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Sung-Wan An · SciRah

Researcher profile · Semantic Scholar

Sung-Wan An

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Sung-Wan An — researcher profile on SciRah

h-index: 13
Works: 24
Citations: 1,341

Most-cited papers

Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart
Jian Xie, S. Cha, Sung-Wan An, M. Kuro-o +2 more
2012Nature Communications323 citations Open access
Semantic Scholar
Soluble Klotho Protects against Uremic Cardiomyopathy Independently of Fibroblast Growth Factor 23 and Phosphate.
Jian Xie, Joonho Yoon, Sung-Wan An, M. Kuro-o +1 more
2015Journal of the American Society of Nephrology250 citations Open access
Semantic Scholar
New Insights into the Mechanism of Action of Soluble Klotho
George D. Dalton, Jian Xie, Sung-Wan An, Chou-Long Huang
2017Frontiers in Endocrinology196 citations Open access
Semantic Scholar
DGKE variants cause a glomerular microangiopathy that mimics membranoproliferative GN.
F. Ozaltin, Bing-Hua Li, Alysha A Rauhauser, Sung-Wan An +29 more
2013Journal of the American Society of Nephrology149 citations Open access
Semantic Scholar
Inhibition of TRPC6 channels ameliorates renal fibrosis and contributes to renal protection by soluble klotho
Yueh-Lin Wu, Jian Xie, Sung-Wan An, N. Oliver +4 more
2016Kidney International101 citations Open access
Semantic Scholar
Soluble klotho binds monosialoganglioside to regulate membrane microdomains and growth factor signaling
George D. Dalton, Sung-Wan An, Saif I. Al-Juboori, Nicole Nischan +8 more
2017Proceedings of the National Academy of Sciences of the United States of America82 citations Open access
Semantic Scholar
Klotho Up-regulates Renal Calcium Channel Transient Receptor Potential Vanilloid 5 (TRPV5) by Intra- and Extracellular N-glycosylation-dependent Mechanisms*
M. T. Wolf, Sung-Wan An, Mingzhu Nie, M. Bal +1 more
2014Journal of Biological Chemistry68 citations Open access
Semantic Scholar
WNK1 Promotes PIP2 Synthesis to Coordinate Growth Factor and GPCR-Gq Signaling
Sung-Wan An, S. Cha, Joonho Yoon, Seungwoo Chang +2 more
2011Current Biology35 citations Open access
Semantic Scholar
Soluble klotho regulates TRPC6 calcium signaling via lipid rafts, independent of the FGFR‐FGF23 pathway
Jon D. Wright, Sung-Wan An, Jian Xie, C. Lim +1 more
2019The FASEB Journal31 citations Open access
Semantic Scholar
OSR1 regulates a subset of inward rectifier potassium channels via a binding motif variant
Clinton A. Taylor, Sung-Wan An, Sachith Gallolu Kankanamalage, S. Stippec +6 more
2018Proceedings of the National Academy of Sciences of the United States of America31 citations Open access
Semantic Scholar
Modeled structural basis for the recognition of α2–3‐sialyllactose by soluble Klotho
Jon D. Wright, Sung-Wan An, Jian Xie, Joonho Yoon +5 more
2017The FASEB Journal29 citations Open access
Semantic Scholar
Gentamicin Inhibits Ca2+ Channel TRPV5 and Induces Calciuresis Independent of the Calcium-Sensing Receptor–Claudin-14 Pathway
W. V. van Megen, Megan R Beggs, Sung-Wan An, Patrícia Ferreira +4 more
2022Journal of the American Society of Nephrology19 citations Open access
Semantic Scholar
Chloride oscillation in pacemaker neurons regulates circadian rhythms through a chloride-sensing WNK kinase signaling cascade
Jeffrey N. Schellinger, Qi-Fei Sun, John M. Pleinis, Sung-Wan An +6 more
2021bioRxiv15 citations Open access
Semantic Scholar
Munc13 mediates klotho-inhibitable diacylglycerol-stimulated exocytotic insertion of pre-docked TRPC6 vesicles
Jian Xie, Sung-Wan An, Xin Jin, Yuan Gui +1 more
2020PLoS ONE7 citations Open access
Semantic Scholar
5E- and 5Z-farnesylacetones from Sargassum siliquastrum as novel selective L-type calcium channel blockers.
W. Shin, Sangtae Oh, Sung-Wan An, G. Park +4 more
2013Vascular pharmacology6 citations
Semantic Scholar
Ghrelin enhances tubular magnesium absorption in the kidney
Mingzhu Nie, Jing Zhang, Manjot S. Bal, Claudia Duran +6 more
2024Frontiers in Physiology2 citations Open access
Semantic Scholar
Chemical Synthesis and Antifibrotic Properties of (±)-Cochlearol T, (±)-Ganocochlearin A, and (±)-Cochlearol Y.
Badrinath N. Kakde, Sung-Wan An, Yaashmin S. Jebaraj, S. Neelam +2 more
2024ACS Medicinal Chemistry Letters1 citations
Semantic Scholar
Urinary Proteins Uromodulin and Mucin-1 Physically Interact and Synergistically Stimulate the Magnesium Channel TRPM6
M. T. Wolf, Jing Zhang, Joost G. J. Hoenderop, Sung-Wan An
2025Journal of the American Society of Nephrology0 citations
Semantic Scholar
Developing New Therapies for Autosomal Dominant Tubulointerstitial Kidney Disease Caused by Uromodulin Mutations by Screening a Small Molecule Library
M. T. Wolf, Rory Anthony Sebastian, Krish Patel, Sung-Wan An +1 more
2024Journal of the American Society of Nephrology0 citations
Semantic Scholar
Mucin 1 Stimulates TRPM6 Single-Channel Activity and Cell Surface Abundance by Impairing Dynamin-Dependent TRPM6 Endocytosis
M. T. Wolf, Jing Zhang, J. Kozlitina, Joost G. J. Hoenderop +1 more
2024Journal of the American Society of Nephrology0 citations
Semantic Scholar
Insulin Receptor Substrate 4 (IRS4) Contributes to Hypomagnesemia by Mediating the Insulin Effect on the Renal Magnesium Channel TRPM6
M. T. Wolf, Jing Zhang, Sudha Neeam, Anuja Bhatta +4 more
2022Journal of the American Society of Nephrology0 citations
Semantic Scholar
Gentamicin induces calciuresis by blocking TRPV5
Wouter H. Megen, Megan R Beggs, Sung-Wan An, P. Ferreira +4 more
2022The FASEB Journal0 citations
Semantic Scholar
Insulin receptor substrate 4 deficiency mediates the insulin effect on the epithelial magnesium channel TRPM6 and causes hypomagnesemia
Jing Zhang, Sung-Wan An, S. Neelam, Anuja Bhatta +11 more
2022bioRxiv0 citations Open access
Semantic Scholar
Protein‐Protein Interaction Prediction Yields WNK‐SPAK/OSR1 Pathway as Regulator of Kir2.1 and Kir2.3 K+ Channels
Clinton A. Taylor, Sung-Wan An, Sachith Gallolu Kankanamalage, Chou-Long Huang +1 more
20180 citations
Semantic Scholar

Frequent co-authors

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Chou-Long Huang×14
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Chou-Long Huang — researcher profile on SciRah
Jian Xie×8
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M. T. Wolf×5
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Joonho Yoon×4
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Mingzhu Nie — researcher profile on SciRah

Matthias T Wolf×3

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Jing Zhang — researcher profile on SciRah

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S. Cha — researcher profile on SciRah

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M. Kuro-o — researcher profile on SciRah

George D. Dalton×2

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George D. Dalton — researcher profile on SciRah

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N. Oliver — researcher profile on SciRah