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L. Mahakian · SciRah

Researcher profile · Semantic Scholar

L. Mahakian

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L. Mahakian — researcher profile on SciRah

h-index: 33
Works: 64
Citations: 2,701

Most-cited papers

Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis
Guodong Zhang, D. Panigrahy, L. Mahakian, Jun Yang +12 more
2013Proceedings of the National Academy of Sciences of the United States of America296 citations Open access
Semantic Scholar
Ultrasound localization microscopy to image and assess microvasculature in a rat kidney
J. Foiret, Hua Zhang, T. Ilovitsh, L. Mahakian +2 more
2017Scientific Reports150 citations Open access
Semantic Scholar
Specific penetration and accumulation of a homing peptide within atherosclerotic plaques of apolipoprotein E-deficient mice
J. Hamzah, V. R. Kotamraju, J. Seo, L. Agemy +7 more
2011Proceedings of the National Academy of Sciences of the United States of America124 citations Open access
Semantic Scholar
Priming is key to effective incorporation of image-guided thermal ablation into immunotherapy protocols.
Matthew T. Silvestrini, Elizabeth S. Ingham, L. Mahakian, A. Kheirolomoom +11 more
2017JCI Insight114 citations Open access
Semantic Scholar
Copper-doxorubicin as a nanoparticle cargo retains efficacy with minimal toxicity
A. Kheirolomoom, L. Mahakian, Chun-Yen Lai, H. Lindfors +10 more
2010Molecular Pharmaceutics110 citations Open access
Semantic Scholar
Ultrasound increases nanoparticle delivery by reducing intratumoral pressure and increasing transport in epithelial and epithelial-mesenchymal transition tumors
K. D. Watson, Chun-Yen Lai, Sheng-Ping Qin, D. Kruse +9 more
2012Cancer Research97 citations Open access
Semantic Scholar
Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis
Guodong Zhang, D. Panigrahy, S. Hwang, Jun Yang +10 more
2014Proceedings of the National Academy of Sciences of the United States of America94 citations Open access
Semantic Scholar
Long-Circulating 15 nm Micelles Based on Amphiphilic 3-Helix Peptide-PEG Conjugates
He Dong, N. Dube, Jessica Y. Shu, J. Seo +3 more
2012ACS Nano93 citations Open access
Semantic Scholar
Complete regression of local cancer using temperature-sensitive liposomes combined with ultrasound-mediated hyperthermia
A. Kheirolomoom, Chun-Yen Lai, Sarah M. Tam, L. Mahakian +3 more
2013Journal of Controlled Release90 citations Open access
Semantic Scholar
64Cu-Labeled LyP-1-Dendrimer for PET-CT Imaging of Atherosclerotic Plaque
J. Seo, Hyounggee Baek, L. Mahakian, Jiro Kusunose +3 more
2014Bioconjugate chemistry89 citations Open access
Semantic Scholar
Immune modulation resulting from MR-guided high intensity focused ultrasound in a model of murine breast cancer
B. Fite, James Z. Wang, Aris J. Kare, Asaf Ilovitsh +15 more
2021Scientific Reports87 citations Open access
Semantic Scholar
Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation
Michael Chavez, Matthew T. Silvestrini, Elizabeth S. Ingham, B. Fite +10 more
2018Theranostics78 citations Open access
Semantic Scholar
Enhanced microbubble contrast agent oscillation following 250 kHz insonation
T. Ilovitsh, Asaf Ilovitsh, J. Foiret, C. Caskey +8 more
2018Scientific Reports75 citations Open access
Semantic Scholar
CD8+ T-cell density imaging with 64Cu-labeled cys-diabody informs immunotherapy protocols
J. Seo, Richard Tavaré, L. Mahakian, Matthew T. Silvestrini +6 more
2018Clinical Cancer Research72 citations Open access
Semantic Scholar
Insonation of Targeted Microbubbles Produces Regions of Reduced Blood Flow within Tumor Vasculature
Xiaowen Hu, A. Kheirolomoom, L. Mahakian, Julie R. Beegle +3 more
2012Investigative Radiology68 citations Open access
Semantic Scholar
Development of thermosensitive resiquimod-loaded liposomes for enhanced cancer immunotherapy
Hua Zhang, Wei Tang, Azadeh Kheirolomoom, B. Fite +12 more
2020Journal of Controlled Release61 citations Open access
Semantic Scholar
Tumor-specific delivery of gemcitabine with activatable liposomes
Samantha T. Tucci, A. Kheirolomoom, Elizabeth S. Ingham, L. Mahakian +7 more
2019Journal of Controlled Release61 citations Open access
Semantic Scholar
Self-assembled 20-nm 64Cu-micelles enhance accumulation in rat glioblastoma
J. Seo, J. Ang, L. Mahakian, Sarah M. Tam +7 more
2015Journal of Controlled Release59 citations Open access
Semantic Scholar
Ultrasound Molecular Imaging of Tumor Angiogenesis with a Neuropilin-1-Targeted Microbubble
Hua Zhang, Sarah M. Tam, Elizabeth S. Ingham, L. Mahakian +6 more
2015Biomaterials58 citations Open access
Semantic Scholar
Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis
T. Sundstrøm, L. Prestegarden, F. Azuaje, Synnøve Nymark Aasen +18 more
2019Acta Neuropathologica Communications48 citations Open access
Semantic Scholar
Multimodal imaging enables early detection and characterization of changes in tumor permeability of brain metastases
F. Thorsen, B. Fite, L. Mahakian, J. Seo +10 more
2013Journal of Controlled Release48 citations Open access
Semantic Scholar
Liposomal Cu-64 labeling method using bifunctional chelators: polyethylene glycol spacer and chelator effects
J. Seo, L. Mahakian, A. Kheirolomoom, Hua Zhang +4 more
2010Bioconjugate chemistry48 citations Open access
Semantic Scholar
Magnetic Resonance Thermometry at 7T for Real-Time Monitoring and Correction of Ultrasound Induced Mild Hyperthermia
B. Fite, Yu Liu, D. Kruse, C. Caskey +6 more
2012PLoS ONE45 citations Open access
Semantic Scholar
Positron emission tomography imaging of novel AAV capsids maps rapid brain accumulation
J. Seo, Elizabeth S. Ingham, L. Mahakian, Spencer K. Tumbale +18 more
2020Nature Communications42 citations Open access
Semantic Scholar
In Vitro Characterization and In Vivo Ultrasound Molecular Imaging of Nucleolin-Targeted Microbubbles
Hua Zhang, Elizabeth S. Ingham, M. Gagnon, L. Mahakian +4 more
2016Biomaterials40 citations Open access
Semantic Scholar
Positron emission tomography imaging of the stability of Cu-64 labeled dipalmitoyl and distearoyl lipids in liposomes
J. Seo, Sheng-Ping Qin, L. Mahakian, K. D. Watson +2 more
2011Journal of Controlled Release40 citations Open access
Semantic Scholar
The pharmacokinetics of Zr-89 labeled liposomes over extended periods in a murine tumor model
J. Seo, L. Mahakian, Sarah M. Tam, Sheng-Ping Qin +3 more
2014Nuclear Medicine and Biology36 citations Open access
Semantic Scholar
Longitudinal investigation of permeability and distribution of macromolecules in mouse malignant transformation using PET
C. B. Rygh, Sheng-Ping Qin, J. Seo, L. Mahakian +8 more
2010Clinical Cancer Research36 citations Open access
Semantic Scholar
Toward Personalized Peptide-Based Cancer Nanovaccines: A Facile and Versatile Synthetic Approach
Hamilton Kakwere, Elizabeth S. Ingham, Riley P Allen, L. Mahakian +5 more
2017Bioconjugate chemistry35 citations Open access
Semantic Scholar
Combining activatable nanodelivery with immunotherapy in a murine breast cancer model
A. Kheirolomoom, Matthew T. Silvestrini, Elizabeth S. Ingham, L. Mahakian +6 more
2019Journal of Controlled Release34 citations Open access
Semantic Scholar
Comparison of PET Imaging with 64Cu-Liposomes and 18F-FDG in the 7,12-Dimethylbenz[a]anthracene (DMBA)-Induced Hamster Buccal Pouch Model of Oral Dysplasia and Squamous Cell Carcinoma
L. Mahakian, D. G. Farwell, Hua Zhang, J. Seo +6 more
2014Molecular Imaging and Biology34 citations Open access
Semantic Scholar
Effect of Alkyl Length of Peptide–Polymer Amphiphile on Cargo Encapsulation Stability and Pharmacokinetics of 3-Helix Micelles
N. Dube, J. Seo, He Dong, Jessica Y. Shu +4 more
2014Biomacromolecules34 citations Open access
Semantic Scholar
Immune‐mediated ECM depletion improves tumour perfusion and payload delivery
Y. Yeow, Venkata Ramana Kotamraju, Xiao Wang, M. Chopra +27 more
2019EMBO Molecular Medicine33 citations Open access
Semantic Scholar
Accumulation, internalization and therapeutic efficacy of neuropilin-1-targeted liposomes
E. E. Paoli, Elizabeth S. Ingham, Hua Zhang, L. Mahakian +6 more
2014Journal of Controlled Release33 citations Open access
Semantic Scholar
A comparison of image contrast with (64)Cu-labeled long circulating liposomes and (18)F-FDG in a murine model of mammary carcinoma.
Andrew W. Wong, E. Ormsby, Hua Zhang, J. Seo +3 more
2013American Journal of Nuclear Medicine and Molecular Imaging30 citations
Semantic Scholar
CpG expedites regression of local and systemic tumors when combined with activatable nanodelivery
A. Kheirolomoom, Elizabeth S. Ingham, L. Mahakian, Sarah M. Tam +7 more
2015Journal of Controlled Release28 citations Open access
Semantic Scholar
The cargo of CRPPR-conjugated liposomes crosses the intact murine cardiac endothelium
Hua Zhang, Ning Li, Padmini Sirish, L. Mahakian +5 more
2012Journal of Controlled Release28 citations Open access
Semantic Scholar
Ultrasound ablation enhances drug accumulation and survival in mammary carcinoma models.
Andrew W. Wong, B. Fite, Yu Liu, A. Kheirolomoom +8 more
2016Journal of Clinical Investigation27 citations Open access
Semantic Scholar
Magnetic Resonance Imaging Assessment of Effective Ablated Volume following High Intensity Focused Ultrasound
B. Fite, Andrew W. Wong, Yu Liu, L. Mahakian +7 more
2015PLoS ONE20 citations Open access
Semantic Scholar
Concurrent Visualization of Acoustic Radiation Force Displacement and Shear Wave Propagation with 7T MRI
Yu Liu, B. Fite, L. Mahakian, Sarah Johnson +3 more
2015PLoS ONE17 citations Open access
Semantic Scholar
In vivo validation and 3D visualization of broadband ultrasound molecular imaging.
Xiaowen Hu, C. Caskey, L. Mahakian, D. Kruse +6 more
2013American Journal of Nuclear Medicine and Molecular Imaging17 citations
Semantic Scholar
An Open Environment CT-US Fusion for Tissue Segmentation during Interventional Guidance
C. Caskey, M. Hlawitschka, Sheng-Ping Qin, L. Mahakian +3 more
2011PLoS ONE14 citations Open access
Semantic Scholar
Dynamic Contrast Enhanced MRI Detects Changes in Vascular Transport Rate Constants Following Treatment with Thermally-Sensitive Liposomal Doxorubicin
B. Fite, A. Kheirolomoom, J. Foiret, J. Seo +6 more
2017Journal of Controlled Release13 citations Open access
Semantic Scholar
5th International Symposium on Focused Ultrasound
M. Zaaroor, A. Sinai, D. Goldsher, A. Eran +496 more
2016Journal of Therapeutic Ultrasound13 citations Open access
Semantic Scholar
A Scalable Method for Squalenoylation and Assembly of Multifunctional 64Cu-Labeled Squalenoylated Gemcitabine Nanoparticles
Samantha T. Tucci, J. Seo, Hamilton Kakwere, A. Kheirolomoom +7 more
2018Nanotheranostics9 citations Open access
Semantic Scholar
Unimicellar hyperstars as multi-antigen cancer nanovaccines displaying clustered epitopes of immunostimulating peptides
Hamilton Kakwere, Elizabeth S. Ingham, Riley P Allen, L. Mahakian +5 more
2018Biomaterials Science6 citations Open access
Semantic Scholar
Super-localization of contrast agents in moving organs, first experiments in a rat kidney
J. Foiret, Hua Zhang, L. Mahakian, Sarah M. Tam +1 more
2016IUS6 citations
Semantic Scholar
Blood-brain barrier disruption for the delivery of non-infectious viral vectors and proteins, preliminary study
J. Foiret, Hua Zhang, B. Fite, T. Ilovitsh +6 more
2017IUS5 citations
Semantic Scholar
MR-guided focused ultrasound with spatial and temporal temperature control for hyperthermia
Yu Liu, Brett Z. Fite, D. Kruse, L. Mahakian +3 more
20112011 IEEE International Ultrasonics Symposium2 citations
Semantic Scholar
Longitudinal investigation of permeability and distribution of macromolecules in mouse tumor development and malignant transformation using PET
C. B. Rygh, J. Seo, S. Qin, L. Mahakian +6 more
20102 citations
Semantic Scholar

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