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K. Felczak · SciRah

Researcher profile · Semantic Scholar

K. Felczak

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K. Felczak — researcher profile on SciRah

h-index: 20
Works: 56
Citations: 1,132

Most-cited papers

A single-amino acid substitution in West Nile virus 2K peptide between NS4A and NS4B confers resistance to lycorine, a flavivirus inhibitor
G. Zou, F. Puig-Basagoiti, Bo Zhang, Min Qing +5 more
2008Virology138 citations Open access
Semantic Scholar
Halogenated benzimidazoles and benzotriazoles as selective inhibitors of protein kinases CK I and CK II from Saccharomyces cerevisiae and other sources.
R. Szyszka, N. Grankowski, K. Felczak, D. Shugar
1995Biochemical and Biophysical Research Communications - BBRC132 citations
Semantic Scholar
Purification and Characterization of West Nile Virus Nucleoside Triphosphatase (NTPase)/Helicase: Evidence for Dissociation of the NTPase and Helicase Activities of the Enzyme
P. Borowski, A. Niebuhr, O. Mueller, M. Bretner +3 more
2001Journal of Virology80 citations Open access
Semantic Scholar
Cross Talk between Nucleotide Synthesis Pathways with Cellular Immunity in Constraining Hepatitis E Virus Replication
Yijin Wang, Wen-Shi Wang, Lei Xu, Xin-Ying Zhou +9 more
2016Antimicrobial Agents and Chemotherapy67 citations Open access
Semantic Scholar
Multivalent glycocluster design through directed evolution
Iain S. MacPherson, J. Temme, Sevan Habeshian, K. Felczak +3 more
2011Angewandte Chemie62 citations Open access
Semantic Scholar
Triazole-linked Inhibitors of Inosine Monophosphate Dehydrogenase from Human and Mycobacterium tuberculosis
Li-Qiang Chen, Daniel J. Wilson, Yanli Xu, C. Aldrich +3 more
2010Journal of Medicinal Chemistry62 citations Open access
Semantic Scholar
Mycophenolic acid potently inhibits rotavirus infection with a high barrier to resistance development.
Yue-Bang Yin, Yijin Wang, Wen Dang, Lei Xu +14 more
2016Antiviral Research56 citations
Semantic Scholar
Relative role of halogen bonds and hydrophobic interactions in inhibition of human protein kinase CK2α by tetrabromobenzotriazole and some C5-substituted analogues.
R. Wąsik, Maja Łebska, K. Felczak, J. Poznański +1 more
2010Journal of Physical Chemistry B48 citations
Semantic Scholar
Nicotinamide adenine dinucleotide based therapeutics.
L. Chen, R. Petrelli, K. Felczak, G. Gao +4 more
2008Current Medicinal Chemistry45 citations
Semantic Scholar
NMN/NaMN adenylyltransferase (NMNAT) and NAD kinase (NADK) inhibitors: chemistry and potential therapeutic applications.
R. Petrelli, K. Felczak, L. Cappellacci
2011Current Medicinal Chemistry39 citations
Semantic Scholar
NAD-based inhibitors with anticancer potential.
K. Felczak, R. Vince, K. Pankiewicz
2014Bioorganic & Medicinal Chemistry Letters29 citations Open access
Semantic Scholar
Selective inhibition of nicotinamide adenine dinucleotide kinases by dinucleoside disulfide mimics of nicotinamide adenine dinucleotide analogues.
R. Petrelli, Y. Sham, Li-Qiang Chen, K. Felczak +11 more
2009Bioorganic & Medicinal Chemistry25 citations Open access
Semantic Scholar
High-Yield Regioselective Thiation of Biologically Important Pyrimidinones, Dihydropyrimidinones and Their Ribo, 2′-Deoxyribo and 2′, 3′-Dideoxyribo Nucleosides
K. Felczak, M. Bretner, T. Kulikowski, D. Shugar
199325 citations
Semantic Scholar
Suppression of Hepatocellular Carcinoma by Mycophenolic Acid in Experimental Models and in Patients
Kan Chen, Jiexin Sheng, B. Ma, W. Cao +12 more
2019Transplantation24 citations Open access
Semantic Scholar
Novel inhibitors of inosine monophosphate dehydrogenase in patent literature of the last decade.
R. Petrelli, Patrizia Vita, Ilaria Torquati, K. Felczak +3 more
2013Recent Patents on Anti-Cancer Drug Discovery24 citations
Semantic Scholar
Inhibition of Calcineurin or IMP Dehydrogenase Exerts Moderate to Potent Antiviral Activity against Norovirus Replication
Wen Dang, Yue-Bang Yin, Yijin Wang, Wen-Shi Wang +10 more
2017Antimicrobial Agents and Chemotherapy23 citations Open access
Semantic Scholar
Probing binding requirements of NAD kinase with modified substrate (NAD) analogues.
L. Bonnac, Li-Qiang Chen, R. Pathak, Guang-Yao Gao +8 more
2007Bioorganic & Medicinal Chemistry Letters23 citations Open access
Semantic Scholar
Nicotinamide Adenine Dinucleotide Based Therapeutics, Update.
K. Pankiewicz, R. Petrelli, Rohit Singh, K. Felczak
2015Current Medicinal Chemistry21 citations
Semantic Scholar
Modified 5′‐Trityl Nucleosides as Inhibitors of Plasmodium falciparum dUTPase
G. F. Ruda, Corinne Nguyen, P. Ziemkowski, K. Felczak +11 more
2011ChemMedChem21 citations
Semantic Scholar
Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: targeting the pyrophosphate binding sub-domain.
K. Felczak, Li-Qiang Chen, Daniel J. Wilson, Jessica M Williams +6 more
2011Bioorganic & Medicinal Chemistry20 citations Open access
Semantic Scholar
Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analogues.
Li-Qiang Chen, Guang-Yao Gao, K. Felczak, L. Bonnac +6 more
2007Journal of Medicinal Chemistry20 citations Open access
Semantic Scholar
Prodrug Activation by Cryptosporidium Thymidine Kinase*
Xin E Sun, Lisa Sharling, Mani Muthalagi, D. G. Mudeppa +6 more
2010Journal of Biological Chemistry18 citations Open access
Semantic Scholar
Mechanism of the conformational transitions in 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as revealed by NMR spectroscopy.
Guangyu Li, K. Felczak, G. Shi, Hong-Gao Yan
2006Biochemistry18 citations
Semantic Scholar
Synthesis of 4-phenoxybenzamide adenine dinucleotide as NAD analogue with inhibitory activity against enoyl-ACP reductase (InhA) of Mycobacterium tuberculosis.
L. Bonnac, Guang-Yao Gao, Li-Qiang Chen, K. Felczak +7 more
2007Bioorganic & Medicinal Chemistry Letters16 citations Open access
Semantic Scholar
Crystal structures of 5-fluoro-dUrd and its 2 and/or 4-thio analogues: models of substituted dUMP pyrimidine ring interacting with thymidylate synthase.
A. Jarmuła, R. Anulewicz, A. Leś, M. Cyranski +6 more
1998Biochimica et Biophysica Acta12 citations
Semantic Scholar
Role of Glutamate 64 in the Activation of the Prodrug 5-fluorocytosine by Yeast Cytosine Deaminase
Jifeng Wang, S. Sklenak, A. Liu, K. Felczak +3 more
2011Biochemistry11 citations Open access
Semantic Scholar
A second target of benzamide riboside
Breton N. Roussel, N. Johnson-Farley, J. Kerrigan, K. Scotto +7 more
2012Cancer Biology & Therapy10 citations Open access
Semantic Scholar
Interactions of 2'-fluoro-substituted dUMP analogues with thymidylate synthase.
P. Ziemkowski, K. Felczak, J. Poznański, T. Kulikowski +3 more
2007Biochemical and Biophysical Research Communications - BBRC9 citations
Semantic Scholar
Infrared spectra of 6-azathiouracils: an experimental matrix isolation and theoretical ab initio SCF/6-311G∗∗ study
L. Lapinski, D. Prusinowska, M. J. Nowak, M. Bretner +3 more
19969 citations
Semantic Scholar
From ribavirin to NAD analogues and back to ribavirin in search for anticancer agents
K. Pankiewicz, K. Felczak
20158 citations Open access
Semantic Scholar
1H NMR Conformational Study of a Variety of α-Anomers of C5-Substituted 2′-Deoxyuridines: Comparison to Their Antiherpetic β Counterparts
J. Poznański, K. Felczak, M. Bretner, T. Kulikowski +1 more
20017 citations
Semantic Scholar
Thiated pyrimidine deoxynucleoside analogues, potential chemotherapeutic agents, and substrates/inhibitors in various enzyme systems
M. Bretner, K. Felczak, J. Dzik, B. Gołos +7 more
19977 citations
Semantic Scholar
Thiated Analogues of 2′,3′-Dideoxy-3′-fluorothymidine and Their Phosphorylated and Phosphonylated Derivatives: Synthesis, Interaction with HIV Reverse Transcriptase, and In Vitro Anti-HIV Activity
A. Miazga, K. Felczak, M. Bretner, M. Siwecka +2 more
2003Nucleosides, Nucleotides & Nucleic Acids5 citations
Semantic Scholar
Synthesis of Methylenebis(Phosphonate) Analogues of 2-, 4-, and 6-Pyridones of Nicotinamide Adenine Dinucleotide
K. Felczak, K. Pankiewicz
2011Nucleosides, Nucleotides & Nucleic Acids3 citations
Semantic Scholar
Synthesis and antitumour properties of 2-thio-5-chloro-nucleosides
K. Felczak, M. Bretner, M. Balińska, J. Dzik +2 more
19953 citations
Semantic Scholar
Synthesis and Biological Properties of 6-Substituted 5-Fluorouridines
K. Felczak, T. Kulikowski, J. Vilpo, J. Giziewicz +1 more
19873 citations
Semantic Scholar
Novel Inhibitors of Inosine Monophosphate Dehydrogenase as Potential Anti-Cancer Drugs: A Patent Review (2002-2014)
R. Petrelli, Ilaria Torquati, K. Felczak, Daniel J. Wilson +1 more
20142 citations Open access
Semantic Scholar
X-ray Crystal and Ab Initio Structures of 3′,5′-di-O-Acetyl-N(4)-Hydroxy-2′-Deoxycytidine and Its 5-Fluoro Analogue: Models of the N(4)-OH-dCMP and N(4)-OH-FdCMP Molecules Interacting with Thymidylate Synthase
A. Jarmuła, W. Rypniewski, K. Felczak, W. Rode
20052 citations
Semantic Scholar
Selective synthesis of 4-thio derivatives of 6-alkylpyrimidine ribonucleosides with the aid of the p-nitrophenylethyl group
K. Felczak, T. Kulikowski, D. Shugar
19902 citations
Semantic Scholar
Synthesis, Conformation and Biological Properties of Selenonucleosides
K. Felczak, A. Miazga, B. Gołos, W. Rode +2 more
19991 citations
Semantic Scholar
1‐(β‐d‐Ribofuranosyl)‐6‐propylcytosine
K. B. Birnbaum, D. Shugar, K. Felczak
19981 citations
Semantic Scholar
Rehab of NAD-dependent enzymes with NAD-based inhibitors; synthesis of methylenebis(phosphonate) analogues of pyridone-3-carboxamide adenine dinucleotides
K. Felczak, K. Pankiewicz
20110 citations
Semantic Scholar
Cover Picture: Synthesis and Evaluation of Indatraline‐Based Inhibitors for Trypanothione Reductase / Design, Synthesis and Biological Evaluation of Novel Inhibitors of Trypanosoma brucei Pteridine Reductase 1 / Modified 5′‐Trityl Nucleosides as Inhibitors of Plasmodium falciparum dUTPase (ChemMedCh
J. Walton, Deuan C. Jones, P. Kiuru, A. Durie +27 more
20110 citations Open access
Semantic Scholar
1‐(β‐D‐Ribofuranosyl)‐6‐propylcytosine.
K. B. Birnbaum, D. Shugar, K. Felczak
20100 citations
Semantic Scholar
Compact NAD mimics as selective inhibitors of NAD kinases
R. Petrelli, Li-Qiang Chen, K. Felczak, M. Di Stefano +2 more
20090 citations
Semantic Scholar
Selective inhibition of nicotinamide adenine kinases (NADKs) by compact NAD mimics
R. Petrelli, K. Felczak, Li-Qiang Chen, Patrizia Vita +6 more
20090 citations
Semantic Scholar
Novel cofactor-type inhibitors of NAD-dependent enzymes. NAD-based therapeutics
Li-Qiang Chen, R. Petrelli, K. Felczak, Magdalena Olesiak +3 more
20080 citations
Semantic Scholar
DESIGN AND SYNTHESIS OF NOVEL INHIBITORS OF INOSINE MONOPHOSPHATE DEHYDROGENASE
Guang-Yao Gao, L. Bonnac, Li-Qiang Chen, K. Felczak +4 more
20070 citations
Semantic Scholar
Synthesis and anti-HIV properties of novel 6-phenylselenenyl-5-propyluracils.
A. Miazga, K. Felczak, M. Siwecka, A. Lipniacki +2 more
2007Acta Biochimica Polonica0 citations Open access
Semantic Scholar
Sequential resonance assignment of yeast cytosine deaminase in complex with a transition state analogue
L. Yao, A. Liu, Yue Li, K. Felczak +2 more
20070 citations
Semantic Scholar

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