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A. Ali · SciRah

Researcher profile · Semantic Scholar

A. Ali

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A. Ali — researcher profile on SciRah

h-index: 22
Works: 67
Citations: 2,873

Most-cited papers

Taurine deficiency as a driver of aging
Parminder Singh, Kishore Gollapalli, S. Mangiola, D. Schranner +52 more
2023Science398 citations Open access
Semantic Scholar
Physiologic expression of SF3B1K700E causes impaired erythropoiesis, aberrant splicing, and sensitivity to pharmacologic spliceosome modulation
E. Obeng, Ryan J. Chappell, M. Seiler, M. Chen +16 more
2016Cancer Cell354 citations Open access
Semantic Scholar
Disease-associated mutation in SRSF2 misregulates splicing by altering RNA-binding affinities
Jian Zhang, Y. Lieu, A. Ali, A. Penson +5 more
2015Proceedings of the National Academy of Sciences of the United States of America235 citations Open access
Semantic Scholar
MHF1-MHF2, a Histone-Fold-Containing Protein Complex, Participates in the Fanconi Anemia Pathway via FANCM
T. R. Singh, D. Saro, A. Ali, Xiao-feng Zheng +8 more
2010Molecules and Cells220 citations Open access
Semantic Scholar
BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome.
T. R. Singh, A. Ali, Valeria Busygina, Steven J Raynard +5 more
2008Genes & Development220 citations Open access
Semantic Scholar
FAAP100 is essential for activation of the Fanconi anemia‐associated DNA damage response pathway
Chen Ling, M. Ishiai, A. Ali, A. Medhurst +13 more
2007EMBO Journal181 citations Open access
Semantic Scholar
Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M.
T. R. Singh, Sietske T. Bakker, Sheba Agarwal, M. Jansen +13 more
2009Blood152 citations Open access
Semantic Scholar
U2AF35(S34F) Promotes Transformation by Directing Aberrant ATG7 Pre-mRNA 3’ End Formation
Sung Mi Park, Jian-Hong Ou, Lynn Chamberlain, T. Simone +7 more
2016Molecules and Cells141 citations Open access
Semantic Scholar
Gene-edited stem cells enable CD33-directed immune therapy for myeloid malignancies
F. Borot, Hui Wang, Yan Ma, T. Jafarov +3 more
2019Proceedings of the National Academy of Sciences of the United States of America120 citations Open access
Semantic Scholar
Disease-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1
Jian Zhang, A. Ali, Y. Lieu, Zhao-Qi Liu +5 more
2019Molecules and Cells113 citations Open access
Semantic Scholar
FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway.
A. Ali, A. Pradhan, T. R. Singh, Chang-hu Du +6 more
2012Blood98 citations Open access
Semantic Scholar
Role of CYP1B1, MYOC, OPTN and OPTC genes in adult-onset primary open-angle glaucoma: predominance of CYP1B1 mutations in Indian patients
Arun Kumar, M. G. Basavaraj, S. Gupta, I. Qamar +6 more
2007Molecular Vision89 citations
Semantic Scholar
ATR-Dependent Phosphorylation of FANCM at Serine 1045 is Essential for FANCM Functions
T. R. Singh, A. Ali, Manikandan Paramasivam, A. Pradhan +3 more
2013Cancer Research67 citations Open access
Semantic Scholar
SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes
Y. Lieu, Zhao-Qi Liu, A. Ali, Xin Wei +7 more
2020Proceedings of the National Academy of Sciences of the United States of America65 citations Open access
Semantic Scholar
Comprehensive phenotyping of erythropoiesis in human bone marrow: Evaluation of normal and ineffective erythropoiesis
Hongxia Yan, A. Ali, L. Blanc, A. Narla +10 more
2021American journal of hematology/oncology47 citations Open access
Semantic Scholar
DEK is required for homologous recombination repair of DNA breaks
Eric A. Smith, B. Gole, Nicholas A. Willis, Rebeca Soria +13 more
2017Scientific Reports41 citations Open access
Semantic Scholar
Identification and characterization of mutations in FANCL gene: A second case of Fanconi anemia belonging to FA‐L complementation group
A. Ali, M. Kirby, M. Jansen, Francis P. Lach +6 more
2009Human Mutation37 citations Open access
Semantic Scholar
FANCM-FAAP24 and FANCJ: FA proteins that metabolize DNA
A. Ali, T. R. Singh, A. Meetei
2009Mutation research32 citations Open access
Semantic Scholar
Subversion of serotonin-receptor signaling in osteoblasts by kynurenine drives Acute Myeloid Leukemia
M. Galán-Díez, F. Borot, A. Ali, Junfei Zhao +15 more
2022Cancer Discovery29 citations Open access
Semantic Scholar
Human MutS and FANCM complexes function as redundant DNA damage sensors in the Fanconi Anemia pathway.
Min Huang, R. Kennedy, A. Ali, L. Moreau +3 more
2011DNA Repair29 citations
Semantic Scholar
Ectopic HOXB4 overcomes the inhibitory effect of tumor necrosis factor-{alpha} on Fanconi anemia hematopoietic stem and progenitor cells.
M. Milsom, B. Schiedlmeier, J. Bailey, Miok Kim +7 more
2009Blood27 citations Open access
Semantic Scholar
Severely impaired terminal erythroid differentiation as an independent prognostic marker in myelodysplastic syndromes.
A. Ali, Yumin Huang, R. Pinheiro, Fu-Min Xue +13 more
2018Blood Advances22 citations Open access
Semantic Scholar
The nuclear DEK interactome supports multi-functionality “The DEK Interactome”
Eric A. Smith, Eric F. Krumpelbeck, A. Jegga, Malte Prell +6 more
2017Proteins: Structure, Function, and Bioinformatics22 citations Open access
Semantic Scholar
Rewriting the rules for care of MDS and AML patients in the time of COVID-19
A. Raza, Amer Assal, A. Ali, J. Jurcic
2020Leukemia Research Reports19 citations Open access
Semantic Scholar
Mutation in SF3B1 gene promotes formation of polyploid giant cells in Leukemia cells
S. Mukherjee, A. Ali, V. Murty, A. Raza
2022Medical Oncology17 citations Open access
Semantic Scholar
in Genomics
Azra Raza, Nicholas Iverson, A. Ali
17 citations
Semantic Scholar
Improving Treatment for Myelodysplastic Syndromes Patients
J. Montoro, A. Yerlikaya, A. Ali, A. Raza
2018Current Treatment Options in Oncology12 citations
Semantic Scholar
Monopolar Spindle 1 (MPS1) Protein-dependent Phosphorylation of RecQ-mediated Genome Instability Protein 2 (RMI2) at Serine 112 Is Essential for BLM-Topo III α-RMI1-RMI2 (BTR) Protein Complex Function upon Spindle Assembly Checkpoint (SAC) Activation during Mitosis*
A. Pradhan, T. R. Singh, A. Ali, Kebola Wahengbam +1 more
2013Journal of Biological Chemistry12 citations Open access
Semantic Scholar
Loss of Faap20 causes hematopoietic stem and progenitor cell depletion in mice under genotoxic stress
Tingting Zhang, A. Wilson, A. Ali, S. Namekawa +3 more
2015Stem Cells11 citations Open access
Semantic Scholar
Circulating cancer giant cells with unique characteristics frequently found in patients with myelodysplastic syndromes (MDS)
A. Ali, F. Benmohamed, A. Decina, Sanjay Mukherjee +6 more
2023Medical Oncology8 citations Open access
Semantic Scholar
Characterization of the human SLC22A18 gene promoter and its regulation by the transcription factor Sp1.
A. Ali, Vineeta Bajaj, K. Gopinath, Arun Kumar
2009Gene8 citations
Semantic Scholar
Oral Rigosertib (ON 01910.Na) Treatment Produces An Encouraging Rate Of Transfusion Independence In Lower Risk Myelodysplastic Syndromes (MDS) Patients; A Genomic Methylation Profile Is Associated With Responses
A. Raza, B. Tycko, Sangmin Lee, N. Galili +8 more
20137 citations
Semantic Scholar
Survey and evaluation of mutations in the human KLF1 transcription unit
M. Gnanapragasam, J. Crispino, A. Ali, R. Weinberg +3 more
2018Scientific Reports6 citations Open access
Semantic Scholar
Two different “tales” of ATG7: Clinical relevance to myelodysplastic syndromes
A. Ali, A. Raza
2016Molecular & Cellular Oncology4 citations Open access
Semantic Scholar
Multiplex Base Editing to Protect from CD33-Directed Therapy: Implications for Immune and Gene Therapy
F. Borot, Olivier Humbert, Gregory A. Newby, Emily Fields +11 more
2023bioRxiv3 citations Open access
Semantic Scholar
A novel therapeutic bispecific format based on synthetic orthogonal heterodimers enables T cell activity against Acute myeloid leukemia
A. Burke, F. Borot, X. Du, Michael Churchill +5 more
2022Oncogene3 citations Open access
Semantic Scholar
A Targetable Bone Marrow-Niche Axis for the Treatment of Acute Myeloid Leukemia
M. Galán-Díez, F. Borot, A. Ali, Junfei Zhao +11 more
2021Blood2 citations Open access
Semantic Scholar
Pharmacological Targeting of Osteoblast-Induced MDS and AML
I. Mosialou, M. Galán-Díez, A. Vandenberg, A. Ali +2 more
2018Blood2 citations Open access
Semantic Scholar
Rigosertib in myelodysplastic syndromes (MDS)
Azra Raza, A. Ali, M. V. Ramana Reddy, Benjamin S. Hoffman +5 more
20162 citations
Semantic Scholar
Prognostic significance of neutrophil-to-lymphocyte ratio and lymphocyte-to-monocyte ratio in myelodysplastic syndromes.
M. Mushtaq, A. Ali, K. Morita, R. Pinheiro +1 more
20162 citations
Semantic Scholar
Developments in the treatment of transfusion- dependent anemia in patients with myelodysplastic syndromes: epidemiology, etiology, genetics, and targeted therapies
A. Raza, Nicholas Iverson, A. Ali
20142 citations Open access
Semantic Scholar
Methylation-based prediction of myelodysplastic syndrome survival outcomes.
Alvin Shi, A. Ali, G. Cann, R. Shaknovich +3 more
2023Journal of Clinical Oncology1 citations Open access
Semantic Scholar
Therapeutic Anti-Jagged1 Antibody Targeting Osteoblast-Related Myeloid Dysplasia to Overcome Standard of Care Resistance
I. Mosialou, A. Ali, Rachel A Adams, A. Corper +4 more
2022Blood1 citations Open access
Semantic Scholar
Prognostic significance of bone marrow cellularity in myelodysplastic syndromes: a retrospective analysis.
K. Morita, A. Ali, D. Coutinho, M. Mushtaq +1 more
20161 citations
Semantic Scholar
Current View of miRNA with Tumor Suppressor Function, Exploring MDS and AML as Models
Nicholas Iverson, N. Galili, A. Ali, A. Raza
20141 citations Open access
Semantic Scholar
Loss of TET2 Function in Myelodysplastic Syndrome Results in Intragenic Hypermethylation and Alterations in mRNA Splicing
Allegra M. Lord, Kendell Clement, R. Schneider, McConkey Marie +9 more
20141 citations
Semantic Scholar
Molecular Genetic Analysis of Myelodysplastic Syndromes (MDS) Patients with Ring Sideroblasts (RS); Independent Confirmation of Association of SF3B1 Mutations with Better Prognosis
A. Ali, Nicholas Iverson, A. Penson, A. Scott +4 more
20141 citations
Semantic Scholar
Identification and Partial Characterization of Fanconi Anemia Associated Polypeptides (FAAPs) Using a Versatile Multiprotein-Complex Purification Method.
A. Ali, T. R. Singh, Ruhikanta A. Meetei
20061 citations
Semantic Scholar
Abstract A25: A niche directed therapy for the treatment of myelodysplasia and acute myeloid leukemia
I. Mosialou, A. Ali, Rachel A Adams, A. Corper +4 more
2023Blood Cancer Discovery0 citations
Semantic Scholar
Loss of Grem1-articular cartilage progenitor cells causes osteoarthritis
Jia Q. Ng, T. Jafarov, C. Little, Tong-Tong Wang +18 more
2023bioRxiv0 citations Open access
Semantic Scholar

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