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P. Clemens · SciRah

Researcher profile · Semantic Scholar

P. Clemens

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P. Clemens — researcher profile on SciRah

h-index: 42
Works: 138
Citations: 11K

Most-cited papers

Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and pharmacological and psychosocial management.
K. Bushby, R. Finkel, D. Birnkrant, L. Case +10 more
2010Lancet Neurology1,934 citations Open access
Semantic Scholar
Diagnosis and management of Duchenne muscular dystrophy, part 2: implementation of multidisciplinary care.
K. Bushby, R. Finkel, D. Birnkrant, L. Case +10 more
2010Lancet Neurology1,116 citations Open access
Semantic Scholar
Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and neuromuscular, rehabilitation, endocrine, and gastrointestinal and nutritional management
D. Birnkrant, K. Bushby, C. Bann, S. Apkon +11 more
2018Lancet Neurology1,069 citations Open access
Semantic Scholar
A randomized study of alglucosidase alfa in late-onset Pompe's disease.
A. T. van der Ploeg, P. Clemens, D. Corzo, D. Escolar +19 more
2010New England Journal of Medicine704 citations Open access
Semantic Scholar
NF-κB inhibition delays DNA damage-induced senescence and aging in mice.
J. Tilstra, A. Robinson, Jin Wang, Siobhán Q. Gregg +15 more
2012Journal of Clinical Investigation459 citations Open access
Semantic Scholar
THE COOPERATIVE INTERNATIONAL NEUROMUSCULAR RESEARCH GROUP DUCHENNE NATURAL HISTORY STUDY: GLUCOCORTICOID TREATMENT PRESERVES CLINICALLY MEANINGFUL FUNCTIONAL MILESTONES AND REDUCES RATE OF DISEASE PROGRESSION AS MEASURED BY MANUAL MUSCLE TESTING AND OTHER COMMONLY USED CLINICAL TRIAL OUTCOME MEASUR
E. Henricson, R. Abresch, A. Cnaan, F. Hu +8 more
2013Muscle and Nerve202 citations Open access
Semantic Scholar
Current status of pharmaceutical and genetic therapeutic approaches to treat DMD.
Christophe Pichavant, Annemieke Aartsma-Rus, P. Clemens, K. Davies +7 more
2011Molecular Therapy202 citations Open access
Semantic Scholar
Safety, Tolerability, and Efficacy of Viltolarsen in Boys With Duchenne Muscular Dystrophy Amenable to Exon 53 Skipping
P. Clemens, V. Rao, A. Connolly, A. Harper +9 more
2020JAMA Neurology197 citations Open access
Semantic Scholar
THE COOPERATIVE INTERNATIONAL NEUROMUSCULAR RESEARCH GROUP DUCHENNE NATURAL HISTORY STUDY—A LONGITUDINAL INVESTIGATION IN THE ERA OF GLUCOCORTICOID THERAPY: DESIGN OF PROTOCOL AND THE METHODS USED
C. McDonald, E. Henricson, R. Abresch, Jay J. Han +7 more
2013Muscle and Nerve176 citations Open access
Semantic Scholar
Randomized, blinded trial of weekend vs daily prednisone in Duchenne muscular dystrophy
D. Escolar, Lauren P. Hache, P. Clemens, A. Cnaan +17 more
2011Neurology159 citations Open access
Semantic Scholar
Safety and efficacy of avalglucosidase alfa versus alglucosidase alfa in patients with late-onset Pompe disease (COMET): a phase 3, randomised, multicentre trial.
J. Diaz-Manera, P. Kishnani, H. Kushlaf, Shafeeq Ladha +25 more
2021Lancet Neurology133 citations Open access
Semantic Scholar
Open-label extension study following the Late-Onset Treatment Study (LOTS) of alglucosidase alfa.
A. T. van der Ploeg, R. Barohn, Lisa Carlson, J. Charrow +11 more
2012Molecular Genetics and Metabolism125 citations
Semantic Scholar
Species-specific immune responses generated by histidyl-tRNA synthetase immunization are associated with muscle and lung inflammation.
Y. Katsumata, W. Ridgway, T. Oriss, X. Gu +9 more
2007Journal of Autoimmunity113 citations Open access
Semantic Scholar
Efficacy and Safety of Vamorolone vs Placebo and Prednisone Among Boys With Duchenne Muscular Dystrophy
M. Guglieri, P. Clemens, Seth J. Perlman, E. Smith +42 more
2022JAMA Neurology111 citations Open access
Semantic Scholar
Phase IIa trial in Duchenne muscular dystrophy shows vamorolone is a first-in-class dissociative steroidal anti-inflammatory drug
L. Conklin, Jesse M. Damsker, E. Hoffman, W. Jusko +28 more
2018Pharmacological Research93 citations Open access
Semantic Scholar
Vamorolone trial in Duchenne muscular dystrophy shows dose-related improvement of muscle function
E. Hoffman, B. Schwartz, L. Mengle-Gaw, E. Smith +26 more
2019Neurology91 citations Open access
Semantic Scholar
Characteristics of late-onset myasthenia gravis
S. Živković, P. Clemens, D. Lacomis
2012Journal of Neurology72 citations
Semantic Scholar
Rapamycin Ameliorates Dystrophic Phenotype in mdx Mouse Skeletal Muscle
Saman Eghtesad, S. Jhunjhunwala, S. Little, P. Clemens
2011Molecular Medicine72 citations Open access
Semantic Scholar
Efficacy and safety of vamorolone in Duchenne muscular dystrophy: An 18-month interim analysis of a non-randomized open-label extension study
E. Smith, L. Conklin, E. Hoffman, P. Clemens +22 more
2020PLoS Medicine65 citations Open access
Semantic Scholar
Role of Innate Immunity in a Model of Histidyl-tRNA Synthetase (Jo-1)-mediated Myositis
M. Soejima, E. Kang, X. Gu, Y. Katsumata +2 more
2011Arthritis & Rheumatism65 citations Open access
Semantic Scholar
Peptide-Based Inhibition of NF-κB Rescues Diaphragm Muscle Contractile Dysfunction in a Murine Model of Duchenne Muscular Dystrophy
J. M. Peterson, William Kline, Benjamin D. Canan, Daniel J. Ricca +14 more
2011Molecular Medicine61 citations Open access
Semantic Scholar
Disease-specific and glucocorticoid-responsive serum biomarkers for Duchenne Muscular Dystrophy
Y. Hathout, Chen Liang, M. Ogundele, Ganggang Xu +10 more
2019Scientific Reports57 citations Open access
Semantic Scholar
High frequency of gastrointestinal manifestations in myotonic dystrophy type 1 and type 2
J. Hilbert, R. Barohn, P. Clemens, Elizabeth Luebbe +6 more
2017Neurology57 citations Open access
Semantic Scholar
Inhibition of the IKK/NF-κB Pathway by AAV Gene Transfer Improves Muscle Regeneration in Older mdx Mice
Ying Tang, D. Reay, Melessa Salay, Michael Y. Mi +5 more
2010Gene Therapy54 citations Open access
Semantic Scholar
Feasibility and Reproducibility of Echocardiographic Measures in Children with Muscular Dystrophies
C. Spurney, F. McCaffrey, A. Cnaan, L. Morgenroth +8 more
2015Journal of the American Society of Echocardiography53 citations Open access
Semantic Scholar
Serum pharmacodynamic biomarkers for chronic corticosteroid treatment of children
Y. Hathout, L. Conklin, Haeri Seol, H. Gordish-Dressman +11 more
2016Scientific Reports52 citations Open access
Semantic Scholar
Protein transduction: identification, characterization and optimization.
J. Tilstra, Khaja K. Rehman, Teresa R. Hennon, S. Plevy +2 more
2007Biochemical Society Transactions46 citations
Semantic Scholar
Systemic delivery of NEMO binding domain/IKKγ inhibitory peptide to young mdx mice improves dystrophic skeletal muscle histopathology
D. Reay, Michele L. Yang, J. Watchko, M. Daood +5 more
2011Neurobiology of Disease44 citations Open access
Semantic Scholar
Insights into bone health in Duchenne muscular dystrophy.
V. Morgenroth, Lauren P. Hache, P. Clemens
2012BoneKEy Reports43 citations Open access
Semantic Scholar
Efficacy and Safety of Avalglucosidase Alfa in Patients With Late-Onset Pompe Disease After 97 Weeks
P. Kishnani, J. Diaz-Manera, A. Toscano, P. Clemens +23 more
2023JAMA Neurology41 citations Open access
Semantic Scholar
Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation
Jing Zhao, Lei Zhang, Xiaodong Mu, Christelle Doebelin +14 more
2018PLoS Biology40 citations Open access
Semantic Scholar
Long-Term Functional Efficacy and Safety of Viltolarsen in Patients with Duchenne Muscular Dystrophy
P. Clemens, V. Rao, A. Connolly, A. Harper +6 more
2022Journal of Neuromuscular Diseases38 citations Open access
Semantic Scholar
Novel mutation in MYH7 gene associated with distal myopathy and cardiomyopathy.
H. Homayoun, S. Khavandgar, J. Hoover, A. Mohsen +3 more
2011Neuromuscular Disorders38 citations
Semantic Scholar
Discovery of Metabolic Biomarkers for Duchenne Muscular Dystrophy within a Natural History Study
S. Boca, M. Nishida, Michael Harris, Shruti Rao +11 more
2016PLoS ONE37 citations Open access
Semantic Scholar
Bone Health and Associated Metabolic Complications in Neuromuscular Diseases
N. Joyce, Lauren P. Hache, P. Clemens
2012Physical Medicine and Rehabilitation Clinics of North America36 citations Open access
Semantic Scholar
Improvement of the mdx mouse dystrophic phenotype by systemic in utero AAV8 delivery of a minidystrophin gene
Bhanu Munil Koppanati, Juan Li, D. Reay, Bing Wang +5 more
2010Gene Therapy36 citations Open access
Semantic Scholar
Serum biomarkers associated with baseline clinical severity in young steroid-naïve Duchenne muscular dystrophy boys
Utkarsh J. Dang, Michał Ziemba, P. Clemens, Y. Hathout +2 more
2020Human Molecular Genetics33 citations Open access
Semantic Scholar
Functional Redundancy of MyD88-dependent Signaling Pathways in a Murine Model of Histidyl-tRNA Synthetase-induced Myositis
I. Fernández, L. Harlow, Y. Zang, R. Liu-Bryan +3 more
2013Journal of Immunology31 citations Open access
Semantic Scholar
A Transition Toolkit for Duchenne Muscular Dystrophy
Christina J. Trout, L. Case, P. Clemens, A. McArthur +5 more
2018Pediatrics29 citations Open access
Semantic Scholar
Efficacy and Safety of Viltolarsen in Boys With Duchenne Muscular Dystrophy: Results From the Phase 2, Open-Label, 4-Year Extension Study
P. Clemens, V. Rao, A. Connolly, A. Harper +6 more
2023Journal of Neuromuscular Diseases28 citations Open access
Semantic Scholar
Pharmacological therapies for muscular dystrophies.
H. Abdel-Hamid, P. Clemens
2012Current Opinion in Neurology28 citations
Semantic Scholar
Multi-Omics Identifies Circulating miRNA and Protein Biomarkers for Facioscapulohumeral Dystrophy
Christoph Heier, Ai-Ping Zhang, Nhu Y Nguyen, Christopher B. Tully +17 more
2020Journal of Personalized Medicine24 citations Open access
Semantic Scholar
Neurodevelopmental Needs in Young Boys with Duchenne Muscular Dystrophy (DMD): Observations from the Cooperative International Neuromuscular Research Group (CINRG) DMD Natural History Study (DNHS).
M. Thangarajh, C. Spurney, H. Gordish-Dressman, P. Clemens +4 more
2018PLOS Currents24 citations Open access
Semantic Scholar
Pentoxifylline as a rescue treatment for DMD
D. Escolar, A. Zimmerman, Tulio E. Bertorini, P. Clemens +18 more
2012Neurology24 citations Open access
Semantic Scholar
A multinational study on motor function in early-onset FSHD
J. Mah, Jia Feng, M. Jacobs, T. Duong +17 more
2018Neurology23 citations Open access
Semantic Scholar
The CINRG Becker Natural History Study: Baseline Characteristics
P. Clemens, G. Niizawa, Jia Feng, J. Florence +22 more
2020Muscle and Nerve18 citations Open access
Semantic Scholar
Modeling Early Heterogeneous Rates of Progression in Boys with Duchenne Muscular Dystrophy
Yuan-Zhong Fang, C. McDonald, P. Clemens, H. Gordish +3 more
2023Journal of Neuromuscular Diseases14 citations Open access
Semantic Scholar
Exposure-Response Analysis of Vamorolone (VBP15) in Boys with Duchenne Muscular Dystrophy
Xiao-Nan Li, L. Conklin, J. V. van den Anker, E. Hoffman +2 more
2020Journal of clinical pharmacology13 citations Open access
Semantic Scholar
Population Pharmacokinetics of Vamorolone (VBP15) in Healthy Men and Boys with Duchenne Muscular Dystrophy
Panteleimon D. Mavroudis, J. V. van den Anker, L. Conklin, Jesse M. Damsker +4 more
2019Journal of clinical pharmacology12 citations Open access
Semantic Scholar
Deubiquitinating enzyme A20 negatively regulates NF‐κB signaling in skeletal muscle in mdx mice
Rakshita A. Charan, Ryan L. Hanson, P. Clemens
2012The FASEB Journal12 citations
Semantic Scholar

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