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K. Alkharfy · SciRah

Researcher profile · Semantic Scholar

K. Alkharfy

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K. Alkharfy — researcher profile on SciRah

h-index: 48
Works: 236
Citations: 7,409

Most-cited papers

Gastroprotective Effect of Sinapic Acid on Ethanol-Induced Gastric Ulcers in Rats: Involvement of Nrf2/HO-1 and NF-κB Signaling and Antiapoptotic Role
M. Raish, Mudassar Shahid, Yousef A. Bin Jardan, M. A. Ansari +5 more
2021Frontiers in Pharmacology156 citations Open access
Semantic Scholar
Momordica charantia polysaccharides ameliorate oxidative stress, inflammation, and apoptosis in ethanol-induced gastritis in mucosa through NF-kB signaling pathway inhibition.
M. Raish, Ajaz Ahmad, M. A. Ansari, K. Alkharfy +5 more
2018International Journal of Biological Macromolecules149 citations
Semantic Scholar
Application of Box-Behnken design for ultrasonic-assisted extraction of polysaccharides from Paeonia emodi.
Ajaz Ahmad, K. Alkharfy, T. Wani, M. Raish
2015International Journal of Biological Macromolecules125 citations
Semantic Scholar
Pharmacokinetic plasma behaviors of intravenous and oral bioavailability of thymoquinone in a rabbit model
K. Alkharfy, Ajaz Ahmad, R. M. A. Khan, Waleed M. Al-Shagha
2015European journal of drug metabolism and pharmacokinetics114 citations
Semantic Scholar
Sinapic acid ameliorate cadmium-induced nephrotoxicity: In vivo possible involvement of oxidative stress, apoptosis, and inflammation via NF-κB downregulation.
M. A. Ansari, M. Raish, Ajaz Ahmad, K. Alkharfy +4 more
2017Environmental Toxicology and Pharmacology108 citations
Semantic Scholar
Oral bioavailability enhancement and hepatoprotective effects of thymoquinone by self-nanoemulsifying drug delivery system.
M. Kalam, M. Raish, Ajaz Ahmed, K. Alkharfy +5 more
2017Materials Science and Engineering C: Materials for Biological Applications84 citations
Semantic Scholar
Hepatoprotective activity of Lepidium sativum seeds against D-galactosamine/lipopolysaccharide induced hepatotoxicity in animal model
M. Raish, Ajaz Ahmad, K. Alkharfy, S. R. Ahamad +4 more
2016BMC Complementary and Alternative Medicine82 citations Open access
Semantic Scholar
Momordica charantia polysaccharides mitigate the progression of STZ induced diabetic nephropathy in rats.
M. Raish, Ajaz Ahmad, Basit L Jan, K. Alkharfy +4 more
2016International Journal of Biological Macromolecules81 citations
Semantic Scholar
Sinapic Acid Ameliorates Oxidative Stress, Inflammation, and Apoptosis in Acute Doxorubicin-Induced Cardiotoxicity via the NF-κB-Mediated Pathway
Yousef A. Bin Jardan, M. A. Ansari, Mohammad Raish, K. Alkharfy +5 more
2020BioMed Research International80 citations Open access
Semantic Scholar
Sinapic Acid Ameliorates Acetic Acid-Induced Ulcerative Colitis in Rats by Suppressing Inflammation, Oxidative Stress, and Apoptosis
Mudassar Shahid, Mohammad Raish, Ajaz Ahmad, Yousef A. Bin Jardan +5 more
2022Molecules77 citations Open access
Semantic Scholar
Capparis spinosa L.: A plant with high potential for development of functional foods and nutraceuticals/pharmaceuticals
M. Mohamed, G. Muhammad, M. Hussain, G. Zengin +3 more
201663 citations Open access
Semantic Scholar
Does visceral adiposity index signify early metabolic risk in children and adolescents?: Association with insulin resistance, adipokines, and subclinical inflammation
N. Al-Daghri, O. Al-attas, M. Alokail, K. Alkharfy +9 more
2014Pediatric Research60 citations
Semantic Scholar
Sinapic acid ameliorates cardiac dysfunction and cardiomyopathy by modulating NF-κB and Nrf2/HO-1 signaling pathways in streptozocin induced diabetic rats.
M. Raish, Ajaz Ahmad, Yousef A. Bin Jardan, Mudassar Shahid +5 more
2021Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie56 citations Open access
Semantic Scholar
CHEMICAL COMPOSITION AND BIOLOGICAL ACTIVITIES OF LEAVES OF ZIZIPHUS MAURITIANA L . NATIVE TO PAKISTAN
A. Ashraf, R. Sarfraz, F. Anwar, S. Shahid +1 more
201556 citations
Semantic Scholar
An alternative approach to minimize the risk of coronavirus (Covid-19) and similar infections.
Ajaz Ahmad, M. Rehman, K. Alkharfy
2020European Review for Medical and Pharmacological Sciences54 citations
Semantic Scholar
Beetroot juice alleviates isoproterenol-induced myocardial damage by reducing oxidative stress, inflammation, and apoptosis in rats
M. Raish, Ajaz Ahmad, M. A. Ansari, K. Alkharfy +5 more
20193 Biotech53 citations Open access
Semantic Scholar
Directly compressed rosuvastatin calcium tablets that offer hydrotropic and micellar solubilization for improved dissolution rate and extent of drug release
Sharonia Butt, S. M. Hasan, M. M. Hassan, K. Alkharfy +1 more
2019Saudi Pharmaceutical Journal48 citations Open access
Semantic Scholar
Solubility, solubility parameters and solution thermodynamics of thymoquinone in different mono solvents
Ajaz Ahmad, M. Raish, K. Alkharfy, I. Alsarra +4 more
2018Journal of Molecular Liquids47 citations
Semantic Scholar
Myricetin (3,3′,4′,5,5′,7-Hexahydroxyflavone) Prevents 5-Fluorouracil-Induced Cardiotoxicity
A. Arafah, M. Rehman, Ajaz Ahmad, K. Alkharfy +3 more
2022ACS Omega46 citations Open access
Semantic Scholar
Gender-dependent associations between socioeconomic status and metabolic syndrome: a cross-sectional study in the adult Saudi population
N. Al-Daghri, K. Alkharfy, O. Al-attas, N. Khan +5 more
2014BMC Cardiovascular Disorders45 citations Open access
Semantic Scholar
Saudi Arabia, pharmacists and COVID-19 pandemic
Ajaz Ahmad, K. Alkharfy, Ziyad Alrabiah, A. Alhossan
2020Journal of Pharmaceutical Policy and Practice44 citations Open access
Semantic Scholar
Thymoquinone treatment modulates the Nrf2/HO-1 signaling pathway and abrogates the inflammatory response in an animal model of lung fibrosis
Ajaz Ahmad, K. Alkharfy, Basit L Jan, A. Ahad +3 more
2020Experimental Lung Research41 citations
Semantic Scholar
Development of Liposomal Formulation for Delivering Anticancer Drug to Breast Cancer Stem-Cell-Like Cells and its Pharmacokinetics in an Animal Model.
Ajaz Ahmad, S. Mondal, D. Mukhopadhyay, Rajkumar Banerjee +1 more
2016Molecular Pharmaceutics41 citations Open access
Semantic Scholar
Chemo-geographical Variations in the Composition of Volatiles and the Biological Attributes of Mentha longifolia (L.) Essential Oils from Saudi Arabia
F. Anwar, K. Alkharfy, Najeeb-ur-Rehman, Elsadig H. K. Adam +1 more
201738 citations Open access
Semantic Scholar
Thymoquinone reduces mortality and suppresses early acute inflammatory markers of sepsis in a mouse model.
K. Alkharfy, Ajaz Ahmad, Basit L Jan, M. Raish
2018Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie37 citations
Semantic Scholar
Covid‐19 and thymoquinone: Connecting the dots
Ajaz Ahmad, M. Rehman, P. Ahmad, K. Alkharfy
2020Phytotherapy Research36 citations Open access
Semantic Scholar
Hepatoprotective effect of Commiphora myrrha against d-GalN/LPS-induced hepatic injury in a rat model through attenuation of pro inflammatory cytokines and related genes
Ajaz Ahmad, M. Raish, M. Ganaie, S. Ahmad +4 more
2015Pharmaceutical Biology36 citations Open access
Semantic Scholar
Sinapic acid mitigates methotrexate‐induced hepatic injuries in rats through modulation of Nrf‐2/HO‐1 signaling
Ajaz Ahmad, K. Alkharfy, Yousef A. Bin Jardan, Mudassar Shahid +5 more
2021Environmental Toxicology29 citations
Semantic Scholar
Association between type 2 diabetes mellitus-related SNP variants and obesity traits in a Saudi population
N. Al-Daghri, K. Alkharfy, O. Al-attas, Soundararajan Krishnaswamy +5 more
2014Molecular Biology Reports29 citations
Semantic Scholar
Thymoquinone modulates nitric oxide production and improves organ dysfunction of sepsis.
K. Alkharfy, Ajaz Ahmad, M. Raish, P. Vanhoutte
2015Life Science27 citations
Semantic Scholar
Tocilizumab and Systemic Corticosteroids in the Management of Patients with COVID-19: A Systematic Review and Meta-Analysis
H. Alkofide, Abdullah Almohaizeie, Sara A AlMuhaini, Bashayer Alotaibi +1 more
2021International Journal of Infectious Diseases26 citations Open access
Semantic Scholar
Glucocorticoid Receptor-Targeted Liposomal Codelivery of Lipophilic Drug and Anti-Hsp90 Gene: Strategy to Induce Drug-Sensitivity, EMT-Reversal, and Reduced Malignancy in Aggressive Tumors
S. Mondal, Sudhakar Jinka, Krishnendu Pal, S. Nelli +6 more
2016Molecular Pharmaceutics25 citations Open access
Semantic Scholar
Eudragit-Coated Sporopollenin Exine Microcapsules (SEMC) of Phoenix dactylifera L. of 5-Fluorouracil for Colon-Specific Drug Delivery
Mohammad Raish, M. Kalam, Ajaz Ahmad, Mudassar Shahid +9 more
2021Pharmaceutics23 citations Open access
Semantic Scholar
Effects of Thymoquinone on the Pharmacokinetics and Pharmacodynamics of Glibenclamide in a Rat Model
Ajaz Ahmad, R. M. A. Khan, K. Alkharfy, M. Raish +2 more
2015Natural Product Communications22 citations Open access
Semantic Scholar
Cardamom (Elettaria cardamomum Maton) Oils
F. Anwar, A. Abbas, K. Alkharfy, Anwar H. Gilani
201621 citations
Semantic Scholar
Effects of Nigella sativa, Lepidium sativum and Trigonella foenum-graecum on sildenafil disposition in beagle dogs
A. Al-mohizea, A. Ahad, G. M. El-Maghraby, F. I. Al-Jenoobi +2 more
2015European journal of drug metabolism and pharmacokinetics19 citations
Semantic Scholar
Gender effect on the pharmacokinetics of thymoquinone: Preclinical investigation and in silico modeling in male and female rats
Ajaz Ahmad, S. Alqahtani, Basit L Jan, Mohammad Raish +2 more
2020Saudi Pharmaceutical Journal18 citations Open access
Semantic Scholar
N-acetyltransferase 1 and 2 polymorphisms and risk of diabetes mellitus type 2 in a Saudi population
W. M. Al-Shaqha, K. Alkharfy, N. Al-Daghri, Abdul Khader Mohammed
2015Annals of Saudi Medicine18 citations Open access
Semantic Scholar
Effects of fenugreek, garden cress, and black seed on theophylline pharmacokinetics in beagle dogs
F. I. Al-Jenoobi, A. Ahad, G. Mahrous, A. Al-mohizea +2 more
2015Pharmaceutical Biology18 citations Open access
Semantic Scholar
Increased IL-4 mRNA expression and poly-aromatic hydrocarbon concentrations from children with asthma
N. Al-Daghri, Sherif H. Abd-Alrahman, Hossam M. Draz, K. Alkharfy +3 more
2014BMC Pediatrics17 citations Open access
Semantic Scholar
Effect of sinapic acid on aripiprazole pharmacokinetics in rats: Possible food drug interaction
Mohammad Raish, Ajaz Ahmad, M. A. Ansari, K. Alkharfy +5 more
2018Journal of Food and Drug Analysis16 citations Open access
Semantic Scholar
Antioxidant and Antimicrobial Attributes of Different Solvent Extracts from Leaves of Four Species of Mulberry
F. Anwar, Shamsa Kanwal, G. Shabir, K. Alkharfy +1 more
201516 citations Open access
Semantic Scholar
Pharmacokinetic interaction studies of fenugreek with CYP3A substrates cyclosporine and carbamazepine
F. I. Al-Jenoobi, M. A. Alam, K. Alkharfy, S. Al-suwayeh +5 more
2014European journal of drug metabolism and pharmacokinetics15 citations
Semantic Scholar
Inhibitory effects of Lepidium sativum polysaccharide extracts on TNF-α production in Escherichia coli-stimulated mouse
Ajaz Ahmad, Basit L Jan, M. Raish, K. Alkharfy +4 more
20183 Biotech14 citations Open access
Semantic Scholar
Endothelium-Dependent Contractions of Isolated Arteries to Thymoquinone Require Biased Activity of Soluble Guanylyl Cyclase with Subsequent Cyclic IMP Production
C. M. Detremmerie, Zhengju Chen, Zhuo-Ming Li, K. Alkharfy +4 more
2016Journal of Pharmacology and Experimental Therapeutics14 citations Open access
Semantic Scholar
Mugwort (Artemisia vulgaris) Oils
F. Anwar, N. Ahmad, K. Alkharfy, A. Gilani
201614 citations
Semantic Scholar
Effects of sinapic acid on hepatic cytochrome P450 3A2, 2C11, and intestinal P-glycoprotein on the pharmacokinetics of oral carbamazepine in rats: Potential food/herb-drug interaction.
Mohammad Raish, Ajaz Ahmad, M. A. Ansari, K. Alkharfy +5 more
2019Epilepsy Research13 citations
Semantic Scholar
Antioxidant Potential and In Situ Analysis of Major and Trace Element Determination of Ood-saleeb, a Known Unani Herbal Medicine by ICP-MS
M. Raish, Ajaz Ahmad, K. Alkharfy, F. I. Al-Jenoobi +5 more
2016Biological Trace Element Research12 citations
Semantic Scholar
Development and Validation of RP-HPLC Method for Simultaneous Estimation of Glibenclamide and Thymoquinone in Rat Plasma and Its Application to Pharmacokinetics
Ajaz Ahmad, R. M. A. Khan, K. Alkharfy
201512 citations Open access
Semantic Scholar
Thymoquinone modulates the expression of sepsis-related microRNAs in a CLP model
K. Alkharfy, Ajaz Ahmad, Basit L. Jan, M. Raish +1 more
2022Experimental and Therapeutic Medicine11 citations Open access
Semantic Scholar

Frequent co-authors

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Ajaz Ahmad×31
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Ajaz Ahmad — researcher profile on SciRah
M. Raish×20
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M. Raish — researcher profile on SciRah
F. I. Al-Jenoobi×17
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F. I. Al-Jenoobi — researcher profile on SciRah
M. A. Ansari×14
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M. A. Ansari — researcher profile on SciRah

×13

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A. Ahad — researcher profile on SciRah

A. Al-mohizea×12

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A. Al-mohizea — researcher profile on SciRah

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Basit L Jan — researcher profile on SciRah

Yousef A. Bin Jardan×6

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Yousef A. Bin Jardan — researcher profile on SciRah

Altaf M. Khan×6

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Altaf M. Khan — researcher profile on SciRah

Mohammad Raish×6

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Mohammad Raish — researcher profile on SciRah

Mudassar Shahid×5

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Mudassar Shahid — researcher profile on SciRah

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N. Ali — researcher profile on SciRah