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Iva A. Tchasovnikarova · SciRah

Researcher profile · Semantic Scholar

Iva A. Tchasovnikarova

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Iva A. Tchasovnikarova — researcher profile on SciRah

h-index: 13
Works: 25
Citations: 1,337

Most-cited papers

Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells
Iva A. Tchasovnikarova, R. Timms, Nicholas J. Matheson, Kim Wals +5 more
2015Science294 citations Open access
Semantic Scholar
The HUSH complex cooperates with TRIM28 to repress young retrotransposons and new genes
Luisa Robbez-Masson, Christopher H C Tie, L. Conde, Hale Tunbak +6 more
2018Genome Research193 citations Open access
Semantic Scholar
Hyper-activation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2
Iva A. Tchasovnikarova, R. Timms, C. Douse, Rhys C. Roberts +4 more
2017Nature Genetics154 citations Open access
Semantic Scholar
ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH Complex
R. Timms, Iva A. Tchasovnikarova, R. Antrobus, G. Dougan +1 more
2016Cell Reports123 citations Open access
Semantic Scholar
De Novo Variants in the ATPase Module of MORC2 Cause a Neurodevelopmental Disorder with Growth Retardation and Variable Craniofacial Dysmorphism.
M. J. Guillen Sacoto, Iva A. Tchasovnikarova, E. Torti, C. Forster +43 more
2020American Journal of Human Genetics93 citations Open access
Semantic Scholar
TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control
C. Douse, Iva A. Tchasovnikarova, R. Timms, A. Protasio +8 more
2020Nature Communications92 citations Open access
Semantic Scholar
Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms
C. Douse, S. Bloor, Yangci Liu, M. Shamin +4 more
2018Nature Communications81 citations Open access
Semantic Scholar
Genetic dissection of mammalian ERAD through comparative haploid and CRISPR forward genetic screens
R. Timms, Sam A. Menzies, Iva A. Tchasovnikarova, Lea C Christensen +5 more
2016Nature Communications68 citations Open access
Semantic Scholar
Defining E3 ligase–substrate relationships through multiplex CRISPR screening
R. Timms, Elijah L. Mena, Yu-Mei Leng, Mamie Z. Li +3 more
2023Nature Cell Biology60 citations Open access
Semantic Scholar
Position‐effect variegation revisited: HUSHing up heterochromatin in human cells
R. Timms, Iva A. Tchasovnikarova, P. Lehner
2016Bioessays38 citations Open access
Semantic Scholar
Haploid Genetic Screens Identify an Essential Role for PLP2 in the Downregulation of Novel Plasma Membrane Targets by Viral E3 Ubiquitin Ligases
R. Timms, Lidia M. Duncan, Iva A. Tchasovnikarova, R. Antrobus +4 more
2013PLoS Pathogens38 citations Open access
Semantic Scholar
Periphilin self-association underpins epigenetic silencing by the HUSH complex
D. Prigozhin, C. Douse, Laura E Farleigh, A. Albecka +8 more
2019bioRxiv31 citations Open access
Semantic Scholar
Competition between two HUSH complexes orchestrates the immune response to retroelement invasion.
Joshua Miguel C. Danac, Rachael E. Matthews, Akhila Gungi, Chu-Yan Qin +4 more
2024Molecules and Cells27 citations Open access
Semantic Scholar
CRAMP1 drives linker histone expression to enable Polycomb repression.
Rachael E. Matthews, Joshua Miguel C. Danac, Emily L. Naden, Laura E. Farleigh Smith +15 more
2025Molecules and Cells13 citations Open access
Semantic Scholar
TRACE generates fluorescent human reporter cell lines to characterize epigenetic pathways
Iva A. Tchasovnikarova, Sharon K. Marr, Manashree Damle, R. Kingston
2021Molecules and Cells11 citations Open access
Semantic Scholar
Beyond the Histone Code: A Physical Map of Chromatin States.
Iva A. Tchasovnikarova, R. Kingston
2018Molecules and Cells9 citations Open access
Semantic Scholar
Differential viral accessibility (DIVA) identifies alterations in chromatin architecture through large-scale mapping of lentiviral integration sites
R. Timms, Iva A. Tchasovnikarova, P. Lehner
2018Nature Protocols9 citations Open access
Semantic Scholar
LRRC58 defines an E3 ubiquitin ligase complex sensitive to cysteine abundance
D. Ramage, L. Wieske, Charlotte Crowe, J. B. Christensen +11 more
2025bioRxiv3 citations Open access
Semantic Scholar
LRRC58 defines an E3 ubiquitin ligase complex sensitive to cysteine abundance.
D. Ramage, L. Wieske, Charlotte Crowe, J. B. Christensen +12 more
2026Molecules and Cells2 citations Open access
Semantic Scholar
Proteome-wide C-degron activity profiling connects conditional regulation of the CTLH E3 ligase complex to ribosome biogenesis
Drew W. Grant, Sheng-Jiang Tan, D. Ramage, Mamie Z. Li +6 more
2026bioRxiv1 citations
Semantic Scholar
Author Correction: Defining E3 ligase–substrate relationships through multiplex CRISPR screening
R. Timms, Elijah L. Mena, Yu-Mei Leng, Mamie Z. Li +3 more
2023Nature Cell Biology1 citations Open access
Semantic Scholar
Innate immune stress pathway activation underlies heterochromatin dysfunction pathology
Roopali Pradhan, Anna F. Townley, A. Protasio, Joshua Miguel C. Danac +8 more
2026bioRxiv0 citations Open access
Semantic Scholar
Proteome-wide C-degron activity profiling connects conditional regulation of the CTLH E3 ligase complex to ribosome biogenesis.
Drew W. Grant, Sheng-Jiang Tan, D. Ramage, Mamie Z. Li +6 more
2026Molecules and Cells0 citations Open access
Semantic Scholar
Neuropathic MORC 2 mutations perturb
C. Douse, S. Bloor, Yangci Liu, M. Shamin +4 more
20180 citations
Semantic Scholar
Neuropathic mutations in MORC2 perturb GHKL ATPase dimerization dynamics and transcriptional control by multiple structural mechanisms
C. Douse, Yangci Liu, S. Bloor, M. Shamin +4 more
20180 citations Open access
Semantic Scholar
Neuropathic mutations in MORC2 perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms
C. Douse, S. Bloor, Yangci Liu, M. Shamin +4 more
2017bioRxiv0 citations Open access
Semantic Scholar

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Yangci Liu — researcher profile on SciRah

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Mamie Z. Li — researcher profile on SciRah

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