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C. Tinkle · SciRah

Researcher profile · Semantic Scholar

C. Tinkle

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C. Tinkle — researcher profile on SciRah

h-index: 22
Works: 137
Citations: 3,149

Most-cited papers

Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression
Jon D. Larson, Lawryn H. Kasper, Barbara S. Paugh, Hong-Jian Jin +22 more
2018Cancer Cell252 citations Open access
Semantic Scholar
Molecular Grouping and Outcomes of Young Children with Newly Diagnosed Ependymoma Treated on the Multi-Institutional SJYC07 Trial.
S. Upadhyaya, G. Robinson, A. Onar-Thomas, Brent A. Orr +20 more
2019Neuro-Oncology72 citations Open access
Semantic Scholar
Late effects of radiation therapy in pediatric patients and survivorship
J. Palmer, D. Tsang, C. Tinkle, A. Olch +4 more
2021Pediatric Blood & Cancer67 citations Open access
Semantic Scholar
A single-center study of the clinicopathologic correlates of gliomas with a MYB or MYBL1 alteration
J. Chiang, J. Harreld, C. Tinkle, Daniel C. Moreira +4 more
2019Acta Neuropathologica60 citations Open access
Semantic Scholar
Association between hippocampal dose and memory in survivors of childhood or adolescent low-grade glioma: a 10-year neurocognitive longitudinal study
S. Acharya, Sheng-Jie Wu, J. Ashford, C. Tinkle +6 more
2019Neuro-Oncology59 citations Open access
Semantic Scholar
Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma
Chen He, Ke Xu, Xiao-Yan Zhu, P. Dunphy +36 more
2021Nature Communications51 citations Open access
Semantic Scholar
Clinical, imaging, and molecular analysis of pediatric pontine tumors lacking characteristic imaging features of DIPG
J. Chiang, Alexander K. Diaz, L. Makepeace, Xiaoyu Li +11 more
2020Acta Neuropathologica Communications48 citations Open access
Semantic Scholar
Assessment and Treatment Outcomes of Persistent Radiation-Induced Alopecia in Patients With Cancer.
G. S. Phillips, M. Freret, D. Friedman, S. Trelles +11 more
2020JAMA dermatology38 citations Open access
Semantic Scholar
Late Infection-Related Mortality in Asplenic Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study.
Brent R. Weil, Arin L. Madenci, Qi Liu, R. Howell +13 more
2018Journal of Clinical Oncology37 citations Open access
Semantic Scholar
Response assessment in pediatric craniopharyngioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group.
L. Hoffman, C. Jaimes, K. Mankad, D. Mirsky +20 more
2022Neuro-Oncology28 citations Open access
Semantic Scholar
Evaluation of 11C-Methionine PET and Anatomic MRI Associations in Diffuse Intrinsic Pontine Glioma
C. Tinkle, Elizabeth C. Duncan, M. Doubrovin, Yuan-yuan Han +6 more
2018Journal of Nuclear Medicine28 citations Open access
Semantic Scholar
Molecular classification and outcome of children with rare CNS embryonal tumors: Results from St. Jude Children’s Research Hospital including the multi-center SJYC07 and SJMB03 clinical trials
Anthony P. Y. Liu, S. Dhanda, Tong Lin, Edgar Sioson +33 more
2022Acta Neuropathologica26 citations Open access
Semantic Scholar
Radiomics Features Differentiate Between Normal and Tumoral High-Fdg Uptake
Chih-Yang Hsu, Michael Doubrovin, C. Hua, Omar Mohammed +8 more
2018Scientific Reports26 citations Open access
Semantic Scholar
Safety and efficacy of brainstem biopsy in children and young adults.
David S. Hersh, Rahul Kumar, Kenneth A. Moore, Luke G. F. Smith +8 more
2020Journal of Neurosurgery: Pediatrics24 citations
Semantic Scholar
DNA damage response in brain tumors: A Society for Neuro-Oncology consensus review on mechanisms and translational efforts in neuro-oncology.
R. Rahman, Diana Shi, Z. Reitman, Petra Hamerlik +11 more
2024Neuro-Oncology23 citations Open access
Semantic Scholar
Phase I study using crenolanib to target PDGFR kinase in children and young adults with newly diagnosed DIPG or recurrent high-grade glioma, including DIPG
C. Tinkle, A. Broniscer, J. Chiang, O. Campagne +12 more
2021Neuro-Oncology Advances22 citations Open access
Semantic Scholar
Curative-intent radiotherapy for pediatric osteosarcoma: the St. Jude experience
C. Tinkle, Jason Lu, Yuan-yuan Han, Yi-Mei Li +4 more
2019Pediatric Blood & Cancer22 citations Open access
Semantic Scholar
ATM inhibition enhances the efficacy of radiation across distinct molecular subgroups of pediatric high-grade glioma.
Jia Xie, T. Kuriakose, B. Bianski, Nathaniel R. Twarog +20 more
2023Neuro-Oncology19 citations Open access
Semantic Scholar
Stereotactic body radiotherapy for metastatic and recurrent solid tumors in children and young adults
C. Tinkle, C. Singh, S. Lloyd, Yian Guo +8 more
2020International Journal of Radiation Oncology, Biology, Physics18 citations Open access
Semantic Scholar
PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma
Ryan J. Duchatel, Evangeline R. Jackson, Sarah Parackal, C. Sun +35 more
2023bioRxiv16 citations Open access
Semantic Scholar
Accuracy of Central Neuro-Imaging Review of DIPG Compared with Histopathology in the International DIPG Registry.
M. Lazow, C. Fuller, M. DeWire, A. Lane +44 more
2021Neuro-Oncology16 citations Open access
Semantic Scholar
MRI Patterns of Extrapontine Lesion Extension in Diffuse Intrinsic Pontine Gliomas
L. Makepeace, Matthew A. Scoggins, Bogdan G. Mitrea, Yu-Xin Li +5 more
2020American Journal of Neuroradiology16 citations Open access
Semantic Scholar
SLFN11 is widely expressed in pediatric sarcoma and induces variable sensitization to replicative stress caused by DNA damaging agents
J. Gartrell, M. Mellado-Largarde, Michael R. Clay, A. Bahrami +17 more
2021Molecular Cancer Therapeutics15 citations Open access
Semantic Scholar
Defining Optimal Target Volumes of Conformal Radiation Therapy for Diffuse Intrinsic Pontine Glioma
C. Tinkle, B. Simone, J. Chiang, Xiaoyu Li +11 more
2019International Journal of Radiation Oncology, Biology, Physics15 citations Open access
Semantic Scholar
Using response surface models to analyze drug combinations
Nathaniel R. Twarog, Nancy E. Martinez, J. Gartrell, Jia Xie +2 more
2021Drug Discovery Today13 citations Open access
Semantic Scholar
Preclinical Models of Craniospinal Irradiation for Medulloblastoma
Jennifer L. Stripay, T. Merchant, M. Roussel, C. Tinkle
2020Cancers13 citations Open access
Semantic Scholar
Preclinical Modeling of Image-Guided Craniospinal Irradiation for Very-High-Risk Medulloblastoma
Stephanie M. C. Smith, B. Bianski, Brent A. Orr, G. Harknett +5 more
2018International Journal of Radiation Oncology, Biology, Physics13 citations Open access
Semantic Scholar
Efficacy and Safety of Stereotactic Body Radiation Therapy for Pediatric Malignancies: The LITE-SABR Systematic Review and Meta-Analysis
Raj Singh, A. Valluri, Prabhanjan Didwania, E. Lehrer +8 more
2023Advances in Radiation Oncology11 citations Open access
Semantic Scholar
Efficacy and Safety of Limited-Margin Conformal Radiation Therapy for Pediatric Rhabdomyosarcoma: Long-Term Results of a Phase 2 Study
C. Tinkle, A. Pappo, Jian-Rong Wu, S. Mao +11 more
2020International Journal of Radiation Oncology, Biology, Physics11 citations Open access
Semantic Scholar
Long-term Risk of Venous Thromboembolism in Survivors of Childhood Cancer: A Report from the Childhood Cancer Survivor Study
Arin L. Madenci, Brent R. Weil, Qi Liu, A. Murphy +10 more
2018Journal of Clinical Oncology10 citations Open access
Semantic Scholar
A pilot induction regimen incorporating dinutuximab and sargramostim for the treatment of newly diagnosed high-risk neuroblastoma: A report from the Children's Oncology Group.
Sara M. Federico, A. Naranjo, Fan F. Zhang, A. Marachelian +16 more
2022Journal of Clinical Oncology8 citations
Semantic Scholar
Revised clinical and molecular risk strata define the incidence and pattern of failure in Medulloblastoma following risk-adapted radiotherapy and dose-intensive chemotherapy: results from a phase III multi-institutional study.
J. Lucas, C. Tinkle, Jie Huang, A. Onar-Thomas +13 more
2021Neuro-Oncology8 citations Open access
Semantic Scholar
Radiation dose response of neurologic symptoms during conformal radiotherapy for diffuse intrinsic pontine glioma
C. Tinkle, K. Campbell, Yuan-yuan Han, Yi-Mei Li +4 more
2020Journal of Neuro-Oncology8 citations Open access
Semantic Scholar
CTNI-27. FIRST-IN-PEDIATRICS PHASE I STUDY OF GDC-0084 (PAXALISIB), A CNS-PENETRANT PI3K/mTOR INHIBITOR, IN NEWLY DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) OR OTHER DIFFUSE MIDLINE GLIOMA (DMG)
C. Tinkle, Jie Huang, O. Campagne, H. Pan +13 more
20208 citations Open access
Semantic Scholar
Clinical implementation of magnetic resonance imaging systems for simulation and planning of pediatric radiation therapy
C. Hua, J. Uh, M. Krasin, John T. Jr Lucas +5 more
2018Journal of Medical Imaging and Radiation Sciences8 citations Open access
Semantic Scholar
Convergent evolution and multi-wave clonal invasion in H3 K27-altered diffuse midline gliomas treated with a PDGFR inhibitor
Sasi Arunachalam, K. Szlachta, Samuel W. Brady, Xiao-Tu Ma +12 more
2022Acta Neuropathologica Communications7 citations Open access
Semantic Scholar
Multi-institutional Analysis of Treatment Modalities in Basal Ganglia and Thalamic Germinoma
R. Graham, M. Abu-Arja, J. Stanek, A. Cappellano +26 more
2021Pediatric Blood & Cancer7 citations Open access
Semantic Scholar
Correlation between Multiparametric MR Imaging and Molecular Genetics in Pontine Pediatric High-Grade Glioma
V. Rameh, S. Vajapeyam, A. Ziaei, P. Kao +7 more
2023American Journal of Neuroradiology5 citations Open access
Semantic Scholar
NTRK Fusions Can Co-Occur With H3K27M Mutations and May Define Druggable Subclones Within Diffuse Midline Gliomas.
N. Dahl, A. Donson, Bridget Sanford, Dong Wang +8 more
2021Journal of Neuropathology and Experimental Neurology5 citations Open access
Semantic Scholar
Three discipline collaborative radiation therapy (3DCRT) special debate: The United States needs at least one carbon ion facility
E. Blakely, B. Faddegon, C. Tinkle, Charles Bloch +4 more
2019Journal of Applied Clinical Medical Physics5 citations Open access
Semantic Scholar
Convergent evolution and multi-wave clonal invasion in H3 K27-altered diffuse midline gliomas treated with a PDGFR inhibitor
Sasi Arunachalam, K. Szlachta, Samuel W. Brady, Xiao-Tu Ma +12 more
2022Acta Neuropathologica Communications3 citations Open access
Semantic Scholar
Treatment patterns and disease outcomes for pediatric patients with refractory or recurrent Hodgkin lymphoma treated with curative-intent salvage radiotherapy
C. Tinkle, N. Williams, Hui-Yun Wu, Jian-Rong Wu +7 more
2019Radiotherapy and Oncology3 citations Open access
Semantic Scholar
MODL-06. Targeting c-MET in combination with radiation is effective in MET-fusion driven high-grade glioma
Marc Zuckermann, Chen He, Jared M. Andrews, Roketa Sloan-Henry +24 more
2022Neuro-Oncology2 citations Open access
Semantic Scholar
Model‐based evaluation of image‐guided fractionated whole‐brain radiation therapy in pediatric diffuse intrinsic pontine glioma xenografts
Hillary R. Husband, O. Campagne, Chen He, Xiao-Yan Zhu +5 more
2021CPT: Pharmacometrics & Systems Pharmacology2 citations Open access
Semantic Scholar
Abstract 6144: St. Jude Pediatric Brain Tumor Portal: Cloud-based resource for patient-derived orthotopic xenograft (PDOX) models of pediatric high-grade glioma, ependymoma, and CNS embryonal tumors
P. Dunphy, Ke Xu, Darrell Gentry, Chen He +42 more
2020Tumor Biology2 citations
Semantic Scholar
HGG-35. COMBINATIONS OF QUANTITATIVE AND QUALITATIVE MRI FEATURES IDENTIFY PROGNOSTIC AND MOLECULAR SUBGROUPS OF SUPRATENTORIAL PEDIATRIC HIGH-GRADE GLIOMA
John T. Jr Lucas, Chih-Yang Hsu, Zhaohua Lu, J. Becksfort +7 more
2018Neuro-Oncology2 citations Open access
Semantic Scholar
Outcomes for young children with molecularly defined ependymoma treated on the multi-institutional SJYC07 clinical trial.
S. Upadhyaya, G. Robinson, Brent A. Orr, A. Onar-Thomas +16 more
20182 citations
Semantic Scholar
Conventionally Fractionated Re-irradiation for Recurrent Ependymoma.
Thomas E. Merchant, Hannah M. Worrall, Sheng-Jie Wu, Yi-Mei Li +16 more
2026Neuro-Oncology1 citations
Semantic Scholar
MEDB-42. GermlineElp1 deficiency promotes genomic instability and survival of granule neuron progenitors primed for SHH medulloblastoma pathogenesis
Jesus Garcia-Lopez, S. Ahmad, Yi-Ran Li, B. Gudenas +18 more
2022Neuro-Oncology1 citations Open access
Semantic Scholar
Population Pharmacokinetics of Crenolanib in Children and Young Adults with Brain Tumors
Cora Bisbee, O. Campagne, A. Gajjar, C. Tinkle +1 more
2022Cancer Chemotherapy and Pharmacology1 citations Open access
Semantic Scholar

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