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S. Costinean · SciRah

Researcher profile · Semantic Scholar

S. Costinean

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S. Costinean — researcher profile on SciRah

h-index: 35
Works: 68
Citations: 11K

Most-cited papers

MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
M. Fabbri, R. Garzon, Amelia Cimmino, Zhongfa Liu +14 more
2007Proceedings of the National Academy of Sciences of the United States of America1,696 citations Open access
Semantic Scholar
Modulation of miR-155 and miR-125b Levels following Lipopolysaccharide/TNF-α Stimulation and Their Possible Roles in Regulating the Response to Endotoxin Shock1
E. Tili, J. Michaille, Amelia Cimino, S. Costinean +7 more
2007Journal of Immunology1,421 citations
Semantic Scholar
Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice.
S. Costinean, N. Zanesi, Y. Pekarsky, E. Tili +3 more
2006Proceedings of the National Academy of Sciences of the United States of America865 citations
Semantic Scholar
MiR-221&222 regulate TRAIL-resistance and enhance tumorigenicity through PTEN and TIMP3 down-regulation
M. Garofalo, G. di Leva, G. Romano, G. Nuovo +12 more
2009Cancer Cell824 citations Open access
Semantic Scholar
Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver.
Shu-Hao Hsu, Bo Wang, Janaiah Kota, Jian-Hua Yu +14 more
2012Journal of Clinical Investigation758 citations Open access
Semantic Scholar
microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer
C. Braconi, T. Kogure, N. Valeri, N. Huang +6 more
2011Oncogene653 citations Open access
Semantic Scholar
Reprogramming of miRNA networks in cancer and leukemia.
S. Volinia, Marco Galasso, S. Costinean, L. Tagliavini +47 more
2010Genome Research370 citations Open access
Semantic Scholar
Modulation of mismatch repair and genomic stability by miR-155
N. Valeri, Pierluigi Gasparini, M. Fabbri, C. Braconi +20 more
2010Proceedings of the National Academy of Sciences of the United States of America369 citations Open access
Semantic Scholar
Src homology 2 domain-containing inositol-5-phosphatase and CCAAT enhancer-binding protein beta are targeted by miR-155 in B cells of Emicro-MiR-155 transgenic mice.
S. Costinean, S. Sandhu, I. Pedersen, E. Tili +8 more
2009Blood310 citations Open access
Semantic Scholar
Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer
E. Tili, J. Michaille, D. Wernicke, H. Alder +3 more
2011Proceedings of the National Academy of Sciences of the United States of America229 citations Open access
Semantic Scholar
Targeted deletion of Wwox reveals a tumor suppressor function
R. Aqeilan, F. Trapasso, Sadiq Hussain, S. Costinean +8 more
2007Proceedings of the National Academy of Sciences of the United States of America220 citations Open access
Semantic Scholar
Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation
Pierluigi Gasparini, Francesca Lovat, M. Fassan, L. Casadei +8 more
2014Proceedings of the National Academy of Sciences of the United States of America206 citations Open access
Semantic Scholar
Karyotype-specific microRNA signature in chronic lymphocytic leukemia.
R. Visone, L. Rassenti, A. Veronese, C. Taccioli +10 more
2009Blood205 citations Open access
Semantic Scholar
miR-155 regulates IFN-γ production in natural killer cells.
R. Trotta, Li Chen, David Ciarlariello, S. Josyula +7 more
2012Blood203 citations Open access
Semantic Scholar
miR-29ab1-deficiency Identifies a Negative Feedback Loop Controlling Th1 Bias that is Dysregulated in Multiple Sclerosis
K. Smith, M. Guerau-de-Arellano, S. Costinean, Jessica L. Williams +7 more
2012Journal of Immunology192 citations Open access
Semantic Scholar
MicroRNA 29 Targets Nuclear Factor-κB–Repressing Factor and Claudin 1 to Increase Intestinal Permeability
Qi-Qi Zhou, S. Costinean, C. M. Croce, A. Brasier +4 more
2014Gastroenterology166 citations Open access
Semantic Scholar
Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression
U. Santanam, N. Zanesi, Alexey Efanov, S. Costinean +8 more
2010Proceedings of the National Academy of Sciences of the United States of America165 citations Open access
Semantic Scholar
miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the Eµ-miR-155 transgenic mouse model
S. Sandhu, S. Volinia, S. Costinean, Marco Galasso +7 more
2012Proceedings of the National Academy of Sciences of the United States of America141 citations Open access
Semantic Scholar
Regulation of acute graft-versus-host disease by microRNA-155.
Parvathi Ranganathan, Catherine E. A. Heaphy, S. Costinean, Nicole Stauffer +23 more
2010Blood139 citations Open access
Semantic Scholar
MicroRNAs, the immune system and rheumatic disease
E. Tili, J. Michaille, S. Costinean, C. Croce
2008Nature Clinical Practice Rheumatology138 citations
Semantic Scholar
Regulation of Cell Size and Contractile Function by AKT in Cardiomyocytes
M. Latronico, S. Costinean, Maria Luisa Lavitrano, C. Peschle +1 more
2004Annals of the New York Academy of Sciences134 citations
Semantic Scholar
MicroRNA Profiles Discriminate among Colon Cancer Metastasis
A. Drusco, G. Nuovo, N. Zanesi, G. di Leva +14 more
2014PLoS ONE119 citations Open access
Semantic Scholar
miR-15b/16-2 deletion promotes B-cell malignancies
Francesca Lovat, M. Fassan, Pierluigi Gasparini, L. Rizzotto +7 more
2015Proceedings of the National Academy of Sciences of the United States of America103 citations Open access
Semantic Scholar
Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice.
N. Zanesi, R. Aqeilan, A. Drusco, Mohamed Kaou +11 more
2006Cancer Research76 citations
Semantic Scholar
Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells.
R. Trotta, Li Chen, S. Costinean, S. Josyula +9 more
2013Blood71 citations Open access
Semantic Scholar
Pluripotent stem cell miRNAs and metastasis in invasive breast cancer.
S. Volinia, G. Nuovo, A. Drusco, S. Costinean +29 more
2014Journal of the National Cancer Institute69 citations Open access
Semantic Scholar
MicroRNA-29b mediates altered innate immune development in acute leukemia.
Bethany L. Mundy-Bosse, S. Scoville, Li Chen, Kathleen McConnell +15 more
2016Journal of Clinical Investigation66 citations Open access
Semantic Scholar
Disruption of miR-29 Leads to Aberrant Differentiation of Smooth Muscle Cells Selectively Associated with Distal Lung Vasculature
Leah Cushing, S. Costinean, Wei Xu, Zhi-Hua Jiang +7 more
2015PLoS Genetics59 citations Open access
Semantic Scholar
Genetic Ablation of Ptprj, a Mouse Cancer Susceptibility Gene, Results in Normal Growth and Development and Does Not Predispose to Spontaneous Tumorigenesis
F. Trapasso, A. Drusco, S. Costinean, H. Alder +7 more
2006DNA and Cell Biology58 citations
Semantic Scholar
Hepatic miR-29ab1 expression modulates chronic hepatic injury
T. Kogure, S. Costinean, Irene K. Yan, C. Braconi +2 more
2012Journal of Cellular and Molecular Medicine56 citations Open access
Semantic Scholar
Tcl1 interacts with Atm and enhances NF-κB activation in hematologic malignancies.
E. Gaudio, R. Spizzo, F. Paduano, Zheng-Hua Luo +14 more
2012Blood52 citations Open access
Semantic Scholar
Aberrant expression of DNA damage response proteins is associated with breast cancer subtype and clinical features
G. Guler, Ç. Himmetoǧlu, R. Jimenez, S. Geyer +10 more
2010Breast Cancer Research and Treatment52 citations Open access
Semantic Scholar
Loss of metallothionein predisposes mice to diethylnitrosamine-induced hepatocarcinogenesis by activating NFκB target genes
S. Majumder, Satavisha Roy, T. Kaffenberger, Bo Wang +7 more
2010Cancer Research51 citations Open access
Semantic Scholar
Fhit, Wwox and AP2γ expression levels correlate with basal phenotype in breast cancer
G. Guler, K. Huebner, Ç. Himmetoǧlu, R. E. Jimenez +5 more
2009Cancer48 citations Open access
Semantic Scholar
Stem cell-related markers in primary breast cancers and associated metastatic lesions
G. Guler, S. Balci, S. Costinean, Cigdem H. Ussakli +9 more
2012Modern Pathology42 citations Open access
Semantic Scholar
Promoter hypomethylation and expression is conserved in mouse chronic lymphocytic leukemia induced by decreased or inactivated Dnmt3a
Staci L Haney, G. Upchurch, J. Opavska, D. Klinkebiel +11 more
2016Cell Reports34 citations Open access
Semantic Scholar
Wwox Suppresses Prostate Cancer Cell Growth through Modulation of ErbB2-Mediated Androgen Receptor Signaling
H. Qin, D. Iliopoulos, Tatsuya Nakamura, S. Costinean +5 more
2007Molecular Cancer Research31 citations Open access
Semantic Scholar
Hepatic loss of miR-122 predisposes mice to hepatobiliary cyst and hepatocellular carcinoma upon diethylnitrosamine exposure.
Shu-Hao Hsu, Bo Wang, Huban Kutay, H. Bid +6 more
2013American Journal of Pathology30 citations Open access
Semantic Scholar
Common Fragile Site Tumor Suppressor Genes and Corresponding Mouse Models of Cancer
A. Drusco, Y. Pekarsky, S. Costinean, A. Antenucci +5 more
2010Journal of Biomedicine and Biotechnology26 citations Open access
Semantic Scholar
Src homology 2 domain–containing inositol-5-phosphatase and CCAAT enhancer-binding protein are targeted by miR-155 in B cells of E -MiR-155 transgenic mice
S. Costinean, S. Sandhu, I. Pedersen, E. Tili +8 more
200926 citations
Semantic Scholar
Regulated Expression of miR-155 is Required for iNKT Cell Development
Alessia Burocchi, P. Pittoni, E. Tili, Alice Rigoni +3 more
2015Frontiers in Immunology24 citations Open access
Semantic Scholar
Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes
N. Lehman, N. Spassky, Muge Sak, A. Webb +25 more
2022Nature Communications15 citations Open access
Semantic Scholar
Author Correction: Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes
N. Lehman, N. Spassky, Muge Sak, A. Webb +25 more
2023Nature Communications9 citations Open access
Semantic Scholar
Primary intrathyroidal paraganglioma: histopathology and novel molecular alterations.
S. Costinean, V. Balatti, A. Bottoni, M. Old +2 more
2012Human Pathology9 citations
Semantic Scholar
Regulating the Response to Endotoxin Shock Stimulation and Their Possible Roles in a following Lipopolysaccharide/TNF-Modulation of miR-155 and miR-125b Levels
E. Tili, J. Michaille, Amelia Cimino, S. Costinean +7 more
20079 citations
Semantic Scholar
Abstract 3: OncomiR-155 targets oncogenes HDAC4 and BCL6 in a murine B cell leukemia model: A paradigm shift in the oncogenic mechanisms of microRNAs
S. Sandhu, S. Costinean, Reid Neinast, M. Parthun +2 more
20108 citations
Semantic Scholar
Hmga1 null mice are less susceptible to chemically induced skin carcinogenesis.
R. Visone, R. Iuliano, D. Palmieri, Ilter Nurettin Server +8 more
2008European Journal of Cancer7 citations
Semantic Scholar
Tcl 1 interacts with Atm and enhances NF-kB activation in hematological malignancies
E. Gaudio, R. Spizzo, F. Paduano, Zheng-Hua Luo +14 more
20114 citations
Semantic Scholar
"MIND THE GAP" IN IMMUNOHISTOCHEMICAL TECHNIQUES USED IN PATHOLOGY OF PITUITARY ADENOMAS
M. Dumbravă, S. Costinean, C. Stancu, C. Badiu +2 more
20054 citations
Semantic Scholar
Gradual Rarefaction of Hematopoietic Precursors and Atrophy in a Depleted microRNA 29a, b and c Environment
L. Kauffman, V. Balatti, L. Cascione, P. Fadda +3 more
2015PLoS ONE3 citations Open access
Semantic Scholar

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