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Reza M. H. Khorooshi · SciRah

Researcher profile · Semantic Scholar

Reza M. H. Khorooshi

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Reza M. H. Khorooshi — researcher profile on SciRah

h-index: 19
Works: 63
Citations: 1,635

Most-cited papers

A novel microglial subset plays a key role in myelinogenesis in developing brain
Agnieszka Włodarczyk, I. Holtman, M. Krueger, N. Yogev +11 more
2017EMBO Journal447 citations Open access
Semantic Scholar
Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties
C. K. Prajeeth, Julius Kronisch, Reza M. H. Khorooshi, B. Knier +7 more
2017Journal of Neuroinflammation119 citations Open access
Semantic Scholar
Interferons in the central nervous system: A few instruments play many tunes
T. Owens, Reza M. H. Khorooshi, Agnieszka Włodarczyk, N. Asgari
2014Glia116 citations
Semantic Scholar
Injury-Induced Type I IFN Signaling Regulates Inflammatory Responses in the Central Nervous System
Reza M. H. Khorooshi, T. Owens
2010Journal of Immunology89 citations Open access
Semantic Scholar
NF-κB-Driven STAT2 and CCL2 Expression in Astrocytes in Response to Brain Injury1
Reza M. H. Khorooshi, A. Babcock, T. Owens
2008Journal of Immunology77 citations Open access
Semantic Scholar
Induction of endogenous Type I interferon within the central nervous system plays a protective role in experimental autoimmune encephalomyelitis
Reza M. H. Khorooshi, M. T. Mørch, T. H. Holm, Carsten Tue Berg +6 more
2015Acta Neuropathologica75 citations Open access
Semantic Scholar
Pathologic and Protective Roles for Microglial Subsets and Bone Marrow- and Blood-Derived Myeloid Cells in Central Nervous System Inflammation
Agnieszka Włodarczyk, O. Cédile, Kirstine Nolling Jensen, A. Jasson +3 more
2015Frontiers in Immunology73 citations Open access
Semantic Scholar
Angiotensin II Type 1 receptor (AT1) signaling in astrocytes regulates synaptic degeneration-induced leukocyte entry to the central nervous system.
L. Füchtbauer, M. Groth-Rasmussen, T. H. Holm, Morten Løbner +3 more
2011Brain, behavior, and immunity51 citations
Semantic Scholar
Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice
M. Salem, J. Mony, Morten Løbner, Reza M. H. Khorooshi +1 more
2011Journal of Neuroinflammation49 citations Open access
Semantic Scholar
Endogenous IFN-β signaling exerts anti-inflammatory actions in experimentally induced focal cerebral ischemia
A. Inácio, Ya-Wei Liu, B. Clausen, Martina Svensson +7 more
2015Journal of Neuroinflammation46 citations Open access
Semantic Scholar
Complement-dependent pathogenicity of brain-specific antibodies in cerebrospinal fluid.
N. Asgari, Reza M. H. Khorooshi, S. Lillevang, T. Owens
2013Journal of Neuroimmunology46 citations
Semantic Scholar
Syddansk Universitet Cerebrospinal fluid aquaporin-4-immunoglobulin G disrupts blood brain barrier
N. Asgari, Carsten Tue Berg, M. T. Mørch, Reza M. H. Khorooshi +1 more
201544 citations
Semantic Scholar
Blood–brain barrier disruption in CCL2 transgenic mice during pertussis toxin-induced brain inflammation
Angela E. Schellenberg, R. Buist, M. D. Del Bigio, Henrik Toft-hansen +3 more
2012Fluids and Barriers of the CNS37 citations Open access
Semantic Scholar
Neuronal distribution of melanin-concentrating hormone, cocaine- and amphetamine-regulated transcript and orexin B in the brain of the Djungarian hamster (Phodopus sungorus).
Reza M. H. Khorooshi, M. Klingenspor
2005Journal of Chemical Neuroanatomy35 citations
Semantic Scholar
Chemokine receptor expression by inflammatory T cells in EAE
J. Mony, Reza M. H. Khorooshi, T. Owens
2014Frontiers in Cellular Neuroscience34 citations Open access
Semantic Scholar
Neuromyelitis optica-like pathology is dependent on type I interferon response.
Reza M. H. Khorooshi, Agnieszka Włodarczyk, N. Asgari, T. Owens
2013Experimental Neurology31 citations
Semantic Scholar
Protective roles for myeloid cells in neuroinflammation
T. Owens, A. Benmamar-Badel, Agnieszka Włodarczyk, J. Marczyńska +6 more
2020Scandinavian Journal of Immunology26 citations Open access
Semantic Scholar
Lentiviral-mediated administration of IL-25 in the CNS induces alternative activation of microglia
Chiara Maiorino, Reza M. H. Khorooshi, Francesca Ruffini, Morten Løbner +5 more
2012Gene Therapy24 citations Open access
Semantic Scholar
Type I interferon‐activated microglia are critical for neuromyelitis optica pathology
Agnieszka Włodarczyk, Reza M. H. Khorooshi, J. Marczyńska, I. Holtman +8 more
2020Glia23 citations Open access
Semantic Scholar
Influence of type I IFN signaling on anti-MOG antibody-mediated demyelination
Carsten Tue Berg, Reza M. H. Khorooshi, N. Asgari, T. Owens
2017Journal of Neuroinflammation19 citations Open access
Semantic Scholar
Surfactant Protein D Deficiency in Mice Is Associated with Hyperphagia, Altered Fat Deposition, Insulin Resistance, and Increased Basal Endotoxemia
J. Stidsen, Reza M. H. Khorooshi, Martin K. U. Rahbek, K. Kirketerp-Møller +10 more
2012PLoS ONE16 citations Open access
Semantic Scholar
Innate signaling within the central nervous system recruits protective neutrophils
Reza M. H. Khorooshi, J. Marczyńska, R. Dieu, Vian Wais +7 more
2020Acta Neuropathologica Communications15 citations Open access
Semantic Scholar
MOG extracellular domain (p1–125) triggers elevated frequency of CXCR3+ CD4+ Th1 cells in the CNS of mice and induces greater incidence of severe EAE
J. Mony, Reza M. H. Khorooshi, T. Owens
2014Multiple Sclerosis14 citations
Semantic Scholar
Hypersensitivity Responses in the Central Nervous System
Reza M. H. Khorooshi, N. Asgari, M. T. Mørch, Carsten Tue Berg +1 more
2015Frontiers in Immunology13 citations Open access
Semantic Scholar
Central Nervous System-Endogenous TLR7 and TLR9 Induce Different Immune Responses and Effects on Experimental Autoimmune Encephalomyelitis
R. Dieu, Vian Wais, Michael Zaucha Sørensen, J. Marczyńska +7 more
2021Frontiers in Neuroscience12 citations Open access
Semantic Scholar
An Experimental Model of Neuromyelitis Optica Spectrum Disorder–Optic Neuritis: Insights Into Disease Mechanisms
Sofie Forsberg Soerensen, M. Wirenfeldt, Agnieszka Włodarczyk, M. T. Moerch +5 more
2021Frontiers in Neurology12 citations Open access
Semantic Scholar
Expression of Astrocytic Type 2 Angiotensin Receptor in Central Nervous System Inflammation Correlates With Blood–Brain Barrier Breakdown
L. Füchtbauer, Henrik Toft-hansen, Reza M. H. Khorooshi, T. Owens
2010Journal of Molecular Neuroscience12 citations
Semantic Scholar
SARS-CoV-2 and Immunity: Natural Infection Compared with Vaccination
S. Vespa, P. Simeone, Giulia Catitti, Davide Buca +11 more
2022International Journal of Molecular Sciences10 citations Open access
Semantic Scholar
Angiotensin AT2 receptor–induced interleukin-10 attenuates neuromyelitis optica spectrum disorder–like pathology
Reza M. H. Khorooshi, Emil Ulrikkaholm Tofte-Hansen, Camilla Tygesen, Roser Montanana-Rosell +5 more
2019Multiple Sclerosis10 citations Open access
Semantic Scholar
Seasonal regulation of cocaine- and amphetamine-regulated transcript in the arcuate nucleus of Djungarian hamster (Phodopus sungorus).
Reza M. H. Khorooshi, M. Helwig, Achim Werckenthin, N. Steinberg +1 more
2008General and Comparative Endocrinology9 citations
Semantic Scholar
Detection and cellular localization of phospho-STAT2 in the central nervous system by immunohistochemical staining.
Reza M. H. Khorooshi, T. Owens
2013Methods in molecular biology7 citations
Semantic Scholar
PEGylated liposomes via ATRP for brain drug delivery
Lulu Chen, Zhen-Fang Zhang, Maria R. Simonsen, Trevor Owens +2 more
2025Journal of liposome research6 citations Open access
Semantic Scholar
Innate Signaling in the CNS Prevents Demyelination in a Focal EAE Model
M. Dubik, J. Marczyńska, M. T. Mørch, G. Webster +4 more
2021Frontiers in Neuroscience6 citations Open access
Semantic Scholar
Selective localization of IgG from cerebrospinal fluid to brain parenchyma
M. T. Mørch, Sofie Forsberg Sørensen, Reza M. H. Khorooshi, N. Asgari +1 more
2018Journal of Neuroinflammation6 citations Open access
Semantic Scholar
Targeting Signaling Pathway Downstream of RIG-I/MAVS in the CNS Stimulates Production of Endogenous Type I IFN and Suppresses EAE
Anne K. Kronborg Hansen, M. Dubik, J. Marczyńska, Bhavya Ojha +5 more
2022International Journal of Molecular Sciences4 citations Open access
Semantic Scholar
FACS-Proteomics strategy toward extracellular vesicles single-phenotype characterization in biological fluids: exploring the role of leukocyte-derived EVs in multiple sclerosis
M. C. Cufaro, P. Lanuti, Domenico De Bellis, S. Veschi +13 more
2025Journal of Translational Medicine3 citations Open access
Semantic Scholar
Synergistic Targeting of Innate Receptors TLR7 and NOD2 for Therapeutic Intervention in Multiple Sclerosis
M. Dubik, Joanna Marczyńska-Grzelak, Michael Zaucha Sørensen, R. Dieu +10 more
2024International Journal of Molecular Sciences3 citations Open access
Semantic Scholar
Mitochondria-A target for attenuation of astrocyte pathology.
M. T. Mørch, Reza M. H. Khorooshi, J. Marczyńska, M. Dubik +4 more
2021Journal of Neuroimmunology3 citations Open access
Semantic Scholar
Blood–brain barrier disruption in CCL2 transgenic mice during pertussis toxin-induced brain inflammation
Angela E. Schellenberg, R. Buist, M. D. Del Bigio, Henrik Toft-hansen +3 more
2012Fluids and Barriers of the CNS3 citations Open access
Semantic Scholar
STING Signaling Deficiency Exacerbates Demyelination and Immune Infiltration in Focal EAE Lesions
M. T. Mørch, Line S Reinert, A. Benmamar-Badel, M. Dubik +7 more
2025The Neuroscientist2 citations Open access
Semantic Scholar
The protective effect of Angiotensin AT2-receptor stimulation in Neuromyelitis optica spectrum disorder is independent of astrocyte-derived BDNF.
Reza M. H. Khorooshi, J. Marczyńska, M. Dubik, R. Dieu +7 more
2021Multiple Sclerosis and Related Disorders2 citations Open access
Semantic Scholar
Influence of type I IFN signaling on anti-MOG antibody-mediated demyelination
Carsten Tue Berg, Reza M. H. Khorooshi, N. Asgari, T. Owens
2017Journal of Neuroinflammation2 citations Open access
Semantic Scholar
Cerebrospinal Fluid Aquaporin-4-Immunoglobulin G induces blood brain barrier breakdown
N. Asgari, Carsten Tue Berg, M. T. Mørch, Reza M. H. Khorooshi +1 more
20161 citations
Semantic Scholar
Innate Interferons Regulate CNS Inflammation
R. Dieu, Reza M. H. Khorooshi, Anne Mariboe, M. Arpe +1 more
20161 citations
Semantic Scholar
Type I interferon and receptor activator ofnuclear factor Kappa B signaling withinthe central nervous system
Reza M. H. Khorooshi, R. Dieu, M. Arpe, O. Cédile +3 more
20161 citations Open access
Semantic Scholar
Microglia changes in rat dorsal cochlear nucleus correlate to behavioural tinnitus evidence
P. Perin, Alessandro Venturino, Carsten Tue Berg, G. Sanchini +11 more
20151 citations
Semantic Scholar
Scandinavian Society for Immunology 42nd Annual Meeting Reykjavik, Iceland, June 11–14, 2014
Eirik Sundlisæter, Reidunn J. Edelmann, J. Hol, Junbai Wang +22 more
20141 citations Open access
Semantic Scholar
This information is current as Central Nervous System Regulates Inflammatory Responses in the Injury-Induced Type I IFN Signaling
Reza M. H. Khorooshi, T. Owens
20101 citations
Semantic Scholar
Abstract
P. Khaledi, O. Aula, Jessica Engel, Yuan-Hao Yang +412 more
2026Scandinavian Journal of Immunology0 citations
Semantic Scholar
Laser-Induced Cortical Lesions in Mice as a Model for Progressive Multiple Sclerosis Pathology
Bhavya Ojha, Bita Ramazani, Rouhin Belal, Jonathan Krieger +7 more
2025Biomedicines0 citations Open access
Semantic Scholar

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