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A. Blight · SciRah

Researcher profile · Semantic Scholar

A. Blight

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A. Blight — researcher profile on SciRah

h-index: 48
Works: 114
Citations: 9,081

Most-cited papers

Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical power needed for therapeutic clinical trials
J. Fawcett, A. Curt, J. Steeves, W. Coleman +17 more
2007Spinal Cord874 citations
Semantic Scholar
Myelination in the absence of galactocerebroside and sulfatide: normal structure with abnormal function and regional instability.
T. Coetzee, N. Fujita, J. Dupree, R. Shi +3 more
1996Cell627 citations Open access
Semantic Scholar
Sustained-release oral fampridine in multiple sclerosis: a randomised, double-blind, controlled trial.
A. Goodman, T. Brown, L. Krupp, R. Schapiro +4 more
2009The Lancet525 citations
Semantic Scholar
Guidelines for the conduct of clinical trials for spinal cord injury (SCI) as developed by the ICCP panel: clinical trial outcome measures
J. Steeves, D. Lammertse, A. Curt, J. Fawcett +16 more
2007Spinal Cord525 citations
Semantic Scholar
Cellular morphology of chronic spinal cord injury in the cat: analysis of myelinated axons by line-sampling.
A. Blight
1983Neuroscience354 citations
Semantic Scholar
Morphometric analysis of experimental spinal cord injury in the cat: the relation of injury intensity to survival of myelinated axons.
A. Blight, V. Decrescito
1986Neuroscience287 citations
Semantic Scholar
Macrophages and Inflammatory Damage in Spinal Cord Injury
A. Blight
1992Journal of Neurotrauma248 citations
Semantic Scholar
Myelin Galactolipids Are Essential for Proper Node of Ranvier Formation in the CNS
J. Dupree, T. Coetzee, A. Blight, Kinuko Suzuki +1 more
1998Journal of Neuroscience238 citations Open access
Semantic Scholar
Outcome Measures in Spinal Cord Injury
M. Alexander, Kim D. Anderson, F. Biering-Sørensen, A. Blight +28 more
2009Spinal Cord222 citations Open access
Semantic Scholar
Central axons in injured cat spinal cord recover electrophysiological function following remyelination by Schwann cells.
A. Blight, W. Young
1989Journal of Neurological Sciences199 citations
Semantic Scholar
Chondroitinase ABCI Improves Locomotion and Bladder Function following Contusion Injury of the Rat Spinal Cord
A. Caggiano, M. Zimber, Anindita Ganguly, A. Blight +1 more
2005Journal of Neurotrauma194 citations
Semantic Scholar
Effects of silica on the outcome from experimental spinal cord injury: implication of macrophages in secondary tissue damage.
A. Blight
1994Neuroscience192 citations
Semantic Scholar
Extent of spontaneous motor recovery after traumatic cervical sensorimotor complete spinal cord injury
J. Steeves, J. Kramer, J. Fawcett, J. Cragg +12 more
2011Spinal Cord185 citations Open access
Semantic Scholar
Effect of 4-aminopyridine on axonal conduction-block in chronic spinal cord injury.
A. Blight
1989Brain Research Bulletin179 citations
Semantic Scholar
Dose comparison trial of sustained-release fampridine in multiple sclerosis
A. Goodman, Theodore R. Brown, Jeffrey A. Cohen, L. Krupp +5 more
2008Neurology178 citations
Semantic Scholar
Morphometric analysis of a model of spinal cord injury in guinea pigs, with behavioral evidence of delayed secondary pathology.
A. Blight
1991Journal of Neurological Sciences171 citations
Semantic Scholar
Fampridine-SR in multiple sclerosis: a randomized, double-blind, placebo-controlled, dose-ranging study
A. Goodman, Jeffrey A. Cohen, A. Cross, T. Vollmer +4 more
2007Multiple Sclerosis155 citations
Semantic Scholar
Differential effects of low and high concentrations of 4-aminopyridine on axonal conduction in normal and injured spinal cord.
R. Shi, A. Blight
1997Neuroscience132 citations
Semantic Scholar
Computer simulation of action potentials and afterpotentials in mammalian myelinated axons: the case for a lower resistance myelin sheath.
A. Blight
1985Neuroscience132 citations
Semantic Scholar
Chondroitinase Improves Anatomical and Functional Outcomes After Primate Spinal Cord Injury
E. Rosenzweig, E. Salegio, Justine J Liang, J. Weber +18 more
2019Nature Neuroscience115 citations Open access
Semantic Scholar
Timed 25-Foot Walk
J. Hobart, A. Blight, A. Goodman, F. Lynn +1 more
2013Neurology112 citations
Semantic Scholar
Characterization of neurological recovery following traumatic sensorimotor complete thoracic spinal cord injury
J. Zariffa, J. Kramer, J. Fawcett, D. Lammertse +8 more
2011Spinal Cord106 citations
Semantic Scholar
Quinolinic acid accumulation and functional deficits following experimental spinal cord injury.
A. Blight, Timothy I. Cohen, Kuniaki Saito, M. Heyes
1995Brain : a journal of neurology106 citations
Semantic Scholar
Dalfampridine: a brief review of its mechanism of action and efficacy as a treatment to improve walking in patients with multiple sclerosis
J. Dunn, A. Blight
2011Current Medical Research and Opinion104 citations
Semantic Scholar
Miracles and molecules—progress in spinal cord repair
A. Blight
2002Nature Neuroscience104 citations
Semantic Scholar
Challenges for defining minimal clinically important difference (MCID) after spinal cord injury
Xiao-Liang Wu, Jie Liu, L. G. Tanadini, D. Lammertse +17 more
2014Spinal Cord96 citations Open access
Semantic Scholar
Functional Reconnection of Severed Mammalian Spinal Cord Axons with Polyethylene Glycol
R. Shi, R. Borgens, A. Blight
1999Journal of Neurotrauma90 citations
Semantic Scholar
A Grading System To Evaluate Objectively the Strength of Pre-Clinical Data of Acute Neuroprotective Therapies for Clinical Translation in Spinal Cord Injury
B. Kwon, E. Okon, E. Tsai, M. Beattie +11 more
2011Journal of Neurotrauma89 citations Open access
Semantic Scholar
Depolarizing afterpotentials in myelinated axons of mammalian spinal cord.
A. Blight, S. Someya
1985Neuroscience87 citations
Semantic Scholar
Quinolinic Acid is Increased in CSF and Associated with Mortality after Traumatic Brain Injury in Humans
E. Sinz, P. Kochanek, M. Heyes, S. Wisniewski +5 more
1998Journal of Cerebral Blood Flow and Metabolism83 citations
Semantic Scholar
Spinal cord compression injury in guinea pigs: structural changes of endothelium and its perivascular cell associations after blood-brain barrier breakdown and repair.
C. Jaeger, A. Blight
1997Experimental Neurology78 citations
Semantic Scholar
Conduction block in acute and chronic spinal cord injury: different dose-response characteristics for reversal by 4-aminopyridine.
R. Shi, T. M. Kelly, A. Blight
1997Experimental Neurology78 citations
Semantic Scholar
Pharmacokinetics of an Immediate‐Release Oral Formulation of Fampridine (4‐Aminopyridine) in Normal Subjects and Patients with Spinal Cord Injury
Keith C. Hayes, Mitchell A. Katz, J. Devane, J. Hsieh +3 more
2003Journal of clinical pharmacology77 citations
Semantic Scholar
Histological and functional evaluation of experimental spinal cord injury: evidence of a stepwise response to graded compression.
J. A. Gruner, Andrew Yee, A. Blight
1996Brain Research76 citations
Semantic Scholar
Augmentation by 4-aminopyridine of vestibulospinal free fall responses in chronic spinal-injured cats.
A. Blight, J. A. Gruner
1987Journal of Neurological Sciences76 citations Open access
Semantic Scholar
Quinolinic acid in the cerebrospinal fluid of children after traumatic brain injury.
M. Bell, P. Kochanek, M. Heyes, Stephen R. Wisniewski +5 more
1999Critical Care Medicine65 citations
Semantic Scholar
Morphometric analysis of blood vessels in chronic experimental spinal cord injury: hypervascularity and recovery of function.
A. Blight
1991Journal of Neurological Sciences57 citations
Semantic Scholar
Outcome Measures for Acute/Subacute Cervical Sensorimotor Complete (AIS-A) Spinal Cord Injury During a Phase 2 Clinical Trial
J. Steeves, D. Lammertse, J. Kramer, N. Kleitman +5 more
2012Topics in Spinal Cord Injury Rehabilitation56 citations Open access
Semantic Scholar
Pharmacological therapy of acute spinal cord injury: studies of high dose methylprednisolone and naloxone.
Wise Young, V. Decrescito, E. Flamm, A. Blight +1 more
1988Clinical neurosurgery56 citations
Semantic Scholar
Remyelination, revascularization, and recovery of function in experimental spinal cord injury.
A. Blight
1993Advances in neurology55 citations
Semantic Scholar
The challenge of recruitment for neurotherapeutic clinical trials in spinal cord injury
A. Blight, J. Hsieh, A. Curt, J. Fawcett +7 more
2019Spinal Cord54 citations Open access
Semantic Scholar
Long-term safety and efficacy of dalfampridine for walking impairment in patients with multiple sclerosis: Results of open-label extensions of two Phase 3 clinical trials
A. Goodman, F. Bethoux, T. Brown, R. Schapiro +4 more
2015Multiple Sclerosis52 citations Open access
Semantic Scholar
Clinical Trials in Spinal Cord Injury
A. Blight, M. Tuszynski
2006Journal of Neurotrauma48 citations
Semantic Scholar
Acute spinal cord injury: pharmacotherapy and drug development perspectives.
A. Blight, M. Zimber
2001Current opinion in investigational drugs46 citations
Semantic Scholar
Assessment of Clinically Meaningful Improvements in Self-Reported Walking Ability in Participants with Multiple Sclerosis: Results from the Randomized, Double-Blind, Phase III ENHANCE Trial of Prolonged-Release Fampridine
J. Hobart, T. Ziemssen, P. Feys, M. Linnebank +9 more
2018CNS Drugs42 citations Open access
Semantic Scholar
Pharmacokinetics of 14C-radioactivity after oral intake of a single dose of 14C-labeled fampridine (4-aminopyridine) in healthy volunteers.
A. Blight, H. Henney
2009Clinical Therapeutics41 citations
Semantic Scholar
Pharmacokinetics and safety of multiple oral doses of sustained-release 4-aminopyridine (Fampridine-SR) in subjects with chronic, incomplete spinal cord injury.
K. Hayes, P. Potter, J. Hsieh, Mitchell A. Katz +2 more
2004Archives of Physical Medicine and Rehabilitation40 citations
Semantic Scholar
Lower extremity outcome measures: considerations for clinical trials in spinal cord injury
M. Bolliger, A. Blight, E. Field-Fote, K. Musselman +20 more
2018Spinal Cord39 citations Open access
Semantic Scholar
Steady-state pharmacokinetics and tolerability of orally administered fampridine sustained-release 10-mg tablets in patients with multiple sclerosis: a 2-week, open-label, follow-up study.
T. Vollmer, A. Blight, H. Henney
2009Clinical Therapeutics38 citations
Semantic Scholar
Considerations and recommendations for selection and utilization of upper extremity clinical outcome assessments in human spinal cord injury trials
L. Jones, Anne Bryden, Tracey Wheeler, K. Tansey +21 more
2017Spinal Cord36 citations Open access
Semantic Scholar

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