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I. Ježíšková · SciRah

Researcher profile · Semantic Scholar

I. Ježíšková

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I. Ježíšková — researcher profile on SciRah

h-index: 10
Works: 75
Citations: 294

Most-cited papers

Monitoring of minimal residual disease in acute myeloid leukemia with frequent and rare patient‐specific NPM1 mutations
D. Dvorakova, Z. Ráčil, I. Ježíšková, I. Palásek +4 more
2010American journal of hematology/oncology40 citations Open access
Semantic Scholar
Detection and treatment of molecular relapse in acute myeloid leukemia with RUNX1 (AML1), CBFB, or MLL gene translocations: frequent quantitative monitoring of molecular markers in different compartments and correlation with WT1 gene expression.
M. Doubek, I. Palásek, Z. Pospíšil, M. Borsky +7 more
2009Experimental Hematology29 citations Open access
Semantic Scholar
Increasing hematopoietic microchimerism is a reliable indicator of incipient AML relapse
O. Horký, Jiří Mayer, L. Kablásková, F. Rázga +5 more
2011International Journal of Laboratory Hematology22 citations
Semantic Scholar
Distribution of mutations in DNMT3A gene and the suitability of mutations in R882 codon for MRD monitoring in patients with AML
I. Ježíšková, M. Musilová, M. Čulen, Veronika Foltánková +3 more
2015International journal of hematology18 citations
Semantic Scholar
Mutations in myeloid transcription factors and activated signaling genes predict chronic myeloid leukemia outcomes
M. Perusini, Daniela Žáčková, TaeHyung Kim, K. Pagnano +18 more
2024Blood Advances17 citations Open access
Semantic Scholar
Clonal hierarchy of main molecular lesions in acute myeloid leukaemia
Zdeňka Herudková, M. Čulen, A. Folta, I. Ježíšková +8 more
2019British Journal of Haematology14 citations
Semantic Scholar
Quantitative detection of IDH2 mutation for minimal residual disease monitoring in patients with acute myeloid leukemia and its comparison with mutations in NPM1 gene
I. Ježíšková, F. Rázga, Martina Tošková, D. Dvorakova +3 more
2013Leukemia and Lymphoma13 citations
Semantic Scholar
A validation study of potential prognostic DNA methylation biomarkers in patients with acute myeloid leukemia using a custom DNA methylation sequencing panel
Šárka Šestáková, E. Cerovska, C. Šálek, D. Kundrát +6 more
2022Clinical Epigenetics11 citations Open access
Semantic Scholar
Prognostic significance of mutation profile at diagnosis and mutation persistence during disease remission in adult acute myeloid leukaemia patients
A. Folta, M. Čulen, I. Ježíšková, Zdeňka Herudková +15 more
2019British Journal of Haematology10 citations
Semantic Scholar
The influence of mutational status and biological characteristics of acute myeloid leukemia on xenotransplantation outcomes in NOD SCID gamma mice
M. Čulen, Z. Kosařová, I. Ježíšková, A. Folta +8 more
2018Journal of Cancer Research and Clinical Oncology10 citations Open access
Semantic Scholar
BCR‐ABL1 kinase domain mutational analysis of CD34+ stem/progenitor cells in newly diagnosed CML patients by next‐generation sequencing
M. Musilová, F. Rázga, T. Jurček, I. Ježíšková +7 more
2014American journal of hematology/oncology10 citations Open access
Semantic Scholar
Gemtuzumab ozogamicin plus midostaurin in conjunction with standard intensive therapy for FLT3-mutated acute myeloid leukemia patients – Czech center experience
B. Weinbergerová, M. Čerňan, T. Kabut, L. Semerád +4 more
2023Haematologica9 citations Open access
Semantic Scholar
A Case of a Novel PML/RARA Short Fusion Transcript with Truncated Transcription Variant 2 of the RARA Gene
I. Ježíšková, F. Rázga, J. Gazdová, M. Doubek +4 more
2010Molecular Diagnosis & Therapy8 citations
Semantic Scholar
Role of Treatment in the Appearance and Selection of BCR-ABL1 Kinase Domain Mutations
F. Rázga, T. Jurček, Daniela Žáčková, D. Dvorakova +4 more
2012Molecular Diagnosis & Therapy7 citations
Semantic Scholar
IDH2 mutations in patients with acute myeloid leukemia: missense p.R140 mutations are linked to disease status
I. Ježíšková, F. Rázga, M. Bajerová, Z. Ráčil +2 more
2010Leukemia and Lymphoma7 citations
Semantic Scholar
Clinical efficacy and safety of first‐line nilotinib or imatinib therapy in patients with chronic myeloid leukemia—Nationwide real life data
P. Bělohlávková, Daniela Žáčková, H. Klamová, Edgar Faber +10 more
2024Cancer Medicine6 citations Open access
Semantic Scholar
A case of a novel PML/RARA short fusion transcript with truncated transcription variant 2 of the RARA gene.
I. Ježíšková, F. Rázga, J. Gazdová, M. Doubek +4 more
2010Molecular Diagnosis & Therapy6 citations
Semantic Scholar
Evaluation of spring barley genotypes with different susceptibility to Fusarium head blight using molecular markers
Z. Nesvadba, T. Vyhnánek, I. Ježíšková, L. Tvarůžek +2 more
20185 citations Open access
Semantic Scholar
CEBPA Gene Mutational Status
F. Rázga, D. Dvorakova, Tomáš Jurřček, I. Ježíšková +2 more
2012Molecular Diagnosis & Therapy5 citations
Semantic Scholar
Failure of molecular diagnostics in chronic myeloid leukemia: an aberrant form of e13a2 BCR–ABL transcript causing false-negative results by standard polymerase chain reaction
T. Jurček, F. Rázga, I. Ježíšková, D. Dvorakova +4 more
2010Leukemia and Lymphoma5 citations
Semantic Scholar
De novo accelerated phase of chronic myeloid leukemia should be recognized even in the era of tyrosine kinase inhibitors
T. Horňák, Jiří Mayer, Petra Čičátková, L. Semerád +23 more
2024American journal of hematology/oncology4 citations Open access
Semantic Scholar
Germline Jak2-R1063H mutation interferes with normal hematopoietic development and increases risk of thrombosis and leukemic transformation
Veronika Zimolova, M. Burocziova, L. Berková, Srdjan Grusanovic +16 more
2025Leukemia3 citations Open access
Semantic Scholar
Why are not all eligible chronic myeloid leukemia patients willing to attempt tyrosine kinase inhibitor discontinuation? A Czech nationwide analysis related to the TKI stopping trial HALF
Daniela Žáčková, L. Semerád, Edgar Faber, H. Klamová +25 more
2024Leukemia3 citations Open access
Semantic Scholar
MethScore as a new comprehensive DNA methylation-based value refining the prognosis in acute myeloid leukemia
Šárka Šestáková, Cyril Šálek, D. Kundrát, E. Cerovska +6 more
2024Clinical Epigenetics3 citations Open access
Semantic Scholar
Half: A Prospective Multi-Centre Phase II Clinical Trial Evaluating the Efficacy and Safety of Tyrosine Kinase Inhibitors' Discontinuation after Two-Step Dose Reduction in Patients with Chronic Myeloid Leukemia in Deep Molecular Remission
Daniela Žáčková, E. Faber, L. Stejskal, M. Karas +19 more
2021Blood3 citations Open access
Semantic Scholar
Novel complex mutation in NPM1 gene in patient with acute myeloid leukemia
I. Ježíšková, L. Semerád, D. Dvorakova, V. Janečková +4 more
2017Leukemia and Lymphoma3 citations
Semantic Scholar
Cytochrome P450 2D6 phenotype and genotype in hypertensive patients on long-term therapy with metoprolol
J. Ďuricová, I. Peřinová, N. Jurčková, I. Ježíšková +2 more
2013Bratislava Medical Journal3 citations Open access
Semantic Scholar
The use of RAPD and AFLP markers for Characterisation of Winter Barley Genotypes for Breeding to Fusarium Head Blight Resistance
Z. Nesvadba, T. Vyhnánek, I. Ježíšková, L. Tvarůžek +2 more
20083 citations
Semantic Scholar
Somatic mutations at diagnosis in patients with chronic Phase CML receiving frontline imatinib are associated with a higher rate of treatment failure: First analysis from the international CML foundation (iCMLf) genomics alliance on the harmony platform
S. Branford, A. Albeer, Ángela Villaverde Ramiro, Joe McConnell +29 more
2025Blood2 citations
Semantic Scholar
Somatic Mutations in Myeloid Transcription Factors and in Activated Signaling Pathway, but Not in Epigenetic Modifier Pathway, Predict the Risk of Treatment Failure and Progression to Advanced Phase in Chronic Myeloid Leukemia
TaeHyung Kim, Daniela Žáčková, I. Ježíšková, Anežka Kvetková +9 more
2022Blood2 citations Open access
Semantic Scholar
Donor-derived DNA variability in fingernails of acute myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation detected by direct PCR
B. Robešová, M. Drncova, A. Folta, M. Krejci +4 more
2020Bone Marrow Transplantation2 citations
Semantic Scholar
A Comparison of Two Standardized Quantitative RT-PCRs with CE IVD Kit for Digital PCR in CML Patients with Different Level of BCR-ABL1 Transcripts
A. Folta, T. Jurček, B. Kubešová, Daniela Žáčková +2 more
2019Blood2 citations Open access
Semantic Scholar
Clonal heterogeneity in patients with cytogenetically normal acute myeloid leukemia with NPM1 mutations
D. Dvorakova, Z. Ráčil, M. Borsky, B. Robešová +4 more
2013Leukemia and Lymphoma2 citations
Semantic Scholar
Treatment of molecular relapse in patients with acute myeloid leukemia using clofarabine monotherapy
Z. Ráčil, Martina Tošková, D. Dvorakova, I. Ježíšková +4 more
2012American journal of hematology/oncology2 citations Open access
Semantic Scholar
Real World Population- Based Data from Nationwide Registry Support the Existence of Accelerated Phase in Newly Diagnosed Chronic Myeloid Leukemia (CML) Patients Even in Tyrosine Kinase Inhibitors (TKIs) Era
T. Horňák, Jiří Mayer, Petra Čičátková, L. Semerád +23 more
2023Blood1 citations
Semantic Scholar
Single and multiple point NRAS mutations in acute myeloid leukemia: a study of 327 well molecularly characterized patients
A. Ďuriníková, A. Folta, F. Pardy, J. Svatoň +9 more
2022Leukemia and Lymphoma1 citations
Semantic Scholar
Current experience with ropeginterferon Alfa-2b in Ph negative myeloproliferative neoplasm at the Department of Internal Medicine – Haematology and Oncology in Brno
Natália Podstávková, B. Weinbergerová, Jiřina Procházková, Michaela Bohúnová +5 more
2022Transfuze a hematologie dnes1 citations
Semantic Scholar
Effective NPM1 plasmid standards selection for minimal/measurable residual disease monitoring in acute myeloid leukemia
A. Folta, Markéta Sasínková, A. Ďuriníková, M. Drncova +3 more
2022Molecular Biology Reports1 citations
Semantic Scholar
Palbociclib and Ponatinib Suppress Acute Myeloid Leukemia in Patient-Derived Xenograft
Daniel Buša, T. Loja, I. Ježíšková, A. Folta +2 more
2021Blood1 citations Open access
Semantic Scholar
Analysis of Mutations in the BCR-ABL1 Kinase Domain, Using Direct Sequencing
F. Rázga, T. Jurček, I. Ježíšková, Daniela Žáčková +4 more
2012Molecular Diagnosis & Therapy1 citations
Semantic Scholar
Role of treatment in the appearance and selection of BCR-ABL1 kinase domain mutations.
F. Rázga, T. Jurček, Daniela Žáčková, D. Dvorakova +4 more
2012Molecular Diagnosis & Therapy1 citations
Semantic Scholar
The adverse prognostic impact of HMGCLL1 gene variants can be abrogated by frontline second-generation tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia.
M. Perusini, K. Pagnano, C. Pavlovsky, Daniela Žáčková +15 more
2026Leukemia0 citations
Semantic Scholar
In-frame variants in TP53 gene identified in adult leukemia samples are predominantly deleterious: a study of the TP53 Network of Education and Research Initiative on CLL.
Š. Pavlová, Johana Gombíková, Silvia Petrezsélyová, L. Macůrek +25 more
2026Journal of Pathology0 citations Open access
Semantic Scholar
DNA-based MRD monitoring enhances risk stratification during TKI dose reduction in CML: Evidence from the clinical trial
Katerina Machova Polakova, H. Žižková, Romana Vajnerova, P. Suchankova +17 more
2025Blood0 citations
Semantic Scholar
Emergence of new somatic mutations in CML patients optimally responding to tyrosine kinase inhibitor therapy: Proposal of long-term genomic monitoring
Yael Morgenstern, Gopila Gupta, Flavia Patino, M. Perusini +14 more
2025Blood0 citations
Semantic Scholar
Clinical and Prognostic Significance of Additional Chromosomal Abnormalities at Diagnosis of Chronic Myeloid Leukemia
Jiří Mayer, Petra Čičátková, Lenka Kováčová, M. Jarošová +19 more
2025American journal of hematology/oncology0 citations
Semantic Scholar
Leukemic stem cell surface markers in chronic myeloid leukaemia
Dagmar Smitalova, I. Ježíšková, Jiří Mayer, Daniela Žáčková +1 more
2023Transfuze a hematologie dnes0 citations Open access
Semantic Scholar
P669: ANALYSIS OF FACTORS INFLUENCING THE DECISION TO STOP TKI TREATMENT IN CML PATIENTS IN DEEP MOLECULAR RESPONSE
L. Semerád, Daniela Žáčková, P. Bělohlávková, J. Voglová +24 more
2023HemaSphere0 citations Open access
Semantic Scholar
New Pattern of Emerging Somatic Mutations in Optimal Responders Following Tyrosine Kinase Inhibitor Therapy in Chronic Myeloid Leukemia Patients Evidenced from Mutational Kinetic Analysis Based on Pairwise Comparison
Gopila Gupta, May Chiu, Eshrak Al-Shaibani, M. Perusini +13 more
2023Blood0 citations Open access
Semantic Scholar
A validation study of potential prognostic DNA methylation biomarkers in patients with acute myeloid leukemia using a custom DNA methylation sequencing panel
Šárka Šestáková, E. Cerovska, C. Šálek, D. Kundrát +6 more
2022Clinical Epigenetics0 citations Open access
Semantic Scholar

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