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M. Tortoreto · SciRah

Researcher profile · Semantic Scholar

M. Tortoreto

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M. Tortoreto — researcher profile on SciRah

h-index: 33
Works: 119
Citations: 3,997

Most-cited papers

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment
Giulia Bertolini, L. Roz, P. Perego, M. Tortoreto +15 more
2009Proceedings of the National Academy of Sciences of the United States of America827 citations Open access
Semantic Scholar
SST0001, a chemically modified heparin, inhibits myeloma growth and angiogenesis via disruption of the heparanase/syndecan-1 axis
J. Ritchie, V. Ramani, Yong-Sheng Ren, A. Naggi +10 more
2011Clinical Cancer Research236 citations Open access
Semantic Scholar
TNF-Related Apoptosis-Inducing Ligand (TRAIL)–Armed Exosomes Deliver Proapoptotic Signals to Tumor Site
L. Rivoltini, C. Chiodoni, P. Squarcina, M. Tortoreto +16 more
2016Clinical Cancer Research174 citations Open access
Semantic Scholar
Oncosuppressive role of p53-induced miR-205 in triple negative breast cancer
C. Piovan, D. Palmieri, G. di Leva, L. Braccioli +10 more
2012Molecular Oncology173 citations Open access
Semantic Scholar
REST Controls Self-Renewal and Tumorigenic Competence of Human Glioblastoma Cells
L. Conti, L. Crisafulli, V. Caldera, M. Tortoreto +6 more
2012PLoS ONE108 citations Open access
Semantic Scholar
Microenvironment-Modulated Metastatic CD133+/CXCR4+/EpCAM- Lung Cancer-Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis.
Giulia Bertolini, L. D'Amico, M. Moro, E. Landoni +14 more
2015Cancer Research95 citations Open access
Semantic Scholar
Patient-Derived Xenografts of Non Small Cell Lung Cancer: Resurgence of an Old Model for Investigation of Modern Concepts of Tailored Therapy and Cancer Stem Cells
M. Moro, Giulia Bertolini, M. Tortoreto, U. Pastorino +2 more
2012Journal of Biomedicine and Biotechnology91 citations Open access
Semantic Scholar
Heterogeneous phenotype of human melanoma cells with in vitro and in vivo features of tumor-initiating cells.
Michela Perego, M. Tortoreto, G. Tragni, L. Mariani +14 more
2010Journal of Investigative Dermatology83 citations Open access
Semantic Scholar
Antitumor efficacy of the heparanase inhibitor SST0001 alone and in combination with antiangiogenic agents in the treatment of human pediatric sarcoma models.
G. Cassinelli, C. Lanzi, M. Tortoreto, D. Cominetti +7 more
2013Biochemical Pharmacology77 citations
Semantic Scholar
Dacarbazine in Solitary Fibrous Tumor: A Case Series Analysis and Preclinical Evidence vis-à-vis Temozolomide and Antiangiogenics
S. Stacchiotti, M. Tortoreto, F. Bozzi, E. Tamborini +10 more
2013Clinical Cancer Research77 citations Open access
Semantic Scholar
miR-205 enhances radiation sensitivity of prostate cancer cells by impairing DNA damage repair through PKCε and ZEB1 inhibition
R. El Bezawy, S. Tinelli, M. Tortoreto, V. Doldi +7 more
2019Journal of experimental & clinical cancer research : CR72 citations Open access
Semantic Scholar
XPO1/CRM1-Selective Inhibitors of Nuclear Export (SINE) reduce tumor spreading and improve overall survival in preclinical models of prostate cancer (PCa)
G. Gravina, M. Tortoreto, A. Mancini, A. Addis +8 more
2014Journal of Hematology & Oncology70 citations Open access
Semantic Scholar
Therapeutic synergism of gemcitabine and CpG-oligodeoxynucleotides in an orthotopic human pancreatic carcinoma xenograft.
G. Pratesi, G. Petrangolini, M. Tortoreto, A. Addis +6 more
2005Cancer Research69 citations Open access
Semantic Scholar
HSPH1 inhibition downregulates Bcl-6 and c-Myc and hampers the growth of human aggressive B-cell non-Hodgkin lymphoma.
R. Zappasodi, G. Ruggiero, C. Guarnotta, M. Tortoreto +11 more
2015Blood67 citations Open access
Semantic Scholar
Combination of a CpG-oligodeoxynucleotide and a topoisomerase I inhibitor in the therapy of human tumour xenografts.
A. Balsari, M. Tortoreto, D. Besusso, Giovanna Petrangolini +4 more
2004European Journal of Cancer57 citations
Semantic Scholar
Transplantation of autologous extracellular vesicles for cancer-specific targeting
A. Villa, Mariangela Garofalo, D. Crescenti, N. Rizzi +17 more
2021Theranostics50 citations Open access
Semantic Scholar
Serological identification of HSP105 as a novel non-Hodgkin lymphoma therapeutic target.
R. Zappasodi, I. Bongarzone, G. Ghedini, L. Castagnoli +9 more
2010Blood49 citations Open access
Semantic Scholar
Antitumor efficacy of the heparan sulfate mimic roneparstat (SST0001) against sarcoma models involves multi-target inhibition of receptor tyrosine kinases
G. Cassinelli, E. Favini, Laura Dal Bo, M. Tortoreto +6 more
2016OncoTarget48 citations Open access
Semantic Scholar
Effect of a Novel Vacuolar-H+-ATPase Inhibitor on Cell and Tumor Response to Camptothecins
G. Petrangolini, R. Supino, G. Pratesi, Laura Dal Bo +6 more
2006Journal of Pharmacology and Experimental Therapeutics44 citations
Semantic Scholar
Inhibition of c-Met and prevention of spontaneous metastatic spreading by the 2-indolinone RPI-1
G. Cassinelli, C. Lanzi, G. Petrangolini, M. Tortoreto +8 more
2006Molecular Cancer Therapeutics43 citations Open access
Semantic Scholar
Poly(I:C) and CpG-ODN combined aerosolization to treat lung metastases and counter the immunosuppressive microenvironment
V. Le Noci, M. Tortoreto, A. Gulino, Chiara Storti +6 more
2015Oncoimmunology39 citations Open access
Semantic Scholar
PDGFRβ and FGFR2 mediate endothelial cell differentiation capability of triple negative breast carcinoma cells
I. Plantamura, P. Casalini, E. Dugnani, M. Sasso +14 more
2014Molecular Oncology39 citations Open access
Semantic Scholar
Apoptotic cell death induction and angiogenesis inhibition in large established medullary thyroid carcinoma xenografts by Ret inhibitor RPI-1.
G. Petrangolini, G. Cuccuru, C. Lanzi, M. Tortoreto +4 more
2006Biochemical Pharmacology39 citations
Semantic Scholar
Antimetastatic Effect of a Small-Molecule Vacuolar H+-ATPase Inhibitor in in Vitro and in Vivo Preclinical Studies
R. Supino, G. Petrangolini, G. Pratesi, M. Tortoreto +9 more
2008Journal of Pharmacology and Experimental Therapeutics38 citations
Semantic Scholar
Antisecretive and Antitumor Activity of Abiraterone Acetate in Human Adrenocortical Cancer: A Preclinical Study.
C. Fiorentini, M. Fragni, P. Perego, S. Vezzoli +12 more
2016Journal of Clinical Endocrinology and Metabolism35 citations Open access
Semantic Scholar
Reprogramming the lung microenvironment by inhaled immunotherapy fosters immune destruction of tumor
V. Le Noci, M. Sommariva, M. Tortoreto, N. Zaffaroni +4 more
2016Oncoimmunology35 citations Open access
Semantic Scholar
Shed HER2 extracellular domain in HER2‐mediated tumor growth and in trastuzumab susceptibility
G. Ghedini, V. Ciravolo, M. Tortoreto, S. Giuffré +12 more
2010Journal of Cellular Physiology34 citations
Semantic Scholar
The curative efficacy of namitecan (ST1968) in preclinical models of pediatric sarcoma is associated with antiangiogenic effects.
G. Cassinelli, V. Zuco, G. Petrangolini, M. de Cesare +12 more
2012Biochemical Pharmacology32 citations
Semantic Scholar
Pharmacogenomics and analogues of the antitumour agent N6‐isopentenyladenosine
F. Colombo, F. Falvella, L. De Cecco, M. Tortoreto +7 more
2009International Journal of Cancer31 citations Open access
Semantic Scholar
Supersulfated low-molecular weight heparin synergizes with IGF1R/IR inhibitor to suppress synovial sarcoma growth and metastases.
G. Cassinelli, Laura Dal Bo, E. Favini, D. Cominetti +10 more
2018Cancer Letters29 citations
Semantic Scholar
Selinexor versus doxorubicin in dedifferentiated liposarcoma PDXs: evidence of greater activity and apoptotic response dependent on p53 nuclear accumulation and survivin down‐regulation
V. Zuco, S. Pasquali, M. Tortoreto, S. Brich +13 more
2021Journal of experimental & clinical cancer research : CR27 citations Open access
Semantic Scholar
Metabolic Approach to the Enhancement of Antitumor Effect of Chemotherapy: a Key Role of Acetyl-l-Carnitine
C. Pisano, L. Vesci, F. Milazzo, M. Guglielmi +13 more
2010Clinical Cancer Research27 citations Open access
Semantic Scholar
Synergistic cooperation between sunitinib and cisplatin promotes apoptotic cell death in human medullary thyroid cancer.
Alessia Lopergolo, Valentina Nicolini, E. Favini, Laura Dal Bo +10 more
2014Journal of Clinical Endocrinology and Metabolism26 citations
Semantic Scholar
Comparative Assessment of Antitumor Effects and Autophagy Induction as a Resistance Mechanism by Cytotoxics and EZH2 Inhibition in INI1-Negative Epithelioid Sarcoma Patient-Derived Xenograft
S. Stacchiotti, V. Zuco, M. Tortoreto, D. Cominetti +17 more
2019Cancers24 citations Open access
Semantic Scholar
Targeting the invasive phenotype of cisplatin-resistant non-small cell lung cancer cells by a novel histone deacetylase inhibitor.
V. Zuco, G. Cassinelli, G. Cossa, L. Gatti +11 more
2015Biochemical Pharmacology24 citations
Semantic Scholar
Targeting of RET oncogene by naphthalene diimide-mediated gene promoter G-quadruplex stabilization exerts anti-tumor activity in oncogene-addicted human medullary thyroid cancer
Alessia Lopergolo, R. Perrone, M. Tortoreto, F. Doria +8 more
2016OncoTarget23 citations Open access
Semantic Scholar
Efficacy of ST1968 (namitecan) on a topotecan-resistant squamous cell carcinoma.
V. Zuco, R. Supino, E. Favini, M. Tortoreto +5 more
2010Biochemical Pharmacology22 citations Open access
Semantic Scholar
Upregulation of ERK-EGR1-heparanase axis by HDAC inhibitors provides targets for rational therapeutic intervention in synovial sarcoma
C. Lanzi, E. Favini, Laura Dal Bo, M. Tortoreto +3 more
2021Journal of experimental & clinical cancer research : CR21 citations Open access
Semantic Scholar
Anti‐tumor activity of CpG‐ODN aerosol in mouse lung metastases
L. Sfondrini, M. Sommariva, M. Tortoreto, A. Meini +8 more
2013International Journal of Cancer21 citations Open access
Semantic Scholar
Antitumour and antiangiogenic effects of IDN 5390, a novel C-seco taxane, in a paclitaxel-resistant human ovarian tumour xenograft
Giovanna Petrangolini, G. Cassinelli, G. Pratesi, M. Tortoreto +5 more
2004British Journal of Cancer21 citations Open access
Semantic Scholar
Pleiotropic antitumor effects of the pan‐HDAC inhibitor ITF2357 against c‐Myc‐overexpressing human B‐cell non‐Hodgkin lymphomas
R. Zappasodi, Alessandra Cavané, M. Iorio, M. Tortoreto +10 more
2014International Journal of Cancer20 citations Open access
Semantic Scholar
A novel CXCR4 antagonist counteracts paradoxical generation of cisplatin-induced pro-metastatic niches in lung cancer
Giulia Bertolini, V. Cancila, M. Milione, Giuseppe Lo Russo +18 more
2021Molecular Therapy18 citations Open access
Semantic Scholar
Microenvironment modulation and enhancement of antilymphoma therapy by the heparanase inhibitor roneparstat
A. Rossini, F. Zunino, G. Ruggiero, M. de Cesare +9 more
2018Hematological Oncology16 citations
Semantic Scholar
[18F]FDG and [18F]FLT PET for the evaluation of response to neo-adjuvant chemotherapy in a model of triple negative breast cancer
I. Raccagni, S. Belloli, S. Valtorta, Alessandro Stefano +9 more
2018PLoS ONE16 citations Open access
Semantic Scholar
Maspin influences response to doxorubicin by changing the tumor microenvironment organization
T. Triulzi, Manuela Ratti, M. Tortoreto, C. Ghirelli +9 more
2014International Journal of Cancer16 citations Open access
Semantic Scholar
SPOP Deregulation Improves the Radiation Response of Prostate Cancer Models by Impairing DNA Damage Repair
R. El Bezawy, Martina Tripari, Stefano Percio, A. Cicchetti +8 more
2020Cancers15 citations Open access
Semantic Scholar
Interplay between Ret and Fap-1 regulates CD95-mediated apoptosis in medullary thyroid cancer cells.
Valentina Nicolini, G. Cassinelli, G. Cuccuru, I. Bongarzone +8 more
2011Biochemical Pharmacology15 citations
Semantic Scholar
Antitumor Efficacy of Trastuzumab in Nude Mice Orthotopically Xenografted With Human Pancreatic Tumor Cells Expressing Low Levels of HER-2/neu
G. Pratesi, G. Petrangolini, M. Tortoreto, A. Addis +6 more
2008Journal of immunotherapy15 citations
Semantic Scholar
miR-34a-Mediated Survivin Inhibition Improves the Antitumor Activity of Selinexor in Triple-Negative Breast Cancer
Silvia Martini, V. Zuco, M. Tortoreto, Stefano Percio +6 more
2021Pharmaceuticals14 citations Open access
Semantic Scholar
Biological properties of IDN5174, a new synthetic camptothecin with the open lactone ring.
G. Beretta, G. Petrangolini, M. de Cesare, G. Pratesi +12 more
2006Cancer Research14 citations
Semantic Scholar

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N. Zaffaroni×26
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N. Zaffaroni — researcher profile on SciRah
F. Zunino×16
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C. Lanzi×13
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C. Lanzi — researcher profile on SciRah
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G. Cassinelli — researcher profile on SciRah

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G. Petrangolini — researcher profile on SciRah

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