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R. Buj · SciRah

Researcher profile · Semantic Scholar

R. Buj

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R. Buj — researcher profile on SciRah

h-index: 14
Works: 44
Citations: 644

Most-cited papers

DNA methylation profiling of well‐differentiated thyroid cancer uncovers markers of recurrence free survival
V. Mančíková, R. Buj, E. Castelblanco, L. Inglada-Pérez +15 more
2014International Journal of Cancer77 citations
Semantic Scholar
Suppression of p16 alleviates the senescence-associated secretory phenotype
R. Buj, K. Leon, Marlyn A. Anguelov, K. Aird
2020bioRxiv71 citations Open access
Semantic Scholar
Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease
R. Buj, K. Aird
2018Frontiers in Endocrinology69 citations Open access
Semantic Scholar
DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A
K. Leon, R. Buj, Elizabeth M. Lesko, E. Dahl +6 more
2020bioRxiv61 citations Open access
Semantic Scholar
Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming
R. Buj, Chi-Wei Chen, E. Dahl, K. Leon +20 more
2019Cell Reports58 citations Open access
Semantic Scholar
Molecular profiling for acromegaly treatment: a validation study.
M. Puig-Domingo, J. Gil, M. Sampedro-Núñez, Mireia Jordà +19 more
2020Endocrine-Related Cancer47 citations Open access
Semantic Scholar
Increased Global DNA Hypomethylation in Distant Metastatic and Dedifferentiated Thyroid Cancer
E. N. Klein Hesselink, C. Zafón, N. Villalmanzo, C. Iglesias +12 more
2018Journal of Clinical Endocrinology and Metabolism36 citations Open access
Semantic Scholar
Targeting IDH1 as a pro-senescent therapy in high-grade serous ovarian cancer
E. Dahl, R. Buj, K. Leon, J. Newell +4 more
2019Molecular Cancer Research35 citations Open access
Semantic Scholar
DNA methylation profiling identifies PTRF/Cavin-1 as a novel tumor suppressor in Ewing sarcoma when co-expressed with caveolin-1.
Juan Huertas-Martínez, F. Court, S. Rello-Varona, D. Herrero-Martín +22 more
2017Cancer Letters30 citations
Semantic Scholar
p16: cycling off the beaten path
R. Buj, K. Aird
2019Molecular & Cellular Oncology23 citations Open access
Semantic Scholar
Kallikreins Stepwise Scoring Reveals Three Subtypes of Papillary Thyroid Cancer with Prognostic Implications
R. Buj, I. Mallona, A. Díez-Villanueva, C. Zafón +7 more
2018Thyroid19 citations
Semantic Scholar
Quantification of Unmethylated Alu (QUAlu): a tool to assess global hypomethylation in routine clinical samples
R. Buj, I. Mallona, A. Díez-Villanueva, Víctor Barrera +13 more
2016OncoTarget18 citations Open access
Semantic Scholar
Loss of p16: A Bouncer of the Immunological Surveillance?
K. Leon, N. K. Tangudu, K. Aird, R. Buj
2021Life17 citations Open access
Semantic Scholar
ATM inhibition drives metabolic adaptation via induction of macropinocytosis
Zhen-Tai Huang, Chi-Wei Chen, R. Buj, N. K. Tangudu +8 more
2020bioRxiv15 citations Open access
Semantic Scholar
ATM inhibition synergizes with fenofibrate in high grade serous ovarian cancer cells
Chi-Wei Chen, R. Buj, E. Dahl, K. Leon +1 more
2020bioRxiv12 citations Open access
Semantic Scholar
A plasmid toolkit for cloning chimeric cDNAs encoding customized fusion proteins into any Gateway destination expression vector
R. Buj, N. Iglesias, A. Planas, T. Santalucía
2013BMC Molecular Biology12 citations Open access
Semantic Scholar
Title Page Title: Simultaneous isotope dilution quantification and metabolic tracing of deoxyribonucleotides by liquid chromatography high resolution mass spectrometry Authors:
R. Kuskovsky, R. Buj, Pei-Ning Xu, S. Hofbauer +6 more
201810 citations
Semantic Scholar
αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation
Apoorva Uboveja, Zhen-Tai Huang, R. Buj, A. Amalric +18 more
2024bioRxiv8 citations Open access
Semantic Scholar
De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression
N. K. Tangudu, R. Buj, Hui Wang, Jie-Fei Wang +12 more
2023bioRxiv7 citations Open access
Semantic Scholar
Zinc availability in the tumor microenvironment dictates anti-PD1 response in CDKN2ALow tumors via increased macrophage phagocytosis
R. Buj, Aidan R. Cole, Jeff Danielson, Jimmy P. Xu +34 more
2025bioRxiv4 citations Open access
Semantic Scholar
αKG-mediated carnitine synthesis drives DNA repair via histone acetylation
Apoorva Uboveja, Baixue Yang, R. Buj, A. Amalric +35 more
2026Nature3 citations Open access
Semantic Scholar
The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming
Aidan R. Cole, R. Buj, Apoorva Uboveja, Evan Levasseur +43 more
2026Nature Aging3 citations Open access
Semantic Scholar
De Novo Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression
N. K. Tangudu, R. Buj, Hui Wang, Jie-Fei Wang +15 more
2024Cancer Research Communications3 citations Open access
Semantic Scholar
The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming
Aidan R. Cole, R. Buj, Apoorva Uboveja, Evan Levasseur +34 more
2025bioRxiv2 citations Open access
Semantic Scholar
Overexpression of oncogenic H-Ras in hTERT-immortalized and SV40-transformed human cells targets replicative and specialized DNA polymerases for depletion
Wei-chung Tsao, R. Buj, K. Aird, J. Sidorova +1 more
2021PLoS ONE2 citations Open access
Semantic Scholar
Targeting IDH1 as a pro-senescent therapy in high-grade serous ovarian cancer
E. Dahl, R. Buj, K. Leon, J. Newell +3 more
2018bioRxiv2 citations Open access
Semantic Scholar
Uracil-DNA glycosylase deficiency is associated with repressed tumor cell-intrinsic inflammatory signaling and altered sensitivity to exogenous interferons
F. Vendetti, Pinakin Pandya, Carina R. Sclafani, Sudipta Pathak +6 more
2025NAR Cancer1 citations Open access
Semantic Scholar
Deoxyuridine-rich cytoplasmic DNA antagonizes STING-dependent innate immune responses and sensitizes resistant tumors to anti-PD-L1 therapy
Pinakin Pandya, F. Vendetti, Joseph El-Ghoubaira, Sudipta Pathak +13 more
2024bioRxiv1 citations Open access
Semantic Scholar
Tumor-Associated Macrophages Expand Chemoresistant, Ovarian Cancer Stem-Like Cells
Allison C. Sharrow, Madeline Ho, Aakriti Dua, R. Buj +5 more
2023bioRxiv1 citations Open access
Semantic Scholar
ATR promotes mTORC1 activity via de novo cholesterol synthesis
N. K. Tangudu, Alexandra N. Grumet, Richard S. Fang, R. Buj +14 more
2023bioRxiv1 citations Open access
Semantic Scholar
Suppression of p16 increases nucleotide synthesis via mTORC1
R. Buj, Chi-Wei Chen, E. Dahl, K. Leon +20 more
2018bioRxiv1 citations Open access
Semantic Scholar
Abstract 3799: CDKN2ALow cancer cells outcompete macrophages for microenvironmental zinc to drive immunotherapy resistance
R. Buj, K. Aird
2025Cancer Research0 citations
Semantic Scholar
Abstract IA022: Uracil DNA glycosylase activity limits deoxyuridine contamination in genomic DNA and is essential for the type-1 interferon response in cells treated with ATR kinase inhibitors
Pinakin Pandya, F. Vendetti, Joseph Ghoubaira, Sudipta Pathak +9 more
2024Cancer Research0 citations
Semantic Scholar
Peer Review #1 of "Differential p16 expression levels in the liver, hepatocytes and hepatocellular cell lines (v0.1)"
Barbara Kramar, D. Šuput, I. Milisav, G. Angelico +200 more
20210 citations Open access
Semantic Scholar
Abstract A38: ATM inhibitor synergizes with glycolysis inhibition in ovarian cancer cells
Chi-Wei Chen, E. Dahl, K. Leon, R. Buj +1 more
20200 citations
Semantic Scholar
Oncogenic H-Ras Signaling Differentially Targets Replicative and Specialized DNA Polymerases for Depletion
Wei-chung Tsao, R. Buj, K. Aird, J. Sidorova +1 more
2020bioRxiv0 citations Open access
Semantic Scholar
Abstract 1378: Targeting the metabolic-epigenetic axis to sensitize HR-proficient ovarian cancer to PARP inhibitors
E. Dahl, K. Leon, Chi-Wei Chen, Q. Jia +3 more
2020Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
Abstract A35: Targeting the IDH1-mediated metabolic-epigenetic axis in cyclin E-high ovarian cancer
E. Dahl, R. Buj, Q. Jia, K. Leon +1 more
20200 citations
Semantic Scholar
Vestidos con memoria de forma
Elena Zapico, R. Buj, L. Peponi, A. Galisteo
20180 citations
Semantic Scholar
Abstract A40: Epigenomic profiling identifies NCRNAs as novel tumor suppressors in developmental tumors
D. Herrero-Martín, F. Court, S. Rello-Varona, Miguel Sáinz-Jaspeado +11 more
20160 citations
Semantic Scholar
Increased global DNA hypomethylation in metastatic and dedifferentiated thyroid cancer
E. N. Klein Hesselink, C. Zafón, R. Buj, N. Villalmanzo +8 more
20160 citations
Semantic Scholar
Epigenetic profiling identifies MIR10A-5 p as a putative tumor suppresor in Ewing sarcoma and rhabdomyosarcoma
David Herrero Martín, F. Court, S. Rello-Varona, Miguel Sáinz-Jaspeado +10 more
20160 citations
Semantic Scholar
Spanish molecular registry of pituitary adenomas: a multicenter, translational approach aimed at improving patient management
A. Leal-Cerro, R. Luque, L. Sanchez-Tejada, A. Ibáñez-Costa +16 more
20130 citations Open access
Semantic Scholar
Accessory pathway potentials Variable expression during anterograde pre-excitation
J. Farré, M. Fidalgo, F. Monteiro, A. Asso +7 more
19950 citations
Semantic Scholar

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