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E. Hammond · SciRah

Researcher profile · Semantic Scholar

E. Hammond

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E. Hammond — researcher profile on SciRah

h-index: 47
Works: 153
Citations: 9,509

Most-cited papers

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652
D. Klionsky, K. Abdelmohsen, A. Abe, M. Abedin +496 more
20161,544 citations Open access
Semantic Scholar
Ultra-High Dose Rate (FLASH) Radiotherapy: Silver Bullet or Fool's Gold?
Joseph D. Wilson, E. Hammond, G. Higgins, K. Petersson
2020Frontiers in Oncology430 citations Open access
Semantic Scholar
The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia
Thomas M. Ashton, E. Fokas, L. Kunz-Schughart, L. Folkes +10 more
2016Nature Communications229 citations Open access
Semantic Scholar
UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α
Y. Goto, L. Zeng, C. Yeom, Yu-Xi Zhu +17 more
2015Nature Communications217 citations Open access
Semantic Scholar
Targeting ATR in DNA damage response and cancer therapeutics.
E. Fokas, R. Prevo, E. Hammond, T. Brunner +2 more
2014Cancer Treatment Reviews186 citations
Semantic Scholar
A novel method for autophagy detection in primary cells
Kanchan Phadwal, J. Alegre-Abarrategui, A. S. Watson, Luke R. G. Pike +6 more
2012Autophagy153 citations Open access
Semantic Scholar
Hypoxia-induced p53 modulates both apoptosis and radiosensitivity via AKT.
K. Leszczynska, I. Foskolou, A. Abraham, S. Anbalagan +6 more
2015Journal of Clinical Investigation134 citations Open access
Semantic Scholar
Replication stress drives constitutive activation of the DNA damage response and radioresistance in glioblastoma stem-like cells
R. Carruthers, S. Ahmed, Shaliny Ramachandran, K. Strathdee +9 more
2018Cancer Research133 citations Open access
Semantic Scholar
Clinical Advances of Hypoxia-Activated Prodrugs in Combination With Radiation Therapy.
Ishna N. Mistry, Matthew Thomas, Ewen D. D. Calder, S. Conway +1 more
2017International Journal of Radiation Oncology, Biology, Physics129 citations Open access
Semantic Scholar
Optimization of 3,5-Dimethylisoxazole Derivatives as Potent Bromodomain Ligands
D. Hewings, O. Fedorov, P. Filippakopoulos, Sarah Martin +13 more
2013Journal of Medicinal Chemistry122 citations Open access
Semantic Scholar
Replication Stress and Chromatin Context Link ATM Activation to a Role in DNA Replication
M. Olcina, I. Foskolou, S. Anbalagan, Joana M. Senra +4 more
2013Molecules and Cells115 citations Open access
Semantic Scholar
Cyclic Hypoxia: An Update on Its Characteristics, Methods to Measure It and Biological Implications in Cancer
Samuel B Bader, M. Dewhirst, E. Hammond
2020Cancers95 citations Open access
Semantic Scholar
Aberrant IDH3α expression promotes malignant tumor growth by inducing HIF-1-mediated metabolic reprogramming and angiogenesis
L. Zeng, A. Morinibu, Minoru Kobayashi, Yu-Xi Zhu +12 more
2014Oncogene93 citations Open access
Semantic Scholar
Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication
I. Foskolou, Christian Jorgensen, K. Leszczynska, M. Olcina +7 more
2017Molecules and Cells92 citations Open access
Semantic Scholar
HPV, hypoxia and radiation response in head and neck cancer.
E. Göttgens, C. Ostheimer, P. Span, J. Bussink +1 more
2018British Journal of Radiology87 citations Open access
Semantic Scholar
RASSF1A-LATS1 signalling stabilises replication forks by restricting CDK2-mediated phosphorylation of BRCA2
Dafni-Eleftheria Pefani, Robert Latusek, Isabel M. Pires, A. Grawenda +6 more
2014Nature Cell Biology82 citations Open access
Semantic Scholar
UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization
R. Nakashima, Y. Goto, S. Koyasu, Minoru Kobayashi +5 more
2017Scientific Reports77 citations Open access
Semantic Scholar
Design, synthesis and evaluation of molecularly targeted hypoxia-activated prodrugs
Liam J. O’Connor, Cindy Cázares-Körner, Jaideep Saha, Charles N. G. Evans +3 more
2016Nature Protocols69 citations Open access
Semantic Scholar
CYP450 Enzymes Effect Oxygen-Dependent Reduction of Azide-Based Fluorogenic Dyes
Liam J. O’Connor, Ishna N. Mistry, Sarah L. Collins, L. Folkes +3 more
2016ACS Central Science65 citations Open access
Semantic Scholar
CH-01 is a Hypoxia-Activated Prodrug That Sensitizes Cells to Hypoxia/Reoxygenation Through Inhibition of Chk1 and Aurora A
Cindy Cázares-Körner, Isabel M. Pires, I. D. Swallow, Samuel C. Grayer +5 more
2013ACS Chemical Biology56 citations Open access
Semantic Scholar
Selective modulation by PARP-1 of HIF-1α-recruitment to chromatin during hypoxia is required for tumor adaptation to hypoxic conditions
J. M. Martí, A. García-Díaz, Daniel Delgado-Bellido, F. O'Valle +12 more
2021Redox Biology55 citations Open access
Semantic Scholar
Challenges to DNA replication in hypoxic conditions
Natalie Ng, K. Purshouse, I. Foskolou, M. Olcina +1 more
2018The FEBS Journal51 citations
Semantic Scholar
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
D. Klionsky, K. Abdelmohsen, A. Abe, J. Abedin +496 more
201650 citations Open access
Semantic Scholar
LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis
C. Yeom, L. Zeng, Y. Goto, A. Morinibu +10 more
2016OncoTarget49 citations Open access
Semantic Scholar
Epigenetic Therapy for Solid Tumors: Highlighting the Impact of Tumor Hypoxia
Shaliny Ramachandran, J. Ient, E. Göttgens, A. Krieg +1 more
2015Genes49 citations Open access
Semantic Scholar
Preclinical testing of an Atr inhibitor demonstrates improved response to standard therapies for esophageal cancer
K. Leszczynska, Greg Dobrynin, R. E. Leslie, J. Ient +6 more
2016Radiotherapy and Oncology48 citations Open access
Semantic Scholar
Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter
P. Wing, P. J. Liu, J. M. Harris, A. Magrì +19 more
2021Journal of Hepatology47 citations Open access
Semantic Scholar
Inhibition of CD4/CDK6 enhances radiosensitivity of HPV negative head and neck squamous cell carcinomas.
E. Göttgens, J. Bussink, K. Leszczynska, H. Peters +2 more
2019International Journal of Radiation Oncology, Biology, Physics46 citations
Semantic Scholar
KDM4A regulates HIF-1 levels through H3K9me3
G. Dobrynin, T. McAllister, K. Leszczynska, Shaliny Ramachandran +3 more
2017Scientific Reports44 citations Open access
Semantic Scholar
Hypoxia Potentiates the Radiation-Sensitizing Effect of Olaparib in Human Non-Small Cell Lung Cancer Xenografts by Contextual Synthetic Lethality
Yan-Yan Jiang, T. Verbiest, A. Devery, S. Bokobza +4 more
2016International Journal of Radiation Oncology, Biology, Physics44 citations Open access
Semantic Scholar
Links between the unfolded protein response and the DNA damage response in hypoxia: a systematic review
Hannah Bolland, Tiffany S Ma, S. Ramlee, Kristijan Ramadan +1 more
2021Biochemical Society Transactions39 citations Open access
Semantic Scholar
ATM activation in hypoxia - causes and consequences
M. Olcina, R. Grand, E. Hammond
2014Molecular & Cellular Oncology38 citations Open access
Semantic Scholar
Hypoxia-induced SETX links replication stress with the unfolded protein response
Shaliny Ramachandran, Tiffany S Ma, Jon Griffin, Natalie Ng +9 more
2020Nature Communications37 citations Open access
Semantic Scholar
Two Color Imaging of Different Hypoxia Levels in Cancer Cells
A. Wallabregue, Hannah Bolland, S. Faulkner, E. Hammond +1 more
2023Journal of the American Chemical Society36 citations Open access
Semantic Scholar
Use of the xCELLigence system for real-time analysis of changes in cellular motility and adhesion in physiological conditions.
Simon F. Scrace, E. O'Neill, E. Hammond, Isabel M. Pires
2013Methods in molecular biology36 citations
Semantic Scholar
Radiosensitisation in vivo by histone deacetylase inhibition with no increase in early normal tissue radiation toxicity
B. Groselj, Jia-Ling Ruan, H. Scott, Jessica Gorrill +10 more
2017Molecular Cancer Therapeutics35 citations Open access
Semantic Scholar
Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor
Anna Skwarska, Ewen D. D. Calder, Deborah Sneddon, Hannah Bolland +6 more
2021Cell Chemical Biology33 citations Open access
Semantic Scholar
The Role of the HIF-1α Transcription Factor in Increased Cell Division at Physiological Oxygen Tensions
S. Carrera, Joana M. Senra, Maria I. Acosta, M. Althubiti +3 more
2014PLoS ONE33 citations Open access
Semantic Scholar
Tumor Microenvironment and Cellular Stress
C. Koumenis, E. Hammond, A. Giaccia
2014Advances in Experimental Medicine and Biology32 citations
Semantic Scholar
Small-molecule Polθ inhibitors provide safe and effective tumor radiosensitization in preclinical models
G. Rodriguez-Berriguete, M. Ranzani, R. Prevo, R. Puliyadi +20 more
2022bioRxiv29 citations Open access
Semantic Scholar
Replication catastrophe induced by cyclic hypoxia leads to increased APOBEC3B activity
Samuel B Bader, Tiffany S Ma, Charlotte J Simpson, Jia-Chen Liang +4 more
2021Nucleic Acids Research29 citations Open access
Semantic Scholar
Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain
M. Brand, J. Clayton, M. Moroglu, M. Schiedel +24 more
2020Journal of Medicinal Chemistry24 citations Open access
Semantic Scholar
Radiation and ATM inhibition: the heart of the matter.
E. Hammond, R. Muschel
2014Journal of Clinical Investigation22 citations Open access
Semantic Scholar
SPINK1 as a plasma marker for tumor hypoxia and a therapeutic target for radiosensitization
Tatsuya Suwa, Minoru Kobayashi, Yukari Shirai, Jin-Min Nam +7 more
2021JCI Insight21 citations Open access
Semantic Scholar
BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability.
Laura E. Jennings, M. Schiedel, D. Hewings, S. Picaud +19 more
2018Bioorganic & Medicinal Chemistry21 citations Open access
Semantic Scholar
WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer
F. Poujade, Aarren J. Mannion, Nicholas Brittain, Andrew Theodosi +6 more
2018British Journal of Cancer21 citations Open access
Semantic Scholar
Oxali(IV)Fluors: Fluorescence Responsive Oxaliplatin(IV) Complexes Identify a Hypoxia-Dependent Reduction in Cancer Cells
Marie H C Boulet, Hannah Bolland, E. Hammond, Adam C. Sedgwick
2023Journal of the American Chemical Society20 citations Open access
Semantic Scholar
HIF-1α-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion
Isabel M. Pires, N. Blokland, A. Broos, F. Poujade +5 more
2014Cancer Biology & Therapy20 citations Open access
Semantic Scholar
Mechanisms and consequences of ATMIN repression in hypoxic conditions: roles for p53 and HIF-1
K. Leszczynska, E. Göttgens, D. Biasoli, M. Olcina +5 more
2016Scientific Reports19 citations Open access
Semantic Scholar
Efficient synthesis of 2-nitroimidazole derivatives and the bioreductive clinical candidate Evofosfamide (TH-302)
Liam J. O’Connor, Cindy Cázares-Körner, Jaideep Saha, Charles N. G. Evans +3 more
201519 citations
Semantic Scholar

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