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S. Kupzig · SciRah

Researcher profile · Semantic Scholar

S. Kupzig

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S. Kupzig — researcher profile on SciRah

h-index: 18
Works: 35
Citations: 1,773

Most-cited papers

Bst‐2/HM1.24 Is a Raft‐Associated Apical Membrane Protein with an Unusual Topology
S. Kupzig, V. Korolchuk, R. Rollason, A. Sugden +2 more
2003Traffic : the International Journal of Intracellular Transport457 citations Open access
Semantic Scholar
An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells
Kongtana Trakarnsanga, R. Griffiths, Marieangela C. Wilson, Allison Blair +9 more
2017Nature Communications193 citations Open access
Semantic Scholar
Maturing reticulocytes internalize plasma membrane in glycophorin A-containing vesicles that fuse with autophagosomes before exocytosis.
R. Griffiths, S. Kupzig, Nicola M. Cogan, T. Mankelow +6 more
2012Blood180 citations Open access
Semantic Scholar
Epigenetic silencing of a Ca2+-regulated Ras GTPase-activating protein RASAL defines a new mechanism of Ras activation in human cancers
Hong-Chuan Jin, Xian Wang, J. Ying, A. Wong +10 more
2007Proceedings of the National Academy of Sciences of the United States of America133 citations Open access
Semantic Scholar
The frequencies of calcium oscillations are optimized for efficient calcium-mediated activation of Ras and the ERK/MAPK cascade.
S. Kupzig, S. Walker, P. Cullen
2005Proceedings of the National Academy of Sciences of the United States of America126 citations Open access
Semantic Scholar
GAP1 Family Members Constitute Bifunctional Ras and Rap GTPase-activating Proteins
S. Kupzig, Delia Deaconescu, D. Bouyoucef, S. Walker +7 more
2006Journal of Biological Chemistry91 citations Open access
Semantic Scholar
Identification of a Ras GTPase‐activating protein regulated by receptor‐mediated Ca2+ oscillations
S. Walker, S. Kupzig, D. Bouyoucef, L. C. Davies +9 more
2004EMBO Journal89 citations Open access
Semantic Scholar
GAP1IP4BP contains a novel group I pleckstrin homology domain that directs constitutive plasma membrane association.
G. Cozier, P. J. Lockyer, J. S. Reynolds, S. Kupzig +4 more
2000Journal of Biological Chemistry83 citations Open access
Semantic Scholar
Identification of the ras GTPase-activating protein GAP1(m) as a phosphatidylinositol-3,4,5-trisphosphate-binding protein in vivo.
P. J. Lockyer, Stefan Wennström, S. Kupzig, K. Venkateswarlu +2 more
1999Current Biology76 citations Open access
Semantic Scholar
Protein Distribution during Human Erythroblast Enucleation In Vitro
Amanda J. Bell, T. Satchwell, K. Heesom, Bethan R. Hawley +5 more
2013PLoS ONE52 citations Open access
Semantic Scholar
The GAP1 family of GTPase-activating proteins: spatial and temporal regulators of small GTPase signalling.
Sam Yarwood, Dalila Bouyoucef-Cherchalli, P. Cullen, S. Kupzig
2006Biochemical Society Transactions50 citations
Semantic Scholar
The ins and outs of human reticulocyte maturation
R. Griffiths, S. Kupzig, Nicola M. Cogan, T. Mankelow +6 more
2012Autophagy40 citations Open access
Semantic Scholar
Critical band 3 multiprotein complex interactions establish early during human erythropoiesis
T. Satchwell, Amanda J. Bell, S. Pellegrin, S. Kupzig +5 more
2011Blood40 citations Open access
Semantic Scholar
Superior survival of ex vivo cultured human reticulocytes following transfusion into mice
S. Kupzig, S. Parsons, E. Curnow, D. Anstee +1 more
2016Haematologica35 citations Open access
Semantic Scholar
The Ability of GAP1IP4BP To Function as a Rap1 GTPase-Activating Protein (GAP) Requires Its Ras GAP-Related Domain and an Arginine Finger Rather than an Asparagine Thumb
S. Kupzig, Dalila Bouyoucef-Cherchalli, Sam Yarwood, R. Sessions +1 more
2009Molecular and Cellular Biology32 citations Open access
Semantic Scholar
Reticulocyte Maturation and Variant Red Blood Cells
Christian J Stevens-Hernandez, Joanna F. Flatt, S. Kupzig, L. Bruce
2022Frontiers in Physiology30 citations Open access
Semantic Scholar
Blood group type A secretors are associated with a higher risk of COVID‐19 cardiovascular disease complications
T. Mankelow, B. Singleton, P. Moura, Christian J Stevens-Hernandez +18 more
2021eJHaem22 citations Open access
Semantic Scholar
Analyzing the Role of the Putative Inositol 1,3,4,5-Tetrakisphosphate Receptor GAP1IP4BP in Intracellular Ca2+ Homeostasis*
S. Walker, S. Kupzig, P. J. Lockyer, S. Bilu +2 more
2002Journal of Biological Chemistry19 citations Open access
Semantic Scholar
Studying the spatial and temporal regulation of Ras GTPase-activating proteins.
S. Kupzig, D. Bouyoucef, G. Cozier, P. Cullen
2006Methods in Enzymology7 citations
Semantic Scholar
Green Fluorescent Protein
S. Kupzig, San-San Lee, G. Banting
19996 citations Open access
Semantic Scholar
GFP in motion
S. Kupzig, G. Banting
19994 citations
Semantic Scholar
A Robust Ex Vivo culture System for Production of Mature Human Reticulocytes From a Single Donor
Nicola M. Cogan, S. Kupzig, S. Parsons, D. Anstee
20112 citations
Semantic Scholar
[1] Membrane trafficking
S. Kupzig, San-San Lee, G. Banting
19992 citations
Semantic Scholar
Improving the stability of cultured red blood cells during storage
Christian J Stevens-Hernandez, S. Kupzig, P. Diamanti, Nicola M. Cogan +2 more
2025Vox Sanguinis1 citations
Semantic Scholar
Ex vivo Engineering of Red Blood Cells
J. Frayne, Deborah E. Daniels, T. Satchwell, Joseph Hawksworth +13 more
2019Blood1 citations Open access
Semantic Scholar
Plasma Membrane Loss in Maturing Human Reticulocytes Occurs Through Endocytosis of Large Glycophorin A- Containing Vacuoles Which Fuse with Autophagosomes Before Exocytosis
R. Griffiths, S. Kupzig, Nicola M. Cogan, V. Betin +4 more
20111 citations
Semantic Scholar
Identification of the Ras GTPase-activating protein GAP1m as an in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein
P. J. Lockyer, Stefan Wennström, S. Kupzig, K. Venkateswarlu +2 more
19991 citations
Semantic Scholar
MANUFACTURING RED BLOOD CELLS FROM STEM CELLS; FROM BENCH TO PHASE 1 CLINICAL TRIAL
A. Blair, S. Kupzig, R. Allen, L. Bruce +8 more
2024Cytotherapy0 citations
Semantic Scholar
FACs sorting of reticulocytes and extruded nuclei.
Amanda J. Bell, T. Satchwell, K. Heesom, Bethan R. Hawley +5 more
20130 citations Open access
Semantic Scholar
Dynamics of a golgi membrane protein after redistribution into the ER.
S. Kupzig, G. Banting
19990 citations
Semantic Scholar
Golgi membrane protein dynamics.
G. Banting, S. Kupzig
19990 citations
Semantic Scholar
Membrane trafficking.
S. Kupzig, S. Lee, G. Banting
1999Methods in Enzymology0 citations
Semantic Scholar
Membrane protein dynamics in and around the trans golgi network.
S. Kupzig, G. Banting
19990 citations
Semantic Scholar
PI 3-kinase effector molecules
G. Cozier, S. Kupzig, P. J. Lockyer, J. S. Reynolds +3 more
19990 citations
Semantic Scholar
Identification and characterisation of two novel proteins of the secretory pathway.
S. Kupzig
19980 citations
Semantic Scholar

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