F. Gai

Most-cited papers

Microscopic insights into the protein-stabilizing effect of trimethylamine N-oxide (TMAO)
Jianqiang Ma, I. Pazos, F. Gai
2014Proceedings of the National Academy of Sciences of the United States of America235 citations Open access
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Site-Specific Infrared Probes of Proteins
Jianqiang Ma, I. Pazos, Wenkai Zhang, R. Culik +1 more
2015Annual review of physical chemistry (Print)174 citations Open access
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Site-Specific Spectroscopic Reporters of the Local Electric Field, Hydration, Structure, and Dynamics of Biomolecules
M. Waegele, R. Culik, F. Gai
2011Journal of Physical Chemistry Letters159 citations Open access
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Divalent cation-induced cluster formation by polyphosphoinositides in model membranes
Yu-Hsiu Wang, Agnieszka Collins, Lin Guo, K. B. Smith-Dupont +3 more
2012Journal of the American Chemical Society126 citations Open access
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Blue fluorescent amino acid for biological spectroscopy and microscopy
M. Hilaire, Ismail A. Ahmed, Chun-Wei Lin, Hyunil Jo +2 more
2017Proceedings of the National Academy of Sciences of the United States of America109 citations Open access
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The Two Dimensional Vibrational Echo of a Nitrile Probe of the Villin HP35 Protein
Diana C. Urbanek, Dmitriy Yu. Vorobyev, Arnaldo L. Serrano, F. Gai +1 more
2010Journal of Physical Chemistry Letters90 citations Open access
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Spectroscopic studies of protein folding: Linear and nonlinear methods
Arnaldo L. Serrano, M. Waegele, F. Gai
2012Protein Science78 citations Open access
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Transmembrane orientation and possible role of the fusogenic peptide from parainfluenza virus 5 (PIV5) in promoting fusion
Jason E. Donald, Yao Zhang, G. Fiorin, V. Carnevale +4 more
2011Proceedings of the National Academy of Sciences of the United States of America76 citations Open access
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Ester Carbonyl Vibration as a Sensitive Probe of Protein Local Electric Field
I. Pazos, Ayanjeet Ghosh, M. J. Tucker, F. Gai
2014Angewandte Chemie74 citations Open access
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Achieving Secondary Structural Resolution in Kinetic Measurements of Protein Folding: A Case Study of the Folding Mechanism of Trp-cage
R. Culik, Arnaldo L. Serrano, Michelle R. Bunagan, F. Gai
2011Angewandte Chemie73 citations Open access
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Using Thioamides to Site-Specifically Interrogate the Dynamics of Hydrogen Bond Formation in β-Sheet Folding
R. Culik, Hyunil Jo, W. DeGrado, F. Gai
2012Journal of the American Chemical Society72 citations Open access
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A 31-residue peptide induces aggregation of tau’s microtubule-binding region in cells
Jan Stöhr, Haifan Wu, M. Nick, Yibing Wu +13 more
2017Nature Chemistry63 citations Open access
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Computational design of a β–peptide that targets transmembrane helices
Scott J. Shandler, I. Korendovych, David T. Moore, K. B. Smith-Dupont +6 more
2011Journal of the American Chemical Society57 citations Open access
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Experimental Validation of the Role of Trifluoroethanol as a Nanocrowder
R. Culik, Rachel M. Abaskharon, I. Pazos, F. Gai
2014Journal of Physical Chemistry B52 citations Open access
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Solvent Dependence of Cyanoindole Fluorescence Lifetime
M. Hilaire, Debopreeti Mukherjee, T. Troxler, F. Gai
2017Chemical Physics Letters50 citations Open access
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Selective Incorporation of Nitrile-Based Infrared Probes into Proteins via Cysteine Alkylation
Hyunil Jo, R. Culik, I. Korendovych, W. DeGrado +1 more
2010Biochemistry50 citations Open access
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Utility of 5-Cyanotryptophan Fluorescence as a Sensitive Probe of Protein Hydration
Beatrice N. Markiewicz, Debopreeti Mukherjee, T. Troxler, F. Gai
2016Journal of Physical Chemistry B49 citations Open access
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C≡N Stretching Vibration of 5-Cyanotryptophan as an Infrared Probe of Protein Local Environment: What Determines Its Frequency?
Wenkai Zhang, Beatrice N. Markiewicz, Rosalie S Doerksen, Amos B. Smith +1 more
2016Physical Chemistry, Chemical Physics - PCCP48 citations Open access
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2D IR Spectroscopy of Histidine: Probing Sidechain Structure and Dynamics via Backbone Amide I Vibration
Ayanjeet Ghosh, M. J. Tucker, F. Gai
2014Journal of Physical Chemistry B47 citations Open access
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A Solute's Perspective on How TMAO, Urea and GdnHCl Affect Water's Hydrogen Bonding Ability
I. Pazos, F. Gai
2012Journal of Physical Chemistry B43 citations Open access
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Kinetic Isotope Effect Provides Insight into the Vibrational Relaxation Mechanism of Aromatic Molecules: Application to Cyano-phenylalanine
J. Rodgers, Wenkai Zhang, C. Bazewicz, Jianxin Chen +2 more
2016Journal of Physical Chemistry Letters37 citations Open access
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Infrared Signature and Folding Dynamics of a Helical β-Peptide
Geronda L. Montalvo, M. Waegele, Scott J. Shandler, F. Gai +1 more
2010Journal of the American Chemical Society35 citations Open access
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Native State Conformational Heterogeneity of HP35 Revealed by Time-Resolved FRET
Arnaldo L. Serrano, O. Bilsel, F. Gai
2012Journal of Physical Chemistry B34 citations Open access
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Fermi Resonance as a Means to Determine the Hydrogen-Bonding Status of Two Infrared Probes
J. Rodgers, Rachel M. Abaskharon, Bei Ding, Jianxin Chen +2 more
2017Physical Chemistry, Chemical Physics - PCCP33 citations Open access
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Kinetics of Exchange Between Zero-, One-, and Two-Hydrogen-Bonded States of Methyl and Ethyl Acetate in Methanol
Lev Chuntonov, I. Pazos, Jianqiang Ma, F. Gai
2015Journal of Physical Chemistry B32 citations Open access
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Direct Assessment of the α-Helix Nucleation Time
Arnaldo L. Serrano, M. J. Tucker, F. Gai
2011Journal of Physical Chemistry B31 citations Open access
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2D IR spectroscopy reveals the role of water in the binding of channel-blocking drugs to the influenza M2 channel.
Ayanjeet Ghosh, Jun Wang, Yurii S. Moroz, I. Korendovych +4 more
2014Journal of Chemical Physics29 citations Open access
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Direct Measurement of the Tryptophan-Mediated Photocleavage Kinetics of a Protein Disulfide Bond
Rachel M. Abaskharon, F. Gai
2016Physical Chemistry, Chemical Physics - PCCP28 citations Open access
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Light-triggered Disassembly of Amyloid Fibrils
T. Measey, F. Gai
2012Langmuir28 citations Open access
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Photoenhancement of the C≡N Stretching Vibration Intensity of Aromatic Nitriles.
Jingsong Liu, Ran-ran Feng, Liang Zhou, F. Gai +1 more
2022Journal of Physical Chemistry Letters27 citations
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Biomolecular Crowding Arising from Small Molecules, Molecular Constraints, Surface Packing, and Nano-Confinement
M. Hilaire, Rachel M. Abaskharon, F. Gai
2015Journal of Physical Chemistry Letters27 citations Open access
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Power-law dependence of the melting temperature of ubiquitin on the volume fraction of macromolecular crowders.
M. Waegele, F. Gai
2011Journal of Chemical Physics27 citations Open access
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Design of a Short Thermally Stable α-Helix Embedded in a Macrocycle
Haifan Wu, Arusha Acharyya, Yibing Wu, Lijun Liu +3 more
2018ChemBioChem24 citations Open access
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Infrared and Fluorescence Assessment of Protein Dynamics: From Folding to Function
Bei Ding, M. Hilaire, F. Gai
2016Journal of Physical Chemistry B23 citations Open access
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Tryptophan as a Template for Development of Visible Fluorescent Amino Acids.
Arusha Acharyya, Wen-Kai Zhang, F. Gai
2021Journal of Physical Chemistry B22 citations
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Fluorescence Correlation Spectroscopy Measurements of the Membrane Protein TetA in Escherichia coli Suggest Rapid Diffusion at Short Length Scales
D. Chow, Lin Guo, F. Gai, M. Goulian
2012PLoS ONE22 citations Open access
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Using VIPT-Jump to Distinguish Between Different Folding Mechanisms: Application to BBL and a Trpzip
Chun-Wei Lin, R. Culik, F. Gai
2013Journal of the American Chemical Society21 citations Open access
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Synthesis and Characterization of the Fluorescence Utility of Two Visible-Light-Absorbing Tryptophan Derivatives
Robert J. Micikas, Arusha Acharyya, Amos B. Smith, F. Gai
2022Chemical Physics Letters20 citations
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Exposing the Nucleation Site in α-Helix Folding: A Joint Experimental and Simulation Study
Arusha Acharyya, Yun-Hui Ge, Haifan Wu, W. DeGrado +2 more
2019Journal of Physical Chemistry B20 citations Open access
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Do guanidinium and tetrapropylammonium ions specifically interact with aromatic amino acid side chains?
Bei Ding, Debopreeti Mukherjee, Jianxin Chen, F. Gai
2017Proceedings of the National Academy of Sciences of the United States of America19 citations Open access
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Photoinduced Electron Transfer and Fluorophore Motion as a Probe of the Conformational Dynamics of Membrane Proteins: Application to the Influenza A M2 Proton Channel
Julie M G Rogers, Alexei L. Polishchuk, Lin Guo, Jun Wang +2 more
2011Langmuir19 citations Open access
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Possible Existence of α-Sheets in the Amyloid Fibrils Formed by a TTR105–115 Mutant
M. Hilaire, Bei Ding, Debopreeti Mukherjee, Jianxin Chen +1 more
2018Journal of the American Chemical Society18 citations Open access
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Aggregation Gatekeeper and Controlled Assembly of Trpzip β-Hairpins
Beatrice N. Markiewicz, Rolando Oyola, De-Guo Du, F. Gai
2014Biochemistry18 citations Open access
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Heterogeneous diffusion of a membrane-bound pHLIP peptide.
Lin Guo, F. Gai
2010Biophysical Journal18 citations Open access
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Infrared and Fluorescence Assessment of the Hydration Status of the Tryptophan Gate in Influenza A M2 Proton Channel
Beatrice N. Markiewicz, T. Lemmin, Wenkai Zhang, Ismail A. Ahmed +5 more
2016Physical Chemistry, Chemical Physics - PCCP17 citations Open access
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Exciton CD Couplet Arising From Nitrile-Derivatized Aromatic Residues as a Structural Probe of Proteins
Debopreeti Mukherjee, F. Gai
2016Analytical Biochemistry17 citations Open access
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Quenching of p-Cyanophenylalanine Fluorescence by Various Anions
I. Pazos, R. Roesch, F. Gai
2013Chemical Physics Letters17 citations Open access
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Simple Method to Enhance the Photostability of the Fluorescence Reporter R6G for Prolonged Single Molecule Studies
Lin Guo, F. Gai
2013Journal of Physical Chemistry A17 citations Open access
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Diffusion as a Probe of the Heterogeneity of Antimicrobial Peptide-Membrane Interactions
K. B. Smith-Dupont, Lin Guo, F. Gai
2010Biochemistry17 citations Open access
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PET and FRET Utility of an Amino Acid Pair: Tryptophan and 4-Cyanotryptophan
Ismail A. Ahmed, J. Rodgers, C. Eng, T. Troxler +1 more
2019Physical Chemistry, Chemical Physics - PCCP16 citations Open access
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