Hiroshi Yuita

Most-cited papers

1. Paradoxical association of TET loss of function with genome-wide DNA hypomethylation

   Isaac F. López-Moyado, Ageliki Tsagaratou, Hiroshi Yuita, Hyungseok Seo +4 more

   2019Proceedings of the National Academy of Sciences of the United States of America111 citations Open access

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2. Dysregulation of the TET family of epigenetic regulators in hematopoietic malignancies.

   C. Lio, Hiroshi Yuita, A. Rao

   2019Blood104 citations Open access

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3. Discovery of CS-0777: A Potent, Selective, and Orally Active S1P1 Agonist.

   T. Nishi, Shojiro Miyazaki, T. Takemoto, Keisuke Suzuki +14 more

   2011ACS Medicinal Chemistry Letters48 citations Open access

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4. Retardation of removal of radiation-induced apoptotic cells in developing neural tubes in macrophage galactose-type C-type lectin-1-deficient mouse embryos.

   Hiroshi Yuita, M. Tsuiji, Yuki Tajika, Y. Matsumoto +3 more

   2005Glycobiology35 citations Open access

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5. Discovery of CS-2100, a potent, orally active and S1P3-sparing S1P1 agonist.

   Tsuyoshi Nakamura, Masayoshi Asano, Y. Sekiguchi, Yumiko Mizuno +16 more

   2012Bioorganic & Medicinal Chemistry Letters22 citations Open access

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6. Component of Caramel Food Coloring, THI, Causes Lymphopenia Indirectly via a Key Metabolic Intermediate.

   Mamoru Ohtoyo, Nobuo Machinaga, R. Inoue, Katsunobu Hagihara +11 more

   2016Cell Chemical Biology18 citations Open access

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7. Inducible disruption of Tet genes results in myeloid malignancy, readthrough transcription, and a heterochromatin-to-euchromatin switch

   Hiroshi Yuita, Isaac F. López-Moyado, Hyeongmin Jeong, A. X. Cheng +6 more

   2023Proceedings of the National Academy of Sciences of the United States of America15 citations Open access

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8. Synthesis and evaluation of CS-2100, a potent, orally active and S1P(3)- sparing S1P(1) agonist.

   Tsuyoshi Nakamura, Masayoshi Asano, Y. Sekiguchi, Yumiko Mizuno +17 more

   2012European journal of medicinal chemistry15 citations Open access

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9. Novel Antibody Exerts Antitumor Effect through Downregulation of CD147 and Activation of Multiple Stress Signals

   Keisuke Fukuchi, Kayoko Nanai, Hiroshi Yuita, Chikako Maru +22 more

   2022Journal of Oncology9 citations Open access

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10. Synthesis and SAR of 1,3-thiazolyl thiophene and pyridine derivatives as potent, orally active and S1P₃-sparing S1P₁ agonists.

    Masayoshi Asano, Tsuyoshi Nakamura, Y. Sekiguchi, Yumiko Mizuno +18 more

    2012Bioorganic & Medicinal Chemistry Letters8 citations Open access

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11. Abstract B127: Novel anti-CD147 antibody DS-1471a exerts antitumor effect in hepatocellular carcinoma Patient Derived Xenograft models and its efficacy correlates with the expression of CD147

    Hiroshi Yuita, R. Nakamura, Jun Tsukada, Hideo Yukinaga +2 more

    2023Molecular Cancer Therapeutics1 citations

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12. Preclinical evaluation and mechanistic analysis of antitumor effects of the novel anti-CD147 antibody DS-1471a in liver cancer models

    Hiroshi Yuita, Sadanori Watanabe, Jun Tsukada, Yoshikazu Johmura +9 more

    2026Investigational new drugs0 citations Open access

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13. Evaluation of species difference in peripheral lymphocyte reduction effect of CS‐0777, a sphingosine 1‐phosphate receptor modulator, based on a pharmacokinetic/pharmacodynamic model analysis

    Shin‐ichi Inaba, M. Goto, Kaoru Tanaka-Takanaka, Hisako Tanaka +8 more

    2016Biopharmaceutics & drug disposition0 citations

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