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F. Di Virgilio · SciRah

Researcher profile · Semantic Scholar

F. Di Virgilio

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F. Di Virgilio — researcher profile on SciRah

h-index: 115
Works: 499
Citations: 47K

Most-cited papers

From purines to purinergic signalling: molecular functions and human diseases
Zhao Huang, N. Xie, P. Illés, F. Di Virgilio +7 more
2021Signal Transduction and Targeted Therapy446 citations Open access
Semantic Scholar
Apoptotic cell death in disease—Current understanding of the NCCD 2023
I. Vitale, F. Pietrocola, E. Guilbaud, S. Aaronson +224 more
2023Cell Death and Differentiation346 citations Open access
Semantic Scholar
THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels
Stephen P. H. Alexander, A. Mathie, J. A. Peters, E. Veale +48 more
2019British Journal of Pharmacology294 citations Open access
Semantic Scholar
Update of P2X receptor properties and their pharmacology: IUPHAR Review 30
P. Illés, Christa E. Müller, K. Jacobson, T. Grutter +8 more
2020British Journal of Pharmacology263 citations Open access
Semantic Scholar
The Concise Guide to PHARMACOLOGY 2023/24: Ion channels
Stephen P. H. Alexander, A. Mathie, John A. Peters, E. Veale +69 more
2023British Journal of Pharmacology254 citations Open access
Semantic Scholar
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels
Stephen P. H. Alexander, A. Mathie, J. A. Peters, E. Veale +54 more
2021British Journal of Pharmacology224 citations Open access
Semantic Scholar
Extracellular ATP: A Feasible Target for Cancer Therapy
Valentina Vultaggio-Poma, A. Sarti, F. Di Virgilio
2020Cells224 citations Open access
Semantic Scholar
ATP and cancer immunosurveillance
O. Kepp, L. Bezu, T. Yamazaki, F. Di Virgilio +3 more
2021EMBO Journal202 citations Open access
Semantic Scholar
Purinergic signalling, DAMPs and inflammation.
F. Di Virgilio, A. Sarti, R. Coutinho-Silva
2020American Journal of Physiology - Cell Physiology196 citations Open access
Semantic Scholar
The P2X7 receptor modulates immune cells infiltration, ectonucleotidases expression and extracellular ATP levels in the tumor microenvironment
E. De Marchi, E. Orioli, Anna Pegoraro, S. Sangaletti +5 more
2019Oncogene177 citations Open access
Semantic Scholar
P2X7 in Cancer: From Molecular Mechanisms to Therapeutics
R. Lara, E. Adinolfi, C. Harwood, M. Philpott +3 more
2020Frontiers in Pharmacology156 citations Open access
Semantic Scholar
Intercellular Calcium Signaling Induced by ATP Potentiates Macrophage Phagocytosis
S. Zumerle, B. Calì, F. Munari, R. Angioni +3 more
2019Cell Reports114 citations Open access
Semantic Scholar
Extracellular ATP: A powerful inflammatory mediator in the central nervous system.
F. Di Virgilio, Valentina Vultaggio-Poma, S. Falzoni, A. Giuliani
2022Neuropharmacology88 citations Open access
Semantic Scholar
The Concise Guide to PHARMACOLOGY 2025/26: Ion channels
Stephen P. H. Alexander, Jörg Striessnig, Alasdair J. Gibb, A. Mathie +83 more
2025British Journal of Pharmacology80 citations Open access
Semantic Scholar
P2X7 promotes metastatic spreading and triggers release of miRNA-containing exosomes and microvesicles from melanoma cells
Anna Pegoraro, E. De Marchi, M. Ferracin, E. Orioli +8 more
2021Cell Death and Disease72 citations Open access
Semantic Scholar
Ectonucleotidases in Acute and Chronic Inflammation
A. Giuliani, A. Sarti, F. Di Virgilio
2021Frontiers in Pharmacology69 citations Open access
Semantic Scholar
Amyloid β-dependent mitochondrial toxicity in mouse microglia requires P2X7 receptor expression and is prevented by nimodipine
P. Chiozzi, A. Sarti, J. M. Sanz, A. Giuliani +4 more
2019Scientific Reports69 citations Open access
Semantic Scholar
Molecular Mechanisms Related to Oxidative Stress in Retinitis Pigmentosa
C. Gallenga, Maria Lonardi, S. Pacetti, S. Violanti +4 more
2021Antioxidants67 citations Open access
Semantic Scholar
Irradiation causes senescence, ATP release, and P2X7 receptor isoform switch in glioblastoma
M. Zanoni, A. Sarti, A. Zamagni, M. Cortesi +10 more
2022Cell Death and Disease57 citations Open access
Semantic Scholar
A rationale for targeting the P2X7 receptor in Coronavirus disease 19
F. Di Virgilio, Yong Tang, A. Sarti, M. Rossato
2020British Journal of Pharmacology55 citations Open access
Semantic Scholar
Mitochondrial P2X7 Receptor Localization Modulates Energy Metabolism Enhancing Physical Performance
A. Sarti, Valentina Vultaggio-Poma, S. Falzoni, S. Missiroli +14 more
2021Function54 citations Open access
Semantic Scholar
Differential sensitivity of acute myeloid leukemia cells to daunorubicin depends on P2X7A versus P2X7B receptor expression
Anna Pegoraro, E. Orioli, E. De Marchi, Valentina Salvestrini +4 more
2020Cell Death and Disease53 citations Open access
Semantic Scholar
P2X7 receptor activity limits accumulation of T cells within tumors
Andrea Romagnani, E. Rottoli, E. Mazza, Tanja Rezzonico-Jost +14 more
2020Cancer Research51 citations Open access
Semantic Scholar
Blocking P2X7 by intracerebroventricular injection of P2X7-specific nanobodies reduces stroke lesions
Maximilian Wilmes, Carolina Pinto Espinoza, P. Ludewig, Joschi Stabernack +11 more
2022Journal of Neuroinflammation47 citations Open access
Semantic Scholar
Signalling by extracellular nucleotides in health and disease.
Valentina Vultaggio-Poma, S. Falzoni, G. Salvi, A. Giuliani +1 more
2022Biochimica et biophysica acta. Molecular cell research47 citations Open access
Semantic Scholar
PML at mitochondria-associated membranes governs a trimeric complex with NLRP3 and P2X7R that modulates the tumor immune microenvironment
S. Missiroli, M. Perrone, R. Gafà, F. Nicoli +16 more
2022Cell Death and Differentiation45 citations Open access
Semantic Scholar
Astrocytes‐derived extracellular vesicles in motion at the neuron surface: Involvement of the prion protein
G. D'arrigo, M. Gabrielli, Federica Scaroni, P. Swuec +7 more
2021Journal of Extracellular Vesicles43 citations Open access
Semantic Scholar
The P2X7 Receptor Is Shed Into Circulation: Correlation With C-Reactive Protein Levels
A. Giuliani, Merhej Berchan, J. M. Sanz, A. Passaro +4 more
2019Frontiers in Immunology41 citations Open access
Semantic Scholar
P2X receptors in cancer growth and progression.
F. Di Virgilio, Valentina Vultaggio-Poma, A. Sarti
2020Biochemical Pharmacology40 citations
Semantic Scholar
Extracellular ATP is increased by release of ATP-loaded microparticles triggered by nutrient deprivation
Valentina Vultaggio-Poma, S. Falzoni, P. Chiozzi, A. Sarti +8 more
2022Theranostics38 citations Open access
Semantic Scholar
P2X7 Receptor Expression in Patients With Serositis Related to Systemic Lupus Erythematosus
F. Furini, A. Giuliani, Mattia Erminio Parlati, M. Govoni +2 more
2019Frontiers in Pharmacology37 citations Open access
Semantic Scholar
Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells
Valentina Salvestrini, M. Ciciarello, Valentina Pensato, G. Simonetti +13 more
2020Frontiers in Oncology34 citations Open access
Semantic Scholar
Role of the P2X7 receptor in in vitro and in vivo glioma tumor growth
L. Bergamin, Marina Capece, Erica Salaro, A. Sarti +6 more
2019OncoTarget32 citations Open access
Semantic Scholar
Detection of Extracellular ATP in the Tumor Microenvironment, Using the pmeLUC Biosensor.
E. De Marchi, E. Orioli, Anna Pegoraro, E. Adinolfi +1 more
2020Methods in molecular biology30 citations
Semantic Scholar
The P2X7 Receptor: A Promising Pharmacological Target in Diabetic Retinopathy
Matteo Tassetto, A. Scialdone, A. Solini, F. Di Virgilio
2021International Journal of Molecular Sciences24 citations Open access
Semantic Scholar
The P2X7 Receptor 489C>T Gain of Function Polymorphism Favors HHV-6A Infection and Associates With Female Idiopathic Infertility
Anna Pegoraro, D. Bortolotti, R. Marci, E. Caselli +5 more
2020Frontiers in Pharmacology24 citations Open access
Semantic Scholar
In Vivo Detection of Extracellular Adenosine Triphosphate in a Mouse Model of Traumatic Brain Injury
Ayman H. Faroqi, Melina J. Lim, E. C. Kee, Jannifer H. Lee +5 more
2020Journal of Neurotrauma24 citations Open access
Semantic Scholar
Purinergic signalling in cancer therapeutic resistance: From mechanisms to targeting strategies.
Wen-Hui Jia, Zhao Huang, Li Zhou, Y. Liou +6 more
2023Drug resistance updates23 citations Open access
Semantic Scholar
A3 Adenosine and P2X7 Purinergic Receptors as New Targets for an Innovative Pharmacological Therapy of Malignant Pleural Mesothelioma
F. Vincenzi, J. Rotondo, Silvia Pasquini, F. Di Virgilio +2 more
2021Frontiers in Oncology22 citations Open access
Semantic Scholar
The P2X7 Receptor is a Master Regulator of Microparticle and Mitochondria Exchange in Mouse Microglia
S. Falzoni, Valentina Vultaggio-Poma, P. Chiozzi, Mario Tarantini +7 more
2024Function21 citations Open access
Semantic Scholar
The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties
Luke Tattersall, Karan M. Shah, D. Lath, Archana Singh +10 more
2021bioRxiv21 citations Open access
Semantic Scholar
Overview of the role of purinergic signaling and insights into its role in cancer therapy.
F. Di Virgilio, Valentina Vultaggio-Poma, Mario Tarantini, Anna Lisa Giuliani
2024Pharmacology and Therapeutics19 citations Open access
Semantic Scholar
The Coming of Age of the P2X7 Receptor in Diagnostic Medicine
F. Di Virgilio, Valentina Vultaggio-Poma, S. Falzoni, A. Giuliani
2023International Journal of Molecular Sciences19 citations Open access
Semantic Scholar
Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering A2BAR signaling in intestinal epithelial cells
Darine W El-Naccache, Fei Chen, Mark J. Palma, A. Lemenze +10 more
2022Cell Reports19 citations Open access
Semantic Scholar
A2A Receptor Contributes to Tumor Progression in P2X7 Null Mice
E. De Marchi, Anna Pegoraro, Roberta Turiello, F. Di Virgilio +2 more
2022bioRxiv18 citations Open access
Semantic Scholar
P2X7 a new therapeutic target to block vesicle-dependent metastasis in colon carcinoma: Role of the A2A/CD39/CD73 axis
Anna Pegoraro, E. De Marchi, L. Ruo, Michele Zanoni +10 more
2025Cell Death and Disease17 citations Open access
Semantic Scholar
P2X7 receptor is essential for cross-dressing of bone marrow-derived dendritic cells
C. Barrera-Avalos, P. Briceño, Daniel Valdés, M. Imarai +10 more
2021iScience17 citations Open access
Semantic Scholar
Expression and function of the P2X7 receptor in human osteoblasts: The role of NFATc1 transcription factor
L. Bergamin, L. Penolazzi, E. Lambertini, S. Falzoni +6 more
2020Journal of Cellular Physiology15 citations
Semantic Scholar
Fetal bovine serum contains biologically available ATP
Valentina Vultaggio-Poma, Leticia Scussel Bergamin, S. Falzoni, M. Tarantini +4 more
2023Purinergic Signalling Purinergic Signalling14 citations Open access
Semantic Scholar
The shed P2X7 receptor is an index of adverse clinical outcome in COVID-19 patients
Valentina Vultaggio-Poma, J. M. Sanz, A. Amico, A. Violi +7 more
2023Frontiers in Immunology14 citations Open access
Semantic Scholar

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