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T. Little · SciRah

Researcher profile · Semantic Scholar

T. Little

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T. Little — researcher profile on SciRah

h-index: 40
Works: 111
Citations: 6,533

Most-cited papers

Immunity in a variable world
B. Lazzaro, T. Little
2009Philosophical Transactions of the Royal Society B: Biological Sciences410 citations Open access
Semantic Scholar
Maternal transfer of strain-specific immunity in an invertebrate.
T. Little, Benjamin O'Connor, N. Colegrave, K. Watt +1 more
2003Current Biology359 citations Open access
Semantic Scholar
Natural selection drives extremely rapid evolution in antiviral RNAi genes.
Darren J Obbard, F. Jiggins, D. Halligan, T. Little
2006Current Biology314 citations Open access
Semantic Scholar
Invertebrate immunity and the limits of mechanistic immunology
T. Little, D. Hultmark, A. Read
2005Nature Immunology297 citations
Semantic Scholar
Ecological and evolutionary implications of immunological priming in invertebrates.
T. Little, A. Kraaijeveld
2004Trends in Ecology & Evolution255 citations Open access
Semantic Scholar
Fitness consequences of immune responses: strengthening the empirical framework for ecoimmunology
A. Graham, D. Shuker, Laura C. Pollitt, S. Auld +2 more
2011249 citations
Semantic Scholar
Universal DNA methylation age across mammalian tissues
A. Lu, Z. Fei, A. Haghani, T. Robeck +184 more
2023Nature Aging230 citations Open access
Semantic Scholar
The Evolution of Virulence When Parasites Cause Host Castration and Gigantism
D. Ebert, Hans Joachim Carius, T. Little, Ellen Decaestecker
2004American Naturalist209 citations Open access
Semantic Scholar
The Coevolution of Virulence: Tolerance in Perspective
T. Little, D. Shuker, N. Colegrave, T. Day +1 more
2010PLoS Pathogens194 citations Open access
Semantic Scholar
Empirical Support for Optimal Virulence in a Castrating Parasite
K. Jensen, T. Little, A. Skorping, D. Ebert
2006PLoS Biology169 citations Open access
Semantic Scholar
The Dscam homologue of the crustacean Daphnia is diversified by alternative splicing like in insects.
D. Brites, S. McTaggart, K. Morris, Jobriah E. Anderson +6 more
2008Molecular biology and evolution162 citations Open access
Semantic Scholar
Deforestation and Vectorial Capacity of Anopheles gambiae Giles Mosquitoes in Malaria Transmission, Kenya
Y. Afrane, T. Little, B. Lawson, A. Githeko +1 more
2008Emerging Infectious Diseases150 citations Open access
Semantic Scholar
PARASITE-HOST SPECIFICITY: EXPERIMENTAL STUDIES ON THE BASIS OF PARASITE ADAPTATION
T. Little, K. Watt, D. Ebert
2006Evolution; international journal of organic evolution134 citations
Semantic Scholar
PARASITE-DRIVEN GENETIC CHANGE IN A NATURAL POPULATION OF DAPHNIA
A. Duncan, T. Little
2007Evolution; international journal of organic evolution125 citations
Semantic Scholar
Daphnia magna transcriptome by RNA-Seq across 12 environmental stressors
L. Orsini, D. Gilbert, R. Podicheti, Mieke Jansen +19 more
2016Scientific Data123 citations Open access
Semantic Scholar
The components of the Daphnia pulex immune system as revealed by complete genome sequencing
S. McTaggart, Claire Conlon, J. Colbourne, M. Blaxter +1 more
2009BMC Genomics117 citations Open access
Semantic Scholar
Temperature‐dependent costs of parasitism and maintenance of polymorphism under genotype‐by‐environment interactions
P. Vale, M. Stjernman, T. Little
2008Journal of Evolutionary Biology113 citations Open access
Semantic Scholar
The evolutionary signi®cance of parasitism: do parasite-driven genetic dynamics occur ex silico?
T. Little
2002113 citations
Semantic Scholar
Epidemiological, evolutionary and co-evolutionary implications of context-dependent parasitism
P. Vale, Alastair J. Wilson, A. Best, M. Boots +1 more
2011American Naturalist109 citations Open access
Semantic Scholar
A parasite-mediated life-history shift in Daphnia magna
W. Chadwick, T. Little
2005Proceedings of the Royal Society of London. Biological Sciences107 citations Open access
Semantic Scholar
CRISPR-mediated phage resistance and the ghost of coevolution past
P. Vale, T. Little
2010Proceedings of the Royal Society of London. Biological Sciences94 citations Open access
Semantic Scholar
Fecundity compensation and tolerance to a sterilizing pathogen in Daphnia
P. Vale, T. Little
2012Journal of Evolutionary Biology78 citations Open access
Semantic Scholar
Parasite‐mediated selection and the role of sex and diapause in Daphnia
Alison B. Duncan, S. Mitchell, T. Little
2006Journal of Evolutionary Biology71 citations Open access
Semantic Scholar
Host nutrition alters the variance in parasite transmission potential
P. Vale, Marc Choisy, T. Little
2013Biology Letters69 citations Open access
Semantic Scholar
Recent and Recurrent Selective Sweeps of the Antiviral RNAi Gene Argonaute-2 in Three Species of Drosophila
Darren J Obbard, F. Jiggins, N. Bradshaw, T. Little
2010Molecular biology and evolution68 citations Open access
Semantic Scholar
The evolution of TEP1, an exceptionally polymorphic immunity gene in Anopheles gambiae
Darren J Obbard, Deborah M. Callister, F. Jiggins, Dinesh C. Soares +2 more
2008BMC Evolutionary Biology64 citations Open access
Semantic Scholar
The effect of a pathogen epidemic on the genetic structure and reproductive strategy of the crustacean Daphnia magna
S. E. Mitchell, A. Read, T. Little
200464 citations
Semantic Scholar
Elevated maternal temperature enhances offspring disease resistance in Daphnia magna
Jennie S. Garbutt, J. Scholefield, P. Vale, T. Little
201460 citations Open access
Semantic Scholar
Immune genes undergo more adaptive evolution than non-immune system genes in Daphnia pulex
S. McTaggart, Darren J Obbard, Claire Conlon, T. Little
2012BMC Evolutionary Biology60 citations Open access
Semantic Scholar
HOST-PARASITE AND GENOTYPE-BY-ENVIRONMENT INTERACTIONS: TEMPERATURE MODIFIES POTENTIAL FOR SELECTION BY A STERILIZING PATHOGEN
S. E. Mitchell, Emily S. Rogers, T. Little, A. Read
200556 citations
Semantic Scholar
Maternal food quantity affects offspring feeding rate in Daphnia magna
Jennie S. Garbutt, T. Little
2014Biology Letters53 citations Open access
Semantic Scholar
Molecular Evolution of Daphnia Immunity Genes: Polymorphism in a Gram-Negative Binding Protein Gene and an α-2-Macroglobulin Gene
T. Little, J. Colbourne, T. Crease
2004Journal of Molecular Evolution53 citations
Semantic Scholar
Mitogenome phylogeographic analysis of a planktonic crustacean.
P. Fields, Darren J Obbard, S. McTaggart, Y. Galimov +2 more
2018Molecular Phylogenetics and Evolution49 citations Open access
Semantic Scholar
Evidence for a cost of immunity when the crustacean Daphnia magna is exposed to the bacterial pathogen Pasteuria ramosa.
T. Little, Stuart C. Killick
2007Journal of Animal Ecology47 citations Open access
Semantic Scholar
The evolution of immune‐related genes from disease carrying mosquitoes: diversity in a peptidoglycan‐ and a thioester‐recognizing protein
T. Little, N. Cobbe
2005Insect molecular biology (Print)45 citations
Semantic Scholar
Daphnia magna shows reduced infection upon secondary exposure to a pathogen
S. McTaggart, Phil J. Wilson, T. Little
2012Biology Letters39 citations Open access
Semantic Scholar
Successfully resisting a pathogen is rarely costly in Daphnia magna
P. Labbé, P. Vale, T. Little
2010BMC Evolutionary Biology38 citations Open access
Semantic Scholar
Nucleotide Polymorphism and Within-Gene Recombination in Daphnia magna and D. pulex, Two Cyclical Parthenogens
C. Haag, S. McTaggart, Anaïs Didier, T. Little +1 more
2009Genetics38 citations Open access
Semantic Scholar
Population genetics of Plasmodium resistance genes in Anopheles gambiae: no evidence for strong selection
Darren J Obbard, Y. Linton, F. Jiggins, G. Yan +1 more
2007Molecular Ecology38 citations Open access
Semantic Scholar
The Course of Malaria in Mice: Major Histocompatibility Complex (MHC) Effects, but No General MHC Heterozygote Advantage in Single-Strain Infections
C. Wedekind, M. Walker, T. Little
2005Genetics38 citations
Semantic Scholar
Explorer Alternative splicing of the Anopheles gambiae Dscam gene in diverse Plasmodium falciparum infections
Paul H. Smith, Jonathan M. Mwangi, Y. Afrane, G. Yan +3 more
201737 citations
Semantic Scholar
ProPhenolOxidase in Daphnia magna: cDNA sequencing and expression in relation to resistance to pathogens.
P. Labbé, T. Little
2009Developmental and Comparative Immunology37 citations
Semantic Scholar
( Crustacea : Cladocera ) to its bacterial parasite Daphnia magna Genetic variation in the cellular response of
S. Auld, J. Scholefield, T. Little
201034 citations
Semantic Scholar
Parasite variation and the evolution of virulence in a Daphnia-microparasite system
T. Little, W. Chadwick, K. Watt
2007Parasitology34 citations Open access
Semantic Scholar
An ancient immunity gene duplication in Daphnia magna: RNA expression and sequence analysis of two nitric oxide synthase genes
P. Labbé, S. McTaggart, T. Little
2009Developmental and Comparative Immunology32 citations Open access
Semantic Scholar
Disease spread in age structured populations with maternal age effects
Jessica Clark, Jennie S. Garbutt, L. McNally, T. Little
2017Ecology Letters31 citations Open access
Semantic Scholar
Genome-wide methylation is modified by caloric restriction in Daphnia magna
J. Hearn, M. Pearson, M. Blaxter, Phil J. Wilson +1 more
2019BMC Genomics30 citations Open access
Semantic Scholar
A shared mechanism of defense against predators and parasites: chitin regulation and its implications for life-history theory
A. Beckerman, Job de Roij, Stuart R. Dennis, T. Little
2013Ecology and Evolution30 citations Open access
Semantic Scholar
Testing Small Clutch Size Models with Daphnia
M. Guinnee, S. West, T. Little
2004American Naturalist30 citations
Semantic Scholar
Identifying energy constraints to parasite resistance
D. Allen, T. Little
2011Journal of Evolutionary Biology29 citations Open access
Semantic Scholar

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