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G. Picolo · SciRah

Researcher profile · Semantic Scholar

G. Picolo

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G. Picolo — researcher profile on SciRah

h-index: 24
Works: 70
Citations: 1,903

Most-cited papers

Pain and analgesia: The dual effect of nitric oxide in the nociceptive system.
Y. Cury, G. Picolo, V. Gutierrez, S. H. Ferreira
2011Nitric oxide307 citations
Semantic Scholar
Inflammation induced by Bothrops asper venom.
Catarina de Fátima Pereira Teixeira, Y. Cury, Vanessa Moreira, G. Picolo +1 more
2009Toxicon137 citations Open access
Semantic Scholar
Analgesic Effect of He-Ne (632.8 nm) Low-Level Laser Therapy on Acute Inflammatory Pain
Denise M. Ferreira, Renato Amaro Zângaro, A. Villaverde, Y. Cury +4 more
2005Photomedicine and Laser Surgery127 citations
Semantic Scholar
Hyperalgesia induced by Asp49 and Lys49 phospholipases A2 from Bothrops asper snake venom: pharmacological mediation and molecular determinants.
M. Chacur, I. Longo, G. Picolo, J. Gutiérrez +4 more
2003Toxicon91 citations Open access
Semantic Scholar
Secreted Phospholipases A2 from Animal Venoms in Pain and Analgesia
V. Zambelli, G. Picolo, C. Fernandes, M. Fontes +1 more
2017Toxins78 citations Open access
Semantic Scholar
Crotalphine, a novel potent analgesic peptide from the venom of the South American rattlesnake Crotalus durissus terrificus.
K. Konno, G. Picolo, V. Gutierrez, P. Brigatte +3 more
2008Peptides77 citations
Semantic Scholar
Pharmacological modulation of hyperalgesia induced by Bothrops asper (terciopelo) snake venom.
M. Chacur, G. Picolo, J. Gutiérrez, Catarina Teixeira +1 more
2001Toxicon69 citations Open access
Semantic Scholar
How environmental enrichment balances out neuroinflammation in chronic pain and comorbid depression and anxiety disorders
L. F. Kimura, L. S. Novaes, G. Picolo, C. Munhoz +2 more
2021British Journal of Pharmacology59 citations Open access
Semantic Scholar
Crotalphine induces potent antinociception in neuropathic pain by acting at peripheral opioid receptors.
V. Gutierrez, K. Konno, M. Chacur, S. C. Sampaio +4 more
2008European Journal of Pharmacology57 citations
Semantic Scholar
delta-opioid receptors and nitric oxide mediate the analgesic effect of Crotalus durissus terrificus snake venom.
G. Picolo, Renata Giorgi, Yara Cury
2000European Journal of Pharmacology57 citations
Semantic Scholar
Evaluation of antivenoms in the neutralization of hyperalgesia and edema induced by Bothrops jararaca and Bothrops asper snake venoms.
G. Picolo, M. Chacur, J. Gutiérrez, Catarina de Fátima Pereira Teixeira +1 more
2002Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas55 citations Open access
Semantic Scholar
Activation of peripheral ATP-sensitive K+ channels mediates the antinociceptive effect of Crotalus durissus terrificus snake venom.
G. Picolo, A. Cassola, Y. Cury
2003European Journal of Pharmacology52 citations
Semantic Scholar
Crotalphine desensitizes TRPA1 ion channels to alleviate inflammatory hyperalgesia
E. Bressan, F. Touška, I. Vetter, K. Kistner +8 more
2016Pain47 citations
Semantic Scholar
Harnessing the knowledge of animal toxins to generate drugs.
V. Zambelli, K. Pasqualoto, G. Picolo, A. Chudzinski-Tavassi +1 more
2016Pharmacological Research44 citations
Semantic Scholar
Peripheral interactions between cannabinoid and opioid systems contribute to the antinociceptive effect of crotalphine
F. C. Machado, V. Zambelli, A. Fernandes, A. Heimann +2 more
2014British Journal of Pharmacology40 citations Open access
Semantic Scholar
Peripheral neuronal nitric oxide synthase activity mediates the antinociceptive effect of Crotalus durissus terrificus snake venom, a delta- and kappa-opioid receptor agonist.
G. Picolo, Y. Cury
2004Life Science40 citations
Semantic Scholar
Bradykinin-related peptides in the venom of the solitary wasp Cyphononyx fulvognathus.
G. Picolo, M. Hisada, Ana Moura, Mauricio F. M. Machado +8 more
2010Biochemical Pharmacology37 citations Open access
Semantic Scholar
The analgesic effect of crotoxin on neuropathic pain is mediated by central muscarinic receptors and 5-lipoxygenase-derived mediators.
Francisco de Sousa Nogueira-Neto, R. L. Amorim, P. Brigatte, G. Picolo +7 more
2008Pharmacology, Biochemistry and Behavior33 citations
Semantic Scholar
The peripheral L-arginine–nitric oxide–cyclic GMP pathway and ATP-sensitive K+ channels are involved in the antinociceptive effect of crotalphine on neuropathic pain in rats
V. Gutierrez, V. Zambelli, G. Picolo, M. Chacur +4 more
2012Behavioural Pharmacology32 citations
Semantic Scholar
Distinct environmental enrichment protocols reduce anxiety but differentially modulate pain sensitivity in rats.
L. F. Kimura, Vânia Gomes de Moura Mattaraia, G. Picolo
2017Behavioural Brain Research29 citations
Semantic Scholar
Animal toxins as analgesics--an overview.
Y. Cury, G. Picolo
2006Drug News and Perspectives29 citations
Semantic Scholar
Bradykinin is involved in hyperalgesia induced by Bothrops jararaca venom.
M. Chacur, G. Picolo, C. Teixeira, Y. Cury
2002Toxicon28 citations
Semantic Scholar
Crotoxin down-modulates pro-inflammatory cells and alleviates pain on the MOG35-55-induced experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis.
N. B. Teixeira, M. B. Sant'Anna, A. C. Giardini, Leandro Pires Araujo +4 more
2019Brain, behavior, and immunity27 citations Open access
Semantic Scholar
The antinociceptive effect of Crotalus durissus terrificus snake venom is mainly due to a supraspinally integrated response.
G. Picolo, Renata Giorgi, Maria Martha Bernardi, Yara Cury
1998Toxicon24 citations
Semantic Scholar
Pharmacological characterization of crotamine effects on mice hind limb paralysis employing both ex vivo and in vivo assays: Insights into the involvement of voltage-gated ion channels in the crotamine action on skeletal muscles
Sunamita de Carvalho Lima, Lucas de Carvalho Porta, Alvaro da Costa Lima, J. D. Campeiro +8 more
2018PLoS Neglected Tropical Diseases23 citations Open access
Semantic Scholar
Bunodosine 391: an analgesic acylamino acid from the venom of the sea anemone Bunodosoma cangicum.
A. J. Zaharenko, G. Picolo, W. Ferreira, T. Murakami +6 more
2011Journal of Natural Products23 citations
Semantic Scholar
Crotoxin Conjugated to SBA-15 Nanostructured Mesoporous Silica Induces Long-Last Analgesic Effect in the Neuropathic Pain Model in Mice
M. B. Sant'Anna, F. S. Lopes, L. F. Kimura, A. C. Giardini +2 more
2019Toxins22 citations Open access
Semantic Scholar
Periaqueductal gray μ and κ opioid receptors determine behavioral selection from maternal to predatory behavior in lactating rats.
Marianne O. Klein, A. de Mello Cruz, F. C. Machado, G. Picolo +2 more
2014Behavioural Brain Research22 citations
Semantic Scholar
Peripheral kappa and delta opioid receptors are involved in the antinociceptive effect of crotalphine in a rat model of cancer pain.
P. Brigatte, K. Konno, V. Gutierrez, S. C. Sampaio +4 more
2013Pharmacology, Biochemistry and Behavior22 citations
Semantic Scholar
Human Sensory Neuron-like Cells and Glycated Collagen Matrix as a Model for the Screening of Analgesic Compounds
M. Bufalo, M. E. S. de Almeida, J. Jensen, C. DeOcesano-Pereira +6 more
2022Cells19 citations Open access
Semantic Scholar
Mitogen-Activated Protein Kinase Signaling Mediates Morphine Induced-Delayed Hyperalgesia
B. G. de Freitas, L. M. Pereira, F. Santa-Cecília, N. Hösch +3 more
2019Frontiers in Neuroscience18 citations Open access
Semantic Scholar
Environmental factors and their impact on chronic pain development and maintenance.
M. B. Sant'Anna, L. F. Kimura, W. F. Vieira, V. Zambelli +3 more
2024Physics of Life Reviews16 citations
Semantic Scholar
Crotalphine Modulates Microglia M1/M2 Phenotypes and Induces Spinal Analgesia Mediated by Opioid-Cannabinoid Systems
F. S. Lopes, A. C. Giardini, M. B. Sant'Anna, L. F. Kimura +4 more
2022International Journal of Molecular Sciences16 citations Open access
Semantic Scholar
Crotalphine Attenuates Pain and Neuroinflammation Induced by Experimental Autoimmune Encephalomyelitis in Mice
Aline C Giardini, B. G. Evangelista, M. B. Sant'Anna, B. B. Martins +7 more
2021Toxins14 citations Open access
Semantic Scholar
The Crotoxin:SBA-15 Complex Down-Regulates the Incidence and Intensity of Experimental Autoimmune Encephalomyelitis Through Peripheral and Central Actions
M. B. Sant'Anna, A. C. Giardini, M. A. Ribeiro, F. S. Lopes +10 more
2020Frontiers in Immunology14 citations Open access
Semantic Scholar
Alterations of peripheral nerve excitability in an experimental autoimmune encephalomyelitis mouse model for multiple sclerosis
N. B. Teixeira, G. Picolo, A. C. Giardini, F. Boumezbeur +4 more
2020Journal of Neuroinflammation12 citations Open access
Semantic Scholar
Early exposure to environmental enrichment protects male rats against neuropathic pain development after nerve injury.
L. F. Kimura, M. B. Sant'Anna, V. Zambelli, A. C. Giardini +5 more
2020Experimental Neurology12 citations
Semantic Scholar
Caspase-1 and Cathepsin B Inhibitors from Marine Invertebrates, Aiming at a Reduction in Neuroinflammation
Rafaela Indalecio Moreno, V. Zambelli, G. Picolo, Y. Cury +3 more
2022Marine Drugs11 citations Open access
Semantic Scholar
Peripheral 5-HT3 Receptors Are Involved in the Antinociceptive Effect of Bunodosine 391
W. Ferreira, A. J. Zaharenko, Kohei Kazuma, G. Picolo +4 more
2017Toxins11 citations Open access
Semantic Scholar
NFKF is a synthetic fragment derived from rat hemopressin that protects mice from neurodegeneration.
A. Heimann, A. C. Giardini, M. B. Sant'Anna, N. D. Dos Santos +6 more
2020Neuroscience Letters10 citations Open access
Semantic Scholar
Box Jellyfish (Cnidaria, Cubozoa) Extract Increases Neuron's Connection: A Possible Neuroprotector Effect
Gian Lucas M. Arruda, H. Vigerelli, M. Bufalo, G. Longato +7 more
2021BioMed Research International9 citations Open access
Semantic Scholar
Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect
Renata G. Dias, S. C. Sampaio, M. B. Sant'Anna, F. Cunha +4 more
2017Journal of Venomous Animals and Toxins including Tropical Diseases9 citations Open access
Semantic Scholar
Snake and arthropod venoms: Search for inflammatory activity in human cells involved in joint diseases.
M. Alvarez-Flores, Isabel de Fátima Correia Batista, I. M. Villas Boas, M. Bufalo +11 more
2023Toxicon8 citations Open access
Semantic Scholar
Cytotoxic effect of crotoxin on cancer cells and its antitumoral effects correlated to tumor microenvironment: A review.
T. C. Almeida, Lorena de Morais Ribeiro Silva, A. M. D. de Oliveira, F. S. Lopes +2 more
2023International Journal of Biological Macromolecules7 citations
Semantic Scholar
COVID-19 induces proatherogenic alterations in moderate to severe non-comorbid patients: A single-center observational study
L. F. Kimura, M. B. Sant'Anna, S. Andrade, M. C. Ebram +4 more
2021Blood Cells, Molecules & Diseases7 citations Open access
Semantic Scholar
Potamotrygon motoro stingray venom induces both neurogenic and inflammatory pain behavior in rodents
L. F. Kimura, M. Santos-Neto, K. C. Barbaro, G. Picolo
2018Toxicon7 citations
Semantic Scholar
Pain and Cellular Migration Induced by Bothrops jararaca Venom in Mice Selected for an Acute Inflammatory Response: Involvement of Mast Cells
F. V. Kondo, W. Cabrera, O. Ribeiro, M. De Franco +7 more
2022Frontiers in Immunology5 citations Open access
Semantic Scholar
PKCζ-Mitogen-Activated Protein Kinase Signaling Mediates Crotalphine-Induced Antinociception
B. G. de Freitas, N. Hösch, L. M. Pereira, T. C. Barbosa +3 more
2021Toxins5 citations Open access
Semantic Scholar
Neurotoxicity of Olindias sambaquiensis and Chiropsalmus quadrumanus extracts in sympathetic nervous system.
T. C. Bueno, Rita de Cássia Collaço, Bianca Aparecida Cardoso, R. F. Bredariol +11 more
2021Toxicon5 citations Open access
Semantic Scholar
Crotoxin induces analgesic and immunomodulatory effects on chronic pain models that are potentiated by nanostructured silica SBA-15.
G. Picolo
2020Toxicon1 citations
Semantic Scholar

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Y. Cury×30
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Y. Cury — researcher profile on SciRah
V. Zambelli×18
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V. Zambelli — researcher profile on SciRah
M. B. Sant'Anna×12
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M. B. Sant'Anna — researcher profile on SciRah
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V. Gutierrez — researcher profile on SciRah

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M. Chacur — researcher profile on SciRah

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A. C. Giardini — researcher profile on SciRah

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P. Brigatte — researcher profile on SciRah

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S. C. Sampaio — researcher profile on SciRah

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N. B. Teixeira — researcher profile on SciRah

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M. Bufalo — researcher profile on SciRah