Researcher profile · Semantic Scholar

H. Yajima

h-index: 20
Works: 38
Citations: 1,614

Most-cited papers

Ataxia Telangiectasia Mutated (ATM) Is Essential for DNA-PKcs Phosphorylations at the Thr-2609 Cluster upon DNA Double Strand Break*
B. Chen, Naoya Uematsu, Junya Kobayashi, Y. Lerenthal +5 more
2007Journal of Biological Chemistry306 citations Open access
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ATR-Dependent Phosphorylation of DNA-Dependent Protein Kinase Catalytic Subunit in Response to UV-Induced Replication Stress
H. Yajima, Kyung-jong Lee, B. Chen
2006Molecular and Cellular Biology131 citations Open access
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DNA Double Strand Break Formation upon UV-Induced Replication Stress Activates ATM and DNA-PKcs Kinases
H. Yajima, Kyung-jong Lee, Shi-Chuan Zhang, Junya Kobayashi +1 more
2008Journal of Molecular Biology126 citations Open access
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Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair
Shi-Chuan Zhang, H. Yajima, HoangDinh Huynh, Jun-Ke Zheng +14 more
2011Journal of Cell Biology124 citations Open access
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A eukaryotic gene encoding an endonuclease that specifically repairs DNA damaged by ultraviolet light.
H. Yajima, M. Takao, Shinji Yasuhira, Ji-He Zhao +3 more
1995EMBO Journal121 citations
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The complexity of DNA double strand breaks is a critical factor enhancing end-resection.
H. Yajima, H. Fujisawa, N. Nakajima, Hirokazu Hirakawa +3 more
2013DNA Repair89 citations Open access
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Binding of the N‐terminal 63 kDa portion of connectin/titin to α‐actinin as revealed by the yeast two‐hybrid system
H. Ohtsuka, H. Yajima, K. Maruyama, S. Kimura
1997FEBS Letters88 citations
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Involvement of DNA-dependent Protein Kinase in Normal Cell Cycle Progression through Mitosis*
Kyung-jong Lee, Yu-Fen Lin, Han-Yi E. Chou, H. Yajima +3 more
2011Journal of Biological Chemistry86 citations Open access
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Isolation and genetic characterization of pGKL killer-insensitive mutants (iki) from Saccharomyces cerevisiae.
M. Kishida, Masao Tokunaga, Y. Katayose, H. Yajima +2 more
1996Bioscience, biotechnology and biochemistry72 citations
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The N-Terminal Z Repeat 5 of Connectin/Titin Binds to the C-Terminal Region of α-Actinin
H. Ohtsuka, H. Yajima, K. Maruyama, S. Kimura
199771 citations
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Structure and physiological functions of ubiquitous and tissue-specific calpain species. Muscle-specific calpain, p94, interacts with connectin/titin.
H. Sorimachi, Sumiko Kimura, Kayoko Kinbara, J. Kazama +8 more
1996Advances in Biophysics54 citations
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VE-821, an ATR inhibitor, causes radiosensitization in human tumor cells irradiated with high LET radiation
H. Fujisawa, N. Nakajima, Shigeaki Sunada, Younghyun Lee +5 more
2015Radiation Oncology47 citations Open access
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Mitochondrial DNA repair by photolyase.
Akira Yasui, H. Yajima, Takayasu Kobayashi, A. P. M. Eker +1 more
1992Mutation research39 citations
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A 11.5-kb 5'-terminal cDNA sequence of chicken breast muscle connectin/titin reveals its Z line binding region.
H. Yajima, H. Ohtsuka, Y. Kawamura, H. Kume +4 more
1996Biochemical and Biophysical Research Communications - BBRC35 citations
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High linear-energy-transfer radiation can overcome radioresistance of glioma stem-like cells to low linear-energy-transfer radiation
Y. Hirota, S. Masunaga, Natsuko Kondo, S. Kawabata +6 more
2013Journal of Radiation Research31 citations Open access
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The N-terminal Z repeat 5 of connectin/titin binds to the C-terminal region of alpha-actinin.
H. Ohtsuka, H. Yajima, K. Maruyama, S. Kimura
1997Biochemical and Biophysical Research Communications - BBRC30 citations
Semantic Scholar
Replication stress induced site-specific phosphorylation targets WRN to the ubiquitin-proteasome pathway
Fengtao Su, Souparno Bhattacharya, Salim Abdisalaam, S. Mukherjee +8 more
2015OncoTarget29 citations Open access
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Characterization of IKI1 and IKI3 genes conferring pGKL killer sensitivity on Saccharomyces cerevisiae.
H. Yajima, Masao Tokunaga, Akiko Nakayama-Murayama, Fumio Hishinuma
1997Bioscience, biotechnology and biochemistry28 citations
Semantic Scholar
The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function.
Lian Xue, Y. Furusawa, R. Okayasu, M. Miura +6 more
2015DNA Repair25 citations Open access
Semantic Scholar
Carbon ion beam is more effective to induce cell death in sphere-type A172 human glioblastoma cells compared with X-rays
Momoko Takahashi, Hirokazu Hirakawa, H. Yajima, Nakako Izumi-Nakajima +2 more
2014International Journal of Radiation Biology21 citations Open access
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Identification of a Bcl-XL binding region within the ATPase domain of Apaf-1.
H. Yajima, F. Suzuki
2003Biochemical and Biophysical Research Communications - BBRC13 citations
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Suppression of Postmitochondrial Signaling and Delayed Response to UV‐induced Nuclear Apoptosis in HeLa Cells
K. Sasai, H. Yajima, F. Suzuki
2002Japanese journal of cancer research : Gann11 citations Open access
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Molecular Cloning of a Partial cDNA Clone Encoding the C Terminal Region of Chicken Breast Muscle Connectin
H. Yajima, H. Ohtsuka, H. Kume, T. Endo +3 more
1996Zoological Science10 citations Open access
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Organization of connectin/titin filaments in sarcomeres of differentiating chicken skeletal muscle cells
Y. Soeno, H. Yajima, Y. Kawamura, S. Kimura +2 more
2004Molecular and Cellular Biochemistry9 citations
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A 7.5-kb 3′-Terminal cDNA Sequence of Chicken Skeletal Muscle Nebulin Reveals Its Actin Binding Regions
Takeyuki Suzuki, H. Yajima, K. Maruyama, S. Kimura
2000Zoological Science5 citations Open access
Semantic Scholar
RNF8 promotes high linear energy transfer carbon-ion-induced DNA double-stranded break repair in serum-starved human cells.
N. Nakajima, Motohiro Yamauchi, Sangeeta Kakoti, Cuihua Liu +8 more
2020DNA Repair4 citations Open access
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DNA Repair Processes and Checkpoint Pathways in Human Cells Exposed to Heavy Ion Beams.
H. Yajima, Xue Lian
2015International Journal of Particle Therapy4 citations Open access
Semantic Scholar
Novel characteristics of CtIP at damage-induced foci following the initiation of DNA end resection.
H. Fujisawa, A. Fujimori, R. Okayasu, M. Uesaka +1 more
2015Mutation research3 citations Open access
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Cellular radiosensitivity and cell-type-specific activation of apoptosis signaling pathways
F. Suzuki, Yukimi Akimoto, K. Sasai, H. Yajima
20032 citations
Semantic Scholar
VE-821, an ATR inhibitor, causes radiosensitization in human tumor cells irradiated with high LET radiation
H. Fujisawa, N. Nakajima, Shigeaki Sunada, Younghyun Lee +5 more
2015Radiation Oncology1 citations Open access
Semantic Scholar
Digital Digital Congenital bone marrow failure in DNA-PKcs mutant mice Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair associated with deficiencies in DNA repair
Shi-Chuan Zhang, H. Yajima, HoangDinh Huynh, Jun-Ke Zheng +14 more
20220 citations
Semantic Scholar
Cellular response to DNA end resection
H. Yajima, Cuihua Liu, Xue Lian, N. Nakajima +1 more
20160 citations
Semantic Scholar
DNA double strand break repair pathways and PI3-kinase related protein kinases
H. Yajima
20110 citations
Semantic Scholar
Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair
Shi-Chuan Zhang, H. Yajima, HoangDinh Huynh, Jun-Ke Zheng +14 more
20110 citations
Semantic Scholar
Activation of mitochondrial apoptosis pathways in Jurkat cells irradiated with γ and UV radiation
F. Suzuki, Yukimi Akimoto, H. Yajima
20030 citations
Semantic Scholar
Defect in Caspase Activation and the Delayed Response to UV-Induced Apoptosis in HeLa Cells
F. Suzuki, K. Sasai, H. Yajima
20010 citations
Semantic Scholar
Mitochondrial Release of Cytochrome c and AIF during the Apoptotic Process of Cultured Mammalian Cells
F. Suzuki, K. Sasai, H. Yajima
20000 citations
Semantic Scholar
Genome Abnormality Appeared in X-Irradiated Scid Mouse Embryo Fibroblasts
F. Suzuki, K. Takada, H. Yajima, M. Tatsuka +2 more
19980 citations
Semantic Scholar

A. Fujimori

×6

B. Chen×5

David J. Chen×5

N. Nakajima×5

Hirokazu Hirakawa×5

H. Ohtsuka×5

Shi-Chuan Zhang×4

Yu-Fen Lin×4