D. G. Gourley

Most-cited papers

1. Pteridine reductase mechanism correlates pterin metabolism with drug resistance in trypanosomatid parasites

   D. G. Gourley, A. W. Schüttelkopf, G. Leonard, J. Luba +3 more

   2001Nature Structural Biology126 citations

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2. The two types of 3-dehydroquinase have distinct structures but catalyze the same overall reaction

   D. G. Gourley, A. Shrive, I. Polikarpov, T. Krell +4 more

   1999Nature Structural Biology122 citations Open access

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3. The high‐resolution crystal structure of the molybdate‐dependent transcriptional regulator (ModE) from Escherichia coli: a novel combination of domain folds

   D. R. Hall, D. G. Gourley, Gordon A. Leonard, Elizabeth M. H. Duke +3 more

   1999EMBO Journal80 citations Open access

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4. High-resolution crystal structure of Trypanosoma brucei UDP-galactose 4'-epimerase: a potential target for structure-based development of novel trypanocides.

   M. Shaw, C. Bond, Janine R. Roper, D. G. Gourley +2 more

   2003Molecular and biochemical parasitology (Print)58 citations

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5. Oxyanion Binding Alters Conformation and Quaternary Structure of the C-terminal Domain of the Transcriptional Regulator ModE

   D. G. Gourley, A. W. Schüttelkopf, L. A. Anderson, N. C. Price +2 more

   2001Journal of Biological Chemistry37 citations Open access

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6. The High Resolution Crystal Structure of RecombinantCrithidia fasciculata Tryparedoxin-I*

   M. Alphey, G. Leonard, D. G. Gourley, E. Tetaud +2 more

   1999Journal of Biological Chemistry33 citations Open access

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7. Crystallization of a type II dehydroquinase from Mycobacterium tuberculosis.

   D. G. Gourley, J. Coggins, N. Isaacs, Jonathan D. Moore +2 more

   1994Journal of Molecular Biology32 citations

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8. The folding and assembly of the dodecameric type II dehydroquinases.

   N. C. Price, Deborah J. Boam, Sharon M. Kelly, D. Duncan +5 more

   1999Biochemical Journal24 citations Open access

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9. Crystallization of recombinant Leishmania major pteridine reductase 1 (PTR1).

   D. G. Gourley, J. Luba, L. Hardy, S. Beverley +1 more

   1999Acta Crystallographica Section D: Biological Crystallography17 citations

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10. Sensing of remote oxyanion binding at the DNA binding domain of the molybdate-dependent transcriptional regulator, ModE.

    D. H. Boxer, Han Zhang, D. G. Gourley, W. Hunter +2 more

    2004Organic and biomolecular chemistry13 citations

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11. Two crystal forms of ModE, the molybdate-dependent transcriptional regulator from Escherichia coli.

    D. R. Hall, D. G. Gourley, E. Duke, Gordon A. Leonard +4 more

    1999Acta Crystallographica Section D: Biological Crystallography6 citations

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12. Crystallization of RecombinantCrithidia fasciculataTryparedoxin

    M. Alphey, E. Tetaud, D. G. Gourley, A. Fairlamb +1 more

    19995 citations

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13. Crystallization and preliminary X-ray diffraction studies of 6-phosphogluconate dehydrogenase from Lactococcus lactis.

    Emmanuel Tetaud, D. R. Hall, D. G. Gourley, Gordon A. Leonard +3 more

    1998Acta Crystallographica Section D: Biological Crystallography2 citations

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14. Crystallization of recombinant Crithidia fasciculata tryparedoxin.

    M. Alphey, E. Tetaud, D. G. Gourley, A. Fairlamb +1 more

    1999Journal of Structural Biology1 citations

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15. Molybdate bound complex of Dimop domain of ModE from E.coli

    D. G. Gourley, W. Hunter

    20010 citations

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16. Tungstate bound complex Dimop domain of ModE from E.coli

    D. G. Gourley, W. Hunter

    20010 citations

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17. One active site, two modes of reduction correlate the mechanism of leishmania pteridine reductase with pterin metabolism and antifolate drug resistance in trpanosomes

    D. G. Gourley, W. Hunter

    20010 citations

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18. Structure and mechanism of pteridine reductase 1 from Leishmania

    A. W. Schüttelkopf, D. G. Gourley, W. Hunter

    20000 citations Open access

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19. REGULATOR FROM ESCHERICHIA COLI

    D. Hall, D. G. Gourley, W. Hunter

    20000 citations

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20. 3-DEHYDROQUINATE DEHYDRATASE FROM MYCOBACTERIUM TUBERCULOSIS

    D. G. Gourley, A. Hawkins, J. Coggins, N. Isaacs

    19990 citations

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21. CRYSTALLIZATION NOTE Crystallization of Recombinant Crithidia fasciculata Tryparedoxin

    M. Alphey, E. Tetaud, D. G. Gourley, A. Fairlamb +1 more

    19990 citations

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22. The crystal structure of a type II dehydroquinase from Mycobacterium tuberculosis

    D. G. Gourley, J. R. Coggins, A. Hawkins, N. Isaacs

    19960 citations

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23. Structural Studies on the Type II Dehydroquinase From Mycobacterium tuberculosis

    D. G. Gourley

    19960 citations

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