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Michal Hocek · SciRah

Researcher profile · Semantic Scholar

Michal Hocek

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Michal Hocek — researcher profile on SciRah

h-index: 48
Works: 418
Citations: 8,106

Most-cited papers

Pyrrolo[2,3‐d]pyrimidine (7‐deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides
Pavla Perlíková, Michal Hocek
2017Medicinal research reviews (Print)96 citations Open access
Semantic Scholar
Enzymatic Synthesis of Base-Functionalized Nucleic Acids for Sensing, Cross-linking, and Modulation of Protein-DNA Binding and Transcription.
Michal Hocek
2019Accounts of Chemical Research75 citations Open access
Semantic Scholar
Reactive modifications of DNA nucleobases for labelling, bioconjugations, and cross-linking.
Ivana Ivancová, D. Leone, Michal Hocek
2019Current Opinion in Chemical Biology47 citations
Semantic Scholar
Carborane- or Metallacarborane-Linked Nucleotides for Redox Labeling. Orthogonal Multipotential Coding of all Four DNA Bases for Electrochemical Analysis and Sequencing.
David Kodr, Cansu Pinar Yenice, A. Šimonová, D. Saftić +8 more
2021Journal of the American Chemical Society43 citations
Semantic Scholar
Tuning of Oxidation Potential of Ferrocene for Ratiometric Redox Labeling and Coding of Nucleotides and DNA
A. Šimonová, Ivan Magriñá, Veronika Sýkorová, R. Pohl +5 more
2019Chemistry38 citations Open access
Semantic Scholar
Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides.
M. Tichy, S. Smoleń, Eva Tloušt'ová, R. Pohl +7 more
2017Journal of Medicinal Chemistry37 citations Open access
Semantic Scholar
Strategies toward protecting group-free glycosylation through selective activation of the anomeric center
A. M. Downey, Michal Hocek
2017Beilstein Journal of Organic Chemistry35 citations Open access
Semantic Scholar
Solid-phase recombinase polymerase amplification using ferrocene-labelled dNTPs for electrochemical detection of single nucleotide polymorphisms.
M. Ortiz, Miriam Jauset-Rubio, David Kodr, A. Šimonová +2 more
2021Biosensors & bioelectronics31 citations Open access
Semantic Scholar
Enzymatic synthesis of hypermodified DNA polymers for sequence-specific display of four different hydrophobic groups
Marek Ondruš, Veronika Sýkorová, L. Bednárová, R. Pohl +1 more
2020Nucleic Acids Research29 citations Open access
Semantic Scholar
Squaramate‐Modified Nucleotides and DNA for Specific Cross‐Linking with Lysine‐Containing Peptides and Proteins
Ivana Ivancová, R. Pohl, M. Hubálek, Michal Hocek
2019Angewandte Chemie29 citations Open access
Semantic Scholar
Electrochemical genosensor for the direct detection of tailed PCR amplicons incorporating ferrocene labelled dATP.
Ivan Magriñá, Anna Toldrà, M. Campàs, M. Ortiz +4 more
2019Biosensors & bioelectronics28 citations Open access
Semantic Scholar
Switching transcription with bacterial RNA polymerase through photocaging, photorelease and phosphorylation reactions in the major groove of DNA
Zuzana Vaníková, M. Janoušková, Milada Kambová, L. Krásný +1 more
2019Chemical Science28 citations Open access
Semantic Scholar
Synthesis of Nucleosides through Direct Glycosylation of Nucleobases with 5-O-Monoprotected or 5-Modified Ribose: Improved Protocol, Scope, and Mechanism.
A. M. Downey, R. Pohl, J. Roithová, Michal Hocek
2017Chemistry27 citations
Semantic Scholar
Chloroacetamide-Linked Nucleotides and DNA for Cross-Linking with Peptides and Proteins.
A. Olszewska, R. Pohl, M. Brázdová, M. Fojta +1 more
2016Bioconjugate chemistry27 citations Open access
Semantic Scholar
Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses.
Nemanja Milisavljevič, E. Konkoľová, Jaroslav Kozák, J. Hodek +11 more
2021ACS Infectious Diseases25 citations
Semantic Scholar
C-H Phosphonation of Pyrrolopyrimidines: Synthesis of Substituted 7- and 9-Deazapurine-8-phosphonate Derivatives.
Nazarii Sabat, Lenka Poštová Slavětínská, B. Klepetářová, Michal Hocek
2016Journal of Organic Chemistry25 citations
Semantic Scholar
Flexible Alkyne-Linked Thymidine Phosphoramidites and Triphosphates for Chemical or Polymerase Synthesis and Fast Postsynthetic DNA Functionalization through Copper-Catalyzed Alkyne-Azide 1,3-Dipolar Cycloaddition.
Alessandro Panattoni, R. Pohl, Michal Hocek
2018Organic Letters23 citations Open access
Semantic Scholar
The selection of a hydrophobic 7-phenylbutyl-7-deazaadenine-modified DNA aptamer with high binding affinity for the Heat Shock Protein 70
C. Mulholland, Ivana Jestřábová, Arghya Sett, Marek Ondruš +5 more
2023Communications Chemistry21 citations Open access
Semantic Scholar
Enzymatic synthesis of base-modified RNA by T7 RNA polymerase. A systematic study and comparison of 5-substituted pyrimidine and 7-substituted 7-deazapurine nucleoside triphosphates as substrates.
Nemanja Milisavljevič, Pavla Perlíková, R. Pohl, Michal Hocek
2018Organic and biomolecular chemistry21 citations Open access
Semantic Scholar
Turning Off Transcription with Bacterial RNA Polymerase through CuAAC Click Reactions of DNA Containing 5-Ethynyluracil.
Michaela Slavíčková, M. Janoušková, A. Šimonová, Hana Cahová +4 more
2018Chemistry21 citations
Semantic Scholar
Brightly Fluorescent 2'-Deoxyribonucleoside Triphosphates Bearing Methylated Bodipy Fluorophore for in Cellulo Incorporation to DNA, Imaging, and Flow Cytometry.
Pedro Güixens-Gallardo, Z. Zawada, J. Matyasovsky, D. Dziuba +3 more
2018Bioconjugate chemistry21 citations Open access
Semantic Scholar
Electrochemical Detection of Single-Nucleotide Polymorphism Associated with Rifampicin Resistance in Mycobacterium tuberculosis Using Solid-Phase Primer Elongation with Ferrocene-Linked Redox-Labeled Nucleotides
M. Ortiz, Miriam Jauset-Rubio, V. Skouridou, D. Machado +6 more
2021ACS Sensors20 citations Open access
Semantic Scholar
Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides.
A. Tokarenko, B. Líšková, S. Smoleń, Natálie Táborská +16 more
2018Journal of Medicinal Chemistry20 citations Open access
Semantic Scholar
7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action
Pavla Perlíková, G. Rylová, Petr Nauš, T. Elbert +13 more
2016Molecular Cancer Therapeutics20 citations Open access
Semantic Scholar
1,3‐Diketone‐Modified Nucleotides and DNA for Cross‐Linking with Arginine‐Containing Peptides and Proteins
D. Leone, M. Hubálek, R. Pohl, Veronika Sýkorová +1 more
2021Angewandte Chemie19 citations Open access
Semantic Scholar
2‐Allyl‐ and Propargylamino‐dATPs for Site‐Specific Enzymatic Introduction of a Single Modification in the Minor Groove of DNA
J. Matyasovsky, R. Pohl, Michal Hocek
2018Chemistry19 citations Open access
Semantic Scholar
Acetophenyl-thienyl-aniline-linked nucleotide for construction of solvatochromic fluorescence light-up DNA probes sensing protein-DNA interactions.
Pedro Güixens-Gallardo, Michal Hocek
2021Chemistry18 citations
Semantic Scholar
Oxidative DNA Cleavage with Clip‐Phenanthroline Triplex‐Forming Oligonucleotide Hybrids
Alessandro Panattoni, A. El-Sagheer, T. Brown, A. Kellett +1 more
2020ChemBioChem17 citations
Semantic Scholar
Protected 5-(hydroxymethyl)uracil nucleotides bearing visible-light photocleavable groups as building blocks for polymerase synthesis of photocaged DNA.
Soňa Boháčová, Lucie Ludvíková, Lenka Poštová Slavětínská, Zuzana Vaníková +2 more
2018Organic and biomolecular chemistry16 citations Open access
Semantic Scholar
Synthesis of Dihydroxyalkynyl and Dihydroxyalkyl Nucleotides as Building Blocks or Precursors for Introduction of Diol or Aldehyde Groups to DNA for Bioconjugations.
Matouš Krömer, Kateřina Bártová, Veronika Raindlová, Michal Hocek
2018Chemistry16 citations
Semantic Scholar
Generic Platform for the Multiplexed Targeted Electrochemical Detection of Osteoporosis-Associated Single Nucleotide Polymorphisms Using Recombinase Polymerase Solid-Phase Primer Elongation and Ferrocene-Modified Nucleoside Triphosphates
M. Ortiz, Miriam Jauset-Rubio, O. Trummer, I. Foessl +10 more
2023ACS Central Science15 citations Open access
Semantic Scholar
Thiophene-linked tetramethylbodipy-labeled nucleotide for viscosity-sensitive oligonucleotide probes of hybridization and protein-DNA interactions.
Pedro Güixens-Gallardo, Jana Humpolíčková, S. P. Miclea, R. Pohl +4 more
2020Organic and biomolecular chemistry14 citations
Semantic Scholar
Voltammetric and adsorption study of 4-nitrophenyl-triazole-labeled 2′-deoxycytidine and 7-deazaadenosine nucleosides at boron-doped diamond electrode
Jana Vosáhlová, L. Koláčná, A. Daňhel, J. Fischer +4 more
2018Journal of Electroanalytical Chemistry14 citations
Semantic Scholar
Phenothiazine-linked nucleosides and nucleotides for redox labelling of DNA.
A. Šimonová, Luděk Havran, R. Pohl, M. Fojta +1 more
2017Organic and biomolecular chemistry14 citations Open access
Semantic Scholar
5-(Hydroxymethyl)uracil and -cytosine as potential epigenetic marks enhancing or inhibiting transcription with bacterial RNA polymerase.
M. Janoušková, Zuzana Vaníková, Fabrizia Nici, Soňa Boháčová +4 more
2017Chemical Communications13 citations Open access
Semantic Scholar
Real-time Imaging of Nascent DNA in Live Cells by Monitoring the Fluorescence Lifetime of DNA-Incorporated Thiazole Orange-Modified Nucleotides.
Miroslav Kuba, P. Khoroshyy, M. Lepšík, E. Kužmová +3 more
2023Angewandte Chemie12 citations Open access
Semantic Scholar
trans-Cyclooctene- and Bicyclononyne-Linked Nucleotides for Click Modification of DNA with Fluorogenic Tetrazines and Live Cell Metabolic Labeling and Imaging
Ambra Spampinato, E. Kužmová, R. Pohl, Veronika Sýkorová +3 more
2023Bioconjugate chemistry12 citations Open access
Semantic Scholar
Chloroacetamide‐Modified Nucleotide and RNA for Bioconjugations and Cross‐Linking with RNA‐Binding Proteins
Mária Brunderová, Matouš Krömer, Marta Vlková, Michal Hocek
2022Angewandte Chemie12 citations Open access
Semantic Scholar
Nucleotide‐Bearing Benzylidene‐Tetrahydroxanthylium Near‐IR Fluorophore for Sensing DNA Replication, Secondary Structures and Interactions
Miroslav Kuba, T. Kraus, R. Pohl, Michal Hocek
2020Chemistry12 citations Open access
Semantic Scholar
Protected 2'-deoxyribonucleoside triphosphate building blocks for the photocaging of epigenetic 5-(hydroxymethyl)cytosine in DNA.
Soňa Boháčová, Zuzana Vaníková, Lenka Poštová Slavětínská, Michal Hocek
2018Organic and biomolecular chemistry12 citations Open access
Semantic Scholar
Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA.
Jana Balintová, A. Šimonová, Magdalena Białek-Pietras, A. Olejniczak +2 more
2017Bioorganic & Medicinal Chemistry Letters12 citations
Semantic Scholar
Glucosylated 5-hydroxymethylpyrimidines as epigenetic DNA bases regulating transcription and restriction cleavage.
Aswathi Chakrapani, Olatz Ruiz-Larrabeiti, R. Pohl, M. Svoboda +2 more
2022Chemistry11 citations
Semantic Scholar
2-Formyl-dATP as Substrate for Polymerase Synthesis of Reactive DNA Bearing an Aldehyde Group in the Minor Groove.
Matouš Krömer, Mária Brunderová, Ivana Ivancová, Lenka Poštová Slavětínská +1 more
2020ChemPlusChem11 citations
Semantic Scholar
Synthesis of 2′-deoxycytidine and its triphosphate bearing tryptophan-based imidazolinone fluorophore for environment sensitive fluorescent labelling of DNA
Miroslav Kuba, R. Pohl, Michal Hocek
2018Tetrahedron11 citations
Semantic Scholar
Trifluoroacetophenone-Linked Nucleotides and DNA for Studying of DNA-Protein Interactions by 19F NMR Spectroscopy.
A. Olszewska, R. Pohl, Michal Hocek
2017Journal of Organic Chemistry11 citations
Semantic Scholar
Duplex Electrochemical DNA Sensor to Detect Bacillus anthracis CAP and PAG DNA Targets Based on the Incorporation of Tailed Primers and Ferrocene-Labeled dATP
Ivan Magriñá, Miriam Jauset-Rubio, M. Ortiz, H. Tomaso +3 more
2019ACS Omega10 citations Open access
Semantic Scholar
C–H Imidation of 7-Deazapurines
Nazarii Sabat, Lenka Poštová Slavětínská, B. Klepetářová, Michal Hocek
2018ACS Omega10 citations Open access
Semantic Scholar
Isomeric Naphtho‐Fused 7‐Deazapurine Nucleosides and Nucleotides: Synthesis, Biological Activity, Photophysical Properties and Enzymatic Incorporation to Nucleic Acids
K. Ghosh, Pavla Perlíková, Vojtěch Havlíček, Chao Yang +7 more
201810 citations
Semantic Scholar
Polymerase Synthesis of DNA Containing Iodinated Pyrimidine or 7‐Deazapurine Nucleobases and Their Post‐synthetic Modifications through the Suzuki‐Miyaura Cross‐Coupling Reactions
Veronika Sýkorová, M. Tichy, Michal Hocek
2021ChemBioChem9 citations
Semantic Scholar
Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides.
Lucia Veselovská, Natalie Kudlova, S. Gurská, B. Líšková +13 more
2020Chemistry9 citations
Semantic Scholar

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