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A. Hoffbrand · SciRah

Researcher profile · Semantic Scholar

A. Hoffbrand

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A. Hoffbrand — researcher profile on SciRah

h-index: 40
Works: 181
Citations: 6,300

Most-cited papers

Interferon gamma inhibits apoptotic cell death in B cell chronic lymphocytic leukemia
M. Buschle, D. Campana, S. Carding, C. Richard +2 more
1993Journal of Experimental Medicine265 citations Open access
Semantic Scholar
Philadelphia positive acute lymphoblastic leukemia in adults: age distribution, BCR breakpoint and prognostic significance.
L. Secker-Walker, J. Craig, J. Hawkins, A. Hoffbrand
1991Leukemia248 citations
Semantic Scholar
Minimal residual disease tests provide an independent predictor of clinical outcome in adult acute lymphoblastic leukemia.
F. Y. Mortuza, M. Papaioannou, I. Moreira, L. Coyle +6 more
2002Journal of Clinical Oncology201 citations
Semantic Scholar
1,2-Dimethyl-3-hydroxypyrid-4-one, an orally active chelator for treatment of iron overload.
G. Kontoghiorghes, L. Sheppard, M. Aldouri, A. Hoffbrand
1987The Lancet172 citations Open access
Semantic Scholar
Role of autoimmune gastritis, Helicobacter pylori and celiac disease in refractory or unexplained iron deficiency anemia.
C. Hershko, A. Hoffbrand, D. Keret, M. Souroujon +3 more
2005Haematologica171 citations
Semantic Scholar
The history of folic acid
A. Hoffbrand, D. Weir
2001British Journal of Haematology169 citations
Semantic Scholar
Ketoconazole versus nystatin plus amphotericin B for fungal prophylaxis in severely immunocompromised patients.
I. Hann, H. Prentice, R. Corringham, H. Blacklock +8 more
1982The Lancet144 citations
Semantic Scholar
Acyclovir prophylaxis against herpes virus infections in severely immunocompromised patients: randomised double blind trial.
Ian Hann, H. Prentice, H. Blacklock, M. Ross +6 more
1983British medical journal135 citations Open access
Semantic Scholar
Immune donors can protect marrow-transplant recipients from severe cytomegalovirus infections.
J. Grob, H. Prentice, A. Hoffbrand, T. Tate +5 more
1987The Lancet122 citations
Semantic Scholar
Stomatococcus mucilaginosus: an emerging pathogen in neutropenic patients.
P. Mcwhinney, C. Kibbler, Stephen H. Gillespie, S. Patel +3 more
1992Clinical Infectious Diseases77 citations
Semantic Scholar
Rearrangement of immunoglobulin and T cell antigen receptor genes in acute myeloid leukemia with lymphoid-associated markers.
J. Norton, D. Campana, A. Hoffbrand, G. Janossy +4 more
1987Leukemia69 citations
Semantic Scholar
The effect of vitamin B12 deficiency on methylfolate metabolism and pteroylpolyglutamate synthesis in human cells.
A. Lavoie, E. Tripp, A. Hoffbrand
1974Clinical science and molecular medicine67 citations
Semantic Scholar
Evidence for intestinal origin of transcobalamin II during vitamin B12 absorption.
I. Chanarin, M. Muir, A. Hughes, A. Hoffbrand
1978British medical journal58 citations Open access
Semantic Scholar
Homozygous protein C deficiency with delayed onset of symptoms at 7 to 10 months.
E. Tuddenham, T. Takase, Angela E. Thomas, As Awidi +4 more
1989Thrombosis Research55 citations
Semantic Scholar
Serum ferritin concentration in Gaucher's disease.
M. Morgan, A. Hoffbrand, M. Laulicht, W. Luck +1 more
1983British medical journal48 citations Open access
Semantic Scholar
Effect of Fasting
C. Billich, G. Bray, A. Hoffbrand, R. Levitan
201742 citations
Semantic Scholar
The contribution of large granular lymphocytes to B cell activation and differentiation after T-cell-depleted allogeneic bone marrow transplantation.
Malcolm K. Brenner, J. Reittie, J. Grob, J. Wimperis +4 more
1986Transplantation42 citations Open access
Semantic Scholar
Expression of the E2A-PBX1 fusion transcripts in t(1;19)(q23;p13) and der(19)t(1;19) at diagnosis and in remission of acute lymphoblastic leukemia with different B lineage immunophenotypes.
Prema E. Devaraj, L. Foroni, G. Janossy, A. Hoffbrand +1 more
1995Leukemia39 citations
Semantic Scholar
Streptococcus mitis and ARDS in neutropenic patients.
P. Mcwhinney, Stephen H. Gillespie, C. Kibbler, A. Hoffbrand +1 more
1991The Lancet39 citations
Semantic Scholar
Serum vitamin B12 and transcobalamin levels in early HIV disease
S. Rule, M. Hooker, C. Costello, W. Luck +1 more
1994American journal of hematology/oncology38 citations
Semantic Scholar
B cell development and regulation after T cell-depleted marrow transplantation.
J. Wimperis, Malcolm K. Brenner, H. Prentice, E. J. Thompson +1 more
1987Journal of Immunology38 citations
Semantic Scholar
V(H) gene usage differs in germline and mutated B-cell chronic lymphocytic leukemia.
V. Duke, D. Gandini, P. Sherrington, Ke Lin +5 more
2003Haematologica37 citations
Semantic Scholar
Genotypes and immunophenotypes of Hodgkin's disease-derived cell lines.
H. Drexler, B. Leber, J. Norton, J. Yaxley +3 more
1988Leukemia37 citations
Semantic Scholar
Minimal residual disease monitoring in adult T-cell acute lymphoblastic leukemia: a molecular based approach using T-cell receptor G and D gene rearrangements.
P. Gameiro, F. Y. Mortuza, A. Hoffbrand, L. Foroni
2002Haematologica36 citations
Semantic Scholar
Mixed acute leukaemias.
A. Hoffbrand, B. Leber, P. Browett, J. Norton
1988Blood reviews34 citations
Semantic Scholar
Variable kappa gene rearrangement in lymphoproliferative disorders: an analysis of V kappa gene usage, VJ joining and somatic mutation.
P. Cannell, P. Amlot, M. Attard, A. Hoffbrand +1 more
1994Leukemia33 citations
Semantic Scholar
Heavy metal intoxication from homeopathic and herbal remedies.
A. Olujohungbe, P. Fields, A. Sandford, A. Hoffbrand
1994Postgraduate medical journal31 citations Open access
Semantic Scholar
Synthesis of folate polyglutamates in human cells.
A. Hoffbrand, E. Tripp, A. Lavoie
1976Clinical science and molecular medicine30 citations
Semantic Scholar
Correlation of immunophenotype with rearrangement of T cell antigen receptor beta and gamma genes in acute lymphoblastic leukemia of adults.
J. Norton, D. Campana, A. Hoffbrand, G. Janossy +4 more
1988Leukemia26 citations
Semantic Scholar
Polyglutamate forms of folate in resting and proliferating mammalian tissues.
A. Lavoie, E. Tripp, K. Parsa, A. Hoffbrand
1975Clinical science and molecular medicine25 citations
Semantic Scholar
In vitro analysis of the interactions of recombinant IL-2 with regenerating lymphoid and myeloid cells after allogeneic marrow transplantation.
H. Heslop, G. Price, H. Prentice, F. Cordingley +3 more
1988Journal of Immunology24 citations Open access
Semantic Scholar
The PML-RAR alpha transcript in long-term follow-up of acute promyelocytic leukemia patients.
P. Gameiro, S. Vieira, P. Carrara, A. L. Silva +8 more
2001Haematologica22 citations
Semantic Scholar
Platelet monoamine oxidase activity in megaloblastic anaemia.
V. Glover, M. Sandler, A. Hughes, A. Hoffbrand
1980Journal of Clinical Pathology22 citations Open access
Semantic Scholar
Bone-marrow aspiration and trephine biopsy (1).
S. Knowles, A. Hoffbrand
1980British medical journal18 citations Open access
Semantic Scholar
Chromosome studies in megaloblastic anaemia before and after treatment.
S. D. Lawler, P. Roberts, A. Hoffbrand
2009Scandinavian Journal of Haematology16 citations
Semantic Scholar
IL-4 acts as a homeostatic regulator of IL-2-induced TNF and IFN-gamma.
C. Bello‐Fernandez, P. Obląkowski, A. Meager, A. Duncombe +3 more
1991Immunology16 citations
Semantic Scholar
Hereditary abnormal transcobalamin II previously diagnosed as congenital dihydrofolate reductase deficiency.
A. Hoffbrand, E. Tripp, B. Jackson, W. Luck +1 more
1984New England Journal of Medicine15 citations
Semantic Scholar
Effects of tumour necrosis factor and alpha interferon on chronic B cell malignancies.
A. Bianchi, Helen E. Heslop, H. Drexler, F. Cordingley +4 more
1988Nouvelle revue francaise d'hematologie13 citations
Semantic Scholar
Hereditary transcobalamin II deficiency: a 22 year follow up.
P. Thomas, A. Hoffbrand
1997Journal of Neurology Neurosurgery & Psychiatry12 citations Open access
Semantic Scholar
What does apoptosis mean in CLL?
J. Binet, W. Plunkett, B. Robertson, H. Merle-Béral +3 more
1996Leukemia and Lymphoma12 citations
Semantic Scholar
DIFFERENTIAL RECOVERY OF PHENOTYPICALLY AND FUNCTIONALLY DISTINCT CIRCULATING ANTIGEN‐PRESENTING CELLS AFTER ALLOGENEIC MARROW TRANSPLANTATION
J. Reittie, L. Poulter, H. Prentice, J. Burns +6 more
1988Transplantation12 citations Open access
Semantic Scholar
Infection with Yersinia enterocolitica in patients with iron overload.
H.-Y. Chiu, D. Flynn, A. Hoffbrand, D. Politis
1986British medical journal12 citations Open access
Semantic Scholar
Bilateral osteonecrosis of the head of the femur complicating acute promyelocytic leukemia: a sequel to treatment of retinoic acid syndrome with dexamethasone.
S. Albahar, R. Pandita, A. Hoffbrand
1996Acta Haematologica11 citations
Semantic Scholar
A randomized trial of empirical antibiotic therapy with one of four beta-lactam antibiotics in combination with netilmicin in febrile neutropenic patients.
R. Sage, Ian Hann, H. Prentice, Stephen Devereux +9 more
1988Journal of Antimicrobial Chemotherapy11 citations
Semantic Scholar
Long-term clearance of [57Co]cyanocobalamin in vegans and pernicious anaemia.
S. Amin, T. Spinks, A. Ranicar, M. D. Short +1 more
1980Clinical science11 citations
Semantic Scholar
T-cell receptor gene rearrangement in B-cell non-Hodgkin's lymphoma: correlation with methylation and expression.
B. Leber, P. Amlot, A. Hoffbrand, J. Norton
1989Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis10 citations
Semantic Scholar
A comparison of double beta-lactam combinations with netilmicin/ureidopenicillin regimens in the empirical therapy of febrile neutropenic patients.
C. C. Kibbler, H. Prentice, R. Sage, A. Hoffbrand +5 more
1989Journal of Antimicrobial Chemotherapy10 citations
Semantic Scholar
Transcobalamin II deficiency: long-term follow-up of two cases.
M. C. Arrabal, A. Villegas, E. Mariscal, B. Lentijo +2 more
1988Acta Haematologica10 citations
Semantic Scholar
Recovery of immunoglobulin isotypes following T-cell depleted allogeneic bone marrow transplantation.
M. Brenner, J. Wimperis, J. Reittie, J. Patterson +3 more
1986British Journal of Haematology10 citations
Semantic Scholar
Inter conversion of cobalamins in human lymphocytes in vitro and the influence of nitrous oxide on synthesis of cobalamin coenzymes
E. Quadros, Beverley Jackson, A. Hoffbrand, J. Linnell
197910 citations
Semantic Scholar

Frequent co-authors

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H. Prentice×16
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H. Prentice — researcher profile on SciRah
M. Brenner×5
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M. Brenner — researcher profile on SciRah
L. Foroni×5
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L. Foroni — researcher profile on SciRah
J. Norton×5
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J. Norton — researcher profile on SciRah

×4

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J. Wimperis — researcher profile on SciRah

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E. Tripp — researcher profile on SciRah

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W. Luck — researcher profile on SciRah

Malcolm K. Brenner×4

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Malcolm K. Brenner — researcher profile on SciRah

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D. Campana — researcher profile on SciRah

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P. Gameiro — researcher profile on SciRah

H. Blacklock×3

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H. Blacklock — researcher profile on SciRah

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G. Janossy — researcher profile on SciRah