Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

L. Maile · SciRah

Researcher profile · Semantic Scholar

L. Maile

Share profile

L. Maile — researcher profile on SciRah

h-index: 32
Works: 81
Citations: 2,527

Most-cited papers

Interaction between Insulin-Like Growth Factor-I Receptor and αVβ3 Integrin Linked Signaling Pathways: Cellular Responses to Changes in Multiple Signaling Inputs
D. Clemmons, L. Maile
2005112 citations Open access
Semantic Scholar
Reduced preovulatory granulosa cell steroidogenesis in women with endometriosis.
C. Harlow, D. Cahill, L. Maile, W. M. Talbot +3 more
1996Journal of Clinical Endocrinology and Metabolism111 citations
Semantic Scholar
Regulation of Insulin-like Growth Factor I Receptor Dephosphorylation by SHPS-1 and the Tyrosine Phosphatase SHP-2*
L. Maile, D. Clemmons
2002Journal of Biological Chemistry103 citations Open access
Semantic Scholar
Insulin-like growth factor binding protein (IGFBP) proteolysis: occurrence, identification, role and regulation.
L. Maile, J. Holly
1999Growth Hormone & IGF Research93 citations
Semantic Scholar
Minireview: Integral membrane proteins that function coordinately with the insulin-like growth factor I receptor to regulate intracellular signaling.
D. Clemmons, L. Maile
2003Endocrinology84 citations Open access
Semantic Scholar
Insulin-Like Growth Factor (IGF) Binding Protein 2 Functions Coordinately with Receptor Protein Tyrosine Phosphatase β and the IGF-I Receptor To Regulate IGF-I-Stimulated Signaling
Xin-Chun Shen, G. Xi, L. Maile, C. Wai +2 more
2012Molecular and Cellular Biology81 citations Open access
Semantic Scholar
Ovarian Dysfunction in Endometriosis-Associated and Unexplained Infertility
D. Cahill, P. Wardle, L. Maile, C. Harlow +1 more
1997Journal of Assisted Reproduction and Genetics75 citations Open access
Semantic Scholar
The alphaVbeta3 integrin regulates insulin-like growth factor I (IGF-I) receptor phosphorylation by altering the rate of recruitment of the Src-homology 2-containing phosphotyrosine phosphatase-2 to the activated IGF-I receptor.
L. Maile, D. Clemmons
2002Endocrinology74 citations Open access
Semantic Scholar
Planning for Burn Disasters: What Can We Learn from One Hundred Years of History?: 1.
M. Roldan, R. Maile, C. Barnes, L. Maile +2 more
200670 citations
Semantic Scholar
Role of SHPS-1 in the regulation of insulin-like growth factor I-stimulated Shc and mitogen-activated protein kinase activation in vascular smooth muscle cells.
Y. Ling, L. Maile, J. Lieskovská, J. Badley-Clarke +1 more
2005Molecular Biology of the Cell70 citations Open access
Semantic Scholar
Insulin-like Growth Factor-I Stimulates Shc-dependent Phosphatidylinositol 3-Kinase Activation via Grb2-associated p85 in Vascular Smooth Muscle Cells*
Yashwanth Radhakrishnan, L. Maile, Y. Ling, L. Graves +1 more
2008Journal of Biological Chemistry66 citations Open access
Semantic Scholar
Hyperglycemia alters the responsiveness of smooth muscle cells to insulin-like growth factor-I.
L. Maile, B. Capps, Y. Ling, G. Xi +1 more
2007Endocrinology66 citations
Semantic Scholar
Tyrosine Phosphorylation of the β3-Subunit of the αVβ3 Integrin Is Required for Membrane Association of the Tyrosine Phosphatase SHP-2 and Its Further Recruitment to the Insulin-Like Growth Factor I Receptor
Y. Ling, L. Maile, D. Clemmons
200366 citations Open access
Semantic Scholar
Hyperglycemia Enhances IGF-I–Stimulated Src Activation via Increasing Nox4-Derived Reactive Oxygen Species in a PKCζ-Dependent Manner in Vascular Smooth Muscle Cells
G. Xi, Xin-Chun Shen, L. Maile, C. Wai +2 more
2011Diabetes64 citations Open access
Semantic Scholar
The association between integrin-associated protein and SHPS-1 regulates insulin-like growth factor-I receptor signaling in vascular smooth muscle cells.
L. Maile, J. Badley-Clarke, D. Clemmons
2003Molecular Biology of the Cell63 citations Open access
Semantic Scholar
Pituitary-ovarian dysfunction as a cause for endometriosis-associated and unexplained infertility.
D. Cahill, P. Wardle, L. Maile, C. Harlow +1 more
1995Human Reproduction58 citations
Semantic Scholar
Antibiotic treatment based on seminal cultures from asymptomatic male partners in in-vitro fertilization is unnecessary and may be detrimental.
N. Liversedge, Julian M. Jenkins, S. D. Keay, E. A. McLaughlin +4 more
1996Human Reproduction55 citations
Semantic Scholar
DOK1 Mediates SHP-2 Binding to the αVβ3 Integrin and Thereby Regulates Insulin-like Growth Factor I Signaling in Cultured Vascular Smooth Muscle Cells*
Y. Ling, L. Maile, J. Badley-Clarke, D. Clemmons
2005Journal of Biological Chemistry54 citations Open access
Semantic Scholar
IGF-I activation of the AKT pathway is impaired in visceral but not subcutaneous preadipocytes from obese subjects.
Kelly Cleveland-Donovan, L. Maile, W. Tsiaras, T. Tchkonia +2 more
2010Endocrinology50 citations Open access
Semantic Scholar
Insulin-like Growth Factor I Increases (cid:1) V (cid:2) 3 Affinity by Increasing the Amount of Integrin-associated Protein That Is Associated with Non-raft Domains of the Cellular Membrane*
L. Maile, Yumi Imai, J. Clarke, D. Clemmons
200250 citations
Semantic Scholar
Blocking ligand occupancy of the αVβ3 integrin inhibits the development of nephropathy in diabetic pigs.
L. Maile, W. H. Busby, K. Gollahon, W. Flowers +9 more
2014Endocrinology49 citations Open access
Semantic Scholar
An essential role for the association of CD47 to SHPS-1 in skeletal remodeling
L. Maile, Victoria E. Demambro, C. Wai, A. Aday +4 more
2011Journal of Bone and Mineral Research49 citations Open access
Semantic Scholar
Role of the integrin αVβ3 in mediating increased smooth muscle cell responsiveness to IGF-I in response to hyperglycemic stress
D. Clemmons, L. Maile, Y. Ling, J. Yarber +1 more
200749 citations Open access
Semantic Scholar
Integrin-Associated Protein Binding Domain of Thrombospondin-1 Enhances Insulin-Like Growth Factor-I Receptor Signaling in Vascular Smooth Muscle Cells
L. Maile, D. Clemmons
2003Circulation Research49 citations Open access
Semantic Scholar
Insulin-like growth factor-i signaling in smooth muscle cells is regulated by ligand binding to the 177CYDMKTTC184 sequence of the β3-subunit of αVβ3
L. Maile, W. H. Busby, Kevin R Sitko, B. Capps +3 more
200646 citations Open access
Semantic Scholar
Insulin‐like growth factor‐binding protein‐2 is required for osteoclast differentiation
Victoria E. Demambro, L. Maile, C. Wai, M. Kawai +3 more
2012Journal of Bone and Mineral Research44 citations Open access
Semantic Scholar
The heparin-binding domains of IGFBP-2 mediate its inhibitory effect on preadipocyte differentiation and fat development in male mice.
G. Xi, Melissa A Solum, C. Wai, L. Maile +2 more
2013Endocrinology41 citations Open access
Semantic Scholar
A Monoclonal Antibody Against αVβ3 Integrin Inhibits Development of Atherosclerotic Lesions in Diabetic Pigs
L. Maile, W. H. Busby, T. Nichols, D. Bellinger +4 more
2010Science Translational Medicine38 citations Open access
Semantic Scholar
The heparin binding domain of vitronectin is the region that is required to enhance insulin-like growth factor-I signaling.
L. Maile, W. H. Busby, Kevin R Sitko, B. Capps +4 more
2006Molecular Endocrinology37 citations Open access
Semantic Scholar
The role of cell surface attachment and proteolysis in the insulin-like growth factor (IGF)-independent effects of IGF-binding protein-3 on apoptosis in breast epithelial cells.
L. Maile, Zahidah P. Gill, C. Perks, Jeffrey M. P. Holly
1999Endocrinology36 citations Open access
Semantic Scholar
Glucose regulation of integrin-associated protein cleavage controls the response of vascular smooth muscle cells to insulin-like growth factor-I.
L. Maile, B. Capps, Emily C. Miller, L. Allen +3 more
2008Molecular Endocrinology33 citations Open access
Semantic Scholar
Integrin-Associated Protein Association With Src Homology 2 Domain Containing Tyrosine Phosphatase Substrate 1 Regulates IGF-I Signaling In Vivo
L. Maile, B. Capps, Emily C. Miller, A. Aday +1 more
2008Diabetes33 citations Open access
Semantic Scholar
Aldosterone enhances IGF-I-mediated signaling and biological function in vascular smooth muscle cells.
T. Cascella, Yashwanth Radhakrishnan, L. Maile, W. H. Busby +3 more
2010Endocrinology32 citations Open access
Semantic Scholar
Structural analysis of the role β3 subunit of the αVβ3 integrin in IGF-I signaling
L. Maile, J. Badley-Clarke, D. Clemmons
200130 citations
Semantic Scholar
Insulin-like Growth Factor-I-stimulated Insulin Receptor Substrate-1 Negatively Regulates Src Homology 2 Domain-containing Protein-tyrosine Phosphatase Substrate-1 Function in Vascular Smooth Muscle Cells*
Yashwanth Radhakrishnan, W. H. Busby, Xin-Chun Shen, L. Maile +1 more
2010Journal of Biological Chemistry29 citations Open access
Semantic Scholar
Tyrosine phosphorylation of the beta3-subunit of the alphaVbeta3 integrin is required for embrane association of the tyrosine phosphatase SHP-2 and its further recruitment to the insulin-like growth factor I receptor.
Y. Ling, L. Maile, D. Clemmons
2003Molecular Endocrinology29 citations
Semantic Scholar
Alterations in insulin-like growth factor binding protein-3 proteolysis and complex formation in the arthritic joint.
E. J. Whellams, L. Maile, Janet K. Fernihough, M. E. J. Billingham +1 more
2000Journal of Endocrinology29 citations Open access
Semantic Scholar
Recruitment of the tyrosine phosphatase Src homology 2 domain tyrosine phosphatase-2 to the p85 subunit of phosphatidylinositol-3 (PI-3) kinase is required for insulin-like growth factor-I-dependent PI-3 kinase activation in smooth muscle cells.
Mijin Kwon, Y. Ling, L. Maile, Jane Badley-Clark +1 more
2006Endocrinology27 citations
Semantic Scholar
Blocking αVβ3 Integrin Ligand Occupancy Inhibits the Progression of Albuminuria in Diabetic Rats
L. Maile, K. Gollahon, C. Wai, P. Dunbar +2 more
2014Journal of Diabetes Research26 citations Open access
Semantic Scholar
Regulation of igf-I signaling in retinal endothelial cells by hyperglycemia.
Emily C. Miller, B. Capps, Ravi R Sanghani, D. Clemmons +1 more
2007Investigative Ophthalmology and Visual Science26 citations Open access
Semantic Scholar
Structural analysis of the role of the beta 3 subunit of the alpha V beta 3 integrin in IGF-I signaling.
L. Maile, Jane Badley-Clarke, David R. Clemmons
2001Journal of Cell Science26 citations
Semantic Scholar
Igf-I signaling in response to hyperglycemia and the development of diabetic complications.
D. Clemmons, L. Maile, G. Xi, Xin-Chun Shen +1 more
2011Current Diabetes Reviews25 citations
Semantic Scholar
Hyperglycemia-induced p66shc inhibits insulin-like growth factor I-dependent cell survival via impairment of Src kinase-mediated phosphoinositide-3 kinase/AKT activation in vascular smooth muscle cells.
G. Xi, Xin-Chun Shen, Yashwanth Radhakrishnan, L. Maile +1 more
2010Endocrinology21 citations Open access
Semantic Scholar
Active and inhibitory components of the insulin-like growth factor binding protein-3 protease system in adult serum, interstitial, and synovial fluid.
L. Maile, Su Xu, Sian C. Cwyfan-Hughes, Janet K. Fernihough +2 more
1998Endocrinology21 citations Open access
Semantic Scholar
Role of the integrin alphaVbeta3 in mediating increased smooth muscle cell responsiveness to IGF-I in response to hyperglycemic stress.
D. Clemmons, L. Maile, Y. Ling, J. Yarber +1 more
2007Growth Hormone & IGF Research20 citations
Semantic Scholar
Glucose Regulation of Thrombospondin and Its Role in the Modulation of Smooth Muscle Cell Proliferation
L. Maile, L. Allen, Christopher F. Hanzaker, K. Gollahon +2 more
2010International Journal of Experimental Diabetes Research19 citations Open access
Semantic Scholar
Interaction between insulin-like growth factor-I receptor and alphaVbeta3 integrin linked signaling pathways: cellular responses to changes in multiple signaling inputs.
D. Clemmons, L. Maile
2005Molecular Endocrinology18 citations
Semantic Scholar
IGF-I stimulates cooperative interaction between the IGF-I receptor and CSK homologous kinase that regulates SHPS-1 phosphorylation in vascular smooth muscle cells.
Yashwanth Radhakrishnan, Xin-Chun Shen, L. Maile, G. Xi +1 more
2011Molecular Endocrinology17 citations Open access
Semantic Scholar
Glucose-oxidized low-density lipoproteins enhance insulin-like growth factor I-stimulated smooth muscle cell proliferation by inhibiting integrin-associated protein cleavage.
L. Allen, B. Capps, Emily C. Miller, D. Clemmons +1 more
2009Endocrinology17 citations Open access
Semantic Scholar
Modulation of integrin antagonist signaling by ligand binding of the heparin binding domain of vitronectin to the αVβ3 integrin
L. Maile, A. Aday, W. Busby, Ravi R Sanghani +2 more
2008Journal of Cellular Biochemistry17 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

D. Clemmons×37
Invite
D. Clemmons — researcher profile on SciRah
Y. Ling×10
Invite
Y. Ling — researcher profile on SciRah
W. H. Busby×9
Invite
W. H. Busby — researcher profile on SciRah
B. Capps×8
Invite
B. Capps — researcher profile on SciRah

×7

Invite

G. Xi — researcher profile on SciRah

Xin-Chun Shen×6

Invite

Xin-Chun Shen — researcher profile on SciRah

Invite

C. Wai — researcher profile on SciRah

J. Badley-Clarke×6

Invite

J. Badley-Clarke — researcher profile on SciRah

Yashwanth Radhakrishnan×6

Invite

Yashwanth Radhakrishnan — researcher profile on SciRah

Invite

K. Gollahon — researcher profile on SciRah

Invite

A. Aday — researcher profile on SciRah

Emily C. Miller×4

Invite

Emily C. Miller — researcher profile on SciRah