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B. Savoldo · SciRah

Researcher profile · Semantic Scholar

B. Savoldo

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B. Savoldo — researcher profile on SciRah

h-index: 75
Works: 326
Citations: 24K

Most-cited papers

Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells
Hongwei Du, K. Hirabayashi, Sarah Ahn, N. Kren +18 more
2019Cancer Cell421 citations Open access
Semantic Scholar
Anti-CD30 CAR-T Cell Therapy in Relapsed and Refractory Hodgkin Lymphoma.
C. Ramos, N. Grover, A. Beaven, P. Lulla +20 more
2020Journal of Clinical Oncology311 citations Open access
Semantic Scholar
Immunogenicity of CAR T cells in cancer therapy
D. Wagner, Enrico Fritsche, M. Pulsipher, N. Ahmed +8 more
2021Nature Reviews Clinical Oncology276 citations Open access
Semantic Scholar
In Vivo Fate and Activity of Second- versus Third-Generation CD19-Specific CAR-T Cells in B Cell Non-Hodgkin's Lymphomas.
C. Ramos, R. Rouce, C. Robertson, A. Reyna +17 more
2018Molecular Therapy264 citations Open access
Semantic Scholar
Anti-GD2 CAR-NKT cells in patients with relapsed or refractory neuroblastoma: an interim analysis
A. Heczey, Amy N. Courtney, A. Montalbano, S. Robinson +13 more
2020Nature Medicine246 citations Open access
Semantic Scholar
Scalable Manufacturing of CAR T cells for Cancer Immunotherapy
Mohamed Abouelenein, Magdi Elsallab, S. Feldman, A. Fesnak +5 more
2021Blood Cancer Discovery238 citations Open access
Semantic Scholar
A Phase I/IIa Trial Using CD19-Targeted Third-Generation CAR T Cells for Lymphoma and Leukemia
G. Enblad, H. Karlsson, Gustav Gammelgård, J. Wenthe +11 more
2018Clinical Cancer Research234 citations Open access
Semantic Scholar
ED SUM: The efficacy of chimeric antigen receptor (CAR)-T cells in solid tumor models is enhanced by IL23 engineering.
Xingcong Ma, P. Shou, Christof C. Smith, Yu-Hui Chen +11 more
2020Nature Biotechnology228 citations Open access
Semantic Scholar
Dual Targeting CAR-T Cells with Optimal Costimulation and Metabolic Fitness enhance Antitumor Activity and Prevent Escape in Solid Tumors
K. Hirabayashi, Hongwei Du, Yang Xu, P. Shou +7 more
2021Nature Cancer202 citations Open access
Semantic Scholar
Eradication of Neuroblastoma by T Cells Redirected with an Optimized GD2-Specific Chimeric Antigen Receptor and Interleukin-15
Yu-Hui Chen, Chuang Sun, Elisa Landoni, L. Metelitsa +2 more
2019Clinical Cancer Research185 citations Open access
Semantic Scholar
Constitutive and TNFα-inducible expression of chondroitin sulfate proteoglycan 4 in glioblastoma and neurospheres: Implications for CAR-T cell therapy
S. Pellegatta, B. Savoldo, Natalia Di Ianni, C. Corbetta +8 more
2018Science Translational Medicine170 citations Open access
Semantic Scholar
B7-H3-redirected chimeric antigen receptor T cells target glioblastoma and neurospheres
Dean Nehama, Natalia Di Ianni, S. Musio, Hongwei Du +13 more
2019EBioMedicine166 citations Open access
Semantic Scholar
NKT cells co-expressing a GD2-specific chimeric antigen receptor and IL-15 show enhanced in vivo persistence and antitumor activity against neuroblastoma.
Xin Xu, Wei Huang, A. Heczey, Daofeng Liu +13 more
2019Clinical Cancer Research157 citations Open access
Semantic Scholar
THEMIS-SHP1 Recruitment by 4–1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells
Chuang Sun, P. Shou, Hongwei Du, K. Hirabayashi +10 more
2020Cancer Cell135 citations Open access
Semantic Scholar
Enhancing Chimeric Antigen Receptor T Cell Efficacy in Solid Tumors
G. Fucà, L. Reppel, Elisa Landoni, B. Savoldo +1 more
2020Clinical Cancer Research119 citations Open access
Semantic Scholar
GD2-specific CAR T cells encapsulated in an injectable hydrogel control retinoblastoma and preserve vision
Kai Wang, Yu-Hui Chen, Sarah Ahn, Min Zheng +4 more
2020Nature Cancer103 citations Open access
Semantic Scholar
Targeting brain lesions of non-small cell lung cancer by enhancing CCL2-mediated CAR-T cell migration
Hong-Xia Li, E. B. Harrison, Hui-Zhong Li, K. Hirabayashi +9 more
2022Nature Communications95 citations Open access
Semantic Scholar
Safety and efficacy of targeting CD138 with a chimeric antigen receptor for the treatment of multiple myeloma
Chuang Sun, Aruna Mahendravada, B. Ballard, Brandon Kale +8 more
2019OncoTarget90 citations Open access
Semantic Scholar
Utility of Safety Switch to Abrogate CD19.CAR T Cell-Associated Neurotoxicity.
M. Foster, B. Savoldo, Winnie Lau, Clio Rubinos +13 more
2021Blood75 citations Open access
Semantic Scholar
Fibrin gel enhances the antitumor effects of chimeric antigen receptor T cells in glioblastoma
Edikan A. Ogunnaike, A. Valdivia, M. Yazdimamaghani, Ernesto Leon +9 more
2021Science Advances75 citations Open access
Semantic Scholar
Targeting disialoganglioside GD2 with chimeric antigen receptor-redirected T cells in lung cancer
L. Reppel, Ourania Tsahouridis, J. Akulian, Ian J. Davis +6 more
2022Journal for ImmunoTherapy of Cancer73 citations Open access
Semantic Scholar
Bispecific binder redirected lentiviral vector enables in vivo engineering of CAR-T cells
J. Huckaby, Elisa Landoni, T. Jacobs, B. Savoldo +2 more
2021Journal for ImmunoTherapy of Cancer72 citations Open access
Semantic Scholar
Preclinical Evaluation of B7-H3-Specific Chimeric Antigen Receptor T cells for the Treatment of Acute Myeloid Leukemia
Eben I. Lichtman, Hongwei Du, P. Shou, Fei-Fei Song +7 more
2021Clinical Cancer Research66 citations Open access
Semantic Scholar
CD30-Redirected Chimeric Antigen Receptor T Cells Target CD30+ and CD30– Embryonal Carcinoma via Antigen-dependent and Fas/FasL Interactions
L. Hong, Yu-Hui Chen, Christof C. Smith, S. Montgomery +3 more
2018Cancer immunology research66 citations Open access
Semantic Scholar
IL-12 reprograms CAR-expressing natural killer T cells to long-lived Th1-polarized cells with potent antitumor activity
Elisa Landoni, M. Woodcock, Gabriel A. Barragán, G. Casirati +11 more
2024Nature Communications65 citations Open access
Semantic Scholar
Modifications to the Framework Regions Eliminate Chimeric Antigen Receptor Tonic Signaling
Elisa Landoni, G. Fucà, Jian Wang, V. R. Chirasani +15 more
2021Cancer immunology research64 citations Open access
Semantic Scholar
CAR-redirected natural killer T cells demonstrate superior antitumor activity to CAR-T cells through multimodal CD1d-dependent mechanisms
Xin Zhou, Ying Wang, Zhangqi Dou, G. Delfanti +14 more
2024Nature Cancer59 citations
Semantic Scholar
Machine-learning prediction of tumor antigen immunogenicity in the selection of therapeutic epitopes
Christof C. Smith, Shengjie Chai, Amber R Washington, Samuel J. Lee +9 more
2019Cancer immunology research54 citations Open access
Semantic Scholar
ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells
Elisa Bergaggio, Wei-Tien Tai, A. Aroldi, Carmen Mecca +17 more
2023Cancer Cell53 citations Open access
Semantic Scholar
CD30‐CHIMERIC ANTIGEN RECEPTOR (CAR) T CELLS FOR THERAPY OF HODGKIN LYMPHOMA (HL)
C. Ramos, Vicky Torrano, Mrinalini Bilgi, Claudia Gerken +10 more
2018Hematological Oncology50 citations Open access
Semantic Scholar
Challenges of driving CD30-directed CAR-T cells to the clinic
N. Grover, B. Savoldo
2019BMC Cancer49 citations Open access
Semantic Scholar
T Cell Receptor Stimulation Enhances the Expansion and Function of CD19 Chimeric Antigen Receptor-Expressing T Cells
N. Lapteva, Margaret Gilbert, I. Diaconu, L. Rollins +23 more
2019Clinical Cancer Research48 citations Open access
Semantic Scholar
Pretherapy metabolic tumor volume is associated with response to CD30 CAR T cells in Hodgkin lymphoma
T. Voorhees, Beibo Zhao, J. Oldan, G. Hucks +13 more
2021Blood Advances47 citations Open access
Semantic Scholar
Co-transducing B7H3 CAR-NK cells with the DNR preserves their cytolytic function against GBM in the presence of exogenous TGF-β
Kajal Chaudhry, A. Geiger, Ehsan Dowlati, H. Lang +9 more
2022Molecular Therapy: Methods & Clinical Development40 citations Open access
Semantic Scholar
In vitro elimination of epidermal growth factor receptor-overexpressing cancer cells by CD32A-chimeric receptor T cells in combination with cetuximab or panitumumab
S. Caratelli, R. Arriga, T. Sconocchia, Alessio Ottaviani +12 more
2019International Journal of Cancer40 citations Open access
Semantic Scholar
Adoptive T cell therapy: Boosting the immune system to fight cancer
Ernesto Leon, R. Ranganathan, B. Savoldo
2020Seminars in Immunology37 citations Open access
Semantic Scholar
CD30-Directed CAR-T Cells Co-Expressing CCR4 in Relapsed/Refractory Hodgkin Lymphoma and CD30+ Cutaneous T Cell Lymphoma
N. Grover, A. Ivanova, D. Moore, C. Cheng +11 more
2021Blood34 citations Open access
Semantic Scholar
Building safety into CAR-T therapy
Daniel T. Peters, B. Savoldo, N. Grover
2023Human Vaccines & Immunotherapeutics29 citations Open access
Semantic Scholar
Anti-CD30 CART cells as consolidation after autologous haematopoietic stem-cell transplantation in patients with high-risk CD30+ lymphoma: a phase 1 study
N. Grover, G. Hucks, M. Riches, Anastasia Ivanova +18 more
2024The Lancet Haematology27 citations Open access
Semantic Scholar
Long-term remission in multiply relapsed enteropathy-associated T-cell lymphoma following CD30 CAR T-cell therapy.
T. Voorhees, N. Ghosh, N. Grover, Jared G Block +7 more
2020Blood Advances26 citations Open access
Semantic Scholar
Treating hematological malignancies with cell therapy: where are we now?
Elisa Landoni, B. Savoldo
2018Expert Opinion on Biological Therapy26 citations
Semantic Scholar
The landscape of CAR-engineered innate immune cells for cancer immunotherapy
Ourania Tsahouridis, Max Xu, Feifei Song, B. Savoldo +1 more
2025Nature Cancer22 citations
Semantic Scholar
B7-H3 and CSPG4 co-targeting as Pan-CAR-T cell treatment of triple-negative breast cancer
Simone Stucchi, Roberto Borea, Susana Garcia-Recio, Manuela Zingarelli +9 more
2025Journal for ImmunoTherapy of Cancer21 citations Open access
Semantic Scholar
Cancer immunotherapy with T cells carrying bispecific receptors that mimic antibodies
Sarah Ahn, Jingjing Li, Chuang Sun, Keliang Gao +5 more
2019Cancer immunology research20 citations Open access
Semantic Scholar
4-1BB-encoding CAR causes cell death via sequestration of the ubiquitin-modifying enzyme A20
Zhangqi Dou, T. Bonacci, P. Shou, Elisa Landoni +10 more
2024Cellular & Molecular Immunology19 citations Open access
Semantic Scholar
CAR T cells for hematological malignancies
B. Savoldo, Natalie S. Grover, G. Dotti
2024Journal of Clinical Investigation19 citations Open access
Semantic Scholar
CAR T cells Targeting Human Immunoglobulin Light Chains Eradicate Mature B Cell Malignancies While Sparing a Subset of Normal B Cells
R. Ranganathan, P. Shou, Sarah Ahn, Chuang Sun +3 more
2021Clinical Cancer Research19 citations Open access
Semantic Scholar
ADOPTIVE CELL THERAPY IN TREATING PEDIATRIC SOLID TUMORS
Mekdem Tesfaye, B. Savoldo
2018Current Oncology Reports18 citations Open access
Semantic Scholar
Atlas-guided discovery of transcription factors for T cell programming
H. K. Chung, Cong Liu, Anamika Battu, Alexander N. Jambor +46 more
2023bioRxiv17 citations Open access
Semantic Scholar
A multi-kinase inhibitor screen identifies inhibitors preserving stem-cell-like chimeric antigen receptor T cells
Feifei Song, Ourania Tsahouridis, Simone Stucchi, T. Walhart +15 more
2025Nature Immunology13 citations Open access
Semantic Scholar

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