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M. Yurgelun · SciRah

Researcher profile · Semantic Scholar

M. Yurgelun

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M. Yurgelun — researcher profile on SciRah

h-index: 39
Works: 184
Citations: 6,927

Most-cited papers

Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
M. Daly, T. Pal, Michael P. Berry, S. Buys +30 more
2021The Journal of the National Comprehensive Cancer Network863 citations Open access
Semantic Scholar
NCCN Guidelines® Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 2.2024.
Mary B. Daly, Tuya Pal, Kara N. Maxwell, Jane Churpek +36 more
2023The Journal of the National Comprehensive Cancer Network296 citations Open access
Semantic Scholar
Combined PD-1, BRAF and MEK inhibition in BRAFV600E colorectal cancer: a phase 2 trial
Jun Tian, Jonathan H. Chen, S. Chao, K. Pelka +41 more
2023Nature Medicine185 citations Open access
Semantic Scholar
NCCN Guidelines® Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 1.2021.
J. Weiss, Samir Gupta, C. Burke, L. Axell +30 more
2021The Journal of the National Comprehensive Cancer Network166 citations
Semantic Scholar
Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines
Martina Cavestro Giulia, A. Mannucci, F. Balaguer, H. Hampel +62 more
2022Clinical Gastroenterology and Hepatology140 citations Open access
Semantic Scholar
A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study
E. Bancroft, E. Page, M. Brook, Sarah Thomas +314 more
2021The Lancet Oncology77 citations Open access
Semantic Scholar
Adipose tissue and skeletal muscle wasting precede clinical diagnosis of pancreatic cancer
A. Babic, M. Rosenthal, T. Sundaresan, Natalia Khalaf +21 more
2023Nature Communications65 citations Open access
Semantic Scholar
Prevalence of Mismatch-Repair Deficiency in Rectal Adenocarcinomas.
D. Papke, M. Yurgelun, A. Noffsinger, K. Turner +2 more
2022New England Journal of Medicine61 citations Open access
Semantic Scholar
Aberrant cell state plasticity mediated by developmental reprogramming precedes colorectal cancer initiation
Dr.Pronay Bala, J. Rennhack, Daulet Aitymbayev, Clare X Morris +9 more
2022bioRxiv55 citations Open access
Semantic Scholar
NCCN Guidelines® Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, Pancreatic, and Prostate, Version 2.2026.
Heather H. Cheng, V. Giri, Michael Goggins, M. Yurgelun +37 more
2026The Journal of the National Comprehensive Cancer Network33 citations
Semantic Scholar
Oncogenic drivers and therapeutic vulnerabilities in KRAS wild-type pancreatic cancer
Harshabad Singh, R. Keller, Kevin S. Kapner, Julien Dilly +28 more
2023Clinical Cancer Research33 citations Open access
Semantic Scholar
Blockade of IL-1β and PD-1 with combination chemotherapy reduces systemic myeloid suppression in metastatic pancreatic cancer with heterogeneous effects in the tumor
Paul E. Oberstein, A. D. Costa, Emily A. Kawaler, V. Cardot-Ruffino +37 more
2024Cancer immunology research30 citations Open access
Semantic Scholar
Risk assessment and genetic counseling for Lynch syndrome – Practice resource of the National Society of Genetic Counselors and the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer
S. Holter, M. Hall, H. Hampel, K. Jasperson +8 more
2022Journal of Genetic Counseling29 citations Open access
Semantic Scholar
Implementing Systematic Genetic Counseling and Multigene Germline Testing for Individuals With Pancreatic Cancer.
A. Chittenden, S. Haraldsdottir, C. Ukaegbu, Meghan Underhill-Blazey +7 more
2021JCO Oncology Practice27 citations Open access
Semantic Scholar
Point/Counterpoint: Is It Time for Universal Germline Genetic Testing for all GI Cancers?
H. Hampel, M. Yurgelun
2022Journal of Clinical Oncology25 citations
Semantic Scholar
Clinical outcomes and ctDNA correlates for CAPOX BETR: a phase II trial of capecitabine, oxaliplatin, bevacizumab, trastuzumab in previously untreated advanced HER2+ gastroesophageal adenocarcinoma
Harshabad Singh, Kristen E. Lowder, Kevin S. Kapner, R. Kelly +21 more
2024Nature Communications22 citations
Semantic Scholar
G-CSF rescue of FOLFIRINOX-induced neutropenia leads to systemic immune suppression in mice and humans
V. Cardot-Ruffino, Naima Bollenrucher, L. Delius, S. J. Wang +20 more
2023Journal for ImmunoTherapy of Cancer20 citations Open access
Semantic Scholar
A Randomized Trial of Two Remote Healthcare Delivery Models on the Uptake of Genetic Testing and Impact on Patient-Reported Psychological Outcomes in Families With Pancreatic Cancer: The Genetic Education, Risk Assessment, and Testing (GENERATE) Study
N. Rodriguez, C. S. Furniss, M. Yurgelun, C. Ukaegbu +24 more
2024Gastroenterology19 citations Open access
Semantic Scholar
Lynch Syndrome-Associated Cancers Beyond Colorectal Cancer.
Leah H. Biller, Siobhan A. Creedon, Margaret R Klehm, M. Yurgelun
2022Gastrointestinal Endoscopy Clinics of North America19 citations
Semantic Scholar
Novel Models of Genetic Education and Testing for Pancreatic Cancer Interception: Preliminary Results from the GENERATE Study
C. S. Furniss, M. Yurgelun, C. Ukaegbu, P. Constantinou +24 more
2021Cancer Prevention Research18 citations Open access
Semantic Scholar
Managing gastric cancer risk in lynch syndrome: controversies and recommendations
C. Boland, M. Yurgelun, Kathryn A. Mraz, P. Boland
2021Familial Cancer17 citations Open access
Semantic Scholar
Clinical Implications of Pathogenic Germline Variants in Small Intestine Neuroendocrine Tumors (SI-NETs)
K. Perez, M. Kulke, A. Chittenden, C. Ukaegbu +13 more
2021JCO Precision Oncology14 citations
Semantic Scholar
Identification and Management of Pathogenic Variants in BRCA1, BRCA2, and PALB2 in a Tumor-Only Genomic Testing Program
B. Bychkovsky, Tian-Yu Li, Jilliane Sotelo, N. Tayob +19 more
2022Clinical Cancer Research13 citations Open access
Semantic Scholar
Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders
B. Huffman, Harshabad Singh, Lestat R. Ali, N. Horick +34 more
2024Journal for ImmunoTherapy of Cancer12 citations Open access
Semantic Scholar
An updated counseling framework for moderate-penetrance colorectal cancer susceptibility genes.
K. Breen, B. Katona, Amanda Catchings, Megha Ranganathan +4 more
2022Genetics in Medicine12 citations Open access
Semantic Scholar
Gastric Polyposis and Cancer in Western Patients With Familial Adenomatous Polyposis: Epidemiology, Detection, and Management.
A. Aelvoet, E. Dekker, Michael Cruise, William M. Grady +9 more
2025The Journal of the National Comprehensive Cancer Network11 citations
Semantic Scholar
An integrated somatic and germline approach to aid interpretation of germline variants of uncertain significance in cancer susceptibility genes
Alison Schwartz, Danielle K. Manning, Diane R. Koeller, A. Chittenden +11 more
2022Frontiers in Oncology11 citations Open access
Semantic Scholar
Familial Burden and Other Clinical Factors Associated With Various Types of Cancer in Individuals With Lynch Syndrome
Leah H. Biller, M. Horiguchi, H. Uno, C. Ukaegbu +2 more
2021Gastroenterology11 citations Open access
Semantic Scholar
Phase Ib and Expansion Study of Gemcitabine, Nab-Paclitaxel, and Ficlatuzumab in Patients With Metastatic Pancreatic Cancer
Kimberly Perez, Anna M. Chiarella, J. Cleary, N. Horick +22 more
2023The Oncologist8 citations Open access
Semantic Scholar
Development and Validation of the PREMMplus Model for Multigene Hereditary Cancer Risk Assessment
M. Yurgelun, H. Uno, C. S. Furniss, C. Ukaegbu +6 more
2022Journal of Clinical Oncology8 citations Open access
Semantic Scholar
Advancing the Evaluation and Management of CDH1-Associated Gastric Cancer.
B. A. Lerner, Samir Gupta, Carol A. Burke, S. Kupfer +12 more
2025The Journal of the National Comprehensive Cancer Network7 citations
Semantic Scholar
Open-Label, Phase II Trial of Extracellular Regulated Kinase Inhibition Alone and in Combination With Autophagy Inhibition in Patients With Metastatic Pancreatic Cancer
R. Surana, Micaela Morgado, Ashwin S. Somasundaram, B. Bockorny +40 more
2025JCO Precision Oncology7 citations Open access
Semantic Scholar
Programmatic Precision Oncology Decision Support for Patients With Gastrointestinal Cancer
R. Keller, T. Mazor, L. Sholl, Andrew J. Aguirre +39 more
2023JCO Precision Oncology7 citations Open access
Semantic Scholar
MyLynch: A Patient-Facing Clinical Decision Support Tool for Genetically-Guided Personalized Medicine in Lynch Syndrome
Stephen Knapp, Anna Revette, Meghan Underhill-Blazey, J. Stopfer +11 more
2023Cancers7 citations Open access
Semantic Scholar
The Evolving Paradigm of Germline Testing in Pancreatic Ductal Adenocarcinoma and Implications for Clinical Practice.
C. Mohindroo, A. De Jesus-Acosta, M. Yurgelun, A. Maitra +2 more
2022Surgical Pathology Clinics7 citations Open access
Semantic Scholar
Physical activity in older adults with metastatic gastrointestinal cancer: a pilot and feasibility study
Justin C. Brown, E. Brighton, Nancy Campbell, N. McCleary +8 more
2022BMJ Open Sport & Exercise Medicine6 citations Open access
Semantic Scholar
Building on More Than 20 Years of Progress in Pancreatic Cancer Surveillance for High-Risk Individuals.
M. Yurgelun
2022Journal of Clinical Oncology6 citations
Semantic Scholar
A phase II study of ramucirumab and somatostatin analog therapy in patients with advanced neuroendocrine tumors
Kimberley J. Perez, M. Kulke, Hui Zheng, Jill N. Allen +13 more
2025The Oncologist5 citations Open access
Semantic Scholar
PREMM5 Distinguishes Sporadic from Lynch Syndrome-Associated MMR-Deficient/MSI-High Colorectal Cancer
R. Sandoval, M. Horiguchi, C. Ukaegbu, C. S. Furniss +3 more
2023Familial Cancer5 citations
Semantic Scholar
Clinical Factors Associated with Skin Neoplasms in Individuals with Lynch Syndrome in a Longitudinal Observational Cohort
Connie S. Zhong, M. Horiguchi, H. Uno, C. Ukaegbu +5 more
2023Journal of American Academy of Dermatology5 citations Open access
Semantic Scholar
Surveillance imaging in individuals at high-risk for pancreatic cancer: Not a ceiling, but rather a floor upon which to build.
M. Rosenthal, B. Wolpin, M. Yurgelun
2021Gastroenterology5 citations
Semantic Scholar
A Case of Microsatellite Instability-High Colon Cancer in a Young Woman With Familial Adenomatous Polyposis.
Steven M. Blum, W. Jeck, L. Kipnis, R. Bleday +2 more
2021The Journal of the National Comprehensive Cancer Network4 citations
Semantic Scholar
Clinical and fertility outcomes in lynch syndrome patients with endometrial carcinoma or endometrial Intraepthelial neoplasia treated with fertility sparing management
Hadley Reid, A. Young, Sophia H. Yin, Isabela Covelli Velez +6 more
2025Gynecologic Oncology Reports3 citations Open access
Semantic Scholar
Abstract A001: An open label, phase II trial of ERK inhibition alone and in combination with autophagy inhibition in patients with metastatic cancreatic cancer
R. Surana, Hui Zheng, Jun-Ning Wang, Micaela Morgado +31 more
2024Cancer Research3 citations
Semantic Scholar
Prevalence and Distribution of Unexpected Actionable Germline Pathogenic Variants Identified on Broad-Based Multigene Panel Testing Among Patients With Cancer
Kara K. Landry, M. Desarno, L. Kipnis, Farid Barquet Ramos +10 more
2024JCO Precision Oncology3 citations
Semantic Scholar
Cetuximab and Irinotecan With or Without Bevacizumab in Refractory Metastatic Colorectal Cancer: BOND-3, an ACCRU Network Randomized Clinical Trial
M. Lipsyc-Sharf, F. Ou, M. Yurgelun, D. Rubinson +14 more
2022The Oncologist3 citations Open access
Semantic Scholar
Durable clinical benefit from PARP inhibition in a platinum-sensitive, BRCA2-mutated pancreatic cancer patient after earlier progression on placebo treatment on the POLO trial: a case report.
D. Rubinson, B. Wolpin, I. S. Warsofsky, D. Ryan +8 more
2021Journal of Gastrointestinal Oncology3 citations Open access
Semantic Scholar
Lynch syndrome integrative epidemiology and genetics (LINEAGE): rationale for cohort design
Swati G. Patel, H. Loomans-Kropp, Z. Foda, B. Katona +74 more
2026Familial Cancer2 citations
Semantic Scholar
Neoplasia detection via colonic surveillance among young individuals with MSH6 and PMS2-associated Lynch Syndrome.
Alicia J. Latham, Ying L. Liu, Gil-Juárez Constantino, Matilde Borio +14 more
2025American Journal of Gastroenterology2 citations
Semantic Scholar
Developmental reprogramming mediates aberrant cell state plasticity in colorectal cancer initiation
Dr.Pronay Bala, J. Rennhack, C. Morris, Daulet Aitymbayev +9 more
20222 citations
Semantic Scholar

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