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I. Duignan · SciRah

Researcher profile · Semantic Scholar

I. Duignan

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I. Duignan — researcher profile on SciRah

h-index: 11
Works: 22
Citations: 500

Most-cited papers

Platelet-Derived Growth Factor-AB Promotes the Generation of Adult Bone Marrow–Derived Cardiac Myocytes
Munira Xaymardan, Li-Long Tang, Leze Zagreda, B. Pallante +8 more
2004Circulation Research91 citations Open access
Semantic Scholar
Vascular tenascin‐C regulates cardiac endothelial phenotype and neovascularization
V. Ballard, Arti Sharma, I. Duignan, Jacquelyne M. Holm +5 more
2006The FASEB Journal87 citations
Semantic Scholar
Bone Marrow Oct3/4+ Cells Differentiate Into Cardiac Myocytes via Age-Dependent Paracrine Mechanisms
B. Pallante, I. Duignan, D. Okin, Andrew Chin +3 more
2007Circulation Research71 citations
Semantic Scholar
BDNF-mediated enhancement of inflammation and injury in the aging heart.
D. Cai, Jacquelyne M. Holm, I. Duignan, Jin-Gang Zheng +5 more
2006Physiological Genomics66 citations
Semantic Scholar
Senescent Impairment in Synergistic Cytokine Pathways That Provide Rapid Cardioprotection in the Rat Heart
Munira Xaymardan, Jin-Gang Zheng, I. Duignan, Andrew Chin +3 more
2004Journal of Experimental Medicine46 citations Open access
Semantic Scholar
Stromal platelet-derived growth factor receptor α (PDGFRα) provides a therapeutic target independent of tumor cell PDGFRα expression in lung cancer xenografts
D. Gerber, Puja Gupta, M. Dellinger, Jason E. Toombs +7 more
2012Molecular Cancer Therapeutics37 citations Open access
Semantic Scholar
Growth factor-mediated reversal of senescent dysfunction of ischemia-induced cardioprotection.
Jin-Gang Zheng, Andrew Chin, I. Duignan, Kyungheon Won +2 more
2006American Journal of Physiology. Heart and Circulatory Physiology24 citations
Semantic Scholar
Pleiotropic stromal effects of vascular endothelial growth factor receptor 2 antibody therapy in renal cell carcinoma models.
I. Duignan, E. Corcoran, A. Pennello, M. Plym +9 more
2011Neoplasia21 citations Open access
Semantic Scholar
Platelet-derived growth factor improves cardiac function in a rodent myocardial infarction model
Jin-Gang Zheng, Jin H. Shin, Munira Xaymardan, Andrew Chin +3 more
2004Coronary Artery Disease16 citations
Semantic Scholar
A human monoclonal antibody targeting the stem cell factor receptor (c-Kit) blocks tumor cell signaling and inhibits tumor growth
Maria B. Lebron, L. Brennan, C. Damoci, M. Prewett +15 more
2014Cancer Biology & Therapy13 citations Open access
Semantic Scholar
Synergistic targeting with bone marrow-derived cells and PDGF improves diabetic vascular function.
David Klibansky, Andrew Chin, I. Duignan, J. Edelberg
2006American Journal of Physiology. Heart and Circulatory Physiology12 citations
Semantic Scholar
PDGF-AB-based functional cardioprotection of the aging rat heart.
Andrew Chin, Jin-Gang Zheng, I. Duignan, J. Edelberg
2006Experimental Gerontology8 citations
Semantic Scholar
Phage display identification of age-associated TNFalpha-mediated cardiac oxidative induction.
J. Edelberg, A. Wong, Jacquelyne M. Holm, Munira Xaymardan +4 more
2004Physiological Genomics5 citations
Semantic Scholar
Preclinical Development Stromal Platelet-Derived Growth Factor Receptor a ( PDGFR a ) Provides a Therapeutic Target Independent of Tumor Cell PDGFR a Expression in Lung Cancer Xenografts
D. Gerber, Puja Gupta, M. Dellinger, Jason E. Toombs +7 more
20124 citations
Semantic Scholar
Aging and Cardiovascular Angiogenesis Models
Andrew Chin, Jacquelyne M. Holm, I. Duignan, J. Edelberg
20061 citations
Semantic Scholar
34 Efficacy of VEGFR2 Targeted mAb Therapy in Preclinical Colorectal Cancer Model Resistant to Anti-VEGF mAb Therapy
D. Surguladze, J. Malaby, M. Prewett, I. Duignan +4 more
20120 citations
Semantic Scholar
483 Pleiotropic stromal effects of VEGFR2 antibody therapy in renal cell carcinoma models
I. Duignan, E. Corcoran, A. Pennello, M. Plym +5 more
20100 citations
Semantic Scholar
52 POSTER VEGFR2 targeted antibody and small molecule combinations in renal cell and hepatocellular cancer models
J. Tonra, E. Corcoran, I. Duignan, M. Plym +4 more
20080 citations
Semantic Scholar
536 POSTER Comparison of the tumor growth inhibitory effects of tumor cell and non-tumor cell EGFR targeted antibodies in cancer models
D. Surguladze, M. Plym, I. Duignan, M. Prewett +4 more
20080 citations
Semantic Scholar
Restoration of cardiac angiogenesis in aging female mice: identification of a novel estrogen‐tenascin‐C inductive pathway
V. Ballard, Munira Xaymardan, Andrew Chin, I. Duignan +2 more
20060 citations
Semantic Scholar
TENASCIN-C, A MEDIATOR OF PDGF SIGNALING, PROMOTES CARDIAC ANGIOGENIC MECHANISMS
V. Ballard, Munira Xaymardan, I. Duignan, Andrew Chin +1 more
20040 citations
Semantic Scholar
HETEROGENEITY OF ADULT BONE MARROW ENDOTHELIAL PRECURSOR CELLS
Munira Xaymardan, Jing-Qian Zhen, I. Duignan, Andrew Chin +1 more
20040 citations
Semantic Scholar

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J. Edelberg×13
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