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D. Klaubert · SciRah

Researcher profile · Semantic Scholar

D. Klaubert

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D. Klaubert — researcher profile on SciRah

h-index: 28
Works: 90
Citations: 5,908

Most-cited papers

HaloTag: a novel protein labeling technology for cell imaging and protein analysis.
G. Los, L. Encell, Mark G. Mcdougall, Danette Hartzell +16 more
2008ACS Chemical Biology2,236 citations Open access
Semantic Scholar
Engineered Luciferase Reporter from a Deep Sea Shrimp Utilizing a Novel Imidazopyrazinone Substrate
M. Hall, James P. Unch, B. Binkowski, M. Valley +15 more
2012ACS Chemical Biology1,457 citations Open access
Semantic Scholar
Synthesis of Fluorinated Fluoresceins
Wei-Chuan Sun, K. Gee, D. Klaubert, R. Haugland
1997257 citations
Semantic Scholar
A novel acidotropic pH indicator and its potential application in labeling acidic organelles of live cells.
Z. Diwu, Chii-Shiarng Chen, Cailan Zhang, D. Klaubert +1 more
1999Chemistry and Biology201 citations Open access
Semantic Scholar
Fluorogenic substrates based on fluorinated umbelliferones for continuous assays of phosphatases and beta-galactosidases.
K. Gee, Wei-Chuan Sun, M. Bhalgat, R. Upson +3 more
1999Analytical Biochemistry171 citations
Semantic Scholar
Antibacterial agents that inhibit two-component signal transduction systems.
J. Barrett, R. Goldschmidt, L. Lawrence, B. Foleno +18 more
1998Proceedings of the National Academy of Sciences of the United States of America129 citations Open access
Semantic Scholar
Send Orders of Reprints at Reprints@benthamscience.org Development of a Dehalogenase-based Protein Fusion Tag Capable of Rapid, Selective and Covalent Attachment to Customizable Ligands
L. Encell, Rachel Friedman Ohana, Kris Zimmerman, Paul E. Otto +23 more
119 citations
Semantic Scholar
Fluorescent molecular probes V: a sensitive caspase-3 substrate for fluorometric assays.
Jixiang Liu, M. Bhalgat, Cailan Zhang, Z. Diwu +2 more
1999Bioorganic & Medicinal Chemistry Letters101 citations
Semantic Scholar
New bioluminogenic substrates for monoamine oxidase assays.
Wenhui Zhou, M. Valley, J. Shultz, Erika M. Hawkins +6 more
2006Journal of the American Chemical Society81 citations
Semantic Scholar
Noninvasive molecular imaging of apoptosis in vivo using a modified firefly luciferase substrate, Z-DEVD-aminoluciferin
J. Hickson, S. Ackler, D. Klaubert, J. Bouska +7 more
2010Cell Death and Differentiation68 citations
Semantic Scholar
Novel heterocyclic analogues of firefly luciferin.
C. C. Woodroofe, Poncho L. Meisenheimer, D. Klaubert, Yumi Kovic +4 more
2012Biochemistry61 citations
Semantic Scholar
A bioluminescent assay for monoamine oxidase activity.
M. Valley, Wenhui Zhou, Erika M. Hawkins, J. Shultz +8 more
2006Analytical Biochemistry61 citations
Semantic Scholar
Mass spectrometry compatible surfactant for optimized in-gel protein digestion.
S. Saveliev, C. C. Woodroofe, G. Sabat, C. Adams +3 more
2013Analytical Chemistry60 citations
Semantic Scholar
Structure and synthesis of kotanin and desmethylkotanin, metabolites of Aspergillus glaucus.
G. Büchi, D. Klaubert, R. C. Shank, S. Weinreb +1 more
1971Journal of Organic Chemistry56 citations
Semantic Scholar
N-Alkylated 6'-aminoluciferins are bioluminescent substrates for Ultra-Glo and QuantiLum luciferase: new potential scaffolds for bioluminescent assays.
C. C. Woodroofe, J. Shultz, Monika G. Wood, Jean Osterman +4 more
2008Biochemistry54 citations
Semantic Scholar
A facile protocol for the convenient preparation of amino-substituted α-bromo- and α,α-dibromo arylmethylketones
Z. Diwu, C. Beachdel, D. Klaubert
199854 citations
Semantic Scholar
Chromophore-assisted light inactivation of HaloTag fusion proteins labeled with eosin in living cells.
K. Takemoto, T. Matsuda, Mark G. Mcdougall, D. Klaubert +5 more
2011ACS Chemical Biology53 citations
Semantic Scholar
Small-molecule immunostimulants. Synthesis and activity of 7,8-disubstituted guanosines and structurally related compounds.
A. Reitz, M. G. Goodman, B. Pope, D. Argentieri +6 more
1994Journal of Medicinal Chemistry50 citations
Semantic Scholar
Electrophilic aromatic substituted luciferins as bioluminescent probes for glutathione S-transferase assays.
Wenhui Zhou, J. Shultz, Nancy Murphy, Erika M. Hawkins +7 more
2006Chemical Communications48 citations
Semantic Scholar
Addition of arylmetallics to azodicarboxylates. A novel synthesis of arylhydrazines by aromatic hydrazination
J. P. Demers, D. Klaubert
198743 citations
Semantic Scholar
Bioluminescent assays for ADME evaluation: dialing in CYP selectivity with luminogenic substrates
J. Cali, Dong-Ping Ma, Monika G. Wood, Poncho L. Meisenheimer +1 more
2012Expert Opinion on Drug Metabolism & Toxicology42 citations
Semantic Scholar
Spatial separation and bidirectional trafficking of proteins using a multi-functional reporter
Soshana P. Svendsen, C. Zimprich, Mark G. Mcdougall, D. Klaubert +1 more
2008BMC Cell Biology41 citations Open access
Semantic Scholar
Selective inhibitors of protein kinase C in a model of graft-vs-host disease
J. P. Demers, W. Hageman, Sigmond G. Johnson, D. Klaubert +2 more
199439 citations
Semantic Scholar
Fluorescent molecular probes VI: The spectral properties and potential biological applications of water-soluble Dapoxyl™ sulfonic acid
Z. Diwu, Cailan Zhang, D. Klaubert, R. Haugland
200038 citations
Semantic Scholar
Proluciferin Acetals as Bioluminogenic Substrates for Cytochrome P450 Activity and Probes for CYP3A Inhibition
Poncho L. Meisenheimer, H. T. Uyeda, Dong-Ping Ma, M. Sobol +5 more
2011Drug Metabolism And Disposition36 citations
Semantic Scholar
HaloTag: a novel reporter gene for positron emission tomography.
H. Hong, H. Benink, Yin Zhang, Yu-Nan Yang +9 more
2011American journal of translational research33 citations
Semantic Scholar
Fluorescent molecular probes I. The synthesis and biological properties of an ELF® β-glucuronidase substrate that yields fluorescent precipitates at the enzymatic activity sites
Z. Diwu, Yixin Lu, R. Upson, Mingjie Zhou +2 more
199731 citations
Semantic Scholar
Fluorescent molecular probes III. 2′,7′-Bis-(3-carboxypropyl)-5-(and-6)-carboxyfluorescein (BCPCF): a new polar dual-excitation and dual-emission pH indicator with a pKa of 7.0
Jixiang Liu, Z. Diwu, D. Klaubert
199731 citations
Semantic Scholar
5-(Pentafluorobenzoylamino)fluorescein: A selective substrate for the determination of glutathione concentration and glutathione S-transferase activity.
S. Arttamangkul, M. Bhalgat, R. Haugland, Z. Diwu +2 more
1999Analytical Biochemistry27 citations
Semantic Scholar
Methods for detection of protein-protein and protein-DNA interactions using HaloTag.
M. Urh, Danette Hartzell, Jacqui Méndez, D. Klaubert +1 more
2008Methods in molecular biology23 citations
Semantic Scholar
HALOTAG INTERCHANGEABLE LABELING TECHNOLOGY FOR CELL IMAGING AND PROTEIN CAPTURE
G. Los, N. Karassina, C. Zimprich, R. Learish +9 more
200521 citations
Semantic Scholar
Thiophene systems. 11. The synthesis of novel thieno[4,3,2-de] tricyclic ring systems
R. Russell, R. Rampulla, Caroline E. van Nievelt, D. Klaubert
199020 citations
Semantic Scholar
A bioluminescent assay for the sensitive detection of proteases.
D. Leippe, D. Nguyen, Min Zhou, T. Good +8 more
2011BioTechniques16 citations Open access
Semantic Scholar
Two Step Synthesis of Substituted Indolo[1,2-a]-Quinoxalin-6-Ones
M. Beach, R. Hope, D. Klaubert, R. Russell
199513 citations
Semantic Scholar
Molecular imaging of cytochrome P450 activity in mice.
Chiara Roncoroni, N. Rizzi, Electra Brunialti, J. Cali +3 more
2012Pharmacological Research12 citations
Semantic Scholar
Abstract: New Engineered Luciferase Reporter from a Deep Sea Shrimp
M. Hall, James P. Unch, B. Binkowski, M. Valley +14 more
201211 citations
Semantic Scholar
Novel Derivatization of Protein Thiols with Fluorinated Fluoresceins
K. Gee, Wei-Chuan Sun, D. Klaubert, R. Haugland +3 more
199611 citations
Semantic Scholar
Preparation of N-1 Substituted Thieno[3,4-d]pyrimidine-2,4-diones
R. Russell, Caroline E. van Nievelt, R. Rampulla, D. Klaubert
19929 citations
Semantic Scholar
Lipophilic sulfophenylcarbocyanine dyes: Synthesis of a new class of fluorescent cell membrane probes
W. Leung, F. Mao, R. Haugland, D. Klaubert
19968 citations
Semantic Scholar
Synthesis of 5H‐tetrazolo[5,1‐c][1,4]benzodiazepines
D. Klaubert, S. Bell, T. W. Pattison
19857 citations
Semantic Scholar
Preparation and alkylation of 1,5-dihydro-3H-1,2,4-thiadiazolo[3,4-b]quinazolin-5-one 2,2-dioxides
J. P. Demers, R. Sulsky, D. Klaubert
20096 citations
Semantic Scholar
HALOTAG™ TECHNOLOGY: CELL IMAGING AND PROTEIN ANALYSIS
G. Los, R. Learish, N. Karassina, C. Zimprich +9 more
20066 citations
Semantic Scholar
Spectral properties and biological applications of ELF enzyme substrates that yield fluorescent precipitates at the enzymatic activity sites
Z. Diwu, D. Klaubert, R. Haugland
1999Biomedical optics6 citations
Semantic Scholar
Design, synthesis and bronchodilatory activity of a series of quinazoline-3-oxides.
D. Combs, M. Rampulla, R. Russell, R. Rampulla +4 more
1990Drug design and delivery6 citations
Semantic Scholar
2 One Fusion Protein : Multiple Functions HaloTag TM Interchangeable Labeling Technology for Cell Imaging , Protein Capture and Immobilization
A. Darzins, C. Zimprich, N. Karassina, R. Learish +10 more
20055 citations
Semantic Scholar
Guanosine Derivatives as Immunostimulants. Discovery of Loxoribine
Robert H. K. Chen, M. G. Goodman, D. Argentieri, S. Bell +9 more
19945 citations
Semantic Scholar
N-Alkylated 2-Trifluoromethyl-4-quinolones by Addition of Base and an Alkylating Agent to 2-Trifluoroacetylaminoacetophenones
D. Combs, M. S. Reed, D. Klaubert
19925 citations
Semantic Scholar
Chapter 16. Recent Advances in Antifungal Agents
J. Barrett, D. Klaubert
19925 citations
Semantic Scholar
SUPPLEMENTARY MATERIAL Development of a Dehalogenase-Based Protein Fusion Tag Capable of Rapid, Selective and Covalent Attachment to Customizable Ligands
L. Encell, R. Ohana, Kris Zimmerman, Paul E. Otto +22 more
20124 citations
Semantic Scholar
Fluorescent Molecular Probes. Part 1. The Synthesis and Biological Properties of an ELF® β‐Glucuronidase Substrate That Yields Fluorescent Precipitates at the Enzymatic Activity Sites.
Z. Diwu, Yixin Lu, R. Upson, Mingjie Zhou +2 more
19974 citations
Semantic Scholar

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