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E. Vellenga · SciRah

Researcher profile · Semantic Scholar

E. Vellenga

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E. Vellenga — researcher profile on SciRah

h-index: 94
Works: 731
Citations: 33K

Most-cited papers

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
D. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, M. Abdellatif +496 more
2021Autophagy4,016 citations Open access
Semantic Scholar
Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes.
P. Fenaux, U. Platzbecker, G. Mufti, G. Garcia-Manero +39 more
2020New England Journal of Medicine462 citations Open access
Semantic Scholar
Definition of Iron Deficiency Based on the Gold Standard of Bone Marrow Iron Staining in Heart Failure Patients
N. Grote Beverborg, I. Klip, W. Meijers, A. Voors +11 more
2018Circulation: Heart Failure217 citations Open access
Semantic Scholar
The multifaceted role of autophagy in cancer and the microenvironment
H. Folkerts, S. Hilgendorf, E. Vellenga, E. Bremer +1 more
2018Medicinal research reviews (Print)194 citations Open access
Semantic Scholar
Bortezomib before and after high-dose therapy in myeloma: long-term results from the phase III HOVON-65/GMMG-HD4 trial
H. Goldschmidt, H. Lokhorst, Ek Mai, B. van der Holt +28 more
2018Leukemia192 citations Open access
Semantic Scholar
Azacitidine maintenance after intensive chemotherapy improves DFS in older AML patients.
G. Huls, D. Chitu, V. Havelange, M. Jongen-Lavrencic +16 more
2019Blood157 citations Open access
Semantic Scholar
Non-canonical PRC1.1 Targets Active Genes Independent of H3K27me3 and Is Essential for Leukemogenesis.
Vincent van den Boom, Henny Maat, M. Geugien, Aida Rodríguez López +11 more
2016Cell Reports156 citations Open access
Semantic Scholar
Imetelstat Achieves Meaningful and Durable Transfusion Independence in High Transfusion-Burden Patients With Lower-Risk Myelodysplastic Syndromes in a Phase II Study.
D. Steensma, P. Fenaux, K. van Eygen, A. Raza +19 more
2020Journal of Clinical Oncology103 citations Open access
Semantic Scholar
Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones.
B. D. de Boer, Janine C. M. Prick, M. Pruis, P. Keane +16 more
2018Cancer Cell99 citations Open access
Semantic Scholar
Therapeutic value of clofarabine in younger and middle-aged (18-65 years) adults with newly diagnosed AML.
B. Lowenberg, T. Pabst, J. Maertens, Y. van Norden +22 more
2017Blood98 citations Open access
Semantic Scholar
Establishing human leukemia xenograft mouse models by implanting human bone marrow-like scaffold-based niches.
A. Antonelli, W. Noort, J. Jaques, B. D. de Boer +12 more
2016Blood81 citations Open access
Semantic Scholar
Constitutive NF-κB activation in AML: Causes and treatment strategies.
M. Bosman, J. Schuringa, E. Vellenga
2016Critical reviews in oncology/hematology75 citations
Semantic Scholar
Inhibition of autophagy as treatment strategy for p53 wild type acute myeloid leukemia
H. Folkerts, S. Hilgendorf, A. Wierenga, J. Jaques +5 more
201871 citations
Semantic Scholar
Addition of lenalidomide to intensive treatment in younger and middle-aged adults with newly diagnosed AML: the HOVON-SAKK-132 trial.
B. Lowenberg, T. Pabst, J. Maertens, P. Gradowska +44 more
2021Blood Advances69 citations Open access
Semantic Scholar
Implementation of erythroid lineage analysis by flow cytometry in diagnostic models for myelodysplastic syndromes
E. Cremers, T. Westers, C. Alhan, C. Calì +15 more
2017Haematologica67 citations Open access
Semantic Scholar
The Medalist Trial: Results of a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Luspatercept to Treat Anemia in Patients with Very Low-, Low-, or Intermediate-Risk Myelodysplastic Syndromes (MDS) with Ring Sideroblasts (RS) Who Require Red Blood Cell (RBC) Transfusions
P. Fenaux, U. Platzbecker, G. Mufti, G. Garcia-Manero +35 more
2018Blood62 citations
Semantic Scholar
Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock
Maria Azkanaz, Aida Rodríguez López, B. D. de Boer, Wouter Huiting +7 more
2019eLife55 citations Open access
Semantic Scholar
Differential redox-regulation and mitochondrial dynamics in normal and leukemic hematopoietic stem cells: A potential window for leukemia therapy.
Katharina Mattes, E. Vellenga, H. Schepers
2019Critical reviews in oncology/hematology54 citations Open access
Semantic Scholar
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
D. Klionsky, K. Abdelmohsen, A. Abe, J. Abedin +496 more
201650 citations Open access
Semantic Scholar
Modeling BCR-ABL and MLL-AF9 leukemia in a human bone marrow-like scaffold-based xenograft model
P. Sontakke, M. Carretta, J. Jaques, A. Brouwers-Vos +7 more
2016Leukemia47 citations Open access
Semantic Scholar
The IL1-IL1RAP axis plays an important role in the inflammatory leukemic niche that favors acute myeloid leukemia proliferation over normal hematopoiesis
B. D. de Boer, S. Sheveleva, Katja Apelt, E. Vellenga +3 more
2020Haematologica40 citations Open access
Semantic Scholar
Early detection and evolution of preleukemic clones in therapy-related myeloid neoplasms following autologous SCT.
G. Berger, L. Kroeze, Theresia N. Koorenhof-Scheele, A. D. de Graaf +10 more
2018Blood40 citations Open access
Semantic Scholar
Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes
Guoqiang Yi, A. Wierenga, F. Petraglia, Pankaj Narang +23 more
2019Cell Reports38 citations Open access
Semantic Scholar
HIF1/2-exerted control over glycolytic gene expression is not functionally relevant for glycolysis in human leukemic stem/progenitor cells
A. Wierenga, Alan Cunningham, A. Erdem, Núria Vilaplana Lopera +7 more
2019Cancer & Metabolism38 citations Open access
Semantic Scholar
University of Groningen Studies on megakaryopoiesis in patients with myelodysplasia and idiopathic thrombocytopenic
E. Houwerzijl, N. Blom, E. Vellenga, J. D. de Wolf
201736 citations
Semantic Scholar
RUNX1 mutations enhance self-renewal and block granulocytic differentiation in human in vitro models and primary AMLs.
M. Gerritsen, Guoqiang Yi, Esther Tijchon, Jorren Kuster +3 more
2019Blood Advances33 citations Open access
Semantic Scholar
Thalidomide before and after autologous stem cell transplantation in recently diagnosed multiple myeloma (HOVON-50): long-term results from the phase 3, randomised controlled trial.
N. V. van de Donk, B. van der Holt, M. Minnema, E. Vellenga +17 more
2018The Lancet Haematology31 citations Open access
Semantic Scholar
Phase II study of carfilzomib, thalidomide, and low-dose dexamethasone as induction and consolidation in newly diagnosed, transplant eligible patients with multiple myeloma; the Carthadex trial
R. Wester, B. van der Holt, E. Asselbergs, S. Zweegman +10 more
2019Haematologica27 citations Open access
Semantic Scholar
CITED2 affects leukemic cell survival by interfering with p53 activation
Katharina Mattes, G. Berger, M. Geugien, E. Vellenga +1 more
2017Cell Death and Disease26 citations Open access
Semantic Scholar
Identification of relevant drugable targets in diffuse large B-cell lymphoma using a genome-wide unbiased CD20 guilt-by association approach
M. D. de Jong, L. Visser, G. Huls, A. Diepstra +7 more
2018PLoS ONE25 citations Open access
Semantic Scholar
Genetically engineered mesenchymal stromal cells produce IL-3 and TPO to further improve human scaffold-based xenograft models.
M. Carretta, B. D. de Boer, J. Jaques, A. Antonelli +6 more
2017Experimental Hematology25 citations Open access
Semantic Scholar
Long-term outcome of older patients with newly diagnosed de novo acute promyelocytic leukemia treated with ATRA plus anthracycline-based therapy
D. Martínez-Cuadrón, P. Montesinos, E. Vellenga, T. Bernal +18 more
2018Leukemia24 citations Open access
Semantic Scholar
Inhibition of autophagy as a treatment strategy for p53 wild-type acute myeloid leukemia
H. Folkerts, Susan Hilgendorf, A. Wierenga, J. Jaques +4 more
2017Cell Death and Disease19 citations Open access
Semantic Scholar
PET in Benign Bone Marrow Disorders.
W. van der Bruggen, A. Glaudemans, E. Vellenga, R. Slart
2017Seminars in nuclear medicine19 citations
Semantic Scholar
Hypoxia-Like Signatures Induced by BCR-ABL Potentially Alter the Glutamine Uptake for Maintaining Oxidative Phosphorylation
P. Sontakke, Katarzyna M. Koczula, J. Jaques, A. Wierenga +5 more
2016PLoS ONE19 citations Open access
Semantic Scholar
BRD3/4 inhibition and FLT3-ligand deprivation target pathways that are essential for the survival of human MLL-AF9+ leukemic cells
M. Carretta, A. Brouwers-Vos, M. Bosman, S. Horton +3 more
2017PLoS ONE17 citations Open access
Semantic Scholar
Genomic array as compared to karyotyping in myelodysplastic syndromes in a prospective clinical trial
Marian J. Stevens-Kroef, D. O. Olde Weghuis, Najat Elidrissi-Zaynoun, B. van der Reijden +15 more
2017Genes, Chromosomes and Cancer17 citations Open access
Semantic Scholar
Not type of induction therapy but consolidation with allogeneic hematopoietic cell transplantation determines outcome in older AML patients: A single center experience of 355 consecutive patients.
J. Hilberink, C. Hazenberg, E. van den Berg, A. Mulder +8 more
2019Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis16 citations Open access
Semantic Scholar
S837 TREATMENT WITH IMETELSTAT PROVIDES DURABLE TRANSFUSION INDEPENDENCE (TI) IN HEAVILY TRANSFUSED NON-DEL(5Q) LOWER RISK MDS (LR-MDS) RELAPSED/REFRACTORY (R/R) TO ERYTHROPOIESIS STIMULATING AGENTS (ESAS)
P. Fenaux, D. Steensma, K. van Eygen, A. Raza +17 more
2019HemaSphere16 citations Open access
Semantic Scholar
Clinical significance of complex karyotype at diagnosis in pediatric and adult patients with de novo acute promyelocytic leukemia treated with ATRA and chemotherapy
J. Labrador, E. Luño, E. Vellenga, S. Brunet +23 more
2018Leukemia and Lymphoma16 citations Open access
Semantic Scholar
Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia
Abhishek A. Singh, F. Petraglia, A. Nebbioso, Guoqiang Yi +27 more
2018OncoTarget15 citations Open access
Semantic Scholar
Modeling of Chronic Myeloid Leukemia: An Overview of In Vivo Murine and Human Xenograft Models
P. Sontakke, J. Jaques, E. Vellenga, J. Schuringa
2016Stem Cells International15 citations Open access
Semantic Scholar
Nuclear medicine imaging of multiple myeloma, particularly in the relapsed setting
E. D. de Waal, A. Glaudemans, C. Schröder, E. Vellenga +1 more
2016European Journal of Nuclear Medicine and Molecular Imaging15 citations Open access
Semantic Scholar
CD34+ acute myeloid leukemia cells with low levels of reactive oxygen species show increased expression of stemness genes and can be targeted by the BCL2 inhibitor venetoclax
Katharina Mattes, M. Gerritsen, H. Folkerts, M. Geugien +5 more
2019Haematologica14 citations Open access
Semantic Scholar
Peripheral blood cytopenias in the aging general population and risk of incident hematological disease and mortality.
I. V. van Zeventer, A. D. de Graaf, M. M. van der Klauw, E. Vellenga +6 more
2021Blood Advances13 citations Open access
Semantic Scholar
Phase 2 Study of Carfilzomib, Thalidomide, and Low-Dose Dexamethasone As Induction/Consolidation in Newly Diagnosed, Transplant Eligible Patients with Multiple Myeloma, the Carthadex Trial
R. Wester, B. van der Holt, E. Asselbergs, M. van Duin +11 more
201613 citations
Semantic Scholar
Inferior Outcome of Addition of the Aminopeptidase Inhibitor Tosedostat to Standard Intensive Treatment for Elderly Patients with AML and High Risk MDS
J. Janssen, B. Lowenberg, M. Manz, M. Bargetzi +42 more
2021Cancers12 citations Open access
Semantic Scholar
Clonal hematopoiesis in patients with stem cell mobilization failure: a nested case-control study
C. Hazenberg, A. D. de Graaf, René Mulder, L. Bungener +9 more
2022Blood Advances11 citations Open access
Semantic Scholar
Imetelstat Treatment Leads to Durable Transfusion Independence (TI) in RBC Transfusion-Dependent (TD), Non-Del(5q) Lower Risk MDS Relapsed/Refractory to Erythropoiesis-Stimulating Agent (ESA) Who Are Lenalidomide (LEN) and HMA Naive
D. Steensma, U. Platzbecker, K. van Eygen, A. Raza +15 more
2018Blood11 citations Open access
Semantic Scholar
Low relapse risk in poor risk AML after conditioning with 10-day decitabine, fludarabine and 2 Gray TBI prior to allogeneic hematopoietic cell transplantation
M. Cruijsen, J. Hilberink, W. van der Velden, J. Jansen +9 more
2021Bone Marrow Transplantation10 citations Open access
Semantic Scholar

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A. Mulder×9
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