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H. Chandramoorthy · SciRah

Researcher profile · Semantic Scholar

H. Chandramoorthy

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H. Chandramoorthy — researcher profile on SciRah

h-index: 20
Works: 90
Citations: 2,628

Most-cited papers

MICU1 is an Essential Gatekeeper for MCU-Mediated Mitochondrial Ca2+ Uptake That Regulates Cell Survival
Karthik Mallilankaraman, Patrick J. Doonan, C. Cárdenas, H. Chandramoorthy +10 more
2012Cell676 citations Open access
Semantic Scholar
MCUR1 is an Essential Component of Mitochondrial Ca2+ Uptake that Regulates Cellular Metabolism
Karthik Mallilankaraman, C. Cárdenas, Patrick J. Doonan, H. Chandramoorthy +13 more
2012Nature Cell Biology434 citations Open access
Semantic Scholar
STIMulating a new treatment for sepsis.
R. Gandhirajan, Shu Meng, H. Chandramoorthy, Karthik Mallilankaraman +11 more
2013Lab animal169 citations Open access
Semantic Scholar
SLC25A23 augments mitochondrial Ca2+ uptake, interacts with MCU, and induces oxidative stress–mediated cell death
N. Hoffman, H. Chandramoorthy, S. Shanmughapriya, Xue-Qiang Zhang +9 more
2014Molecular Biology of the Cell147 citations Open access
Semantic Scholar
MICU1 Motifs Define Mitochondrial Calcium Uniporter Binding and Activity
N. Hoffman, H. Chandramoorthy, Santhanam Shamugapriya, Xue-Qiang Zhang +12 more
2013Cell Reports143 citations Open access
Semantic Scholar
LETM1‐dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation
Patrick J. Doonan, H. Chandramoorthy, N. Hoffman, Xue-Qiang Zhang +9 more
2014The FASEB Journal113 citations Open access
Semantic Scholar
Requirement of FADD, NEMO, and BAX/BAK for Aberrant Mitochondrial Function in Tumor Necrosis Factor Alpha-Induced Necrosis
Krishna M. Irrinki, Karthik Mallilankaraman, Roshan J. Thapa, H. Chandramoorthy +8 more
2011Molecular and Cellular Biology105 citations Open access
Semantic Scholar
B cells help alloreactive T cells differentiate into memory T cells
Yue-Harn Ng, M. Oberbarnscheidt, H. Chandramoorthy, Rosemary A. Hoffman +1 more
2010American Journal of Transplantation79 citations Open access
Semantic Scholar
Antimicrobial Efficiency of Essential Oils from Traditional Medicinal Plants of Asir Region, Saudi Arabia, over Drug Resistant Isolates
I. M. Helal, A. El-Bessoumy, Erwa Al-Bataineh, Martin R. P. Joseph +3 more
2018BioMed Research International71 citations Open access
Semantic Scholar
Sero-prevalence and risk factors of brucellosis among suspected febrile patients attending a referral hospital in southern Saudi Arabia (2014–2018)
A. Alkahtani, M. Assiry, H. Chandramoorthy, A. Al-Hakami +1 more
2020BMC Infectious Diseases55 citations Open access
Semantic Scholar
Corrigenda: MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism
Karthik Mallilankaraman, C. Cárdenas, Patrick J. Doonan, H. Chandramoorthy +13 more
2013Nature Cell Biology39 citations Open access
Semantic Scholar
Thymoquinone attenuates oxidative stress of kidney mitochondria and exerts nephroprotective effects in oxonic acid-induced hyperuricemia rats.
A. Dera, Prasanna Rajagopalan, Mohammad A. Alfhili, Irfan Ahmed +1 more
2019Biofactors31 citations
Semantic Scholar
Mesenchymal Stem Cells (MSCs) Coculture Protects [Ca2+]i Orchestrated Oxidant Mediated Damage in Differentiated Neurons In Vitro
A. Alhazzani, Prasanna Rajagopalan, Zaher Albarqi, Anantharam Devaraj +3 more
2018Cells30 citations Open access
Semantic Scholar
COVID-19 influenced gut dysbiosis, post-acute sequelae, immune regulation, and therapeutic regimens
Sterlin T. Raj, Alexander Bruce, M. Anbalagan, Hemalatha Srinivasan +5 more
2024Frontiers in Cellular and Infection Microbiology25 citations Open access
Semantic Scholar
Biological evaluation of 2-arylidene-4, 7-dimethyl indan-1-one (FXY-1): a novel Akt inhibitor with potent activity in lung cancer
Prasanna Rajagopalan, Khalid A. Alahmari, Ashraf A. Elbessoumy, Meenakshisundaram Balasubramaniam +3 more
2016Cancer Chemotherapy and Pharmacology24 citations
Semantic Scholar
Cytokine physiognomies of MSCs from varied sources confirm the regenerative commitment post‐coculture with activated neutrophils
A. Al-Hakami, Saad Qaddah Alqhatani, Sharaz Shaik, Saaed Mohammed Jalfan +5 more
2020Journal of Cellular Physiology23 citations
Semantic Scholar
FCX‐146, a potent allosteric inhibitor of Akt kinase in cancer cells: Lead optimization of the second‐generation arylidene indanone scaffold
Meenakshisundaram Balasubramaniam, Naga Rajiv Lakkaniga, A. Dera, M. Al Fayi +5 more
2020Biotechnology and applied biochemistry22 citations
Semantic Scholar
Clinical Theragnostic Potential of Diverse miRNA Expressions in Prostate Cancer: A Systematic Review and Meta-Analysis
R. Jayaraj, Greg Raymond, S. Krishnan, Katherine S. Tzou +6 more
2020Cancers22 citations Open access
Semantic Scholar
Healthcare workers’ perspectives on healthcare-associated infections and infection control practices: a video-reflexive ethnography study in the Asir region of Saudi Arabia
E. Paul, Ibrahim A. Alzaydani Asiri, A. Al-Hakami, H. Chandramoorthy +4 more
2020Antimicrobial Resistance and Infection Control20 citations Open access
Semantic Scholar
Indirubin-3-monoxime and thymoquinone exhibit synergistic efficacy as therapeutic combination in in-vitro and in-vivo models of Lung cancer
A. Dera, Prasanna Rajagopalan, M. Al Fayi, Irfan Ahmed +1 more
2020Archives of pharmacal research20 citations
Semantic Scholar
Prevalence of toxoplasmosis, rubella, cytomegalovirus, and herpes (TORCH) infections among women attending the antenatal care clinic, maternity hospital in Abha, Southwestern Saudi Arabia
A. Al-Hakami, E. Paul, Faten Al-Abed, Ahmad A Alzoani +6 more
2020Saudi Medical Journal20 citations Open access
Semantic Scholar
Clinical Relevance and Antimicrobial Profiling of Methicillin-Resistant Staphylococcus aureus (MRSA) on Routine Antibiotics and Ethanol Extract of Mango Kernel (Mangifera indica L.)
A. A. Al Bshabshe, Martin R. P. Joseph, Amgad A. Awad El-Gied, Abdalla N. Fadul +2 more
2020BioMed Research International19 citations Open access
Semantic Scholar
Thymoquinone attenuates IgE-mediated allergic response via pi3k-Akt-NFκB pathway and upregulation of the Nrf2-HO1 axis.
A. Dera, Prasanna Rajagopalan, Irfan Ahmed, Mohammad A. Alfhili +2 more
2020Journal of food biochemistry19 citations Open access
Semantic Scholar
MSCs ameliorates DPN induced cellular pathology via [Ca2+]i homeostasis and scavenging the pro‐inflammatory cytokines
H. Chandramoorthy, I. Bin-Jaliah, Hussian Karari, Prasanna Rajagopalan +7 more
2018Journal of Cellular Physiology19 citations
Semantic Scholar
Differentiated mesenchymal stem cells ameliorate cardiovascular complications in diabetic rats
M. Haidara, Abdullah S. Assiri, Mary A. Youssef, Manal A. M. Mahmoud +3 more
2015Cell and Tissue Research19 citations
Semantic Scholar
In vitro evaluation of anticancer effect of Cassia auriculata leaf extract and curcumin through induction of apoptosis in human breast and larynx cancer cell lines
R. Prasanna, H. Chandramoorthy, Pichai Ramaiyapillai, D. Sakthisekaran
201119 citations
Semantic Scholar
Synthesis, pharmacological evaluation, and molecular modeling studies of novel isatin hybrids as potential anticancer agents
Rajapandi Raju, K. Chidambaram, B. Chandrasekaran, Mohammad F. Bayan +3 more
2023Journal of Saudi Chemical Society16 citations Open access
Semantic Scholar
Inhibition realization of multidrug resistant bacterial and fungal isolates using Coccinia indica extracts
M. Alshahrani, E. Ibrahim, M. Asiri, M. Kilany +4 more
2022Saudi Journal of Biological Sciences16 citations Open access
Semantic Scholar
Anti-cancer activity of ethanolic leaf extract of Salvia officinalis against oral squamous carcinoma cells in vitro via caspase mediated mitochondrial apoptosis
Irfan Ahmad, Prasanna Rajagopalan, Shadma Wahab, A. Dera +5 more
202015 citations
Semantic Scholar
Antimicrobial activity of Triphala against bacterial isolates from HIV infected patients
Safiullah Amanullah, H. Chandramoorthy, Vijay Kumar, Saira Khatheeja
201115 citations
Semantic Scholar
Lycopene Scavenges Cellular ROS, Modulates Autophagy and Improves Survival through 7SK snRNA Interaction in Smooth Muscle Cells
A. Shati, R. Eid, M. S. A. Zaki, Y. Alqahtani +2 more
2022Cells14 citations Open access
Semantic Scholar
Rational combinations of indirubin and arylidene derivatives exhibit synergism in human non-small cell lung carcinoma cells.
Prasanna Rajagopalan, A. Dera, Mohamad Ragab Abdalsamad, H. Chandramoorthy
2019Journal of food biochemistry14 citations Open access
Semantic Scholar
Antimicrobial Activity of Cold Atmospheric Plasma on Bacterial Strains Derived from Patients with Diabetic Foot Ulcers
Roopak Murali, Pooja Singh, Divya Ragunathan, Ramya Damarla +7 more
2024Journal of Microbiology and Biotechnology13 citations
Semantic Scholar
A Clinical Update on the Prognostic Effect of microRNA Biomarkers for Survival Outcome in Nasopharyngeal Carcinoma: A Systematic Review and Meta-Analysis
Peter Shaw, R. Senthilnathan, S. Krishnan, D. Suresh +8 more
2021Cancers13 citations Open access
Semantic Scholar
Cassia auriculata leaf extract ameliorates diabetic nephropathy by attenuating autophagic necroptosis via RIP-1/RIP-3-p-p38MAPK signaling.
Mesfer Al Shahrani, H. Chandramoorthy, M. Alshahrani, Mohammad Abohassan +3 more
2021Journal of food biochemistry13 citations Open access
Semantic Scholar
Proteomic profiling of various human dental stem cells - a systematic review
J. Hosmani, K. Assiri, H. Almubarak, M. Mannakandath +6 more
2020World Journal of Stem Cells13 citations Open access
Semantic Scholar
GC-MS analysis of ethanol extract from areal parts of Nepeta deflersiana and its anticancer and antimicrobial efficacies
Irfan Ahmad, Safia Irfan, A. Dera, G. Zaman +3 more
2020Biologia13 citations
Semantic Scholar
Synergistic antibacterial and mosquitocidal effect of Passiflora foetida synthesized silver nanoparticles.
D. Palanisamy, B. Gounder, K. Selvaraj, S. Kandhasamy +9 more
2023Brazilian journal of biology = Revista brasleira de biologia11 citations Open access
Semantic Scholar
Appraising the therapeutical potentials of Alchornea laxiflora (Benth.) Pax & K. Hoffm., an underexplored medicinal herb: A systematic review
N. Jain, M. Tailang, Santosh Kumar, B. Chandrasekaran +7 more
2022Frontiers in Pharmacology11 citations Open access
Semantic Scholar
High altitude as a possible factor for dysbiosis of salivary microbiome in orthodontic patients.
I. Alshahrani, J. Hosmani, Abdulaziz Alshahrani, R. Togoo +4 more
2020Archives of Oral Biology9 citations
Semantic Scholar
Exosomes as key mediators in immune and cancer cell interactions: insights in melanoma progression and therapy
Chou-Yi Hsu, H. Chandramoorthy, J. Mohammed, Shaker Al-Hasnaawei +6 more
2025Archives of Dermatological Research7 citations
Semantic Scholar
Bone Marrow Mesenchymal Stromal Cells (BMMSCs) Augment Osteointegration of Dental Implants in Type 1 Diabetic Rabbits: An X-Ray Micro-Computed Tomographic Evaluation
Nabeeh Abdullah Alqahtani, H. Chandramoorthy, Sharaz Shaik, J. Syed +2 more
2020Medicina7 citations Open access
Semantic Scholar
Human metapneumovirus in Pediatric Patients with Acute Respiratory Tract Infections in the Aseer Region of Saudi Arabia
A. Alsuheel, A. Ali, A. Al-Hakami, A. Shati +2 more
2019Saudi Journal of Medicine and Medical Sciences7 citations Open access
Semantic Scholar
Mapping Research on miRNAs in Cancer: A Global Data Analysis and Bibliometric Profiling Analysis
Peter Shaw, Kartik Lokhotiya, C. Kumarasamy, Krishnan Sunil +10 more
2022Pathophysiology6 citations Open access
Semantic Scholar
Clinical Theragnostic Relationship between Chemotherapeutic Resistance, and Sensitivity and miRNA Expressions in Head and Neck Cancers: A Systematic Review and Meta-Analysis Protocol
Peter Shaw, Greg Raymond, R. Senthilnathan, C. Kumarasamy +10 more
2021Genes5 citations Open access
Semantic Scholar
Diagnostic implications of miRNAs in Liquid Biopsy for Oral Squamous Cell Carcinoma (OSCC): Clinical validity and interpretation.
R. Jayaraj, Chellan Kumaraswamy, Greg Raymond, Ravishankar Ram Mani +3 more
2020Oral Oncology5 citations Open access
Semantic Scholar
Lycopene augments and enhances anti-oxidant/antibacterial efficiency of ethanolic leaf extract of Helianthus annuus over multidrug-resistant bacterial isolates
M. Alshahrani, Essam H Ibrahim, M. Asiri, M. Kilany +3 more
2022Journal of King Saud University: Science4 citations Open access
Semantic Scholar
Deciphering cGAS-STING signaling: implications for tumor immunity and hepatocellular carcinoma
H. Chandramoorthy, R. O. Saleh, F. Altalbawy, J. Mohammed +6 more
2025Naunyn-Schmiedeberg's Archives of Pharmacology3 citations
Semantic Scholar
Clocking the damage: circadian rhythm, redox homeostasis and genome integrity in cancer.
Jeyasree M Ganesh, Pooja Singh, Roopak Murali, H. Chandramoorthy +2 more
2025Molecular and Cellular Biochemistry3 citations
Semantic Scholar
FPX-113 attenuates inflammatory responses by deteriorating cytokines, neutrophil activity and mast cell degranulation via Akt/ NF- κB pathway
Prasanna Rajagopalan, A. Dera, Mohamad Ragab Abdalsamad, M. Al Fayi +2 more
2019Biologia3 citations
Semantic Scholar

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