaetani, P. Pisano, G. Solinas, P. Colombo +6 more
2013Journal of Neurosurgical Sciences11 citations
Semantic Scholar
FOLFIRI and Cetuximab Every Second Week for First-Line Treatment of KRAS Wild-Type Metastatic Colorectal Cancer According to Phosphatase and Tensin Homolog Expression: A Phase II Study.
N. Personeni, L. Rimassa, C. Verusio, S. Barni +12 more
2015Clinical colorectal cancer10 citations
Semantic Scholar
Predictors of fulvestrant long-term benefit in hormone receptor-positive/HER2 negative advanced breast cancer
R. Torrisi, V. Vaira, L. Giordano, A. Destro +8 more
2022Scientific Reports9 citations Open access
Semantic Scholar
An exploratory biomarker study in metastatic tumors from colorectal cancer patients treated with bevacizumab
F. Sclafani, L. Rimassa, P. Colombo, A. Destro +8 more
2015International Journal of Biological Markers7 citations Open access
Semantic Scholar
9127 The role of thymidylate synthase (TS) and excision repair cross-complementing group 1 (ERCC1) immunohistochemical expression in malignant pleural mesothelioma patients treated with pemetrexed and carboplatin
P. Zucali, A. Destro, G. Ceresoli, L. Gianoncelli +6 more
20096 citations
Semantic Scholar
Telomere shortening and p21-checkpoint inactivation characterize multistep hepatocarcinogenesis in humans
R. Plentz, A. Lechel, Yn Park, Haeryoung Kim +8 more
20076 citations
Semantic Scholar

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