D. Duboule

Most-cited papers

1. Topology of mammalian developmental enhancers and their regulatory landscapes

   W. de Laat, D. Duboule

   2013Nature528 citations Open access

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2. A regulatory archipelago controls Hox genes transcription in digits.

   Thomas Montavon, N. Soshnikova, Bénédicte Mascrez, E. Joye +5 more

   2011Cell510 citations Open access

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3. Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids

   L. Beccari, Naomi Moris, M. Girgin, D. A. Turner +5 more

   2018Nature459 citations Open access

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4. The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system

   F. Vonk, N. Casewell, C. Henkel, A. Heimberg +32 more

   2013Proceedings of the National Academy of Sciences of the United States of America445 citations Open access

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5. A Switch Between Topological Domains Underlies HoxD Genes Collinearity in Mouse Limbs

   G. Andrey, Thomas Montavon, Bénédicte Mascrez, Federico Gonzalez +5 more

   2013Science429 citations Open access

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6. The Dynamic Architecture of Hox Gene Clusters

   D. Noordermeer, M. Leleu, E. Splinter, J. Rougemont +2 more

   2011Science408 citations Open access

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7. Considerations when investigating lncRNA function in vivo

   Andrew R. Bassett, A. Akhtar, D. Barlow, A. Bird +9 more

   2014eLife334 citations Open access

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8. Structural and Functional Differences in the Long Non-Coding RNA Hotair in Mouse and Human

   Patrick Schorderet, D. Duboule

   2011PLoS Genetics239 citations Open access

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9. Embryonic timing, axial stem cells, chromatin dynamics, and the Hox clock

   J. Deschamps, D. Duboule

   2017Genes & Development200 citations Open access

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10. Clustering of mammalian Hox genes with other H3K27me3 targets within an active nuclear domain

    Maxence Vieux-Rochas, P. Fabre, M. Leleu, D. Duboule +1 more

    2015Proceedings of the National Academy of Sciences of the United States of America165 citations Open access

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11. The HoxD cluster is a dynamic and resilient TAD boundary controlling the segregation of antagonistic regulatory landscapes

    Eddie Rodríguez-Carballo, Lucille Lopez-Delisle, Ye Zhan, P. Fabre +6 more

    2017bioRxiv160 citations Open access

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12. Conservation and Divergence of Regulatory Strategies at Hox Loci and the Origin of Tetrapod Digits

    J. Woltering, D. Noordermeer, M. Leleu, D. Duboule

    2014PLoS Biology151 citations Open access

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13. Temporal dynamics and developmental memory of 3D chromatin architecture at Hox gene loci

    D. Noordermeer, M. Leleu, Patrick Schorderet, E. Joye +2 more

    2014eLife138 citations Open access

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14. Convergent evolution of complex regulatory landscapes and pleiotropy at Hox loci

    Nicolas Lonfat, Thomas Montavon, Fabrice Darbellay, Sandra Gitto +1 more

    2014Science120 citations Open access

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15. Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs

    J. López-Ríos, A. Duchesne, D. Speziale, G. Andrey +19 more

    2014Nature112 citations Open access

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16. Hotair Is Dispensible for Mouse Development

    Ana Rita Amândio, A. Necsulea, E. Joye, Bénédicte Mascrez +1 more

    2016PLoS Genetics100 citations Open access

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17. Tail Bud Progenitor Activity Relies on a Network Comprising Gdf11, Lin28, and Hox13 Genes.

    Rita Aires, Luisa de Lemos, A. Nóvoa, A. D. Jurberg +3 more

    2019Developmental Cell95 citations Open access

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18. Role of a polymorphism in a Hox/Pax-responsive enhancer in the evolution of the vertebrate spine

    I. Guerreiro, Andreia M. Nunes, J. Woltering, Ana Casaca +5 more

    2013Proceedings of the National Academy of Sciences of the United States of America95 citations Open access

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19. Chromatin organization and global regulation of Hox gene clusters

    Thomas Montavon, D. Duboule

    2013Philosophical Transactions of the Royal Society B: Biological Sciences86 citations Open access

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20. Duplications of hox gene clusters and the emergence of vertebrates.

    N. Soshnikova, R. Dewaele, P. Janvier, R. Krumlauf +1 more

    2013Developmental Biology82 citations Open access

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21. A role for HOX13 proteins in the regulatory switch between TADs at the HoxD locus

    L. Beccari, Nayuta Yakushiji-Kaminatsui, J. Woltering, A. Necsulea +6 more

    2016Genes & Development81 citations Open access

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22. Nanoscale spatial organization of the HoxD gene cluster in distinct transcriptional states

    P. Fabre, Alexander Benke, E. Joye, Thi Hanh Nguyen Huynh +2 more

    2015Proceedings of the National Academy of Sciences of the United States of America79 citations Open access

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23. A genetic approach to the transcriptional regulation of Hox gene clusters.

    P. Tschopp, D. Duboule

    2011Annual Review of Genetics77 citations Open access

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24. Multiple enhancers regulate Hoxd genes and the Hotdog LncRNA during cecum budding.

    Saskia Delpretti, Thomas Montavon, M. Leleu, E. Joye +3 more

    2013Cell Reports72 citations Open access

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25. A regulatory 'landscape effect' over the HoxD cluster.

    P. Tschopp, D. Duboule

    2011Developmental Biology65 citations Open access

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26. Evolving Hox Activity Profiles Govern Diversity in Locomotor Systems

    Heekyung Jung, E. Mazzoni, N. Soshnikova, Olivia Hanley +3 more

    2014Developmental Cell58 citations Open access

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27. The regulatory landscapes of developmental genes

    C. C. Bolt, D. Duboule

    2020Development57 citations Open access

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28. Chromatin topology and the timing of enhancer function at the HoxD locus

    Eddie Rodríguez-Carballo, Lucille Lopez-Delisle, Andréa Willemin, L. Beccari +3 more

    2020Proceedings of the National Academy of Sciences of the United States of America54 citations Open access

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29. Chromatin architectures and Hox gene collinearity.

    D. Noordermeer, D. Duboule

    2013Current Topics in Developmental Biology52 citations Open access

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30. Landscapes and archipelagos: spatial organization of gene regulation in vertebrates.

    Thomas Montavon, D. Duboule

    2012Trends in Cell Biology52 citations Open access

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31. Noncoding copy-number variations are associated with congenital limb malformation

    Ricarda Flöttmann, Bjørt K. Kragesteen, Sinje Geuer, Magdalena Socha +23 more

    2017Genetics in Medicine49 citations Open access

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32. Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos

    Hocine Rekaik, Lucille Lopez-Delisle, Aurélie Hintermann, Bénédicte Mascrez +3 more

    2023Nature Genetics45 citations Open access

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33. Structure, function and evolution of topologically associating domains (TADs) atHOX loci

    Nicolas Lonfat, D. Duboule

    2015FEBS Letters45 citations Open access

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34. The constrained architecture of mammalian Hox gene clusters

    Fabrice Darbellay, Célia Bochaton, Lucille Lopez-Delisle, Bénédicte Mascrez +4 more

    2019Proceedings of the National Academy of Sciences of the United States of America42 citations Open access

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35. Sequential in cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster

    Ana Rita Amândio, L. Beccari, Lucille Lopez-Delisle, Bénédicte Mascrez +3 more

    2021bioRxiv40 citations Open access

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36. Impact of copy number variations (CNVs) on long-range gene regulation at the HoxD locus

    Thomas Montavon, Laurie Thevenet, D. Duboule

    2012Proceedings of the National Academy of Sciences of the United States of America40 citations Open access

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37. A Genetic Approach to the Recruitment of PRC2 at the HoxD Locus

    Patrick Schorderet, Nicolas Lonfat, Fabrice Darbellay, P. Tschopp +3 more

    2013PLoS Genetics36 citations Open access

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38. Topological Domains, Metagenes, and the Emergence of Pleiotropic Regulations at Hox Loci.

    Fabrice Darbellay, D. Duboule

    2016Current Topics in Developmental Biology33 citations Open access

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39. Control of Hoxd gene transcription in the mammary bud by hijacking a preexisting regulatory landscape

    Ruben Schep, A. Necsulea, Eddie Rodríguez-Carballo, I. Guerreiro +6 more

    2016Proceedings of the National Academy of Sciences of the United States of America32 citations Open access

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40. Similarities and differences in the regulation of HoxD genes during chick and mouse limb development

    Nayuta Yakushiji-Kaminatsui, Lucille Lopez-Delisle, C. C. Bolt, G. Andrey +2 more

    2018PLoS Biology31 citations Open access

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41. Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan

    I. Guerreiro, Sandra Gitto, A. Nóvoa, Julien Codourey +5 more

    2016eLife30 citations Open access

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42. Integration of Shh and Fgf signaling in controlling Hox gene expression in cultured limb cells

    Alan R Rodrigues, Nayuta Yakushiji-Kaminatsui, Y. Atsuta, G. Andrey +3 more

    2017Proceedings of the National Academy of Sciences of the United States of America28 citations Open access

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43. Essay the (unusual) heuristic value of Hox gene clusters; a matter of time?

    D. Duboule

    2022Developmental Biology27 citations Open access

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44. Analysis of Polycerate Mutants Reveals the Evolutionary Co-option of HOXD1 for Horn Patterning in Bovidae

    A. Allais-Bonnet, Aurélie Hintermann, M. Deloche, R. Cornette +44 more

    2021Molecular biology and evolution27 citations Open access

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45. Large scale genomic reorganization of topological domains at the HoxD locus

    P. Fabre, M. Leleu, Benjamin Mormann, Lucille Lopez-Delisle +3 more

    2017Genome Biology27 citations Open access

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46. Mammalian-specific ectodermal enhancers control the expression of Hoxc genes in developing nails and hair follicles

    M. Fernández-Guerrero, Nayuta Yakushiji-Kaminatsui, Lucille Lopez-Delisle, Sofía Zdral +6 more

    2020Proceedings of the National Academy of Sciences of the United States of America26 citations Open access

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47. Visualizing the HoxD Gene Cluster at the Nanoscale Level.

    P. Fabre, Alexander Benke, S. Manley, D. Duboule

    2015Cold Spring Harbor Symposia on Quantitative Biology25 citations Open access

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48. A complex regulatory landscape involved in the development of mammalian external genitals

    Ana Rita Amândio, Lucille Lopez-Delisle, C. C. Bolt, Bénédicte Mascrez +1 more

    2020eLife24 citations Open access

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49. A function for all posterior Hoxd genes during digit development?

    Saskia Delpretti, J. Zákány, D. Duboule

    2012Developmental Dynamics24 citations Open access

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50. Dbx2 regulation in limbs suggests interTAD sharing of enhancers

    L. Beccari, Gabriel Jaquier, Lucille Lopez-Delisle, Eddie Rodríguez-Carballo +4 more

    2020bioRxiv23 citations Open access

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