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J. P. Rigalli · SciRah

Researcher profile · Semantic Scholar

J. P. Rigalli

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J. P. Rigalli — researcher profile on SciRah

h-index: 20
Works: 60
Citations: 1,171

Most-cited papers

ABC Transporters: Regulation and Association with Multidrug Resistance in Hepatocellular Carcinoma and Colorectal Carcinoma.
M. P. Ceballos, J. P. Rigalli, L. Ceré, M. Semeniuk +2 more
2019Current Medicinal Chemistry95 citations Open access
Semantic Scholar
Comparing Approaches to Normalize, Quantify, and Characterize Urinary Extracellular Vesicles
C. Blijdorp, Omar A Z Tutakhel, T. Hartjes, T. van den Bosch +18 more
2021Journal of the American Society of Nephrology81 citations Open access
Semantic Scholar
Regulation of Multidrug Resistance Proteins by Genistein in a Hepatocarcinoma Cell Line: Impact on Sorafenib Cytotoxicity
J. P. Rigalli, Nadia Ciriaci, Agostina Arias, M. P. Ceballos +6 more
2015PLoS ONE70 citations Open access
Semantic Scholar
The phytoestrogen genistein enhances multidrug resistance in breast cancer cell lines by translational regulation of ABC transporters.
J. P. Rigalli, G. N. Tocchetti, M. Arana, S. Villanueva +4 more
2016Cancer Letters65 citations Open access
Semantic Scholar
Recent Advances in Extracellular Vesicles as Drug Delivery Systems and Their Potential in Precision Medicine
B. de Jong, E. Barros, J. Hoenderop, J. P. Rigalli
2020Pharmaceutics62 citations Open access
Semantic Scholar
Pregnane X receptor mediates the induction of P-glycoprotein by spironolactone in HepG2 cells.
J. P. Rigalli, M. L. Ruiz, V. Perdomo, S. Villanueva +2 more
2011Toxicology51 citations
Semantic Scholar
Regulation of expression and activity of multidrug resistance proteins MRP2 and MDR1 by estrogenic compounds in Caco-2 cells. Role in prevention of xenobiotic-induced cytotoxicity.
Agostina Arias, J. P. Rigalli, S. Villanueva, M. L. Ruiz +5 more
2014Toxicology46 citations Open access
Semantic Scholar
Fluoride Increases Superoxide Production and Impairs the Respiratory Chain in ROS 17/2.8 Osteoblastic Cells
B. Fina, M. Lombarte, J. P. Rigalli, A. Rigalli
2014PLoS ONE46 citations Open access
Semantic Scholar
Modulation of ABC Transporters by Nuclear Receptors: Physiological, Pathological and Pharmacological Aspects.
J. P. Rigalli, G. N. Tocchetti, J. Weiss
2019Current Medicinal Chemistry31 citations
Semantic Scholar
Physiological and pathophysiological factors affecting the expression and activity of the drug transporter MRP2 in intestine. Impact on its function as membrane barrier.
M. Arana, G. N. Tocchetti, J. P. Rigalli, A. Mottino +1 more
2016Pharmacological Research31 citations Open access
Semantic Scholar
The phytoestrogens daidzein and equol inhibit the drug transporter BCRP/ABCG2 in breast cancer cells: potential chemosensitizing effect
J. P. Rigalli, Paul Scholz, G. N. Tocchetti, M. L. Ruiz +1 more
2019European Journal of Nutrition29 citations Open access
Semantic Scholar
Modulation of expression and activity of intestinal multidrug resistance-associated protein 2 by xenobiotics.
G. N. Tocchetti, J. P. Rigalli, M. Arana, S. Villanueva +1 more
2016Toxicology and Applied Pharmacology27 citations Open access
Semantic Scholar
Regulation of Biotransformation Systems and ABC Transporters by Benznidazole in HepG2 Cells: Involvement of Pregnane X-Receptor
J. P. Rigalli, V. Perdomo, M. Luquita, S. Villanueva +6 more
2012PLoS Neglected Tropical Diseases27 citations Open access
Semantic Scholar
Regulation of PXR Function by Coactivator and Corepressor Proteins: Ligand Binding Is Just the Beginning
J. P. Rigalli, Dirk Theile, Julie Nilles, J. Weiss
2021Cells25 citations Open access
Semantic Scholar
Benznidazole, the trypanocidal drug used for Chagas disease, induces hepatic NRF2 activation and attenuates the inflammatory response in a murine model of sepsis
Flavia Lambertucci, Omar Motiño, S. Villar, J. P. Rigalli +7 more
2017Toxicology and Applied Pharmacology25 citations Open access
Semantic Scholar
Modulation of Biotransformation Systems and ABC Transporters by Benznidazole in Rats
V. Perdomo, J. P. Rigalli, S. Villanueva, M. L. Ruiz +3 more
2013Antimicrobial Agents and Chemotherapy24 citations Open access
Semantic Scholar
Novel Aspects of Extracellular Vesicles in the Regulation of Renal Physiological and Pathophysiological Processes
J. P. Rigalli, E. Barros, Vera Sommers, R. Bindels +1 more
2020Frontiers in Cell and Developmental Biology23 citations Open access
Semantic Scholar
Interplay between purinergic signalling and extracellular vesicles in health and disease.
Valentina Carotti, J. P. Rigalli, Jenny van Asbeck-van der Wijst, J. Hoenderop
2022Biochemical Pharmacology22 citations
Semantic Scholar
Induction of Hepatic Multidrug Resistance-Associated Protein 3 by Ethynylestradiol Is Independent of Cholestasis and Mediated by Estrogen Receptor
M. L. Ruiz, J. P. Rigalli, Agostina Arias, S. Villanueva +4 more
2013Drug Metabolism And Disposition22 citations Open access
Semantic Scholar
Pannexin‐1 mediates fluid shear stress‐sensitive purinergic signaling and cyst growth in polycystic kidney disease
Eric H. J. Verschuren, J. P. Rigalli, C. Castenmiller, Meike Rohrbach +4 more
2020The FASEB Journal21 citations Open access
Semantic Scholar
Intestinal multidrug resistance-associated protein 2 is down-regulated in fructose-fed rats.
A. Londero, M. Arana, V. Perdomo, G. N. Tocchetti +7 more
2017Journal of Nutritional Biochemistry20 citations Open access
Semantic Scholar
Coordinated induction of GST and MRP2 by cAMP in Caco-2 cells: Role of protein kinase A signaling pathway and toxicological relevance.
M. Arana, G. N. Tocchetti, Pablo Domizi, Agostina Arias +6 more
2015Toxicology and Applied Pharmacology19 citations Open access
Semantic Scholar
Regulation of hepatic P-gp expression and activity by genistein in rats
M. Semeniuk, L. Ceré, N. Ciriaci, M. Bucci-Muñoz +5 more
2020Archives of Toxicology18 citations Open access
Semantic Scholar
Minor role of pregnane-x-receptor for acquired multidrug resistance in head and neck squamous cell carcinoma in vitro
J. P. Rigalli, Tasmin Reuter, C. Herold-Mende, G. Dyckhoff +3 more
2013Cancer Chemotherapy and Pharmacology18 citations Open access
Semantic Scholar
Proteomic profile of urinary extracellular vesicles identifies AGP1 as a potential biomarker of primary aldosteronism.
E. Barros, J. P. Rigalli, Alejandra Tapia-Castillo, A. Vecchiola +5 more
2021Endocrinology17 citations Open access
Semantic Scholar
Acute regulation of apical ABC transporters in the gut. Potential influence on drug bioavailability.
C. Domínguez, G. N. Tocchetti, J. P. Rigalli, A. Mottino
2020Pharmacological Research17 citations
Semantic Scholar
Human papilloma virus (HPV) 18 proteins E6 and E7 up-regulate ABC transporters in oropharyngeal carcinoma. Involvement of the nonsense-mediated decay (NMD) pathway.
J. P. Rigalli, Matthias Reichel, G. N. Tocchetti, Tasmin Reuter +3 more
2018Cancer Letters17 citations
Semantic Scholar
Induction of Intestinal Multidrug Resistance-Associated Protein 2 by Glucagon-Like Peptide 2 in the Rat
S. Villanueva, Agostina Arias, M. L. Ruiz, J. P. Rigalli +4 more
2010Journal of Pharmacology and Experimental Therapeutics17 citations
Semantic Scholar
Induction of intestinal multidrug resistance-associated protein 2 (Mrp2) by spironolactone in rats.
M. L. Ruiz, S. Villanueva, M. Luquita, J. Pellegrino +5 more
2009European Journal of Pharmacology17 citations
Semantic Scholar
Estrogen receptor-α mediates human multidrug resistance associated protein 3 induction by 17α-ethynylestradiol. Role of activator protein-1.
M. L. Ruiz, J. P. Rigalli, Agostina Arias, S. Villanueva +4 more
2013Biochemical Pharmacology16 citations Open access
Semantic Scholar
The antitripanocide Benznidazole promotes adaptive response to oxidative injury: Involvement of the nuclear factor-erythroid 2-related factor-2 (Nrf2) and multidrug resistance associated protein 2 (MRP2)
J. P. Rigalli, V. Perdomo, Nadia Ciriaci, D. Antonio +8 more
201615 citations
Semantic Scholar
Extracellular Vesicles as Surrogates for the Regulation of the Drug Transporters ABCC2 (MRP2) and ABCG2 (BCRP)
J. P. Rigalli, Anna Gagliardi, Klara Diester, Gzona Bajraktari-Sylejmani +10 more
2024International Journal of Molecular Sciences12 citations Open access
Semantic Scholar
The pregnane X receptor (PXR) and the nuclear receptor corepressor 2 (NCoR2) modulate cell growth in head and neck squamous cell carcinoma
J. P. Rigalli, Matthias Reichel, Tasmin Reuter, G. N. Tocchetti +4 more
2018PLoS ONE11 citations Open access
Semantic Scholar
Glucagon-like peptide 2 prevents down-regulation of intestinal multidrug resistance-associated protein 2 and P-glycoprotein in endotoxemic rats.
M. Arana, G. N. Tocchetti, Felipe Zecchinati, A. Londero +5 more
2017Toxicology11 citations Open access
Semantic Scholar
Protective effect of genistein pre-treatment on paraquat hepatotoxicity in rats.
M. Semeniuk, L. Ceré, Nadia Ciriaci, María Bucci Muñoz +7 more
2021Toxicology and Applied Pharmacology10 citations
Semantic Scholar
Acute regulation of multidrug resistance-associated protein 2 localization and activity by cAMP and estradiol-17β-d-glucuronide in rat intestine and Caco-2 cells
G. N. Tocchetti, Agostina Arias, M. Arana, J. P. Rigalli +5 more
2018Archives of Toxicology10 citations Open access
Semantic Scholar
Role of NR1I2 (pregnane X receptor) polymorphisms in head and neck squamous cell carcinoma
Tasmin Reuter, R. Warta, Dirk Theile, A. Meid +10 more
2015Naunyn-Schmiedeberg's Archives of Pharmacology10 citations
Semantic Scholar
Extracellular Vesicles and Cancer Multidrug Resistance: Undesirable Intercellular Messengers?
M. Bucci-Muñoz, A. Gola, J. P. Rigalli, M. P. Ceballos +1 more
2023Life9 citations Open access
Semantic Scholar
Antiproliferative efficacies but minor drug transporter inducing effects of paclitaxel, cisplatin, or 5-fluorouracil in a murine xenograft model for head and neck squamous cell carcinoma
Dirk Theile, Zoltán Gál, R. Warta, J. P. Rigalli +5 more
2014Cancer Biology & Therapy9 citations Open access
Semantic Scholar
Role of the RNA binding protein IGF2BP1 in cancer multidrug resistance.
A. Gola, M. Bucci-Muñoz, J. P. Rigalli, M. P. Ceballos +1 more
2024Biochemical Pharmacology8 citations Open access
Semantic Scholar
Modulation of Expression and Activity of ABC Transporters by the Phytoestrogen Genistein. Impact on Drug Disposition.
J. P. Rigalli, Nadia Ciriaci, A. Mottino, V. Catania +1 more
2016Current Medicinal Chemistry8 citations Open access
Semantic Scholar
Up-regulation of ATP-binding cassette transporters in the THP-1 human macrophage cell line by the antichagasic benznidazole
V. Perdomo, J. P. Rigalli, M. Luquita, J. Pellegrino +2 more
2016Memórias do Instituto Oswaldo Cruz8 citations Open access
Semantic Scholar
Extracellular vesicles regulate purinergic signaling and epithelial sodium channel expression in renal collecting duct cells
Eric R. Barros Lamus, Valentina Carotti, Christine R. S. Vries, Femke Witsel +6 more
2021The FASEB Journal7 citations Open access
Semantic Scholar
Inhibition of multidrug resistance‐associated protein 2 (MRP2) activity by the contraceptive nomegestrol acetate in HepG2 and Caco‐2 cells
G. N. Tocchetti, C. Domínguez, Felipe Zecchinati, M. Arana +5 more
2018European Journal of Pharmaceutical Sciences7 citations Open access
Semantic Scholar
Intraluminal nutrients acutely strengthen rat intestinal MRP2 barrier function by a glucagon‐like peptide‐2‐mediated mechanism
G. N. Tocchetti, C. Domínguez, Felipe Zecchinati, M. Arana +4 more
2020Acta Physiologica6 citations Open access
Semantic Scholar
Functional role of miR-148a in oropharyngeal cancer: influence on pregnane X receptor and P-glycoprotein expression
Tasmin Reuter, C. Herold-Mende, G. Dyckhoff, J. P. Rigalli +1 more
2019Journal of Receptor and Signal Transduction Research6 citations Open access
Semantic Scholar
Hepatic and Intestinal Multidrug Resistance-Associated Protein 2: Transcriptional and Post-transcriptional Regulation by Xenobiotics
M. Arana, G. N. Tocchetti, J. P. Rigalli, A. Mottino +2 more
20166 citations Open access
Semantic Scholar
Extracellular Vesicles as Surrogates for Drug Metabolism and Clearance: Promise vs. Reality
Anna Gagliardi, Gzona Bajraktari-Sylejmani, E. Barocelli, J. Weiss +1 more
2023Life5 citations Open access
Semantic Scholar
Effect of Glucagon-Like Peptide 2 on Hepatic, Renal, and Intestinal Disposition of 1-Chloro-2,4-dinitrobenzene
S. Villanueva, V. Perdomo, M. L. Ruiz, J. P. Rigalli +5 more
2012Drug Metabolism And Disposition5 citations Open access
Semantic Scholar
Involvement of ceramide biosynthesis in increased extracellular vesicle release in Pkd1 knock out cells
Valentina Carotti, J. van der Wijst, Eric H. J. Verschuren, Luco Rutten +5 more
2022Frontiers in Endocrinology3 citations Open access
Semantic Scholar

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