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Mitsue Nishiyama · SciRah

Researcher profile · Semantic Scholar

Mitsue Nishiyama

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Mitsue Nishiyama — researcher profile on SciRah

h-index: 12
Works: 45
Citations: 388

Most-cited papers

Validation and standardization of DNA extraction and library construction methods for metagenomics-based human fecal microbiome measurements
D. Tourlousse, Koji Narita, Takamasa Miura, M. Sakamoto +31 more
2021Microbiome89 citations Open access
Semantic Scholar
A microarray analysis of gnotobiotic mice indicating that microbial exposure during the neonatal period plays an essential role in immune system development
Masahiro Yamamoto, R. Yamaguchi, K. Munakata, Kiyoe Takashima +8 more
2012BMC Genomics47 citations Open access
Semantic Scholar
Possible involvement of the transient receptor potential vanilloid type 1 channel in postoperative adhesive obstruction and its prevention by a kampo (traditional Japanese) medicine, daikenchuto.
Yohei Tokita, Masahiro Yamamoto, K. Satoh, Mitsue Nishiyama +3 more
2011Journal of Pharmacological Sciences37 citations Open access
Semantic Scholar
Increase of Akkermansia muciniphila by a Diet Containing Japanese Traditional Medicine Bofutsushosan in a Mouse Model of Non-Alcoholic Fatty Liver Disease
Mitsue Nishiyama, Nobuhiro Ohtake, A. Kaneko, Naoko Tsuchiya +7 more
2020Nutrients28 citations Open access
Semantic Scholar
Time-, Sex-, and Dose-Dependent Alterations of the Gut Microbiota by Consumption of Dietary Daikenchuto (TU-100)
J. Miyoshi, Kentaro Nobutani, M. Musch, Daina L. Ringus +5 more
2018Evidence-Based Complementary and Alternative Medicine23 citations Open access
Semantic Scholar
Impact of Gut Microbiota on the Pharmacokinetics of Glycyrrhizic Acid in Yokukansan, a Kampo Medicine.
T. Ishida, Kohei Jobu, K. Kawada, Shumpei Morisawa +10 more
2022Biological and Pharmaceutical Bulletin21 citations Open access
Semantic Scholar
Intestinal, portal, and peripheral profiles of daikenchuto (TU-100)'s active ingredients after oral administration
J. Watanabe, Noriko Kaifuchi, H. Kushida, Takashi Matsumoto +4 more
2015Pharmacology Research & Perspectives20 citations Open access
Semantic Scholar
Intron retention as a new pre-symptomatic marker of aging and its recovery to the normal state by a traditional Japanese multi-herbal medicine
N. Okada, K. Oshima, Y. Iwasaki, A. Maruko +11 more
2020bioRxiv17 citations Open access
Semantic Scholar
Associations between intestinal microbiota, fecal properties, and dietary fiber conditions: The Japanese traditional medicine Junchoto ameliorates dietary fiber deficit-induced constipation with F/B ratio alteration in rats.
T. Oshiro, Y. Harada, Kunitsugu Kubota, Daichi Sadatomi +3 more
2022Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie14 citations Open access
Semantic Scholar
Microarray analysis on germfree mice elucidates the primary target of a traditional Japanese medicine juzentaihoto: acceleration of IFN-α response via affecting the ISGF3-IRF7 signaling cascade
K. Munakata, Kiyoe Takashima, Mitsue Nishiyama, N. Asano +5 more
2012BMC Genomics14 citations Open access
Semantic Scholar
Predicting Inchinkoto efficacy, in patients with obstructive jaundice associated with malignant tumors, through pharmacomicrobiomics.
Hiromasa Yamashita, Mitsue Nishiyama, Katsuya Ohbuchi, H. Kanno +6 more
2021Pharmacological Research13 citations Open access
Semantic Scholar
Involvement of Interleukin-17A-Induced Hypercontractility of Intestinal Smooth Muscle Cells in Persistent Gut Motor Dysfunction
H. Akiho, Yohei Tokita, Kazuhiko Nakamura, K. Satoh +8 more
2014PLoS ONE13 citations Open access
Semantic Scholar
Integrated analysis of effect of daisaikoto, a traditional Japanese medicine, on the metabolome and gut microbiome in a mouse model of nonalcoholic fatty liver disease.
Shiori Ishizawa, A. Nishi, Noriko Kaifuchi, C. Shimobori +8 more
2022Gene9 citations Open access
Semantic Scholar
Microbiome biomarkers associated with the gut contraction response elicited by the Japanese traditional medicine daikenchuto.
Y. Wada, Mitsue Nishiyama, Hideaki Uehara, Kazuko Sato +5 more
2022Gene8 citations Open access
Semantic Scholar
Distinct effects of TU-100 (daikenchuto) on long-lasting dysbiosis in the small intestine in patients with colorectal cancer and inflammatory bowel disease.
T. Kono, T. Maejima, Yusuke Ono, Takahiro Itoh +7 more
2022Gene7 citations
Semantic Scholar
Saireito, a Japanese herbal medicine, alleviates leaky gut associated with antibiotic-induced dysbiosis in mice
S. Ozaka, A. Sonoda, Shimpei Ariki, Mizuki Minata +18 more
2022PLoS ONE5 citations Open access
Semantic Scholar
Daikenchuto (TU‐100) alters murine hepatic and intestinal drug metabolizing enzymes in an in vivo dietary model: effects of gender and withdrawal
Kentaro Nobutani, J. Miyoshi, M. Musch, Mitsue Nishiyama +7 more
2017Pharmacology Research & Perspectives4 citations Open access
Semantic Scholar
Transient receptor potential vanilloid 1-immunoreactive signals in murine enteric glial cells
Masahiro Yamamoto, Mitsue Nishiyama, S. Iizuka, Shigeaki Suzuki +3 more
2016World Journal of Gastroenterology4 citations Open access
Semantic Scholar
Effect of daikenchuto (TU-100) on carcinogenesis in non-alcoholic steatohepatitis.
S. Yamada, Y. Morine, S. Imura, T. Ikemoto +6 more
2023Journal of Medical Investigation3 citations Open access
Semantic Scholar
A potential pathway that links intron retention with the physiological recovery by a Japanese herbal medicine
Norihiro Okada, Kenshiro Oshima, A. Maruko, Trieu-Duc Vu +5 more
2023bioRxiv2 citations Open access
Semantic Scholar
Combinability of Animal Data in Relative Potency Estimations
H. Uehara, K. Satoh, Nagisa Komokata, Yohei Tokita +5 more
20162 citations Open access
Semantic Scholar
64 Role of Acetylcholine and Serotonin Receptors in the Maintenance of Muscle Hypercontractility in a Murine Model of Post-Inflammatory Irritable Bowel Syndrome
H. Akiho, H. Murao, H. Ogino, K. Kanayama +11 more
20082 citations
Semantic Scholar
Bofutsushosan (Fangfengtongshengsan) improves early stages of NASH via the gut–liver axis in diabetes-induced NASH model mice
Mitsue Nishiyama, Shiori Ishizawa, A. Nishi, A. Taketomi +1 more
2024Pharmacological Research - Modern Chinese Medicine1 citations Open access
Semantic Scholar
Data of RNA-seq transcriptomes of liver, bone, heart, kidney and blood in klotho mice at a pre-symptomatic state and the effect of a traditional Japanese multi-herbal medicine, juzentaihoto
Norihiro Okada, K. Oshima, Y. Iwasaki, A. Maruko +11 more
2022Data in Brief1 citations Open access
Semantic Scholar
Impact of Daikenchuto (TU-100) on the early postoperative period in duodenal-jejunal bypass.
Shohei Okikawa, H. Kashihara, Y. Morine, M. Shimada +7 more
2021Journal of Medical Investigation1 citations Open access
Semantic Scholar
Japanese Traditional Medicine Bofutsushosan Increased Akkermaisia Muciniphila in Gut Microbiota and Improved Non-Alcoholic Fatty Liver Disease in Obese Mice
Mitsue Nishiyama, Masahiro Yamamoto, Nobuhiro Otake, S. Iizuka +3 more
20171 citations
Semantic Scholar
Microarray analysis on germfree mice elucidates the primary target of a traditional Japanese medicine juzentaihoto: acceleration of IFN-α response via affecting the ISGF3-IRF7 signaling cascade
K. Munakata, Kiyoe Takashima, Mitsue Nishiyama, Naoko Asano +5 more
2012BMC Genomics1 citations Open access
Semantic Scholar
W1928 Modulation of Smooth Muscle Cell Contractility by TH1/TH2 Cytokines in Gut Hyper-Contractility in a Murine Model of T Cell-Mediated Persistent Gut Motor Dysfunction
Yohei Tokita, K. Satoh, Mitsue Nishiyama, Ryota Ikemura +10 more
20101 citations
Semantic Scholar
Sa373 BOFUTSUSHOSAN, A TRADITIONAL JAPANESE MEDICINE, MAINTAINS THE GUT MICROBIOME AND AMELIORATES PROGRESSION OF LIVER DISORDER IN DIABETES INDUCED NASH MODEL MICE
T. Kono, Shiori Ishizawa, Mitsue Nishiyama, Yoshiki Ikeda +1 more
20210 citations
Semantic Scholar
Best-practice evaluation and guidance for human metagenomic studies
D. Tourlousse, Koji Narita, Takamasa Miura, M. Sakamoto +31 more
20210 citations Open access
Semantic Scholar
Tu1932 THE DOSE-RESPONSE RELATION BETWEEN A FIBER DIET AND THE GUT MICROBIOTA FOR THE ALLEVIATION OF CONSTIPATION: USEFULNESS OF THE JAPANESE TRADITIONAL MEDICINE MASHININGAN IN RATS RECEIVING A FIBER-FREE DIET
T. Oshiro, Y. Harada, Kunitsugu Kubota, Daichi Sadatomi +4 more
20200 citations
Semantic Scholar
Sa1562 NON-ALCOHOLIC STEATOHEPATITIS-ASSOCIATED ALTERATION OF INFLAMMATORY LIPID MEDIATORS, PRIMARY METABOLITES AND MICROBIOME IN A STAM MOUSE MODEL, AND THERAPEUTIC POTENTIAL OF A JAPANESE TRADITIONAL MEDICINE, DAISAIKOTO.
A. Nishi, Noriko Kaifuchi, Shiori Ishizawa, Miwa Nahata +10 more
20200 citations
Semantic Scholar
Mo2045 INVOLVEMENT OF THE GUT MICROBIOTA IN THE ALLEVIATION OF CONSTIPATION ON TREATMENT WITH THE JAPANESE TRADITIONAL MEDICINE JUNCHOTO
Y. Harada, T. Oshiro, Kunitsugu Kubota, Daichi Sadatomi +4 more
20200 citations
Semantic Scholar
Su1087 – Change of Gut Microbiome After Treatment with the Traditional Japanese Medicine Daisaikoto is Associated with Improved Liver Steatosis in a Non-Alcoholic Fatty Liver Mouse Model
Shiori Ishizawa, Miwa Nahata, C. Yamada, A. Nishi +6 more
2019Gastroenterology0 citations
Semantic Scholar
Su1640 – Persistent Improvement in Chronic Constipation with the Traditional Japanese Medicine Mashiningan Involves Altered Gut Microbiota Composition in Fiber-Free Diet-Treated Rats
Y. Harada, Kunitsugu Kubota, Daichi Sadatomi, T. Oshiro +3 more
2019Gastroenterology0 citations Open access
Semantic Scholar
Sa1190 - Healing two Wounds with One Kiss: Traditional Herbal Medicine Kamikihito Improves Psychological and Gastrointestinal Symptoms in Patients with Chronic Constipation Syndrome
Keiko K Lee, A. Kobayashi, Hiroyuki Kobayashi, A. Hu +7 more
20180 citations
Semantic Scholar
Profiles of Small Intestinal Microbiota: Possible Relationships with IBD and Abdominal Bloating
Mitsue Nishiyama, T. Kono, Yusuke Mizukami, A. Maemoto +4 more
20170 citations
Semantic Scholar
Su1216 Fecal Microbiome Analysis Revealed that the Japanese Traditional Medicine Daikenchuto (TU-100) Increases Lactic Acid Bacteria and Intraluminal Butyrate Content in Mice
Mitsue Nishiyama, Katsuya Ohbuchi, C. Miyagi, Masahiro Yamamoto +6 more
20160 citations
Semantic Scholar
Assessment of Intrasub ject Parallelism in Ex Vivo Bioassay Using Two One-Sided Tolerance Limits
H. Uehara, K. Satoh, Nagisa Komokata, Yohei Tokita +5 more
20160 citations Open access
Semantic Scholar
Sa1701 Profiles of Gut Microbiota and Production of Short Chain Fatty Acids in Guinea Pigs
Mitsue Nishiyama, Katsuya Ohbuchi, C. Miyagi, Nagisa Komokata +5 more
20160 citations
Semantic Scholar
Tu1722 Small Intestinal Microbiota of Colonic IBD Patients May Give Rise to an Altered Gut Microenvironment Enabling Selective Enrichment of Bacterial Populations: Implications of Microbiome Analysis on Ileal Effluent
T. Kono, Mitsue Nishiyama, A. Kaneko, Masahiro Yamamoto +3 more
20130 citations Open access
Semantic Scholar
13 IL-17 is Critically Involved in the Gut Hypermotility Following Resolution of T-Cell Mediated Inflammation
K. Satoh, Yohei Tokita, Mitsue Nishiyama, H. Akiho +4 more
20120 citations Open access
Semantic Scholar
Tu1977 IL-17 Induces Hypercontractility in Intestinal Smooth Muscle Strips and Cells via Nf?B Signaling
Yohei Tokita, K. Satoh, Mitsue Nishiyama, H. Akiho +4 more
20120 citations Open access
Semantic Scholar
14 IL-17 Suppresses RGS4 Translocation in Primary Cultured Intestinal Smooth Muscle Cells via IκBξ Signaling: an Indication of a Mechanism of IL-17-Induced Gut Hypermotility
Mitsue Nishiyama, Yohei Tokita, K. Satoh, H. Akiho +4 more
20120 citations
Semantic Scholar
T Cell-Mediated Intestinal Inflammation Causes Gut Hypo-Motility: A Possible Involvement of IL-1β-Triggered NfκB-IκBζ-RGS4 Signaling, and the Effect of a Traditional Japanese Medicine Daikenchuto (Dkt, TU-100)
Yohei Tokita, K. Satoh, Mitsue Nishiyama, Ryota Ikemura +9 more
20110 citations Open access
Semantic Scholar

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Masahiro Yamamoto×26
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Masahiro Yamamoto — researcher profile on SciRah
T. Kono×14
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T. Kono — researcher profile on SciRah
K. Satoh×11
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Yohei Tokita×10
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Yohei Tokita — researcher profile on SciRah

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A. Kaneko — researcher profile on SciRah

N. Fujitsuka×10

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A. Nishi — researcher profile on SciRah

Shiori Ishizawa×8

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Shiori Ishizawa — researcher profile on SciRah

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S. Iizuka — researcher profile on SciRah

Katsuya Ohbuchi×7

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Katsuya Ohbuchi — researcher profile on SciRah

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H. Akiho — researcher profile on SciRah

Kazuhiko Nakamura×7

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Kazuhiko Nakamura — researcher profile on SciRah