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S. Kalimuddin · SciRah

Researcher profile · Semantic Scholar

S. Kalimuddin

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S. Kalimuddin — researcher profile on SciRah

h-index: 36
Works: 134
Citations: 12K

Most-cited papers

Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore.
B. Young, S. Ong, S. Kalimuddin, J. Low +23 more
2020Journal of the American Medical Association (JAMA)1,975 citations Open access
Semantic Scholar
SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls
N. Le Bert, A. Tan, Kamini Kunasegaran, Christine Y. L. Tham +15 more
2020Nature1,889 citations Open access
Semantic Scholar
Dengue and severe dengue
S. Kalimuddin, P. Chia, J. G. Low, E. Ooi
2025Clinical Microbiology Reviews1,159 citations Open access
Semantic Scholar
Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients
A. Tan, M. Linster, Chee-Wah Tan, N. Le Bert +12 more
2021Cell Reports720 citations Open access
Semantic Scholar
Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study
B. Young, Siew-Wai Fong, Y. Chan, T. Mak +25 more
2020The Lancet417 citations Open access
Semantic Scholar
Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients
C. Poh, G. Carissimo, Bei Wang, S. N. Amrun +19 more
2020Nature Communications379 citations Open access
Semantic Scholar
Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection
N. Le Bert, H. Clapham, A. Tan, Wan-Ni Chia +24 more
2020bioRxiv305 citations Open access
Semantic Scholar
A Dynamic Immune Response Shapes COVID-19 Progression
E. Z. Ong, Y. Chan, W. Leong, N. Y. Lee +7 more
2020Cell Host and Microbe293 citations Open access
Semantic Scholar
Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine breakthrough infections: a multicentre cohort study
P. Chia, S. Ong, C. Chiew, Wei-Ang Li +15 more
2021medRxiv247 citations Open access
Semantic Scholar
Rapid Progression to Acute Respiratory Distress Syndrome: Review of Current Understanding of Critical Illness from COVID-19 Infection.
Ken J. Goh, M. Choong, Elizabeth Ht Cheong, S. Kalimuddin +4 more
2020Annals of the Academy of Medicine, Singapore242 citations Open access
Semantic Scholar
Cohort study to evaluate the effect of vitamin D, magnesium, and vitamin B12 in combination on progression to severe outcomes in older patients with coronavirus (COVID-19)
Chuen W. Tan, L. Ho, S. Kalimuddin, B. Cherng +10 more
2020Nutrition (Burbank, Los Angeles County, Calif.)203 citations Open access
Semantic Scholar
Early T cell and binding antibody responses are associated with COVID-19 RNA vaccine efficacy onset
S. Kalimuddin, Christine Y. L. Tham, M. Qui, R. de Alwis +13 more
2021i Medicina182 citations Open access
Semantic Scholar
Residual SARS-CoV-2 viral antigens detected in GI and hepatic tissues from five recovered patients with COVID-19
Chun Chau Lawrence Cheung, Denise Goh, Xin-Ru Lim, T. Tien +18 more
2021Gut167 citations Open access
Semantic Scholar
A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice
R. de Alwis, E. Gan, Shi-Wei Chen, Yan Shan Leong +29 more
2020bioRxiv166 citations Open access
Semantic Scholar
Viral dynamics and immune correlates of COVID-19 disease severity
B. Young, S. Ong, L. Ng, D. Anderson +95 more
2020Clinical Infectious Diseases163 citations Open access
Semantic Scholar
Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity
S. N. Amrun, C. Lee, Bernett Lee, Siew-Wai Fong +20 more
2020EBioMedicine127 citations Open access
Semantic Scholar
Meropenem Versus Piperacillin-Tazobactam for Definitive Treatment of Bloodstream Infections Caused by AmpC β-Lactamase–Producing Enterobacter spp, Citrobacter freundii, Morganella morganii, Providencia spp, or Serratia marcescens: A Pilot Multicenter Randomized Controlled Trial (MERINO-2)
Adam G. Stewart, D. Paterson, B. Young, D. Lye +18 more
2021Open Forum Infectious Diseases75 citations Open access
Semantic Scholar
Gut Ruminococcaceae levels at baseline correlate with risk of antibiotic-associated diarrhea
Xiao-Qiong Gu, Jean X. Y. Sim, Wei L. Lee, L. Cui +14 more
2021iScience64 citations Open access
Semantic Scholar
A cohort study to evaluate the effect of combination Vitamin D, Magnesium and Vitamin B12 (DMB) on progression to severe outcome in older COVID-19 patients.
Chuen W. Tan, Liam Pock Ho, S. Kalimuddin, B. Cherng +10 more
2020medRxiv52 citations Open access
Semantic Scholar
A phase I/II randomized, double-blinded, placebo-controlled trial of a self-amplifying Covid-19 mRNA vaccine
Jenny G. H. Low, R. de Alwis, Shi-Wei Chen, S. Kalimuddin +17 more
2022npj Vaccines51 citations Open access
Semantic Scholar
Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans
S. Kalimuddin, Christine Y. L. Tham, Y. Chan, Shou-Kit Hang +17 more
2025Nature Microbiology43 citations Open access
Semantic Scholar
Asymptomatic COVID‐19: disease tolerance with efficient anti‐viral immunity against SARS‐CoV‐2
Y. Chan, Siew-Wai Fong, C. Poh, G. Carissimo +22 more
2021EMBO Molecular Medicine43 citations Open access
Semantic Scholar
Sensitive Detection of Total Anti-Spike Antibodies and Isotype Switching in Asymptomatic and Symptomatic COVID-19 Patients
Yun S. Goh, J. Chavatte, Alicia Lim Jieling, Bernett Lee +19 more
2020Social Science Research Network42 citations
Semantic Scholar
Acquisition of regulator on virulence plasmid of hypervirulent Klebsiella allows bacterial lifestyle switch in response to iron
Wilson H. W. Chu, Yi-Han Tan, Si-Yin Tan, Ya-Hua Chen +5 more
2023mBio41 citations Open access
Semantic Scholar
Pregnancy Outcomes in COVID-19: A Prospective Cohort Study in Singapore.
Citra N. Z. Mattar, S. Kalimuddin, S. Sadarangani, S. Tagore +19 more
2020Annals of the Academy of Medicine, Singapore39 citations Open access
Semantic Scholar
Adverse effects following anti–COVID-19 vaccination with mRNA-based BNT162b2 are alleviated by altering the route of administration and correlate with baseline enrichment of T and NK cell genes
A. Syenina, E. Gan, Justin Z. N. Toh, R. de Alwis +15 more
2022PLoS Biology37 citations Open access
Semantic Scholar
Viral Dynamics and Immune Correlates of Coronavirus Disease 2019 (COVID-19) Severity
E. Young, X. Ong, P. Ng, E. Anderson +22 more
202036 citations
Semantic Scholar
Insights into dengue immunity from vaccine trials
E. Ooi, S. Kalimuddin
2023Science Translational Medicine35 citations
Semantic Scholar
Potent neutralizing antibodies in the sera of convalescent COVID-19 patients are directed against conserved linear epitopes on the SARS-CoV-2 spike protein
C. Poh, G. Carissimo, Bei Wang, S. N. Amrun +15 more
2020bioRxiv33 citations Open access
Semantic Scholar
Different pattern of pre-existing SARS-COV-2 specific T cell immunity in SARS-recovered and uninfected individuals
N. Le Bert, A. Tan, Kamini Kunasegaran, Christine Y. L. Tham +15 more
2020bioRxiv33 citations Open access
Semantic Scholar
Cefiderocol versus standard therapy for hospital-acquired and health-care-associated Gram-negative bacterial bloodstream infection (the GAME CHANGER trial): an open-label, parallel-group, randomised trial.
David L. Paterson, Helmi Sulaiman, Po-Yu Liu, M. Chatfield +26 more
2025Lancet. Infectious Diseases (Print)32 citations
Semantic Scholar
Validation of self-collected buccal swab and saliva as a diagnostic tool for COVID-19
C. W. Ku, Durai Shivani, J. Kwan, S. Loy +7 more
2020medRxiv32 citations Open access
Semantic Scholar
Phase 1 Trial of a Therapeutic Anti-Yellow Fever Virus Human Antibody.
Jenny G. H. Low, J. Ng, E. Z. Ong, S. Kalimuddin +10 more
2020New England Journal of Medicine31 citations Open access
Semantic Scholar
Early Oral Antibiotic Switch in Staphylococcus aureus Bacteraemia: The Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Early Oral Switch Protocol
Dana de Kretser, Jocelyn M. Mora, Max G. Bloomfield, Anita J. Campbell +32 more
2023Clinical Infectious Diseases26 citations Open access
Semantic Scholar
Temporal dynamics of the host molecular responses underlying severe COVID-19 progression and disease resolution
E. Z. Ong, S. Kalimuddin, Wen-Chong Chia, Sarah Ooi +6 more
2021EBioMedicine26 citations Open access
Semantic Scholar
Early peripheral blood MCEMP1 and HLA-DRA expression predicts COVID-19 prognosis
Kuan-Rong Chan, Clara W. T. Koh, D. Ng, Shijie Qin +7 more
2023EBioMedicine25 citations Open access
Semantic Scholar
Signatures of mast cell activation are associated with severe COVID-19
J. Tan, D. Anderson, Abhay P. S. Rathore, Aled O +16 more
2021medRxiv25 citations Open access
Semantic Scholar
Chronic sequelae complicate convalescence from both dengue and acute viral respiratory illness
S. Kalimuddin, Y. E. Teh, En-Wee Liang, Shay Paintal +4 more
2022PLoS Neglected Tropical Diseases24 citations Open access
Semantic Scholar
Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal beta-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia A Randomized Clinical Trial
Steven Y. C. Tong, D. Lye, D. Yahav, Archana Sud +39 more
202023 citations
Semantic Scholar
Association of SARS-CoV-2 clades with clinical, inflammatory and virologic outcomes: An observational study
B. Young, W. Wei, Siew-Wai Fong, T. Mak +22 more
2021EBioMedicine22 citations Open access
Semantic Scholar
Robust Virus-Specific Adaptive Immunity in COVID-19 Patients with SARS-CoV-2 Δ382 Variant Infection
Siew-Wai Fong, N. Yeo, Y. Chan, Yun S. Goh +22 more
2021Journal of Clinical Immunology22 citations Open access
Semantic Scholar
Mast cell activation in lungs during SARS-CoV-2 infection associated with lung pathology and severe COVID-19
Janessa Y. J. Tan, D. Anderson, Abhay P. S. Rathore, Aled O’Neill +15 more
2023Journal of Clinical Investigation21 citations Open access
Semantic Scholar
Immunological and Viral Correlates of COVID-19 Disease Severity: A Prospective Cohort Study of the First 100 Patients in Singapore
B. Young, S. Ong, L. Ng, D. Anderson +25 more
202018 citations
Semantic Scholar
Clinical features and predictors of severity in COVID-19 patients with critical illness in Singapore
S. Puah, B. Young, P. Chia, V. K. Ho +20 more
2021Scientific Reports17 citations Open access
Semantic Scholar
Immune gene expression analysis indicates the potential of a self-amplifying Covid-19 mRNA vaccine
E. Z. Ong, J. Yee, J. Ooi, A. Syenina +15 more
2022npj Vaccines16 citations Open access
Semantic Scholar
A phase 1/2 randomized, double-blinded, placebo controlled ascending dose trial to assess the safety, tolerability and immunogenicity of ARCT-021 in healthy adults
J. Low, R. de Alwis, Shi-Wei Chen, S. Kalimuddin +17 more
2021medRxiv15 citations Open access
Semantic Scholar
Data-Driven Analysis of COVID-19 Reveals Persistent Immune Abnormalities in Convalescent Severe Individuals
Jackwee Lim, K. Puan, L. Wang, K. Teng +29 more
2021Frontiers in Immunology13 citations Open access
Semantic Scholar
Early induction of SARS-CoV-2 specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients
A. Tan, M. Linster, Chee-Wah Tan, N. Le Bert +12 more
2020bioRxiv13 citations Open access
Semantic Scholar
Early oral stepdown antibiotic therapy versus continuing intravenous therapy for uncomplicated Gram-negative bacteraemia (the INVEST trial): study protocol for a multicentre, randomised controlled, open-label, phase III, non-inferiority trial
I. R. Lee, Steven Y. C. Tong, Joshua S. Davis, D. Paterson +14 more
2022Trials11 citations Open access
Semantic Scholar
Differential Cytokine Responses in Hospitalized COVID-19 Patients Limit Efficacy of Remdesivir
Y. Chan, B. Young, Siew-Wai Fong, Ying Ding +9 more
2021Frontiers in Immunology11 citations Open access
Semantic Scholar

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