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H. Arase · SciRah

Researcher profile · Semantic Scholar

H. Arase

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H. Arase — researcher profile on SciRah

h-index: 57
Works: 242
Citations: 12K

Most-cited papers

An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies
Ya-Fei Liu, W. T. Soh, J. Kishikawa, M. Hirose +32 more
2021Cell246 citations Open access
Semantic Scholar
LILRB4 signaling in leukemia cells mediates T cell suppression and tumor infiltration
Mi Deng, X. Gui, Jaehyup Kim, Li Xie +42 more
2018Nature218 citations Open access
Semantic Scholar
Blocking immunoinhibitory receptor LILRB2 reprograms tumor-associated myeloid cells and promotes antitumor immunity
Hui‐ming Chen, W. van der Touw, Yuan-Shuo A. Wang, K. Kang +15 more
2018Journal of Clinical Investigation211 citations Open access
Semantic Scholar
Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors
Fumiji Saito, Kouyuki Hirayasu, T. Satoh, Christian W. Wang +15 more
2017Nature150 citations Open access
Semantic Scholar
A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer’s disease
Penghui Zhao, Yuanzhong Xu, Lu-Lin Jiang, Xuejun Fan +10 more
2022Science Translational Medicine126 citations
Semantic Scholar
Functional and genetic diversity of leukocyte immunoglobulin-like receptor and implication for disease associations
Kouyuki Hirayasu, H. Arase
2015Journal of Human Genetics114 citations
Semantic Scholar
SARS-CoV-2 Lambda variant exhibits higher infectivity and immune resistance
I. Kimura, Y. Kosugi, Jia-Qi Wu, D. Yamasoba +13 more
2021bioRxiv96 citations Open access
Semantic Scholar
Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration
R. Watson, J. Buck, L. Levin, R. Winger +3 more
2015Journal of Experimental Medicine96 citations Open access
Semantic Scholar
SARS-CoV-2 S2–targeted vaccination elicits broadly neutralizing antibodies
K. Ng, Nikhil Faulkner, Katja Finsterbusch, Mary Y. Wu +17 more
2022Science Translational Medicine89 citations Open access
Semantic Scholar
Autoantibodies to IgG/HLA class II complexes are associated with rheumatoid arthritis susceptibility
Hui Jin, N. Arase, Kouyuki Hirayasu, M. Kohyama +19 more
2014Proceedings of the National Academy of Sciences of the United States of America72 citations Open access
Semantic Scholar
β2-Glycoprotein I/HLA class II complexes are novel autoantigens in antiphospholipid syndrome.
K. Tanimura, Hui Jin, T. Suenaga, Satoko Morikami +16 more
2015Blood70 citations Open access
Semantic Scholar
The N-terminal domain of spike glycoprotein mediates SARS-CoV-2 infection by associating with L-SIGN and DC-SIGN
W. T. Soh, Ya-Fei Liu, E. Nakayama, Chikako Ono +5 more
2020bioRxiv61 citations Open access
Semantic Scholar
LILRB3 supports acute myeloid leukemia development and regulates T-cell antitumor immune responses through the TRAF2–cFLIP–NF-κB signaling axis
Guojin Wu, Yixiang Xu, Robbie D. Schultz, Heyu Chen +10 more
2021Nature Cancer58 citations Open access
Semantic Scholar
LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions
Penghui Zhao, Yuanzhong Xu, Lu-Lin Jiang, Xuejun Fan +13 more
2022Molecular Neurodegeneration51 citations Open access
Semantic Scholar
Structural basis for RIFIN-mediated activation of LILRB1 in malaria
T. E. Harrison, Alexander M. Mørch, J. Felce, Akihito Sakoguchi +4 more
2020Nature50 citations Open access
Semantic Scholar
Antagonistic anti-LILRB1 monoclonal antibody regulates antitumor functions of natural killer cells
Heyu Chen, Yuan-Zhi Chen, Mi Deng, Samuel John +18 more
2020Journal for ImmunoTherapy of Cancer46 citations Open access
Semantic Scholar
Heme ameliorates dextran sodium sulfate-induced colitis through providing intestinal macrophages with noninflammatory profiles
H. Kayama, M. Kohyama, Daisuke Okuzaki, D. Motooka +13 more
2018Proceedings of the National Academy of Sciences of the United States of America43 citations Open access
Semantic Scholar
Microbially cleaved immunoglobulins are sensed by the innate immune receptor LILRA2
Kouyuki Hirayasu, Fumiji Saito, T. Suenaga, K. Shida +12 more
2016Nature Microbiology42 citations
Semantic Scholar
Neoself-antigens are the primary target for autoreactive T cells in human lupus.
Shunsuke Mori, M. Kohyama, Yoshiaki Yasumizu, Asa Tada +22 more
2024Cell38 citations Open access
Semantic Scholar
Discovery and engineering of an anti-TREM2 antibody to promote amyloid plaque clearance by microglia in 5XFAD mice
Penghui Zhao, Yuanzhong Xu, Xuejun Fan, Lei-Ke Li +5 more
2022mAbs38 citations Open access
Semantic Scholar
Identification of conserved SARS-CoV-2 spike epitopes that expand public cTfh clonotypes in mild COVID-19 patients
Xiu-Yuan Lu, Yuki Hosono, M. Nagae, Shigenari Ishizuka +26 more
2021Journal of Experimental Medicine36 citations Open access
Semantic Scholar
Monocyte infiltration into obese and fibrilized tissues is regulated by PILRα
M. Kohyama, Sumiko Matsuoka, K. Shida, Fuminori Sugihara +4 more
2016European Journal of Immunology35 citations Open access
Semantic Scholar
The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines
Ya-Fei Liu, N. Arase, J. Kishikawa, M. Hirose +20 more
2021bioRxiv33 citations Open access
Semantic Scholar
The Fc domain of immunoglobulin is sufficient to bridge NK cells with virally infected cells
Hong-Sheng Dai, N. Griffin, Chelsea M Bolyard, H. Mao +9 more
2017Immunity31 citations Open access
Semantic Scholar
An inhaled ACE2 decoy confers protection against SARS-CoV-2 infection in preclinical models
Emiko Urano, Yumi Itoh, Tatsuya Suzuki, Takanori Sasaki +28 more
2023Science Translational Medicine29 citations
Semantic Scholar
SARS-CoV-2 ORF8 is a viral cytokine regulating immune responses
M. Kohyama, Tatsuya Suzuki, Wataru Nakai, Chikako Ono +13 more
2022bioRxiv27 citations Open access
Semantic Scholar
Antigen-driven selection of antibodies against SSA, SSB and the centromere ‘complex’, including a novel antigen, MIS12 complex, in human salivary glands
M. Takeshita, Katsuya Suzuki, Yukari Kaneda, Humitsugu Yamane +6 more
2019Annals of the Rheumatic Diseases27 citations Open access
Semantic Scholar
SARS-CoV-2-induced humoral immunity through B cell epitope analysis in COVID-19 infected individuals
Shota Yoshida, Chikako Ono, H. Hayashi, S. Fukumoto +5 more
2021Scientific Reports26 citations Open access
Semantic Scholar
Blockade of checkpoint ILT3/LILRB4/gp49B binding to fibronectin ameliorates autoimmune disease in BXSB/Yaa mice.
Mei-Tzu Su, M. Inui, Y. Wong, M. Takahashi +11 more
2021International Immunology25 citations
Semantic Scholar
Plasmodium falciparum RIFIN is a novel ligand for inhibitory immune receptor LILRB2.
Akihito Sakoguchi, Fumiji Saito, Kouyuki Hirayasu, K. Shida +8 more
2021Biochemical and Biophysical Research Communications - BBRC24 citations
Semantic Scholar
Myeloperoxidase/HLA Class II Complexes Recognized by Autoantibodies in Microscopic Polyangiitis
Ryosuke Hiwa, K. Ohmura, N. Arase, Hui Jin +9 more
2017Arthritis & Rheumatology24 citations Open access
Semantic Scholar
Sialic Acids on Varicella-Zoster Virus Glycoprotein B Are Required for Cell-Cell Fusion*
T. Suenaga, M. Matsumoto, F. Arisawa, M. Kohyama +3 more
2015Journal of Biological Chemistry24 citations Open access
Semantic Scholar
TRIM28 Expression on Dendritic Cells Prevents Excessive T Cell Priming by Silencing Endogenous Retrovirus
S. Chikuma, Soichiro Yamanaka, So Nakagawa, M. Ueda +6 more
2021Journal of Immunology23 citations
Semantic Scholar
A TCR-like antibody against a proinsulin-containing fusion peptide ameliorates type 1 diabetes in NOD mice.
Y. Matsumoto, K. Kishida, M. Matsumoto, Sumiko Matsuoka +3 more
2020Biochemical and Biophysical Research Communications - BBRC22 citations
Semantic Scholar
The β 2‐Glycoprotein I/HLA–DR Complex As a Major Autoantibody Target in Obstetric Antiphospholipid Syndrome
K. Tanimura, S. Saito, M. Nakatsuka, T. Nagamatsu +7 more
2020Arthritis & Rheumatology21 citations Open access
Semantic Scholar
Cellular misfolded proteins rescued from degradation by MHC class II molecules are possible targets for autoimmune diseases.
N. Arase, H. Arase
2015Journal of Biochemistry (Tokyo)21 citations
Semantic Scholar
Rheumatoid Rescue of Misfolded Cellular Proteins by MHC Class II Molecules: A New Hypothesis for Autoimmune Diseases.
H. Arase
2016Advances in Immunology20 citations
Semantic Scholar
Mechanisms for Host Immune Evasion Mediated by Plasmodium falciparum-Infected Erythrocyte Surface Antigens
Akihito Sakoguchi, H. Arase
2022Frontiers in Immunology18 citations Open access
Semantic Scholar
Negative regulation of DSS-induced experimental colitis by PILRα.
K. Kishida, M. Kohyama, Y. Kurashima, Yuta Kogure +6 more
2015International Immunology18 citations
Semantic Scholar
An infectivity-enhancing site on the SARS-CoV-2 spike protein is targeted by COVID-19 patient antibodies
Ya-Fei Liu, W. T. Soh, Asa Tada, Akemi Arakawa +21 more
2020bioRxiv16 citations Open access
Semantic Scholar
Neutralizing and enhancing antibodies against SARS-CoV-2
Ya-Fei Liu, H. Arase
2022Inflammation and Regeneration15 citations Open access
Semantic Scholar
Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules
Hui Jin, K. Kishida, N. Arase, Sumiko Matsuoka +6 more
2022Science Advances14 citations Open access
Semantic Scholar
Landscape of infection enhancing antibodies in COVID-19 and healthy donors
Hendra S. Ismanto, Zichang Xu, Dianita S. Saputri, Jan Wilamowski +6 more
2022bioRxiv13 citations Open access
Semantic Scholar
Preclinical study of DNA vaccines targeting SARS-CoV-2
H. Hayashi, Jiao Sun, Y. Yanagida, Takako Ootera +24 more
2020bioRxiv13 citations Open access
Semantic Scholar
The effect of rhododendrol inhibition of NF-κB on melanocytes in the presence of tyrosinase.
N. Arase, Ling-Li Yang, A. Tanemura, Fei Yang +3 more
2016Journal of dermatological science (Amsterdam)11 citations
Semantic Scholar
Molecular mechanism of the recognition of bacterially cleaved immunoglobulin by the immune regulatory receptor LILRA2
R. Yamazaki, A. Furukawa, Kouyuki Hirayasu, K. Yumoto +3 more
2020Journal of Biological Chemistry10 citations Open access
Semantic Scholar
Cell surface-expressed Ro52/IgG/HLA-DR complex is targeted by autoantibodies in patients with inflammatory myopathies.
N. Arase, H. Tsuji, H. Takamatsu, Hui Jin +16 more
2021Journal of Autoimmunity9 citations Open access
Semantic Scholar
Anti-β2-glycoprotein I/HLA-DR antibody in infertility.
Yosuke Ono, S. Wada, H. Ota, Y. Fukushi +4 more
2023Journal of Reproductive Immunology8 citations
Semantic Scholar
Anti–Double‐Stranded DNA Antibodies Recognize DNA Presented on HLA Class II Molecules of Systemic Lupus Erythematosus Risk Alleles
H. Tsuji, K. Ohmura, Hui Jin, Ryota Naito +11 more
2021Arthritis & Rheumatology8 citations
Semantic Scholar
Genotype and phenotype analysis of patients with pediatric cutaneous mastocytosis, especially wild‐type KIT patients
N. Arase, M. Wataya-Kaneda, H. Murota, Y. Nakagawa +6 more
2020Journal of dermatology (Print)8 citations
Semantic Scholar

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