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W. P. Watson · SciRah

Researcher profile · Semantic Scholar

W. P. Watson

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W. P. Watson — researcher profile on SciRah

h-index: 18
Works: 77
Citations: 1,213

Most-cited papers

Computer prediction of possible toxic action from chemical structure: an update on the DEREK system.
J. Ridings, M. Barratt, R. Cary, C. Earnshaw +8 more
1996Toxicology210 citations
Semantic Scholar
Monitoring human occupational and environmental exposures to polycyclic aromatic compounds.
H. Brandt, W. P. Watson
2003Annals of Occupational Hygiene125 citations
Semantic Scholar
Role of biomarkers in monitoring exposures to chemicals: present position, future prospects
W. P. Watson, A. Mutti
2004Biomarkers84 citations
Semantic Scholar
Possible mechanisms of carcinogenesis after exposure to benzene.
B. Golding, W. P. Watson
1999IARC scientific publications71 citations
Semantic Scholar
The relationships between alkylation of haemoglobin and DNA in Fischer 344 rats exposed to [14C]ethylene oxide.
D. Potter, D. Blair, R. Davies, W. P. Watson +1 more
1989Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement40 citations
Semantic Scholar
In vitro metabolism of chloroprene: species differences, epoxide stereochemistry and a de-chlorination pathway.
L. Cottrell, B. Golding, Tony Munter, W. P. Watson
2001Chemical Research in Toxicology36 citations Open access
Semantic Scholar
The mechanism of decomposition of N-methyl-N-nitrosourea (MNU) in water and a study of its reactions with 2'-deoxyguanosine, 2'-deoxyguanosine 5'-monophosphate and d(GTGCAC)
B. Golding, C. Bleasdale, Joseph McGinnis, Susanna Müller +4 more
199734 citations
Semantic Scholar
Comparison of the metabolism of ethylene glycol and glycolic acid in vitro by precision-cut tissue slices from female rat, rabbit and human liver
Ewan D. Booth, O. Dofferhoff, P. Boogaard, W. P. Watson
2004Xenobiotica; the fate of foreign compounds in biological systems33 citations
Semantic Scholar
Identification of adducts derived from reactions of (1-chloroethenyl)oxirane with nucleosides and calf thymus DNA.
T. Munter, L. Cottrell, S. Hill, L. Kronberg +2 more
2002Chemical Research in Toxicology33 citations Open access
Semantic Scholar
A new role for glutathione: protection of vitamin B12 from depletion by xenobiotics.
W. P. Watson, T. Munter, B. Golding
2004Chemical Research in Toxicology32 citations Open access
Semantic Scholar
Metabolism and molecular toxicology of isoprene.
W. P. Watson, L. Cottrell, Daping Zhang, B. Golding
2001Chemico-Biological Interactions32 citations
Semantic Scholar
An immunoassay for monitoring human exposure to ethylene oxide.
M. J. Wraith, W. P. Watson, C. Eadsforth, N. J. van Sittert +2 more
1988IARC scientific publications32 citations
Semantic Scholar
Detoxication pathways involving glutathione and epoxide hydrolase in the in vitro metabolism of chloroprene.
T. Munter, L. Cottrell, B. Golding, W. P. Watson
2003Chemical Research in Toxicology29 citations Open access
Semantic Scholar
Simple syntheses of isomers of muconaldehyde and 2-methylmuconaldehyde
B. Golding, G. Kennedy, W. P. Watson
198828 citations
Semantic Scholar
Reactions of benzene oxide with thiols including glutathione.
Alistair P. Henderson, Martine L Barnes, C. Bleasdale, Richard Cameron +7 more
2005Chemical Research in Toxicology25 citations Open access
Semantic Scholar
The metabolism and molecular toxicology of chloroprene.
T. Munter, L. Cottrell, Rikas Ghai, B. Golding +1 more
2007Chemico-Biological Interactions23 citations Open access
Semantic Scholar
Studies on the dermal and systemic bioavailability of polycyclic aromatic compounds in high viscosity oil products
D. Potter, Ewan D. Booth, H. Brandt, R. W. Loose +3 more
1999Archives of Toxicology22 citations
Semantic Scholar
DNA adducts in rats and mice following exposure to [4-14C]-1,2-epoxy-3-butene and to [2,3-14C]-1,3-butadiene.
P. Boogaard, K. D. de Kloe, Ewan D. Booth, W. P. Watson
2004Chemico-Biological Interactions19 citations
Semantic Scholar
Evidence for the formation of Michael adducts from reactions of (E,E)-muconaldehyde with glutathione and other thiols.
Alistair P. Henderson, C. Bleasdale, K. Delaney, A. Lindstrom +4 more
2005Bioorganic chemistry (Print)18 citations Open access
Semantic Scholar
Dose responses for the formation of hemoglobin adducts and urinary metabolites in rats and mice exposed by inhalation to low concentrations of 1,3-[2,3-(14)C]-butadiene.
Ewan D. Booth, J. Kilgour, W. P. Watson
2004Chemico-Biological Interactions18 citations
Semantic Scholar
Dose responses for DNA adduct formation in tissues of rats and mice exposed by inhalation to low concentrations of 1,3-[2,3-[(14)C]-butadiene.
Ewan D. Booth, J. Kilgour, Stephen A Robinson, W. P. Watson
2004Chemico-Biological Interactions17 citations
Semantic Scholar
A novel DNA adduct, originating from 1,2-epoxy-3,4-butanediol, is the major DNA adduct after exposure to [2,3-14C]-1,3-butadiene, but not after exposure to [4-14C]-1,2-epoxy-3-butene
P. Boogaard, N. J. van Sittert, W. P. Watson, K. D. de Kloe
200115 citations
Semantic Scholar
Dimer and trimer of malonaldehyde
B. Golding, Naina Patel, W. P. Watson
198915 citations
Semantic Scholar
In Situ detection of DNA adducts formed in cultured cells by Benzo(a)pyrene diolepoxide (BPDE), with monoclonal antibodies specific for the BP‐Deoxyguanosine Adduct
R. Baan, P. T. M. van den Berg, W. P. Watson, R. Smith
198815 citations
Semantic Scholar
Conversion of (+)-(R)-Limonene into (+)-(1S,4R)-p-mentha-2,8-dien-1-ol, an intermediate in the synthesis of tetrahydrocannabinoids
R. W. Rickards, W. P. Watson
198012 citations
Semantic Scholar
Correlation of 32P-postlabelling-detection of DNA adducts in mouse skin in vivo with the polycyclic aromatic compound content and mutagenicity in Salmonella typhimurium of a range of oil products
Ewan D. Booth, H. Brandt, R. W. Loose, W. P. Watson
1998Archives of Toxicology11 citations
Semantic Scholar
A model system based on photodecompositions of alkylcobaloximes for the conversion of 1,2-diols to aldehydes catalysed by diol dehydrase
B. Golding, T. J. Kemp, C. Sell, P. J. Sellars +1 more
197811 citations
Semantic Scholar
Development of a carcinogenic potency index for dermal exposure to viscous oil products
H. Brandt, Ewan D. Booth, P. D. de Groot, W. P. Watson
1999Archives of Toxicology10 citations
Semantic Scholar
Evaluation of modified bacterial mutagenicity assays for the genotoxicity testing of mineral oils.
T. Brooks, R. Priston, A. Wright, W. P. Watson
1995Mutagenesis10 citations
Semantic Scholar
Attempted kinetic resolution of 1,2-diols by camphorquinone: generation of (R)-(chloromethyl)oxirane
M. Ellis, B. Golding, A. B. Maude, W. P. Watson
199110 citations
Semantic Scholar
Molecular dosimetry of DNA adducts in rainbow trout (Oncorhynchus mykiss) exposed to benzo(a)pyrene by different routes
D. Potter, Thomas M. Clarius, A. Wright, W. P. Watson
2009Archives of Toxicology8 citations
Semantic Scholar
Molecular approaches to assess cancer risks
W. P. Watson, N. J. van Sittert
19958 citations
Semantic Scholar
Synthesis of [15N]guanosines and deoxy[15N]guanosines from 5-amino-1-(β-D-ribofuranosyl)imidazole-4-carboxamide (‘AICA-riboside’)
C. Bleasdale, S. Ellwood, B. Golding, P. K. Slaich +2 more
19948 citations
Semantic Scholar
The mechanism of decomposition of N-methyl-N-nitrosourea in aqueous solution according to 13C and 15N NMR studies: quantitative fragmentation to cyanate
C. Bleasdale, B. Golding, Joseph McGinnis, Susanna Müller +1 more
19918 citations
Semantic Scholar
Intrinsic reactivities in the alkylations of protected amino acids by (R)- and (S)-methyloxirane
M. Ellis, B. Golding, W. P. Watson
19858 citations
Semantic Scholar
3,3,3-Trifluoropropan-1-OL and 3,3,3-trifluoropropanal
B. Golding, P. J. Sellars, W. P. Watson
19858 citations
Semantic Scholar
Stereochemical and kinetic comparisons of mono- and diepoxide formation in the in vitro metabolism of isoprene by liver microsomes from rats, mice, and humans.
B. Golding, L. Cottrell, D. Mackay, Daping Zhang +1 more
2003Chemical Research in Toxicology7 citations Open access
Semantic Scholar
Use of organ cultures in human risk assessment: Comparisons of benzo[a]pyrene-DNA adducts in mouse and human skin.
W. P. Watson, R. Smith, K. Huckle, A. Wright
1989Toxicology in Vitro7 citations
Semantic Scholar
Species differences in the stereochemistry of the metabolism of isoprene in vitro.
R. Small, B. Golding, W. P. Watson
1997Xenobiotica; the fate of foreign compounds in biological systems6 citations
Semantic Scholar
Prospective detection and assessment of genotoxic hazards: a critical appreciation of the contribution of L. Ehrenberg.
A. Wright, T. Bradshaw, W. P. Watson
1988IARC scientific publications6 citations
Semantic Scholar
The effect of vitamin B12 on DNA adduction by styrene oxide, a genotoxic xenobiotic.
W. P. Watson, T. Munter, B. Golding
2023Chemico-Biological Interactions5 citations Open access
Semantic Scholar
Synthesis of enantiopure isoprene epoxides from (S)-lactic acid via ‘dispoke’ intermediates
Daping Zhang, C. Bleasdale, B. Golding, W. P. Watson
20005 citations Open access
Semantic Scholar
A postlabelling assay for N7-(2-oxoethyl)guanine, the principal vinyl chloride-DNA adduct.
W. P. Watson, A. E. Crane, R. Davis, R. Smith +1 more
1987Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement5 citations
Semantic Scholar
The structures of adducts from the reaction between guanosine and glycidaldehyde (oxiranecarbaldehyde): a 15N labelling study
B. Golding, P. K. Slaich, W. P. Watson
19865 citations
Semantic Scholar
Conversion of ‘AICA-riboside’ into [15N]guanosines
B. Golding, P. K. Slaich, W. P. Watson
19865 citations
Semantic Scholar
The structures of nitronate salts in solution as determined by 13C and 1H n.m.r. spectroscopy
W. R. Bowman, B. Golding, W. P. Watson
19805 citations
Semantic Scholar
Degradation of cobaloximes to derivatives of imidazo[1,2-a]pyridine
N. Alcock, B. Golding, D. Hall, U. Horn +1 more
19755 citations
Semantic Scholar
Influence of the methyl group in isoprene epoxides on reactivity compared to butadiene epoxides: Biological significance.
B. Golding, Manuel Abelairas-Edesa, Rowena Tilbury, Joanna Wilson +5 more
2022Chemico-Biological Interactions4 citations Open access
Semantic Scholar
Detection of 1,N6-etheno-2'-deoxyadenosine and 3,N4-etheno-2'-deoxycytidine occurring endogenously in DNA.
W. P. Watson, J. Aston, T. Barlow, A. E. Crane +2 more
1999IARC scientific publications4 citations
Semantic Scholar
WEIGHING UP THE RISKS
W. P. Watson, B. Golding
19984 citations
Semantic Scholar

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