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T. Birngruber · SciRah

Researcher profile · Semantic Scholar

T. Birngruber

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T. Birngruber — researcher profile on SciRah

h-index: 18
Works: 95
Citations: 1,176

Most-cited papers

The Impact of Prolonged Inflammation on Wound Healing
J. Holzer-Geissler, S. Schwingenschuh, M. Zacharias, Johanna Einsiedler +9 more
2022Biomedicines187 citations Open access
Semantic Scholar
Enhanced doxorubicin delivery to the brain administered through glutathione PEGylated liposomal doxorubicin (2B3-101) as compared with generic Caelyx,(®)/Doxil(®)--a cerebral open flow microperfusion pilot study.
T. Birngruber, R. Raml, W. Gladdines, Christina Gatschelhofer +6 more
2014Journal of Pharmacy and Science104 citations
Semantic Scholar
Open Flow Microperfusion as a Dermal Pharmacokinetic Approach to Evaluate Topical Bioequivalence
M. Bodenlenz, K. Tiffner, R. Raml, T. Augustin +8 more
2016Clinical Pharmacokinetics89 citations Open access
Semantic Scholar
Extracellular vesicles in human skin: cross-talk from senescent fibroblasts to keratinocytes by miRNAs.
Lucia Terlecki-Zaniewicz, V. Pils, M. Bobbili, I. Lämmermann +18 more
2019Journal of Investigative Dermatology84 citations Open access
Semantic Scholar
Assessment of Blood-Brain Barrier Function and the Neuroinflammatory Response in the Rat Brain by Using Cerebral Open Flow Microperfusion (cOFM)
Arijit Ghosh, T. Birngruber, W. Sattler, Thomas Kroath +3 more
2014PLoS ONE60 citations Open access
Semantic Scholar
Delivery of antiseptic solutions by a bacterial cellulose wound dressing: Uptake, release and antibacterial efficacy of octenidine and povidone-iodine.
Ives Bernardelli de Mattos, S. Nischwitz, A. Tuca, F. Groeber-Becker +5 more
2020Burns51 citations
Semantic Scholar
A novel human ex-vivo burn model and the local cooling effect of a bacterial nanocellulose-based wound dressing.
J. Holzer, K. Tiffner, S. Kainz, P. Reisenegger +8 more
2020Burns51 citations Open access
Semantic Scholar
Clinical applicability of dOFM devices for dermal sampling
M. Bodenlenz, B. Aigner, C. Dragatin, L. Liebenberger +11 more
2013Skin research and technology47 citations
Semantic Scholar
A novel human ex vivo skin model to study early local responses to burn injuries
E. Hofmann, J. Fink, Anita Eberl, Eva-Maria Prugger +8 more
2021Scientific Reports43 citations Open access
Semantic Scholar
Cerebral open flow microperfusion: A new in vivo technique for continuous measurement of substance transport across the intact blood–brain barrier
T. Birngruber, Arijit Ghosh, Veronica Perez-Yarza, Thomas Kroath +3 more
2013Clinical and Experimental Pharmacology and Physiology39 citations
Semantic Scholar
Uptake of PHMB in a bacterial nanocellulose-based wound dressing: A feasible clinical procedure.
I. B. de Mattos, J. Holzer, A. Tuca, F. Groeber-Becker +5 more
2019Burns32 citations
Semantic Scholar
Time-resolved hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood–brain barrier in leptin resistant mice
M. Kleinert, P. Kotzbeck, T. Altendorfer-Kroath, T. Birngruber +2 more
2018Molecular Metabolism26 citations Open access
Semantic Scholar
Enhanced Absorption of Insulin Aspart as the Result of a Dispersed Injection Strategy Tested in a Randomized Trial in Type 1 Diabetic Patients
J. Mader, T. Birngruber, S. Korsatko, Sigrid Deller +6 more
2013Diabetes Care24 citations Open access
Semantic Scholar
Cerebral open flow microperfusion (cOFM) an innovative interface to brain tissue.
T. Birngruber, F. Sinner
2016Drug Discovery Today : Technologies19 citations
Semantic Scholar
Open Flow Microperfusion: An Alternative Method to Microdialysis?
T. Pieber, T. Birngruber, M. Bodenlenz, C. Höfferer +3 more
201319 citations
Semantic Scholar
ImmUniverse Consortium: Multi-omics integrative approach in personalized medicine for immune-mediated inflammatory diseases
S. Vetrano, G. Bouma, R. Benschop, T. Birngruber +20 more
2022Frontiers in Immunology18 citations Open access
Semantic Scholar
Variability of Skin Pharmacokinetic Data: Insights from a Topical Bioequivalence Study Using Dermal Open Flow Microperfusion
M. Bodenlenz, T. Augustin, T. Birngruber, K. Tiffner +5 more
2020Pharmaceutical Research18 citations Open access
Semantic Scholar
Evaluating Dermal Pharmacokinetics and Pharmacodymanic Effect of Soft Topical PDE4 Inhibitors: Open Flow Microperfusion and Skin Biopsies
S. Eirefelt, Joanna Hummer, Line Hollesen Basse, M. Bertelsen +6 more
2020Pharmaceutical Research18 citations
Semantic Scholar
Long-Term Implanted cOFM Probe Causes Minimal Tissue Reaction in the Brain
T. Birngruber, Arijit Ghosh, S. Hochmeister, M. Asslaber +3 more
2014PLoS ONE18 citations Open access
Semantic Scholar
Filamentous Aggregation of Sequestosome-1/p62 in Brain Neurons and Neuroepithelial Cells upon Tyr-Cre-Mediated Deletion of the Autophagy Gene Atg7
S. Sukseree, L. Laszlo, F. Gruber, Sophie Bergmann +10 more
2018Molecular Neurobiology17 citations Open access
Semantic Scholar
miRNAs as Regulators of the Early Local Response to Burn Injuries
I. Foessl, C. Haudum, I. Vidakovic, R. Prassl +7 more
2021International Journal of Molecular Sciences16 citations Open access
Semantic Scholar
Dermal open flow microperfusion for PK-based clinical bioequivalence studies of topical drug products
T. Birngruber, K. Tiffner, S. Mautner, F. Sinner
2022Frontiers in Pharmacology13 citations Open access
Semantic Scholar
OFM-recirculation and OFM-suction: advanced in-vivo open flow microperfusion (OFM) methods for direct and absolute quantification of albumin in interstitial fluid
Joanna Hummer, S. Schwingenschuh, R. Raml, Beate Boulgaropoulos +4 more
2020Biomedical engineering and physics express13 citations Open access
Semantic Scholar
Optimization of topical formulations using a combination of in vitro methods to quantify the transdermal passive diffusion of drugs.
Joanna Hummer, T. Birngruber, F. Sinner, L. Page +5 more
2022International journal of pharmaceutics12 citations
Semantic Scholar
Characterizing Cutaneous Drug Delivery Using Open-Flow Microperfusion and Mass Spectrometry Imaging.
Anne Mette Handler, S. Eirefelt, M. Lambert, Fredrik Johansson +9 more
2021Molecular Pharmaceutics12 citations Open access
Semantic Scholar
Comparison of cerebral Open Flow Microperfusion and Microdialysis when sampling small lipophilic and small hydrophilic substances.
T. Altendorfer-Kroath, Denise Schimek, Anita Eberl, G. Rauter +4 more
2019Journal of Neuroscience Methods12 citations
Semantic Scholar
Cerebral Open Flow Microperfusion to Monitor Drug Transport Across the Blood‐Brain Barrier
Joanna Hummer, T. Altendorfer-Kroath, T. Birngruber
2019Current Protocols in Pharmacology11 citations
Semantic Scholar
Chronic intrahypothalamic rather than subcutaneous liraglutide treatment reduces body weight gain and stimulates the melanocortin receptor system
K. Kaineder, T. Birngruber, G. Rauter, B. Obermüller +8 more
2017International Journal of Obesity11 citations Open access
Semantic Scholar
Targeted nanoliposomes to improve enzyme replacement therapy of Fabry disease
Judit Tomsen-Melero, Marc Moltó-Abad, Josep Merlo-Mas, Z. V. Díaz-Riascos +22 more
2024Science Advances10 citations Open access
Semantic Scholar
Comparative Study of Dermal Pharmacokinetics Between Topical Drugs Using Open Flow Microperfusion in a Pig Model
M. Bodenlenz, Thean Yeoh, Gabriel Berstein, Shibin Mathew +11 more
2023Pharmaceutical Research10 citations Open access
Semantic Scholar
Detailed pharmacokinetic characterization of advanced topical acyclovir formulations with IVPT and in-vivo Open Flow Microperfusion.
Gerd Schwagerle, M. J. Sharp, A. Parr, Denise Schimek +2 more
2023International journal of pharmaceutics9 citations Open access
Semantic Scholar
Opportunities of Topical Drug Products in a Changing Dermatological Landscape.
Wen-Kai Hsiao, Michael E. Herbig, John M. Newsam, Ulrich Gottwald +3 more
2024European Journal of Pharmaceutical Sciences8 citations Open access
Semantic Scholar
Characterization of Inflammatory Mediators and Metabolome in Interstitial Fluid Collected with Dermal Open Flow Microperfusion before and at the End of Dupilumab Treatment in Atopic Dermatitis
Fernanda Monedeiro, B. Ehall, K. Tiffner, Anita Eberl +10 more
2024Journal of Proteome Research7 citations
Semantic Scholar
Cutaneous Pharmacokinetics-Based Bioequivalence: A Clinical Dermal Open Flow Microperfusion Verification Study Using Lidocaine and Prilocaine Combination Topical Products.
K. Tiffner, T. Ramezanli, Beate Boulgaropoulos, T. Birngruber +6 more
2024European Journal of Pharmaceutical Sciences7 citations Open access
Semantic Scholar
LC/MS/MS analyses of open-flow microperfusion samples quantify eicosanoids in a rat model of skin inflammation[S]
Cornelia Pipper, Natalie Bordag, B. Reiter, Kyriakos D. Economides +5 more
2019Journal of Lipid Research7 citations Open access
Semantic Scholar
Quantification of Basal Insulin Peglispro and Human Insulin in Adipose Tissue Interstitial Fluid by Open-Flow Microperfusion
K. Tiffner, Beate Boulgaropoulos, C. Höfferer, T. Birngruber +7 more
2017Diabetes Technology & Therapeutics7 citations
Semantic Scholar
Topical Delivery Systems Effectively Transport Analgesics to Areas of Localized Pain via Direct Diffusion
T. Birngruber, K. Vought, S. Schwingenschuh, P. Reisenegger +2 more
2023Pharmaceutics5 citations Open access
Semantic Scholar
In vivo monitoring of brain pharmacokinetics and pharmacodynamics with cerebral open flow microperfusion
T. Altendorfer-Kroath, Joanna Hummer, T. Birngruber
2023Biopharmaceutics & drug disposition5 citations Open access
Semantic Scholar
Small volume rapid equilibrium dialysis (RED) measures effects of interstitial parameters on the protein-bound fraction of topical drugs.
L. Wiltschko, E. Roblegg, R. Raml, T. Birngruber
2023Journal of Pharmaceutical and Biomedical Analysis5 citations Open access
Semantic Scholar
Topical application of haemoglobin: a safety study.
J. Holzer, T. Birngruber, S. Mautner, A. Graff +1 more
2019Journal of Wound Care5 citations
Semantic Scholar
Insulin Distribution in Human Adipose Tissue via a Novel Insulin Infusion Catheter
T. Altendorfer-Kroath, S. Schwingenschuh, P. K. Schøndorff, M. Heschel +2 more
2019Diabetes Technology & Therapeutics4 citations
Semantic Scholar
Quantification of the Therapeutic Antibody Ocrelizumab in Mouse Brain Interstitial Fluid Using Cerebral Open Flow Microperfusion and Simultaneous Monitoring of the Blood–Brain Barrier Integrity
T. Altendorfer-Kroath, Joanna Hummer, Denise Kollmann, Beate Boulgaropoulos +2 more
2023Pharmaceutics3 citations Open access
Semantic Scholar
Atraumatic Access to Human Glioblastoma in a Xenograft Animal Model by Cerebral Open Flow Microperfusion.
T. Altendorfer-Kroath, M. Asslaber, Joanna Hummer, Beate Boulgaropoulos +4 more
2023Journal of Neuroscience Methods3 citations
Semantic Scholar
646 Impact of Inflammation on Wound Healing
H. Luze, J. Holzer, S. Kainz, P. Reisenegger +6 more
20203 citations
Semantic Scholar
Erratum to: Open Flow Microperfusion as a Dermal Pharmacokinetic Approach to Evaluate Topical Bioequivalence
M. Bodenlenz, K. Tiffner, R. Raml, T. Augustin +8 more
2016Clinical Pharmacokinetics3 citations Open access
Semantic Scholar
Certified dOFM sampling devices provide access to target tissue in pharmaceutical trials
M. Bodenlenz, C. Dragatin, Christian Hoefferer, T. Birngruber +7 more
2013Biomedizinische Technik. Biomedical engineering3 citations Open access
Semantic Scholar
Advanced Online Monitoring of In Vitro Human 3D Full-Thickness Skin Equivalents
R. Schaller-Ammann, Sebastian Kress, Jürgen Feiel, Gerd Schwagerle +4 more
2022Pharmaceutics2 citations Open access
Semantic Scholar
488 Continuous sampling of immune cells in the skin by dermal open flow microperfusion
T. Birngruber, B. Prietl, M. Bodenlenz, P. Florian +5 more
20172 citations Open access
Semantic Scholar
Antimicrobial nano silver (Ag)-enabled wound dressing evaluated using open flow microperfusion: Comparison of uncoated versus hydroxyethyl cellulose-coated Ag.
I. Zanoni, S. Schwingenschuh, T. Birngruber, P. Reisenegger +11 more
2026NanoImpact1 citations Open access
Semantic Scholar
Predicting human subcutaneous bioavailability of monoclonal antibodies using an open flow microperfusion porcine model.
Gerd Schwagerle, R. Bonan, Mikolaj Milewski, Manuel Sanchez-Felix +12 more
2025Journal of Controlled Release1 citations
Semantic Scholar

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