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S. Baumli · SciRah

Researcher profile · Semantic Scholar

S. Baumli

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S. Baumli — researcher profile on SciRah

h-index: 17
Works: 36
Citations: 2,367

Most-cited papers

A structural perspective of CTD function.
A. Meinhart, Tomislav Kamenski, Sabine Hoeppner, S. Baumli +1 more
2005Genes & Development405 citations Open access
Semantic Scholar
The structure of P‐TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation
S. Baumli, G. Lolli, E. Lowe, S. Troiani +5 more
2008EMBO Journal354 citations Open access
Semantic Scholar
Structure of eukaryotic RNA polymerases.
P. Cramer, K. Armache, S. Baumli, Stefan Benkert +15 more
2008Annual Review of Biophysics344 citations
Semantic Scholar
Functional architecture of RNA polymerase I.
Claus-D. Kuhn, S. Geiger, S. Baumli, M. Gartmann +6 more
2007Cell237 citations Open access
Semantic Scholar
Structure and VP16 binding of the Mediator Med25 activator interaction domain
Erika Vojnic, A. Mourão, M. Seizl, B. Simon +7 more
2011Nature Structural &Molecular Biology124 citations Open access
Semantic Scholar
Perspective of Cyclin-dependent kinase 9 (CDK9) as a Drug Target
V. Kryštof, S. Baumli, R. Fürst
2012Current pharmaceutical design120 citations Open access
Semantic Scholar
Substituted 4-(Thiazol-5-yl)-2-(phenylamino)pyrimidines Are Highly Active CDK9 Inhibitors: Synthesis, X-ray Crystal Structures, Structure–Activity Relationship, and Anticancer Activities
H. Shao, Shen-Hua Shi, Shi-Liang Huang, A. J. Hole +10 more
2013Journal of Medicinal Chemistry111 citations Open access
Semantic Scholar
Halogen bonds form the basis for selective P-TEFb inhibition by DRB.
S. Baumli, J. Endicott, L. Johnson
2010Chemistry and Biology111 citations Open access
Semantic Scholar
CDK Inhibitors Roscovitine and CR8 Trigger Mcl-1 Down-Regulation and Apoptotic Cell Death in Neuroblastoma Cells.
K. Bettayeb, Dianne Baunbæk, Claire Delehouzé, Nadège Loaëc +8 more
2010Genes & cancer87 citations Open access
Semantic Scholar
A Conserved Mediator Hinge Revealed in the Structure of the MED7·MED21 (Med7·Srb7) Heterodimer*
S. Baumli, Sabine Hoeppner, P. Cramer
2005Journal of Biological Chemistry87 citations Open access
Semantic Scholar
Identification, structure, and functional requirement of the Mediator submodule Med7N/31
Tobias Koschubs, M. Seizl, L. Larivière, F. Kurth +3 more
2009EMBO Journal67 citations Open access
Semantic Scholar
Comparative Structural and Functional Studies of 4-(Thiazol-5-yl)-2-(phenylamino)pyrimidine-5-carbonitrile CDK9 Inhibitors Suggest the Basis for Isotype Selectivity
A. J. Hole, S. Baumli, H. Shao, Shen-Hua Shi +6 more
2012Journal of Medicinal Chemistry61 citations Open access
Semantic Scholar
Structure of the mediator subunit cyclin C and its implications for CDK8 function.
Sabine Hoeppner, S. Baumli, P. Cramer
2005Journal of Molecular Biology57 citations Open access
Semantic Scholar
The CDK9 C-helix Exhibits Conformational Plasticity That May Explain the Selectivity of CAN508
S. Baumli, A. J. Hole, M. Noble, J. Endicott
2012ACS Chemical Biology52 citations Open access
Semantic Scholar
Preparation and topology of the Mediator middle module
Tobias Koschubs, K. Lorenzen, S. Baumli, Saana Sandström +2 more
2010Nucleic Acids Research49 citations Open access
Semantic Scholar
Herpes Simplex Virus 1 (HSV-1) ICP22 Protein Directly Interacts with Cyclin-Dependent Kinase (CDK)9 to Inhibit RNA Polymerase II Transcription Elongation
J. Zaborowska, S. Baumli, Clélia Laitem, Dawn O’Reilly +3 more
2014PLoS ONE48 citations Open access
Semantic Scholar
The CDK9 Tail Determines the Reaction Pathway of Positive Transcription Elongation Factor b
S. Baumli, A. J. Hole, Lan Z. Wang, M. Noble +1 more
2012Structure34 citations Open access
Semantic Scholar
The binding of flavopiridol to blood serum albumin.
Daniel P. Myatt, L. Johnson, S. Baumli, G. Siligardi
2010Chirality8 citations
Semantic Scholar
The CDK9 Tail Determines the Reaction Pathway of Positive Transcription Elongation Factor b
S. Baumli, A. J. Hole, Lan-Ju Wang, Martin E. M. Noble +2 more
20124 citations
Semantic Scholar
The Mediator Med25 activator interaction domain: Structure and cooperative binding of VP16 subdomains
Erika Vojnic, A. Mourão, M. Seizl, B. Simon +6 more
20114 citations
Semantic Scholar
Substituted 4-(Thiazol-5-Yl)-2-(Phenylamino)Pyrimidines are Highly Active Cdk9 Inhibitors: Synthesis, X-Ray Crystal Structure, Sar and Anti-Cancer Activities.
H. Shao, Shen-Hua Shi, Shi-Liang Huang, A. J. Hole +10 more
20133 citations
Semantic Scholar
Flavopiridol binding to P-TEFb (CDK9/cyclin T1)
L. Johnson, S. Baumli, G. Lolli, E. Lowe
20081 citations
Semantic Scholar
Abstract 697: Synthesis and biological evaluation of 2,4,5-substituted pyrimidines as highly selective CDK9 inhibitors for cancer treatment.
H. Shao, David W. Foley, A. Abbas, A. J. Hole +9 more
20130 citations
Semantic Scholar
Structure of CDK2 in complex with cyclin A and a 2-amino-4-heteroaryl- pyrimidine inhibitor
A. J. Hole, S. Baumli, Shu-Dong Wang, J. Endicott +1 more
20130 citations
Semantic Scholar
CDK9/cyclin T in complex with CAN508
S. Baumli, A. J. Hole, J. Endicott
20120 citations
Semantic Scholar
structure of CDK9/cyclin T F241L
S. Baumli, A. J. Hole, J. Endicott
20120 citations
Semantic Scholar
Structure of CDK9/CyclinT in complex with S-CR8
A. J. Hole, J. Endicott, S. Baumli
20110 citations
Semantic Scholar
Structure of CDK9/cyclinT1 in complex with DRB
S. Baumli, L. Johnson
20100 citations
Semantic Scholar
CDk2/cyclinA in complex with DRB
S. Baumli, L. Johnson
20100 citations
Semantic Scholar
Crystal Structure of Human CDK9/cyclinT1
S. Baumli, G. Lolli, E. Lowe, L. Johnson
20080 citations
Semantic Scholar
Structure of the Mediator submodule Med7N/31
Tobias Koschubs, M. Seizl, Laurent Larivière, F. Kurth +3 more
20080 citations
Semantic Scholar
Crystal Structure of Human CDK9/cyclinT1 in complex with Flavopiridol
S. Baumli, G. Lolli, E. Lowe, L. Johnson
20080 citations
Semantic Scholar
Crystal Structure of Human CDK9/cyclinT1 in Complex with ATP
S. Baumli, G. Lolli, E. Lowe, L. Johnson
20080 citations
Semantic Scholar
Cramer Sonja Baumli , Sabine Hoeppner and Patrick ( Med 7 · Srb 7 ) Heterodimer the Structure of the MED 7 · MED 21 A Conserved Mediator Hinge Revealed in Genes : Structure and Regulation
S. Baumli, Sabine Hoeppner, P. Cramer
20050 citations
Semantic Scholar
Structure of the mediator MED7/MED21 (Med7/Srb7) subcomplex
S. Baumli, Sabine Hoeppner, P. Cramer
20050 citations
Semantic Scholar
Structure of the mediator MED7/MED21 subcomplex
S. Baumli, Sabine Hoeppner, P. Cramer
20050 citations
Semantic Scholar

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