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E. Kharasch · SciRah

Researcher profile · Semantic Scholar

E. Kharasch

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E. Kharasch — researcher profile on SciRah

h-index: 76
Works: 478
Citations: 20K

Most-cited papers

Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2D6, OPRM1, and COMT genotype and select opioid therapy
K. Crews, Andrew A. Monte, R. Huddart, K. Caudle +17 more
2021Clinical pharmacology and therapy391 citations Open access
Semantic Scholar
Metal-organic Framework Encapsulation Preserves the Bioactivity of Protein Therapeutics
Cong-Zhou Wang, G. Sudlow, Zhe-Yu Wang, Sisi Cao +6 more
2018Advanced Healthcare Materials78 citations Open access
Semantic Scholar
Intraoperative methadone in same-day ambulatory surgery: A randomized, double-blinded, dose-finding pilot study
H. Komen, L. Brunt, E. Deych, Jane Blood +1 more
2019Anesthesia and Analgesia76 citations Open access
Semantic Scholar
Opioid-free anesthesia: Time to regain our balance
E. Kharasch, J. Clark
2021Anesthesiology72 citations Open access
Semantic Scholar
Prolonged ketamine infusion modulates limbic connectivity and induces sustained remission of treatment-resistant depression
J. Siegel, B. Palanca, B. Ances, E. Kharasch +6 more
2021Psychopharmacology61 citations Open access
Semantic Scholar
Opioids and public health: The prescription opioid ecosystem and need for improved management
E. Kharasch, J. Clark, Jerome M. Adams
2021Anesthesiology58 citations Open access
Semantic Scholar
Perioperative gabapentinoids: Deflating the bubble
E. Kharasch, J. Clark, S. Kheterpal
2020Anesthesiology58 citations Open access
Semantic Scholar
Efavirenz Metabolism: Influence of Polymorphic CYP2B6 Variants and Stereochemistry
Pan-Fen Wang, Alicia Neiner, E. Kharasch
2019Drug Metabolism And Disposition57 citations Open access
Semantic Scholar
Gold Nanorod Size-Dependent Fluorescence Enhancement for Ultrasensitive Fluoroimmunoassays.
Chao Liang, Jing-Yi Luan, Zhe-Yu Wang, Qi-Sheng Jiang +7 more
2021ACS Applied Materials and Interfaces53 citations
Semantic Scholar
Rational Perioperative Opioid Management in the Era of the Opioid Crisis.
E. Kharasch, Michael J. Avram, J. Clark
2020Anesthesiology47 citations Open access
Semantic Scholar
Peer Review Matters: Research Quality and the Public Trust.
E. Kharasch, M. Avram, J. Clark, A. Davidson +5 more
2021Anesthesiology46 citations Open access
Semantic Scholar
Environmental Stability of Plasmonic Biosensors Based on Natural versus Artificial Antibody
Jing-Yi Luan, Ting Xu, J. Cashin, J. Morrissey +2 more
2018Analytical Chemistry36 citations Open access
Semantic Scholar
Intraoperative Methadone in Next-day Discharge Outpatient Surgery: A Randomized, Double-Blinded, Dose-Finding Pilot Study
E. Kharasch, L. Brunt, Jane Blood, H. Komen
2023Anesthesiology33 citations
Semantic Scholar
Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2B6 Genotype and Methadone Therapy
Katherine M. Robinson, Seenae Eum, Z. Desta, R. Tyndale +13 more
2024Clinical pharmacology and therapy29 citations Open access
Semantic Scholar
Morphine and Hydromorphone Effects, Side Effects and Variability – a Crossover Study in Human Volunteers
Konrad Meissner, A. Dahan, E. Olofsen, Christine Göpfert +3 more
2023Anesthesiology23 citations Open access
Semantic Scholar
Nicotine oxidation by genetic variants of CYP2B6 and in human brain microsomes
A. J. Bloom, Pan-Fen Wang, E. Kharasch
2019Pharmacology Research & Perspectives21 citations Open access
Semantic Scholar
Authorship and Publication Matters: Credit and Credibility
E. Kharasch, M. Avram, B. Bateman, J. Clark +8 more
2021Anesthesiology20 citations Open access
Semantic Scholar
Opioid Sensitivity in Children with and without Obstructive Sleep Apnea
Michael C. Montana, Lindsay L Juriga, Anshuman Sharma, E. Kharasch
2019Anesthesiology20 citations Open access
Semantic Scholar
Toward precision prescribing for methadone: Determinants of methadone deposition
A. Talal, Yuxin Ding, C. Venuto, Lindsay M Chakan +6 more
2020PLoS ONE19 citations Open access
Semantic Scholar
Bioplasmonic paper-based assay for perilipin-2 non-invasively detects renal cancer
Rong Hu, G. Rohit, Zhe-Yu Wang, Cong-Zhou Wang +4 more
2019Kidney International19 citations Open access
Semantic Scholar
Stereoselective Bupropion Hydroxylation by Cytochrome P450 CYP2B6 and Cytochrome P450 Oxidoreductase Genetic Variants
Pan-Fen Wang, Alicia Neiner, E. Kharasch
2020Drug Metabolism And Disposition18 citations Open access
Semantic Scholar
Methadone disposition: Implementing lessons learned
E. Kharasch, D. Greenblatt
2019Journal of clinical pharmacology18 citations Open access
Semantic Scholar
Low-dose augmentation with buprenorphine increases emotional reactivity but not reward activity in treatment resistant mid- and late-life depression
Che-Min Lin, H. Karim, M. Peciña, H. Aizenstein +6 more
2019NeuroImage: Clinical17 citations Open access
Semantic Scholar
Bioequivalance and therapeutic equivalence of generic and brand bupropion in adults with major depression: A randomized clinical trial
E. Kharasch, Alicia Neiner, Kristin Kraus, Jane Blood +4 more
2019Clinical pharmacology and therapy16 citations Open access
Semantic Scholar
The metabotropic glutamate receptor 5 negative allosteric modulator fenobam: pharmacokinetics, side effects, and analgesic effects in healthy human subjects
L. Cavallone, Michael C. Montana, K. Frey, D. Kallogjeri +5 more
2019Pain15 citations Open access
Semantic Scholar
Single-Dose Intraoperative Methadone for Pain Management in Pediatric Tonsillectomy: A Randomized Double Blind Clinical Trial
L. Einhorn, J. Hoang, Jong Ok La, E. Kharasch
2024Anesthesiology14 citations
Semantic Scholar
Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2D6, OPRM1, and COMT genotype and select opioid therapy
K. Crews, Andrew A. Monte, R. Huddart, K. Caudle +19 more
202014 citations
Semantic Scholar
Persistent Postoperative Opioid Use: Perception, Progress, and Promise.
E. Kharasch, J. Clark
2020Anesthesiology14 citations Open access
Semantic Scholar
Intraoperative methadone and postoperative anesthesia care unit outcomes: A retrospective cohort analysis
E. Kharasch
2024Anesthesiology12 citations
Semantic Scholar
Methadone pharmacogenetics in vitro and in vivo: Metabolism by CYP2B6 polymorphic variants and genetic variability in pediatric disposition
Pan-Fen Wang, Anshuman Sharma, Michael C. Montana, Alicia Neiner +5 more
2022British Journal of Clinical Pharmacology12 citations Open access
Semantic Scholar
Methadone and ketamine: Boosting benefits and still more to learn
E. Kharasch, J. Clark
2021Anesthesiology12 citations Open access
Semantic Scholar
Novel Coronavirus 2019 and Anesthesiology
E. Kharasch, Yandong Jiang
2020Anesthesiology12 citations Open access
Semantic Scholar
Observations and Observational Research.
E. Kharasch
2019Anesthesiology11 citations
Semantic Scholar
Intraoperative Methadone Administration Is Not Associated With an Increase in Perioperative Use of Naloxone: A Retrospective Study
Sarah Lumsden, E. Kharasch, B. Speer, Andrzej P Kwater +2 more
2024Anesthesia and Analgesia10 citations
Semantic Scholar
St. John’s Wort Influence on Intravenous Fentanyl Pharmacokinetics, Pharmacodynamics and Clinical Effects. A Randomized Clinical Trial.
Michael J. Loughren, E. Kharasch, Megan C. Kelton-Rehkopf, K. Syrjala +1 more
2019Anesthesiology10 citations Open access
Semantic Scholar
Reporting Laboratory and Animal Research in ANESTHESIOLOGY: The Importance of Sex as a Biologic Variable.
L. Vutskits, J. Clark, E. Kharasch
2019Anesthesiology9 citations
Semantic Scholar
Methadone and Enhanced Recovery After Surgery: Concepts and Protocols
V. Ramaiah, E. Kharasch
2024Anesthesia and Analgesia8 citations Open access
Semantic Scholar
An investigation of the potential clinical utility of critical slowing down as an early warning sign for recurrence of depression.
N. Tonge, J. P. Miller, E. Kharasch, E. Lenze +1 more
2023Journal of Behavior Therapy and Experimental Psychiatry8 citations Open access
Semantic Scholar
Opioid sensitivity in treated and untreated obstructive sleep apnoea: a prospective cohort study.
Michael C. Montana, Michael McLeland, Marilee Fisher, Lindsay Juriga +2 more
2023British Journal of Anaesthesia8 citations
Semantic Scholar
Scientific Integrity and Misconduct-Yet Again.
E. Kharasch
2021Anesthesiology8 citations
Semantic Scholar
Natural Products Inhibition of Cytochrome P450 2B6 Activity and Methadone Metabolism
Pan-Fen Wang, Yan-Ming Yang, V. Patel, Alicia Neiner +1 more
2023Drug Metabolism And Disposition7 citations
Semantic Scholar
Stereoselective Steady‐State Disposition and Bioequivalence of Brand and Generic Bupropion in Adults
E. Kharasch, Alicia Neiner, Kristin Kraus, Jane Blood +3 more
2020Clinical pharmacology and therapy7 citations
Semantic Scholar
Plasma and cerebrospinal fluid pharmacokinetics of ondansetron in humans
Manting Chiang, K. Frey, Chris C. Lee, E. Kharasch +6 more
2020British Journal of Clinical Pharmacology7 citations Open access
Semantic Scholar
Combined Pecto-intercostal Fascial Plane and Rectus Sheath Blocks Versus Local Infiltration for Pain Management Following Pediatric Cardiac Surgery: A Randomized Clinical Trial.
L. Einhorn, E. Kharasch, J. Lim, M. Fuller +4 more
2025Anesthesia and Analgesia6 citations
Semantic Scholar
Uncertainty and Certainty.
E. Kharasch
2020Anesthesiology6 citations
Semantic Scholar
Intraoperative methadone administration for total mastectomy: A single center retrospective study
J. Cata, Yusuf Zaidi, J. Guerra-Londono, E. Kharasch +6 more
2024Journal of clinical anesthesia5 citations Open access
Semantic Scholar
Modeling adult COX‐2 cerebrospinal fluid pharmacokinetics to inform pediatric investigation
J. Hannam, K. Murto, B. Anderson, G. Dembo +1 more
2022Paediatric anaesthesia5 citations Open access
Semantic Scholar
The Nine Lives of Ketamine: From CI‐581 to Present Day Clinical Application—Commentary on Domino et al.
E. Kharasch
2025Clinical pharmacology and therapy4 citations
Semantic Scholar
Pharmacogenetic Influence on Stereoselective Steady-State Disposition of Bupropion
E. Kharasch, E. Lenze
2024Drug Metabolism And Disposition4 citations Open access
Semantic Scholar
Methadone metabolism and cytochrome P450 polymorphisms: a systematic review and meta-analysis
Seenae Eum, Nicholas P Vernacchia, N. Doughty, Sahar Mehrzad +3 more
2024Expert Opinion on Drug Metabolism & Toxicology4 citations
Semantic Scholar

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